Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: PHOSPHORYLATION - , . Treffer: 114

2018

Folci, A; Steinberger, A; Lee, B; Stanika, R; Scheruebel, S; Campiglio, M; Ramprecht, C; Pelzmann, B; Hell, JW; Obermair, GJ; Heine, M; Di Biase, V Molecular mimicking of C-terminal phosphorylation tunes the surface dynamics of CaV1.2 calcium channels in hippocampal neurons.
J Biol Chem. 2018; 293(3):1040-1053 [OPEN ACCESS]
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2017

Charoensin, S; Eroglu, E; Opelt, M; Bischof, H; Madreiter-Sokolowski, CT; Kirsch, A; Depaoli, MR; Frank, S; Schrammel, A; Mayer, B; Waldeck-Weiermair, M; Graier, WF; Malli, R Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS).
Free Radic Biol Med. 2017; 102(1):248-259 [OPEN ACCESS]
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Cuppens, T; Annibali, D; Coosemans, A; Trovik, J; Ter Haar, N; Colas, E; Garcia-Jimenez, A; Van de Vijver, K; Kruitwagen, RP; Brinkhuis, M; Zikan, M; Dundr, P; Huvila, J; Carpén, O; Haybaeck, J; Moinfar, F; Salvesen, HB; Stukan, M; Mestdagh, C; Zweemer, RP; Massuger, LF; Mallmann, MR; Wardelmann, E; Mints, M; Verbist, G; Thomas, D; Gommé, E; Hermans, E; Moerman, P; Bosse, T; Amant, F Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Clin Cancer Res. 2017; 23(5):1274-1285 [OPEN ACCESS]
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Nagaraj, C; Haitchi, HM; Heinemann, A; Howarth, PH; Olschewski, A; Marsh, LM Increased Expression of p22phox Mediates Airway Hyperresponsiveness in an Experimental Model of Asthma.
Antioxid Redox Signal. 2017; 27(18):1460-1472
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Parakaw, T; Suknuntha, K; Vivithanaporn, P; Schlagenhauf, A; Topanurak, S; Fucharoen, S; Pattanapanyasat, K; Schechter, A; Sibmooh, N; Srihirun, S Platelet inhibition and increased phosphorylated vasodilator-stimulated phosphoprotein following sodium nitrite inhalation.
Nitric Oxide. 2017; 66(6):10-16
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Peschel, I; Podmirseg, SR; Taschler, M; Duyster, J; Götze, KS; Sill, H; Nachbaur, D; Jäkel, H; Hengst, L FLT3 and FLT3-ITD phosphorylate and inactivate the cyclin-dependent kinase inhibitor p27Kip1 in acute myeloid leukemia.
Haematologica. 2017; 102(8):1378-1389 [OPEN ACCESS]
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Plastira, I; Bernhart, E; Goeritzer, M; DeVaney, T; Reicher, H; Hammer, A; Lohberger, B; Wintersperger, A; Zucol, B; Graier, WF; Kratky, D; Malle, E; Sattler, W Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
J Neuroinflammation. 2017; 14(1):253-253 [OPEN ACCESS]
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Windpassinger, C; Piard, J; Bonnard, C; Alfadhel, M; Lim, S; Bisteau, X; Blouin, S; Ali, NB; Ng, AYJ; Lu, H; Tohari, S; Talib, SZA; van Hul, N; Caldez, MJ; Van Maldergem, L; Yigit, G; Kayserili, H; Youssef, SA; Coppola, V; de Bruin, A; Tessarollo, L; Choi, H; Rupp, V; Roetzer, K; Roschger, P; Klaushofer, K; Altmüller, J; Roy, S; Venkatesh, B; Ganger, R; Grill, F; Ben Chehida, F; Wollnik, B; Altunoglu, U; Al Kaissi, A; Reversade, B; Kaldis, P CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
Am J Hum Genet. 2017; 101(3):391-403 [OPEN ACCESS]
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2016

Dernayka, L; Rauch, N; Jarboui, MA; Zebisch, A; Texier, Y; Horn, N; Romano, D; Gloeckner, CJ; Kriegsheim, Av; Ueffing, M; Kolch, W; Boldt, K Autophosphorylation on S614 inhibits the activity and the transforming potential of BRAF.
Cell Signal. 2016; 28(9):1432-1439
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Donnerer, J; Liebmann, I ERK1/2 Phosphorylation in the Rat Supraoptic Nucleus, Dorsal Raphe Nucleus, and Locus Coeruleus Neurons Following Noxious Stimulation to the Hind Paw.
Pharmacology. 2016; 97(1-2):57-62
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Koyani, CN; Kitz, K; Rossmann, C; Bernhart, E; Huber, E; Trummer, C; Windischhofer, W; Sattler, W; Malle, E Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death.
Biochem Pharmacol. 2016; 104:29-41 [OPEN ACCESS]
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Patriarchi, T; Qian, H; Di Biase, V; Malik, ZA; Chowdhury, D; Price, JL; Hammes, EA; Buonarati, OR; Westenbroek, RE; Catterall, WA; Hofmann, F; Xiang, YK; Murphy, GG; Chen, CY; Navedo, MF; Hell, JW Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor.
EMBO J. 2016; 35(12):1330-1345 [OPEN ACCESS]
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Verbrugge, SE; Al, M; Assaraf, YG; Kammerer, S; Chandrupatla, DM; Honeywell, R; Musters, RP; Giovannetti, E; O'Toole, T; Scheffer, GL; Krige, D; de Gruijl, TD; Niessen, HW; Lems, WF; Kramer, PA; Scheper, RJ; Cloos, J; Ossenkoppele, GJ; Peters, GJ; Jansen, G Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR.
Oncotarget. 2016; 7(5):5240-5257 [OPEN ACCESS]
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Vogl, F; Humpolickova, J; Amaro, M; Koller, D; Kofeler, H; Zenzmaier, E; Hof, M; Hermetter, A Role of protein kinase C delta in apoptotic signaling of oxidized phospholipids in RAW 264.7 macrophages
BBA-MOL CELL BIOL L. 2016; 1861(4): 320-330.
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2015

Crescenzo, R; Abate, F; Lasorsa, E; Tabbo', F; Gaudiano, M; Chiesa, N; Di Giacomo, F; Spaccarotella, E; Barbarossa, L; Ercole, E; Todaro, M; Boi, M; Acquaviva, A; Ficarra, E; Novero, D; Rinaldi, A; Tousseyn, T; Rosenwald, A; Kenner, L; Cerroni, L; Tzankov, A; Ponzoni, M; Paulli, M; Weisenburger, D; Chan, WC; Iqbal, J; Piris, MA; Zamo', A; Ciardullo, C; Rossi, D; Gaidano, G; Pileri, S; Tiacci, E; Falini, B; Shultz, LD; Mevellec, L; Vialard, JE; Piva, R; Bertoni, F; Rabadan, R; Inghirami, G; European T-Cell Lymphoma Study Group, T-Cell Project: Prospective Collection of Data in Patients with Peripheral T-Cell Lymphoma and the AIRC 5xMille Consortium “Genetics-Driven Targeted Management of Lymphoid Malignancies” Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.
Cancer Cell. 2015; 27(4):516-532 [OPEN ACCESS]
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Donnerer, J; Liebmann, I pERK1/2 immunofluorescence in rat dorsal horn and paraventricular nucleus neurons as a marker for sensitization and inhibition in the pain pathway.
Tissue Cell. 2015; 47(1):55-60
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González, A; Shimobayashi, M; Eisenberg, T; Merle, DA; Pendl, T; Hall, MN; Moustafa, T TORC1 promotes phosphorylation of ribosomal protein S6 via the AGC kinase Ypk3 in Saccharomyces cerevisiae.
PLoS One. 2015; 10(3):e0120250-e0120250 [OPEN ACCESS]
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Koentges, C; König, A; Pfeil, K; Hölscher, ME; Schnick, T; Wende, AR; Schrepper, A; Cimolai, MC; Kersting, S; Hoffmann, MM; Asal, J; Osterholt, M; Odening, KE; Doenst, T; Hein, L; Abel, ED; Bode, C; Bugger, H Myocardial mitochondrial dysfunction in mice lacking adiponectin receptor 1.
Basic Res Cardiol. 2015; 110(4): 37-37.
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Koentges, C; Pfeil, K; Schnick, T; Wiese, S; Dahlbock, R; Cimolai, MC; Meyer-Steenbuck, M; Cenkerova, K; Hoffmann, MM; Jaeger, C; Odening, KE; Kammerer, B; Hein, L; Bode, C; Bugger, H SIRT3 deficiency impairs mitochondrial and contractile function in the heart.
Basic Res Cardiol. 2015; 110(4): 36-36.
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Röhl, A; Tippel, F; Bender, E; Schmid, AB; Richter, K; Madl, T; Buchner, J Hop/Sti1 phosphorylation inhibits its co-chaperone function.
EMBO Rep. 2015; 16(2):240-249 [OPEN ACCESS]
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Scazzocchio, B; Varì, R; Filesi, C; Del Gaudio, I; D'Archivio, M; Santangelo, C; Iacovelli, A; Galvano, F; Pluchinotta, FR; Giovannini, C; Masella, R Protocatechuic acid activates key components of insulin signaling pathway mimicking insulin activity.
Mol Nutr Food Res. 2015; 59(8):1472-1481
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Schwarzl, M; Hamdani, N; Seiler, S; Alogna, A; Manninger, M; Reilly, S; Zirngast, B; Kirsch, A; Steendijk, P; Verderber, J; Zweiker, D; Eller, P; Höfler, G; Schauer, S; Eller, K; Maechler, H; Pieske, BM; Linke, WA; Casadei, B; Post, H A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction.
Am J Physiol Heart Circ Physiol. 2015; 309(9):H1407-H1418 [OPEN ACCESS]
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Sturm, EM; Parzmair, GP; Radnai, B; Frei, RB; Sturm, GJ; Hammer, A; Schuligoi, R; Lippe, IT; Heinemann, A Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils.
Eur J Immunol. 2015; 45(5):1548-1559 [OPEN ACCESS]
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2014

Arzt, L; Kothmaier, H; Halbwedl, I; Quehenberger, F; Popper, HH Signal transducer and activator of transcription 1 (STAT1) acts like an oncogene in malignant pleural mesothelioma.
Virchows Arch. 2014; 465(1):79-88
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Biasin, V; Chwalek, K; Wilhelm, J; Best, J; Marsh, LM; Ghanim, B; Klepetko, W; Fink, L; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.
Int J Biochem Cell Biol. 2014; 54(3):137-148
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Folci, A; Mapelli, L; Sassone, J; Prestori, F; D'Angelo, E; Bassani, S; Passafaro, M Loss of hnRNP K impairs synaptic plasticity in hippocampal neurons.
J Neurosci. 2014; 34(27): 9088-9095. [OPEN ACCESS]
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Haack, TB; Gorza, M; Danhauser, K; Mayr, JA; Haberberger, B; Wieland, T; Kremer, L; Strecker, V; Graf, E; Memari, Y; Ahting, U; Kopajtich, R; Wortmann, SB; Rodenburg, RJ; Kotzaeridou, U; Hoffmann, GF; Sperl, W; Wittig, I; Wilichowski, E; Schottmann, G; Schuelke, M; Plecko, B; Stephani, U; Strom, TM; Meitinger, T; Prokisch, H; Freisinger, P Phenotypic spectrum of eleven patients and five novel MTFMT mutations identified by exome sequencing and candidate gene screening.
Mol Genet Metab. 2014; 111(3): 342-352.
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Lichtenegger, M; Groschner, K TRPC3: a multifunctional signaling molecule.
Handb Exp Pharmacol. 2014; 222: 67-84.
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Seo, K; Rainer, PP; Shalkey Hahn, V; Lee, DI; Jo, SH; Andersen, A; Liu, T; Xu, X; Willette, RN; Lepore, JJ; Marino, JP; Birnbaumer, L; Schnackenberg, CG; Kass, DA Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.
Proc Natl Acad Sci U S A. 2014; 111(4):1551-1556 [OPEN ACCESS]
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Veith, C; Zakrzewicz, D; Dahal, BK; Bálint, Z; Murmann, K; Wygrecka, M; Seeger, W; Schermuly, RT; Weissmann, N; Kwapiszewska, G Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.
Thromb Haemost. 2014; 112(6):1288-1303
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Walther, S; Pluteanu, F; Renz, S; Nikonova, Y; Maxwell, JT; Yang, LZ; Schmidt, K; Edwards, JN; Wakula, P; Groschner, K; Maier, LS; Spiess, J; Blatter, LA; Pieske, B; Kockskämper, J Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177.
Am J Physiol Heart Circ Physiol. 2014; 307(5):H689-H700 [OPEN ACCESS]
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2013

Anderson, CD; Biffi, A; Nalls, MA; Devan, WJ; Schwab, K; Ayres, AM; Valant, V; Ross, OA; Rost, NS; Saxena, R; Viswanathan, A; Worrall, BB; Brott, TG; Goldstein, JN; Brown, D; Broderick, JP; Norrving, B; Greenberg, SM; Silliman, SL; Hansen, BM; Tirschwell, DL; Lindgren, A; Slowik, A; Schmidt, R; Selim, M; Roquer, J; Montaner, J; Singleton, AB; Kidwell, CS; Woo, D; Furie, KL; Meschia, JF; Rosand, J; on behalf of the International Stroke Genetics Consortium Common Variants Within Oxidative Phosphorylation Genes Influence Risk of Ischemic Stroke and Intracerebral Hemorrhage.
Stroke. 2013; 44(3):612-619 [OPEN ACCESS]
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Bhandari, D; Zhang, J; Menon, S; Lord, C; Chen, S; Helm, JR; Thorsen, K; Corbett, KD; Hay, JC; Ferro-Novick, S Sit4p/PP6 regulates ER-to-Golgi traffic by controlling the dephosphorylation of COPII coat subunits.
Mol Biol Cell. 2013; 24(17):2727-2738 [OPEN ACCESS]
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Büttner, S; Faes, L; Reichelt, WN; Broeskamp, F; Habernig, L; Benke, S; Kourtis, N; Ruli, D; Carmona-Gutierrez, D; Eisenberg, T; D'hooge, P; Ghillebert, R; Franssens, V; Harger, A; Pieber, TR; Freudenberger, P; Kroemer, G; Sigrist, SJ; Winderickx, J; Callewaert, G; Tavernarakis, N; Madeo, F The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models.
Cell Death Differ. 2013; 20(3):465-477 [OPEN ACCESS]
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Carmona-Gutierrez, D; Alavian-Ghavanini, A; Habernig, L; Bauer, MA; Hammer, A; Rossmann, C; Zimmermann, AS; Ruckenstuhl, C; Büttner, S; Eisenberg, T; Sattler, W; Malle, E; Madeo, F The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast.
Cell Cycle. 2013; 12(11):1704-1712 [OPEN ACCESS]
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Doddapattar, P; Radović, B; Patankar, JV; Obrowsky, S; Jandl, K; Nusshold, C; Kolb, D; Vujić, N; Doshi, L; Chandak, PG; Goeritzer, M; Ahammer, H; Hoefler, G; Sattler, W; Kratky, D Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice.
Mol Nutr Food Res. 2013; 57(10):1718-1728 [OPEN ACCESS]
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Friedmacher, F; Gosemann, JH; Takahashi, H; Corcionivoschi, N; Puri, P Decreased pulmonary c-Cbl expression and tyrosine phosphorylation in the nitrofen-induced rat model of congenital diaphragmatic hernia.
Pediatr Surg Int. 2013; 29(1): 19-24.
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Giovinazzo, F; Schimmack, S; Svejda, B; Alaimo, D; Pfragner, R; Modlin, I; Kidd, M Chromogranin A and its fragments as regulators of small intestinal neuroendocrine neoplasm proliferation.
PLoS One. 2013; 8(11):e81111-e81111 [OPEN ACCESS]
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Jakus, PB; Kalman, N; Antus, C; Radnai, B; Tucsek, Z; Gallyas, F; Sumegi, B; Veres, B TRAF6 is functional in inhibition of TLR4-mediated NF-κB activation by resveratrol.
J Nutr Biochem. 2013; 24(5):819-823
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Kockskamper, A; von Lewinski, D; Zhu, D; Kockskamper, J; Khafaga, M; Schmidt, AG; Post, H; Pieske, B Relevance of stretch-induced phosphorylation of MAPK and p90rsk in human myocardium.
Front Biosci (Elite Ed). 2013; 5(6):883-892
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König, S; Browne, S; Doleschal, B; Schernthaner, M; Poteser, M; Mächler, H; Wittchow, E; Braune, M; Muik, M; Romanin, C; Groschner, K Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle.
Am J Physiol Heart Circ Physiol. 2013; 305(11):H1646-H1657 [OPEN ACCESS]
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Lassance, L; Miedl, H; Absenger, M; Diaz-Perez, F; Lang, U; Desoye, G; Hiden, U Hyperinsulinemia stimulates angiogenesis of human fetoplacental endothelial cells: a possible role of insulin in placental hypervascularization in diabetes mellitus.
J Clin Endocrinol Metab. 2013; 98(9):E1438-E1447 [OPEN ACCESS]
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Matsuo, Y; Oberbach, A; Till, H; Inge, TH; Wabitsch, M; Moss, A; Jehmlich, N; Völker, U; Müller, U; Siegfried, W; Kanesawa, N; Kurabayashi, M; Schuler, G; Linke, A; Adams, V Impaired HDL function in obese adolescents: impact of lifestyle intervention and bariatric surgery.
Obesity (Silver Spring). 2013; 21(12):E687-E695 [OPEN ACCESS]
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Moldvay, J; Barbai, T; Bogos, K; Piurko, V; Fillinger, J; Popper, HH; Tímár, J EGFR autophosphorylation but not protein score correlates with histologic and molecular subtypes in lung adenocarcinoma.
Diagn Mol Pathol. 2013; 22(4):204-209
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Pozo, K; Castro-Rivera, E; Tan, C; Plattner, F; Schwach, G; Siegl, V; Meyer, D; Guo, A; Gundara, J; Mettlach, G; Richer, E; Guevara, JA; Ning, L; Gupta, A; Hao, G; Tsai, LH; Sun, X; Antich, P; Sidhu, S; Robinson, BG; Chen, H; Nwariaku, FE; Pfragner, R; Richardson, JA; Bibb, JA The role of Cdk5 in neuroendocrine thyroid cancer.
Cancer Cell. 2013; 24(4):499-511 [OPEN ACCESS]
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Riehle, C; Wende, AR; Sena, S; Pires, KM; Pereira, RO; Zhu, Y; Bugger, H; Frank, D; Bevins, J; Chen, D; Perry, CN; Dong, XC; Valdez, S; Rech, M; Sheng, X; Weimer, BC; Gottlieb, RA; White, MF; Abel, ED Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
J Clin Invest. 2013; 123(12): 5319-5333. [OPEN ACCESS]
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Rungatscher, A; Hallström, S; Giacomazzi, A; Linardi, D; Milani, E; Tessari, M; Luciani, GB; Scarabelli, TM; Mazzucco, A; Faggian, G Role of calcium desensitization in the treatment of myocardial dysfunction after deep hypothermic circulatory arrest.
Crit Care. 2013; 17(5):R245-R245 [OPEN ACCESS]
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Sivakumaran, V; Stanley, BA; Tocchetti, CG; Ballin, JD; Caceres, V; Zhou, L; Keceli, G; Rainer, PP; Lee, DI; Huke, S; Ziolo, MT; Kranias, EG; Toscano, JP; Wilson, GM; O'Rourke, B; Kass, DA; Mahaney, JE; Paolocci, N HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Antioxid Redox Signal. 2013; 19(11):1185-1197 [OPEN ACCESS]
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Stradner, MH; Gruber, G; Angerer, H; Huber, V; Setznagl, D; Kremser, ML; Moazedi-Fürst, FC; Windhager, R; Graninger, WB Sphingosine 1-phosphate counteracts the effects of interleukin-1β in human chondrocytes.
Arthritis Rheum. 2013; 65(8):2113-2122 [OPEN ACCESS]
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Treiber, F; Rosker, C; Keren-Raifman, T; Steinecker, B; Gorischek, A; Dascal, N; Schreibmayer, W Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase.
Biochim Biophys Acta. 2013; 1828(4):1214-1221 [OPEN ACCESS]
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