Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: PHOSPHATIDYLINOSITOL 3-KINASES - METABOLISM , . Treffer: 26

2022

Abdellatif, M; Trummer-Herbst, V; Heberle, AM; Humnig, A; Pendl, T; Durand, S; Cerrato, G; Hofer, SJ; Islam, M; Voglhuber, J; Ramos, Pittol, JM; Kepp, O; Hoefler, G; Schmidt, A; Rainer, PP; Scherr, D; von, Lewinski, D; Bisping, E; McMullen, JR; Diwan, A; Eisenberg, T; Madeo, F; Thedieck, K; Kroemer, G; Sedej, S Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity.
Circulation. 2022; 145(25):1853-1866 Doi: 10.1161/CIRCULATIONAHA.122.059863 [OPEN ACCESS]
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Rüschoff, JH; Haberecker, M; Tsourti, Z; Nackaerts, K; de, Perrot, M; Brcic, L; Nadal, E; Tsimpoukis, S; Gray, SG; Ampollini, L; Aerts, JG; Felley-Bosco, E; Kirschner, MB; Monkhorst, K; Weynand, B; Bavaghar-Zaeimi, F; Samarzija, M; Llatjos, R; Finn, SP; Silini, E; von, der, Thüsen, J; Marti, N; Vervita, K; Kammler, R; Peters, S; Stahel, RA; Baas, P; Opitz, I, , ETOP, Mesoscape, consortium Expression of phosphorylated ribosomal protein S6 in mesothelioma patients - correlation with clinico-pathological characteristics and outcome: results from the European Thoracic Oncology Platform (ETOP) Mesoscape project.
Mod Pathol. 2022; 35(12):1888-1899 Doi: 10.1038/s41379-022-01145-0 [OPEN ACCESS]
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2020

Golob-Schwarzl, N; Puchas, P; Gogg-Kamerer, M; Weichert, W; Göppert, B; Haybaeck, J New Pancreatic Cancer Biomarkers eIF1, eIF2D, eIF3C and eIF6 Play a Major Role in Translational Control in Ductal Adenocarcinoma.
Anticancer Res. 2020; 40(6):3109-3118 Doi: 10.21873/anticanres.14292 [OPEN ACCESS]
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2017

Golob-Schwarzl, N; Krassnig, S; Toeglhofer, AM; Park, YN; Gogg-Kamerer, M; Vierlinger, K; Schröder, F; Rhee, H; Schicho, R; Fickert, P; Haybaeck, J New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors.
Eur J Cancer. 2017; 83(60):56-70 Doi: 10.1016/j.ejca.2017.06.003
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2016

Kaushik, AK; Shojaie, A; Panzitt, K; Sonavane, R; Venghatakrishnan, H; Manikkam, M; Zaslavsky, A; Putluri, V; Vasu, VT; Zhang, Y; Khan, AS; Lloyd, S; Szafran, AT; Dasgupta, S; Bader, DA; Stossi, F; Li, H; Samanta, S; Cao, X; Tsouko, E; Huang, S; Frigo, DE; Chan, L; Edwards, DP; Kaipparettu, BA; Mitsiades, N; Weigel, NL; Mancini, M; McGuire, SE; Mehra, R; Ittmann, MM; Chinnaiyan, AM; Putluri, N; Palapattu, GS; Michailidis, G; Sreekumar, A Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer.
Nat Commun. 2016; 7(7):11612-11612 Doi: 10.1038/ncomms11612 [OPEN ACCESS]
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2015

Sturm, EM; Parzmair, GP; Radnai, B; Frei, RB; Sturm, GJ; Hammer, A; Schuligoi, R; Lippe, IT; Heinemann, A Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils.
Eur J Immunol. 2015; 45(5):1548-1559 Doi: 10.1002/eji.201445196 [OPEN ACCESS]
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Zakharova, IO; Sokolova, TV; Akhmetshina, AO; Avrova, NF Role of Protein Kinase Akt Activation in Protective Effect of Ganglioside GM1 on PC12 Cells Exposed to H2O2.
Bull Exp Biol Med. 2015; 159(5): 610-613. Doi: 10.1007/s10517-015-3026-2
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2014

Bálint, Z; Zabini, D; Konya, V; Nagaraj, C; Végh, AG; Váró, G; Wilhelm, I; Fazakas, C; Krizbai, IA; Heinemann, A; Olschewski, H; Olschewski, A Double-stranded RNA attenuates the barrier function of human pulmonary artery endothelial cells.
PLoS One. 2014; 8(6):e63776-e63776 Doi: 10.1371/journal.pone.0063776 [OPEN ACCESS]
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Dengler, MA; Weilbacher, A; Gutekunst, M; Staiger, AM; Vöhringer, MC; Horn, H; Ott, G; Aulitzky, WE; van der Kuip, H Discrepant NOXA (PMAIP1) transcript and NOXA protein levels: a potential Achilles' heel in mantle cell lymphoma.
Cell Death Dis. 2014; 5(8):e1013-e1013 Doi: 10.1038/cddis.2013.552 [OPEN ACCESS]
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Miething, C; Scuoppo, C; Bosbach, B; Appelmann, I; Nakitandwe, J; Ma, J; Wu, G; Lintault, L; Auer, M; Premsrirut, PK; Teruya-Feldstein, J; Hicks, J; Benveniste, H; Speicher, MR; Downing, JR; Lowe, SW PTEN action in leukaemia dictated by the tissue microenvironment.
Nature. 2014; 510(7505):402-406 Doi: 10.1038/nature13239 [OPEN ACCESS]
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Quan, P; Moinfar, F; Kufferath, I; Absenger, M; Kueznik, T; Denk, H; Zatloukal, K; Haybaeck, J Effects of targeting endometrial stromal sarcoma cells via histone deacetylase and PI3K/AKT/mTOR signaling.
Anticancer Res. 2014; 34(6):2883-2897
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2013

Fock, V; Mairhofer, M; Otti, GR; Hiden, U; Spittler, A; Zeisler, H; Fiala, C; Knöfler, M; Pollheimer, J Macrophage-derived IL-33 is a critical factor for placental growth.
J Immunol. 2013; 191(7):3734-3743 Doi: 10.4049/jimmunol.1300490 [OPEN ACCESS]
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2012

Hafner, C; Houben, R; Baeurle, A; Ritter, C; Schrama, D; Landthaler, M; Becker, JC Activation of the PI3K/AKT pathway in Merkel cell carcinoma.
PLoS One. 2012; 7(2):e31255-e31255 Doi: 10.1371/journal.pone.0031255 [OPEN ACCESS]
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Khan, MJ; Alam, MR; Waldeck-Weiermair, M; Karsten, F; Groschner, L; Riederer, M; Hallstroem, S; Rockenfeller, P; Konya, V; Heinemann, A; Madeo, F; Graier, WF; Malli, R Inhibition of autophagy rescues palmitic acid induced necroptosis of endothelial cells.
J Biol Chem. 2012; 287(25):21110-21120 Doi: 10.1074/jbc.M111.319129 [OPEN ACCESS]
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Wygrecka, M; Zakrzewicz, D; Taborski, B; Didiasova, M; Kwapiszewska, G; Preissner, KT; Markart, P TGF-β1 induces tissue factor expression in human lung fibroblasts in a PI3K/JNK/Akt-dependent and AP-1-dependent manner.
Am J Respir Cell Mol Biol. 2012; 47(5):614-627 Doi: 10.1165/rcmb.2012-0097OC
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2011

Erttmann, SF; Bast, A; Seidel, J; Breitbach, K; Walther, R; Steinmetz, I PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2.
Free Radic Biol Med. 2011; 51(3):626-640 Doi: 10.1016/j.freeradbiomed.2011.05.022
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Luschnig-Schratl, P; Sturm, EM; Konya, V; Philipose, S; Marsche, G; Fröhlich, E; Samberger, C; Lang-Loidolt, D; Gattenlöhner, S; Lippe, IT; Peskar, BA; Schuligoi, R; Heinemann, A EP4 receptor stimulation down-regulates human eosinophil function.
Cell Mol Life Sci. 2011; 68(21): 3573-3587. Doi: 10.1007/s00018-011-0642-5 [OPEN ACCESS]
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Mantoni, TS; Lunardi, S; Al-Assar, O; Masamune, A; Brunner, TB Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling.
Cancer Res. 2011; 71(10):3453-8 Doi: 10.1158/0008-5472.CAN-10-1633 [OPEN ACCESS]
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2010

von Lewinski, D; Rainer, PP; Gasser, R; Huber, MS; Khafaga, M; Wilhelm, B; Haas, T; Mächler, H; Rössl, U; Pieske, B Glucose-transporter-mediated positive inotropic effects in human myocardium of diabetic and nondiabetic patients.
Metabolism. 2010; 59(7):1020-1028 Doi: 10.1016/j.metabol.2009.10.025
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2009

Colomiere, M; Permezel, M; Riley, C; Desoye, G; Lappas, M Defective insulin signaling in placenta from pregnancies complicated by gestational diabetes mellitus.
Eur J Endocrinol. 2009; 160(4):567-578 Doi: 10.1530/EJE-09-0031 [OPEN ACCESS]
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2008

Bernhard, EJ; Brunner, TB Progress towards the use of HIV protease inhibitors in cancer therapy.
Cancer Biol Ther. 2008; 7(5):636-7 Doi: 10.4161/cbt.7.5.6087
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2006

Isoda, K; Young, JL; Zirlik, A; MacFarlane, LA; Tsuboi, N; Gerdes, N; Schönbeck, U; Libby, P Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.
ARTERIOSCL THROM VAS. 2006; 26(3): 611-617. Doi: 10.1161/01.ATV.0000201938.78044.75 [OPEN ACCESS]
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2005

Andres, RH; Ducray, AD; Huber, AW; Pérez-Bouza, A; Krebs, SH; Schlattner, U; Seiler, RW; Wallimann, T; Widmer, HR Effects of creatine treatment on survival and differentiation of GABA-ergic neurons in cultured striatal tissue.
J Neurochem. 2005; 95(1):33-45 Doi: 10.1111/j.1471-4159.2005.03337.x
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Rust, C; Bauchmuller, K; Fickert, P; Fuchsbichler, A; Beuers, U Phosphatidylinositol 3-kinase-dependent signaling modulates taurochenodeoxycholic acid-induced liver injury and cholestasis in perfused rat livers.
AMER J PHYSIOL-GASTROINTEST L. 2005; 289(1): G88-G94. Doi: 10.1152/ajpgi.00450.2004 [OPEN ACCESS]
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Stepan, V; Ramamoorthy, S; Nitsche, H; Zavros, Y; Merchant, JL; Todisco, A Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells.
J Biol Chem. 2005; 280(16):15700-15708 Doi: 10.1074/jbc.M413037200 [OPEN ACCESS]
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2004

Veres, B; Radnai, B; Gallyas, F; Varbiro, G; Berente, Z; Osz, E; Sumegi, B Regulation of kinase cascades and transcription factors by a poly(ADP-ribose) polymerase-1 inhibitor, 4-hydroxyquinazoline, in lipopolysaccharide-induced inflammation in mice.
J Pharmacol Exp Ther. 2004; 310(1): 247-255. Doi: 10.1124/jpet.104.065151
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