Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: PROMOTER REGIONS, GENETIC - , . Treffer: 45

2017

Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 [OPEN ACCESS]
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Ofner, R; Ritter, C; Heidenreich, B; Kumar, R; Ugurel, S; Schrama, D; Becker, JC Distribution of TERT promoter mutations in primary and metastatic melanomas in Austrian patients.
J Cancer Res Clin Oncol. 2017; 143(4):613-617 [OPEN ACCESS]
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2016

Prokesch, A; Pelzmann, HJ; Pessentheiner, AR; Huber, K; Madreiter-Sokolowski, CT; Drougard, A; Schittmayer, M; Kolb, D; Magnes, C; Trausinger, G; Graier, WF; Birner-Gruenberger, R; Pospisilik, JA; Bogner-Strauss, JG N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes.
Sci Rep. 2016; 6(5):23723-23723 [OPEN ACCESS]
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2015

Jagadeeshan, S; Krishnamoorthy, YR; Singhal, M; Subramanian, A; Mavuluri, J; Lakshmi, A; Roshini, A; Baskar, G; Ravi, M; Joseph, LD; Sadasivan, K; Krishnan, A; Nair, AS; Venkatraman, G; Rayala, SK Transcriptional regulation of fibronectin by p21-activated kinase-1 modulates pancreatic tumorigenesis.
Oncogene. 2015; 34(4):455-464
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Knabl, J; Hiden, U; Hüttenbrenner, R; Riedel, C; Hutter, S; Kirn, V; Günthner-Biller, M; Desoye, G; Kainer, F; Jeschke, U GDM Alters Expression of Placental Estrogen Receptor α in a Cell Type and Gender-Specific Manner.
Reprod Sci. 2015; 22(12):1488-1495 [OPEN ACCESS]
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Laszlo, V; Hoda, MA; Garay, T; Pirker, C; Ghanim, B; Klikovits, T; Dong, YW; Rozsas, A; Kenessey, I; Szirtes, I; Grusch, M; Jakopovic, M; Samarzija, M; Brcic, L; Kern, I; Rozman, A; Popper, H; Zöchbauer-Müller, S; Heller, G; Altenberger, C; Ziegler, B; Klepetko, W; Berger, W; Dome, B; Hegedus, B Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.
J Pathol. 2015; 237(2):203-214
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Shain, AH; Garrido, M; Botton, T; Talevich, E; Yeh, I; Sanborn, JZ; Chung, J; Wang, NJ; Kakavand, H; Mann, GJ; Thompson, JF; Wiesner, T; Roy, R; Olshen, AB; Gagnon, A; Gray, JW; Huh, N; Hur, JS; Busam, KJ; Scolyer, RA; Cho, RJ; Murali, R; Bastian, BC Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Nat Genet. 2015; 47(10): 1194-1199. [OPEN ACCESS]
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2014

Fröhlich, LF; Mrakovcic, M; Smole, C; Lahiri, P; Zatloukal, K Epigenetic silencing of apoptosis-inducing gene expression can be efficiently overcome by combined SAHA and TRAIL treatment in uterine sarcoma cells.
PLoS One. 2014; 9(3):e91558-e91558 [OPEN ACCESS]
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Mellitzer, A; Ruth, C; Gustafsson, C; Welch, M; Birner-Grünberger, R; Weis, R; Purkarthofer, T; Glieder, A Synergistic modular promoter and gene optimization to push cellulase secretion by Pichia pastoris beyond existing benchmarks.
J Biotechnol. 2014; 191(1):187-195
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Moazedi-Fuerst, FC; Hofner, M; Gruber, G; Weinhaeusel, A; Stradner, MH; Angerer, H; Peischler, D; Lohberger, B; Glehr, M; Leithner, A; Sonntagbauer, M; Graninger, WB Epigenetic differences in human cartilage between mild and severe OA.
J Orthop Res. 2014; 32(12):1636-1645 [OPEN ACCESS]
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Pradhan, SA; Rather, MI; Tiwari, A; Bhat, VK; Kumar, A Evidence that TSC2 acts as a transcription factor and binds to and represses the promoter of Epiregulin.
Nucleic Acids Res. 2014; 42(10): 6243-6255. [OPEN ACCESS]
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Rossmann, C; Windpassinger, C; Brunner, D; Kovacevic, A; Schweighofer, N; Malli, R; Schuligoi, R; Prokesch, A; Kluve-Beckerman, B; Graier, WF; Kratky, D; Sattler, W; Malle, E Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.
Biochem Biophys Res Commun. 2014; 450(4):1643-1649 [OPEN ACCESS]
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2013

Büttner, S; Faes, L; Reichelt, WN; Broeskamp, F; Habernig, L; Benke, S; Kourtis, N; Ruli, D; Carmona-Gutierrez, D; Eisenberg, T; D'hooge, P; Ghillebert, R; Franssens, V; Harger, A; Pieber, TR; Freudenberger, P; Kroemer, G; Sigrist, SJ; Winderickx, J; Callewaert, G; Tavernarakis, N; Madeo, F The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models.
Cell Death Differ. 2013; 20(3):465-477 [OPEN ACCESS]
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Duszka, K; Bogner-Strauss, JG; Hackl, H; Rieder, D; Neuhold, C; Prokesch, A; Trajanoski, Z; Krogsdam, AM Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue.
Mol Endocrinol. 2013; 27(1): 135-149. [OPEN ACCESS]
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Ho, JE; Chen, WY; Chen, MH; Larson, MG; McCabe, EL; Cheng, S; Ghorbani, A; Coglianese, E; Emilsson, V; Johnson, AD; Walter, S; Franceschini, N; O'Donnell, CJ; CARDIoGRAM Consortium; CHARGE Inflammation Working Group; Dehghan, A; Lu, C; Levy, D; Newton-Cheh, C; CHARGE Heart Failure Working Group; Lin, H; Felix, JF; Schreiter, ER; Vasan, RS; Januzzi, JL; Lee, RT; Wang, TJ; Assimes, TL; Deloukas, P; Erdmann, J; Holm, H; Kathiresan, S; König, IR; McPherson, R; Reilly, MP; Roberts, R; Samani, NJ; Schunkert, H; Stewart, AF Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.
J Clin Invest. 2013; 123(10): 4208-4218. [OPEN ACCESS]
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2012

Chennamsetty, I; Claudel, T; Kostner, KM; Trauner, M; Kostner, GM FGF19 signaling cascade suppresses APOA gene expression.
Arterioscler Thromb Vasc Biol. 2012; 32(5):1220-1227 [OPEN ACCESS]
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Seleznik, GM; Reding, T; Romrig, F; Saito, Y; Mildner, A; Segerer, S; Sun, LK; Regenass, S; Lech, M; Anders, HJ; McHugh, D; Kumagi, T; Hiasa, Y; Lackner, C; Haybaeck, J; Angst, E; Perren, A; Balmer, ML; Slack, E; MacPherson, A; Manz, MG; Weber, A; Browning, JL; Arkan, MC; Rülicke, T; Aguzzi, A; Prinz, M; Graf, R; Heikenwalder, M Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis.
Gastroenterology. 2012; 143(5):1361-1374 [OPEN ACCESS]
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Szkandera, J; Absenger, G; Stotz, M; Weissmueller, M; Winder, T; Langsenlehner, T; Samonigg, H; Renner, W; Schippinger, W; Gerger, A The Functional Polymorphism of Erythropoietin Gene rs1617640 G>T Is Not Associated with Susceptibility and Clinical Outcome of Early-stage Breast Cancer.
Anticancer Res. 2012; 32(8):3473-3478
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2011

Chennamsetty, I; Claudel, T; Kostner, KM; Baghdasaryan, A; Kratky, D; Levak-Frank, S; Frank, S; Gonzalez, FJ; Trauner, M; Kostner, GM Farnesoid X receptor represses hepatic human APOA gene expression.
J Clin Invest. 2011; 121(9):3724-3734 [OPEN ACCESS]
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Hallen, L; Klein, H; Stoschek, C; Wehrmeyer, S; Nonhoff, U; Ralser, M; Wilde, J; Röhr, C; Schweiger, MR; Zatloukal, K; Vingron, M; Lehrach, H; Konthur, Z; Krobitsch, S The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2.
Hum Mol Genet. 2011; 20(1): 104-114. [OPEN ACCESS]
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Schmidt, H; Zeginigg, M; Wiltgen, M; Freudenberger, P; Petrovic, K; Cavalieri, M; Gider, P; Enzinger, C; Fornage, M; Debette, S; Rotter, JI; Ikram, MA; Launer, LJ; Schmidt, R; CHARGE consortium Neurology working group Genetic variants of the NOTCH3 gene in the elderly and magnetic resonance imaging correlates of age-related cerebral small vessel disease.
Brain. 2011; 134(Pt 11): 3384-3397. [OPEN ACCESS]
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Winder, T; Bohanes, P; Zhang, W; Yang, D; Power, DG; Ning, Y; Gerger, A; Wilson, PM; Tang, LH; Shah, M; Lee, AS; Lenz, HJ GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.
Ann Oncol. 2011; 22(11):2431-2439 [OPEN ACCESS]
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2010

Bogner-Strauss, JG; Prokesch, A; Sanchez-Cabo, F; Rieder, D; Hackl, H; Duszka, K; Krogsdam, A; Di Camillo, B; Walenta, E; Klatzer, A; Lass, A; Pinent, M; Wong, WC; Eisenhaber, F; Trajanoski, Z Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARγ.
Cell Mol Life Sci. 2010; 67(23): 4049-4064.
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Jamali, S; Salzmann, A; Perroud, N; Ponsole-Lenfant, M; Cillario, J; Roll, P; Roeckel-Trevisiol, N; Crespel, A; Balzar, J; Schlachter, K; Gruber-Sedlmayr, U; Pataraia, E; Baumgartner, C; Zimprich, A; Zimprich, F; Malafosse, A; Szepetowski, P Functional variant in complement C3 gene promoter and genetic susceptibility to temporal lobe epilepsy and febrile seizures.
PLoS One. 2010; 5(9): [OPEN ACCESS]
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Müller-Tidow, C; Klein, HU; Hascher, A; Isken, F; Tickenbrock, L; Thoennissen, N; Agrawal-Singh, S; Tschanter, P; Disselhoff, C; Wang, Y; Becker, A; Thiede, C; Ehninger, G; zur Stadt, U; Koschmieder, S; Seidl, M; Müller, FU; Schmitz, W; Schlenke, P; McClelland, M; Berdel, WE; Dugas, M; Serve, H; Study Alliance Leukemia Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia.
Blood. 2010; 116(18): 3564-3571. [OPEN ACCESS]
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Wakula, P; Bisping, E; Kockskamper, J; Post, H; Brauer, S; Deuter, M; Oehlmann, R; Besenfelder, U; Lai, FA; Brem, G; Pieske, B CMV promoter is inadequate for expression of mutant human RyR2 in transgenic rabbits
J Pharmacol Toxicol Methods. 2010; 63(2):180-185
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2009

Balic, M; Pichler, M; Strutz, J; Heitzer, E; Ausch, C; Samonigg, H; Cote, RJ; Dandachi, N High quality assessment of DNA methylation in archival tissues from colorectal cancer patients using quantitative high-resolution melting analysis.
J Mol Diagn. 2009; 11(2):102-108 [OPEN ACCESS]
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Klein, K; Kullak-Ublick, GA; Wagner, M; Trauner, M; Eloranta, JJ Hepatocyte nuclear factor-4alpha and bile acids regulate human concentrative nucleoside transporter-1 gene expression.
Am J Physiol Gastrointest Liver Physiol. 2009; 296(4): G936-G947. [OPEN ACCESS]
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Lüblinghoff, N; Winkler, K; Winkelmann, BR; Seelhorst, U; Wellnitz, B; Boehm, BO; März, W; Hoffmann, MM Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (the Ludwigshafen Risk and Cardiovascular Health study).
BMC Med Genet. 2009; 10(2):36-36 [OPEN ACCESS]
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2008

Akimzhanov, A; Krenacs, L; Schlegel, T; Klein-Hessling, S; Bagdi, E; Stelkovics, E; Kondo, E; Chuvpilo, S; Wilke, P; Avots, A; Gattenlohner, S; Muller-Hermelink, HK; Palmetshofer, A; Serfling, E Epigenetic changes and suppression of the nuclear factor of activated T cell 1 (NFATC1) promoter in human lymphomas with defects in immunoreceptor signaling.
Am J Pathol. 2008; 172(1):215-224 [OPEN ACCESS]
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Hoffmann, MM; Pilz, S; Weihrauch, G; Seelhorst, U; Wellnitz, B; Winkelmann, BR; Boehm, BO; März, W Effect of the resistin -420C > G polymorphism on cardiovascular disease and mortality.
Clin Endocrinol (Oxf). 2008; 69(2): 344-345.
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Lassacher, A; Heitzer, E; Kerl, H; Wolf, P p14ARF hypermethylation is common but INK4a-ARF locus or p53 mutations are rare in Merkel cell carcinoma.
J Invest Dermatol. 2008; 128(7): 1788-1796. [OPEN ACCESS]
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Schgoer, W; Eller, P; Mueller, T; Tancevski, I; Wehinger, A; Ulmer, H; Sandhofer, A; Ritsch, A; Haltmayer, M; Patsch, JR The MTP -493TT genotype is associated with peripheral arterial disease: results from the Linz Peripheral Arterial Disease (LIPAD) Study.
Clin Biochem. 2008; 41(9):712-716
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2007

Iro, M; Klein, R; Glos, B; Baranyi, U; Rössler, N; Witte, A The lysogenic region of virus phiCh1: identification of a repressor-operator system and determination of its activity in halophilic Archaea.
Extremophiles. 2007; 11(2):383-396
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Lewander, A; Butchi, AK; Gao, J; He, LJ; Lindblom, A; Arbman, G; Carstensen, J; Zhang, ZY; Sun, XF; Swedish Low-Risk Colorectal Cancer Study Group Polymorphism in the promoter region of the NFKB1 gene increases the risk of sporadic colorectal cancer in Swedish but not in Chinese populations.
Scand J Gastroenterol. 2007; 42(11):1332-1338
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2006

Bundschu, K; Gattenlohner, S; Knobeloch, KP; Walter, U; Schuh, K Tissue-specific Spred-2 promoter activity characterized by a gene trap approach.
Gene Expr Patterns. 2006; 6(3):247-255
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Madl, T; Van Melderen, L; Mine, N; Respondek, M; Oberer, M; Keller, W; Khatai, L; Zangger, K Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA.
J Mol Biol. 2006; 364(2): 170-185.
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Uitterlinden, AG; Ralston, SH; Brandi, ML; Carey, AH; Grinberg, D; Langdahl, BL; Lips, P; Lorenc, R; Obermayer-Pietsch, B; Reeve, J; Reid, DM; Amedei, A; Amidei, A; Bassiti, A; Bustamante, M; Husted, LB; Diez-Perez, A; Dobnig, H; Dunning, AM; Enjuanes, A; Fahrleitner-Pammer, A; Fang, Y; Karczmarewicz, E; Kruk, M; van Leeuwen, JP; Mavilia, C; van Meurs, JB; Mangion, J; McGuigan, FE; Pols, HA; Renner, W; Rivadeneira, F; van Schoor, NM; Scollen, S; Sherlock, RE; Ioannidis, JP; APOSS Investigators; EPOS Investigators; EPOLOS Investigators; FAMOS Investigators; LASA Investigators; Rotterdam Study Investigators; GENOMOS Study The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis.
Ann Intern Med. 2006; 145(4):255-264 [OPEN ACCESS]
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Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Halilbasic, E; Denk, H; Marschall, HU; Trauner, M Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(5):G923-G932 [OPEN ACCESS]
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2005

Item, CB; Turhani, D; Thurnher, D; Yerit, K; Sinko, K; Wittwer, G; Adeyemo, WL; Frei, K; Erginel-Unaltuna, N; Watzinger, F; Ewers, R Van Der Woude syndrome: variable penetrance of a novel mutation (p.Arg 84Gly) of the IRF6 gene in a Turkish family.
Int J Mol Med. 2005; 15(2):247-251 (- Case Report)
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Tschernutter, M; Schlichtenbrede, FC; Howe, S; Balaggan, KS; Munro, PM; Bainbridge, JW; Thrasher, AJ; Smith, AJ; Ali, RR Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy.
Gene Ther. 2005; 12(8): 694-701. [OPEN ACCESS]
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2003

Gattenlohner, S; Waller, C; Ertl, G; Bultmann, BD; Muller-Hermelink, HK; Marx, A NCAM(CD56) and RUNX1(AML1) are up-regulated in human ischemic cardiomyopathy and a rat model of chronic cardiac ischemia.
Am J Pathol. 2003; 163(3):1081-1090 [OPEN ACCESS]
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1997

Todisco, A; Takeuchi, Y; Urumov, A; Yamada, J; Stepan, VM; Yamada, T Molecular mechanisms for the growth factor action of gastrin.
Am J Physiol. 1997; 273(4 Pt 1):G891-G898 [OPEN ACCESS]
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Widschwendter, M; Daxenbichler, G; Culig, Z; Michel, S; Zeimet, AG; Mörtl, MG; Widschwendter, A; Marth, C Activity of retinoic acid receptor-gamma selectively binding retinoids alone and in combination with interferon-gamma in breast cancer cell lines.
Int J Cancer. 1997; 71(3):497-504
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1990

Scholz, H; Kohlwein, SD; Paltauf, F; Lezius, A; Spener, F Expression of a functionally active cardiac fatty acid-binding protein in the yeast, Saccharomyces cerevisiae.
Mol Cell Biochem. 1990; 98(1-2):69-74
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