Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: PHARMACOKINETICS, . Treffer: 108

2018

Basu, A; Pieber, TR; Hansen, AK; Sach-Friedl, S; Erichsen, L; Basu, R; Haahr, H Greater early postprandial suppression of endogenous glucose production and higher initial glucose disappearance is achieved with fast-acting insulin aspart compared with insulin aspart.
Diabetes Obes Metab. 2018; 20(7):1615-1622 [OPEN ACCESS]
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Haahr, H; Pieber, TR; Mathieu, C; Gondolf, T; Shiramoto, M; Erichsen, L; Heise, T Clinical Pharmacology of Fast-Acting Insulin Aspart Versus Insulin Aspart Measured as Free or Total Insulin Aspart and the Relation to Anti-Insulin Aspart Antibody Levels in Subjects with Type 1 Diabetes Mellitus.
Clin Pharmacokinet. 2018;
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Högenauer, C; Mahida, Y; Stallmach, A; Marteau, P; Rydzewska, G; Ivashkin, V; Gargalianos-Kakolyris, P; Michon, I; Adomakoh, N; Georgopali, A; Tretter, R; Karas, A; Reinisch, W Pharmacokinetics and safety of fidaxomicin in patients with inflammatory bowel disease and Clostridium difficile infection: an open-label Phase IIIb/IV study (PROFILE).
J Antimicrob Chemother. 2018; 73(12):3430-3441
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Welte, R; Eller, P; Lorenz, I; Joannidis, M; Bellmann, R Anidulafungin pharmacokinetics in ascites and pleural effusion of critically ill patients.
Antimicrob Agents Chemother. 2018; [OPEN ACCESS]
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2017

Baker, D; Pryce, G; Visintin, C; Sisay, S; Bondarenko, AI; Vanessa Ho, WS; Jackson, SJ; Williams, TE; Al-Izki, S; Sevastou, I; Okuyama, M; Graier, WF; Stevenson, LA; Tanner, C; Ross, R; Pertwee, RG; Henstridge, CM; Irving, AJ; Schulman, J; Powell, K; Baker, MD; Giovannoni, G; Selwood, DL Big conductance calcium-activated potassium channel openers control spasticity without sedation.
Br J Pharmacol. 2017; 174(16):2662-2681 [OPEN ACCESS]
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Gessler, T; Ghofrani, HA; Held, M; Klose, H; Leuchte, H; Olschewski, H; Rosenkranz, S; Fels, L; Li, N; Ren, D; Kaiser, A; Schultze-Mosgau, MH; Müllinger, B; Rohde, B; Seeger, W The safety and pharmacokinetics of rapid iloprost aerosol delivery via the BREELIB nebulizer in pulmonary arterial hypertension.
Pulm Circ. 2017; 7(2):505-513 [OPEN ACCESS]
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Hauzenberger, JR; Hipszer, BR; Loeum, C; McCue, PA; DeStefano, M; Torjman, MC; Kaner, MT; Dinesen, AR; Chervoneva, I; Pieber, TR; Joseph, JI Detailed Analysis of Insulin Absorption Variability and the Tissue Response to Continuous Subcutaneous Insulin Infusion Catheter Implantation in Swine.
Diabetes Technol Ther. 2017; 19(11):641-650 [OPEN ACCESS]
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Schwingenschuh, S; Scharfetter, H; Martinsen, ØG; Boulgaropoulos, B; Augustin, T; Tiffner, KI; Dragatin, C; Raml, R; Hoefferer, C; Prandl, EC; Sinner, F; Hajnsek, M Assessment of skin permeability to topically applied drugs by skin impedance and admittance.
Physiol Meas. 2017; 38(11):N138-N150
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2016

Bodenlenz, M; Dragatin, C; Liebenberger, L; Tschapeller, B; Boulgaropoulos, B; Augustin, T; Raml, R; Gatschelhofer, C; Wagner, N; Benkali, K; Rony, F; Pieber, T; Sinner, F Kinetics of Clobetasol-17-Propionate in Psoriatic Lesional and Non-Lesional Skin Assessed by Dermal Open Flow Microperfusion with Time and Space Resolution.
Pharm Res. 2016; 33(9):2229-2238 [OPEN ACCESS]
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Brownbill, P; Chernyavsky, I; Bottalico, B; Desoye, G; Hansson, S; Kenna, G; Knudsen, LE; Markert, UR; Powles-Glover, N; Schneider, H; Leach, L An international network (PlaNet) to evaluate a human placental testing platform for chemicals safety testing in pregnancy.
Reprod Toxicol. 2016; 64(5):191-202
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Dragatin, C; Polus, F; Bodenlenz, M; Calonder, C; Aigner, B; Tiffner, KI; Mader, JK; Ratzer, M; Woessner, R; Pieber, TR; Cheng, Y; Loesche, C; Sinner, F; Bruin, G Secukinumab distributes into dermal interstitial fluid of psoriasis patients as demonstrated by open flow microperfusion.
Exp Dermatol. 2016; 25(2):157-159 [OPEN ACCESS]
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Fröhlich, E; Mercuri, A; Wu, S; Salar-Behzadi, S Measurements of Deposition, Lung Surface Area and Lung Fluid for Simulation of Inhaled Compounds.
Front Pharmacol. 2016; 7(7):181-181 [OPEN ACCESS]
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Heise, T; Korsatko, S; Nosek, L; Coester, HV; Deller, S; Roepstorff, C; Segel, S; Kapur, R; Haahr, H; Hompesch, M Steady state is reached within 2-3 days of once-daily administration of degludec, a basal insulin with an ultralong duration of action.
J Diabetes. 2016; 8(1):132-138
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Klamroth, R; Simpson, M; von Depka-Prondzinski, M; Gill, JC; Morfini, M; Powell, JS; Santagostino, E; Davis, J; Huth-Kühne, A; Leissinger, C; Neumeister, P; Bensen-Kennedy, D; Feussner, A; Limsakun, T; Zhou, M; Veldman, A; St Ledger, K; Blackman, N; Pabinger, I Comparative pharmacokinetics of rVIII-SingleChain and octocog alfa (Advate(®) ) in patients with severe haemophilia A.
Haemophilia. 2016; 22(5):730-738 [OPEN ACCESS]
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Mader, JK; Jensen, L; Ingwersen, SH; Christiansen, E; Heller, S; Pieber, TR Pharmacokinetic Properties of Liraglutide as Adjunct to Insulin in Subjects with Type 1 Diabetes Mellitus.
Clin Pharmacokinet. 2016; 55(11):1457-1463 [OPEN ACCESS]
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Schaller, S; Lippert, J; Schaupp, L; Pieber, TR; Schuppert, A; Eissing, T Robust PBPK/PD-Based Model Predictive Control of Blood Glucose.
IEEE Trans Biomed Eng. 2016; 63(7):1492-1504 [OPEN ACCESS]
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2015

Bodenlenz, M; Ellmerer, M; Schaupp, L; Jacobsen, LV; Plank, J; Brunner, GA; Wutte, A; Aigner, B; Mautner, SI; Pieber, TR Bioavailability of insulin detemir and human insulin at the level of peripheral interstitial fluid in humans, assessed by open-flow microperfusion.
Diabetes Obes Metab. 2015; 17(12):1166-1172
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Höfferer, C; Tutkur, D; Fledelius, C; Brand, CL; Alsted, TJ; Damgaard, J; Nishimura, E; Jeppesen, CB; Mautner, SI; Pieber, TR; Sinner, F Open flow microperfusion: pharmacokinetics of human insulin and insulin detemir in the interstitial fluid of subcutaneous adipose tissue.
Diabetes Obes Metab. 2015; 17(2):121-127
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Kepa, S; Horvath, B; Reitter-Pfoertner, S; Schemper, M; Quehenberger, P; Grundbichler, M; Heistinger, M; Neumeister, P; Mannhalter, C; Pabinger, I Parameters influencing FVIII pharmacokinetics in patients with severe and moderate haemophilia A.
Haemophilia. 2015; 21(3):343-350
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Wruss, J; Lanzerstorfer, P; Huemer, S; Himmelsbach, M; Mangge, H; Höglinger, O; Weghuber, D; Weghuber, J Differences in pharmacokinetics of apple polyphenols after standardized oral consumption of unprocessed apple juice.
Nutr J. 2015; 14(5):32-32 [OPEN ACCESS]
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2014

Jaksch, W; Messerer, B; Keck, B; Lischka, A; Urlesberger, B; Österreichischen Gesellschaft für Anästhesiologie, Reanimation und Intensivmedizin (ÖGARI) [Pharmacodynamic and pharmacokinetic characteristics of pain therapy in neonates: Austrian interdisciplinary recommendations on pediatric perioperative pain management].
Schmerz. 2014; 28(1):25-30
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Kvaternik, H; Wanek, T; Hammerschmidt, F; Zolle, I; Aigner, R; Kuntner, C Radiosynthesis of [124I]iodometomidate and biological evaluation using small-animal PET.
Mol Imaging Biol. 2014; 16(3):317-321
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Pieske, B; Butler, J; Filippatos, G; Lam, C; Maggioni, AP; Ponikowski, P; Shah, S; Solomon, S; Kraigher-Krainer, E; Samano, ET; Scalise, AV; Müller, K; Roessig, L; Gheorghiade, M; SOCRATES Investigators and Coordinators Rationale and design of the SOluble guanylate Cyclase stimulatoR in heArT failurE Studies (SOCRATES).
Eur J Heart Fail. 2014; 16(9):1026-1038 [OPEN ACCESS]
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Schweighofer, N; Lerchbaum, E; Trummer, O; Schwetz, V; Pieber, T; Obermayer-Pietsch, B Metformin resistance alleles in polycystic ovary syndrome: pattern and association with glucose metabolism.
Pharmacogenomics. 2014; 15(3):305-317
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2013

Birngruber, T; Ghosh, A; Perez-Yarza, V; Kroath, T; Ratzer, M; Pieber, TR; Sinner, F Cerebral open flow microperfusion: a new in vivo technique for continuous measurement of substance transport across the intact blood-brain barrier.
Clin Exp Pharmacol Physiol. 2013; 40(12):864-871
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Bodenlenz, M; Aigner, B; Dragatin, C; Liebenberger, L; Zahiragic, S; Höfferer, C; Birngruber, T; Priedl, J; Feichtner, F; Schaupp, L; Korsatko, S; Ratzer, M; Magnes, C; Pieber, TR; Sinner, F Clinical applicability of dOFM devices for dermal sampling.
Skin Res Technol. 2013; 19(4):474-483
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Dahaba, AA; Suljevic, I; Oettl, K; Xiao, Z; Dong, H; Xiong, L; Reibnegger, G Influence of acute normovolemic hemodilution on the pharmacokinetics of Cisatracurium Besylate.
Minerva Anestesiol. 2013; 79(11):1238-1247
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Huber, K; Connolly, SJ; Kher, A; Christory, F; Dan, GA; Hatala, R; Kiss, RG; Meier, B; Merkely, B; Pieske, B; Potpara, T; Stępińska, J; Klun, NV; Vinereanu, D; Widimský, P Practical use of dabigatran etexilate for stroke prevention in atrial fibrillation.
Int J Clin Pract. 2013; 67(6):516-526 [OPEN ACCESS]
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Mader, JK; Birngruber, T; Korsatko, S; Deller, S; Köhler, G; Boysen, S; Augustin, T; Mautner, SI; Sinner, F; Pieber, TR; AP@home Consortium Enhanced absorption of insulin aspart as the result of a dispersed injection strategy tested in a randomized trial in type 1 diabetic patients.
Diabetes Care. 2013; 36(4):780-785 [OPEN ACCESS]
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Strenger, V; Hofer, N; Rödl, S; Hönigl, M; Raggam, R; Seidel, MG; Dornbusch, HJ; Sperl, D; Lackner, H; Schwinger, W; Sovinz, P; Benesch, M; Urlesberger, B; Urban, C Age- and gender-related differences in teicoplanin levels in paediatric patients.
J Antimicrob Chemother. 2013; 68(10):2318-2323 [OPEN ACCESS]
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Verheyen, N; Pilz, S; Eller, K; Kienreich, K; Fahrleitner-Pammer, A; Pieske, B; Ritz, E; Tomaschitz, A Cinacalcet hydrochloride for the treatment of hyperparathyroidism.
Expert Opin Pharmacother. 2013; 14(6):793-806
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2012

Bodenlenz, M; Höfferer, C; Magnes, C; Schaller-Ammann, R; Schaupp, L; Feichtner, F; Ratzer, M; Pickl, K; Sinner, F; Wutte, A; Korsatko, S; Köhler, G; Legat, FJ; Benfeldt, EM; Wright, AM; Neddermann, D; Jung, T; Pieber, TR Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling.
Eur J Pharm Biopharm. 2012; 81(3):635-641
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Burian, B; Ortner, A; Prassl, R; Zimmer, A; Mosgoeller, W Clinical potential of VIP by modified pharmaco-kinetics and delivery mechanisms.
Endocr Metab Immune Disord Drug Targets. 2012; 12(4):344-350
PubMed

 

Helbok, A; Rangger, C; von Guggenberg, E; Saba-Lepek, M; Radolf, T; Thurner, G; Andreae, F; Prassl, R; Decristoforo, C Targeting properties of peptide-modified radiolabeled liposomal nanoparticles
NANOMED-NANOTECHNOL. 2012; 8(1): 112-118.
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2011

Dittrich, P; Beubler, E; Haltmeyer, K; Zimmer, A; Roblegg, E Pharmacokinetics of a novel liquid controlled release codeine formulation.
Drug Dev Ind Pharm. 2011; 37(9):1119-1124
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Donnarumma, F; Greilberger, J; Matzi, V; Lindenmann, J; Maier, A; Leis, HJ; Wintersteiger, R Pharmacokinetic evaluation of a novel anti-cancer drug
INT J CLIN PHARM. 2011; 33(2):320-320.
Web of Science

 

Ginter-Hanselmayer, G; Seebacher, C Treatment of tinea capitis - a critical appraisal.
J Dtsch Dermatol Ges. 2011; 9(2): 109-114. [OPEN ACCESS]
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Kuntner, C; Wanek, T; Hoffer, M; Dangl, D; Hornof, M; Kvaternik, H; Langer, O Radiosynthesis and assessment of ocular pharmacokinetics of (124)I-labeled chitosan in rabbits using small-animal PET.
Mol Imaging Biol. 2011; 13(2):222-226
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Traunmüller, F; Popovic, M; Konz, KH; Smolle-Jüttner, FM; Joukhadar, C Efficacy and safety of current drug therapies for invasive aspergillosis.
Pharmacology. 2011; 88(3-4): 213-224. [OPEN ACCESS]
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2010

Helbok, A; Decristoforo, C; Dobrozemsky, G; Rangger, C; Diederen, E; Stark, B; Prassl, R; von Guggenberg, E Radiolabeling of lipid-based nanoparticles for diagnostics and therapeutic applications: a comparison using different radiometals
J LIPOSOME RES. 2010; 20(3): 219-227.
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Kocher, S; Müller, W; Resch, B Linezolid treatment of nosocomial bacterial infection with multiresistant Gram-positive pathogens in preterm infants: a systematic review.
Int J Antimicrob Agents. 2010; 36(2): 106-110.
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Morgan, RE; Trauner, M; van Staden, CJ; Lee, PH; Ramachandran, B; Eschenberg, M; Afshari, CA; Qualls, CW; Lightfoot-Dunn, R; Hamadeh, HK Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Toxicol Sci. 2010; 118(2):485-500 [OPEN ACCESS]
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Petersen, AH; Korsatko, S; Kohler, G; Wutte, A; Olschewski, H; Sparre, T; Rastam, J; Wollmer, P; Pieber, TR The effect of terbutaline on the absorption of pulmonary administered insulin in subjects with asthma
BRIT J CLIN PHARMACOL. 2010; 69(3): 271-278. [OPEN ACCESS]
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Satterwhite, J; Heathman, M; Miller, PD; Marín, F; Glass, EV; Dobnig, H Pharmacokinetics of teriparatide (rhPTH[1-34]) and calcium pharmacodynamics in postmenopausal women with osteoporosis.
Calcif Tissue Int. 2010; 87(6):485-492 [OPEN ACCESS]
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Traunmüller, F; Schintler, MV; Metzler, J; Spendel, S; Mauric, O; Popovic, M; Konz, KH; Scharnagl, E; Joukhadar, C Soft tissue and bone penetration abilities of daptomycin in diabetic patients with bacterial foot infections.
J Antimicrob Chemother. 2010; 65(6): 1252-1257. [OPEN ACCESS]
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Traunmuller, F; Schintler, MV; Spendel, S; Popovic, M; Mauric, O; Scharnagl, E; Joukhadar, C Linezolid concentrations in infected soft tissue and bone following repetitive doses in diabetic patients with bacterial foot infections
INT J ANTIMICROBIAL AGENTS. 2010; 36(1): 84-86.
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Woelkart, K; Feizlmayr, E; Dittrich, P; Beubler, E; Pinl, F; Suter, A; Bauer, R Pharmacokinetics of Bilobalide, Ginkgolide A and B after Administration of Three Different Ginkgo biloba L. Preparations in Humans
PHYTOTHER RES. 2010; 24(3): 445-450.
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2009

Doshi, LS; Brahma, MK; Sayyed, SG; Dixit, AV; Chandak, PG; Pamidiboina, V; Motiwala, HF; Sharma, SD; Nemmani, KV Acute administration of GPR40 receptor agonist potentiates glucose-stimulated insulin secretion in vivo in the rat.
Metabolism. 2009; 58(3): 333-343.
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Klein, K; Kullak-Ublick, GA; Wagner, M; Trauner, M; Eloranta, JJ Hepatocyte nuclear factor-4alpha and bile acids regulate human concentrative nucleoside transporter-1 gene expression.
Am J Physiol Gastrointest Liver Physiol. 2009; 296(4): G936-G947. [OPEN ACCESS]
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Schintler, MV; Traunmuller, F; Metzler, J; Kreuzwirt, G; Spendel, S; Mauric, O; Popovic, M; Scharnagl, E; Joukhadar, C High fosfomycin concentrations in bone and peripheral soft tissue in diabetic patients presenting with bacterial foot infection.
J ANTIMICROB CHEMOTHER. 2009; 64(3): 574-578. [OPEN ACCESS]
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