Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Publikationen

Suchbegriffe: PI3K, . Treffer: 63

2023

Dai, Q; Zhang, J; Long, W; Haybaeck, J; Yang, Z Genetic alterations of GI-NECs involving three main signaling pathways.
Cancer Med. 2023; Doi: 10.1002/cam4.5633
Web of Science PubMed FullText FullText_MUG

 

Liebscher, G; Vujic, N; Schreiber, R; Heine, M; Krebiehl, C; Duta-Mare, M; Lamberti, G; de, Smet, CH; Hess, MW; Eichmann, TO; Hölzl, S; Scheja, L; Heeren, J; Kratky, D; Huber, LA The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue.
Mol Metab. 2023; 101705 Doi: 10.1016/j.molmet.2023.101705
PubMed FullText FullText_MUG

 

2022

Abdellatif, M; Eisenberg, T; Heberle, AM; Thedieck, K; Kroemer, G; Sedej, S Cardiac PI3K p110 alpha attenuation delays aging and extends lifespan
CELL STRESS. 2022; 6(8): 72-75. Doi: 10.15698/cst2022.08.270 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abdellatif, M; Madeo, F; Kroemer, G; Sedej, S Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.
Autophagy. 2022; 18(10):2500-2502 Doi: 10.1080/15548627.2022.2095835 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Huang, R; Dai, Q; Yang, R; Duan, Y; Zhao, Q; Haybaeck, J; Yang, Z A Review: PI3K/AKT/mTOR Signaling Pathway and Its Regulated Eukaryotic Translation Initiation Factors May Be a Potential Therapeutic Target in Esophageal Squamous Cell Carcinoma.
Front Oncol. 2022; 12: 817916 Doi: 10.3389/fonc.2022.817916 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Lindenmann, J; Kamolz, L; Graier, W; Smolle, J; Smolle-Juettner, FM Hyperbaric Oxygen Therapy and Tissue Regeneration: A Literature Survey.
Biomedicines. 2022; 10(12): Doi: 10.3390/biomedicines10123145 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Rüschoff, JH; Haberecker, M; Tsourti, Z; Nackaerts, K; de, Perrot, M; Brcic, L; Nadal, E; Tsimpoukis, S; Gray, SG; Ampollini, L; Aerts, JG; Felley-Bosco, E; Kirschner, MB; Monkhorst, K; Weynand, B; Bavaghar-Zaeimi, F; Samarzija, M; Llatjos, R; Finn, SP; Silini, E; von, der, Thüsen, J; Marti, N; Vervita, K; Kammler, R; Peters, S; Stahel, RA; Baas, P; Opitz, I, , ETOP, Mesoscape, consortium Expression of phosphorylated ribosomal protein S6 in mesothelioma patients - correlation with clinico-pathological characteristics and outcome: results from the European Thoracic Oncology Platform (ETOP) Mesoscape project.
Mod Pathol. 2022; 35(12):1888-1899 Doi: 10.1038/s41379-022-01145-0 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2021

Álvarez, RM; García, AB; Riesco-Fagundo, C; Martín, JI; Varela, C; Rodríguez, Hergueta, A; González, Cantalapiedra, E; Oyarzabal, J; Di, Geronimo, B; Lorenzo, M; Albarrán, MI; Cebriá, A; Cebrián, D; Martínez-González, S; Blanco-Aparicio, C; Pastor, J Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors.
Eur J Med Chem. 2021; 211: 113109 Doi: 10.1016/j.ejmech.2020.113109
Web of Science PubMed FullText FullText_MUG

 

Krassnig, S; Wohlrab, C; Golob-Schwarzl, N; Raicht, A; Schatz, C; Birkl-Toeglhofer, AM; Skofler, C; Gantenbein, N; Leoni, M; Asslaber, M; Leber, SL; Mahdy-Ali, K; von Campe, G; Mayer, M; Borenich, A; Weis, S; Benesch, M; Haybaeck, J A Profound Basic Characterization of eIFs in Gliomas: Identifying eIF3I and 4H as Potential Novel Target Candidates in Glioma Therapy.
Cancers (Basel). 2021; 13(6): Doi: 10.3390/cancers13061482 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Martínez-González, S; Alvarez, RM; Martín, JI; García, AB; Riesco-Fagundo, C; Varela, C; Rodríguez, Hergueta, A; González, Cantalapiedra, E; Albarrán, MI; Gómez-Casero, E; Cebriá, A; Aguirre, E; Ajenjo, N; Cebrián, D; Di, Geronimo, B; Cunningham, D; O'Neill, M; Dave, HPG; Blanco-Aparicio, C; Pastor, J Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors.
ACS Med Chem Lett. 2021; 12(11): 1794-1801. Doi: 10.1021/acsmedchemlett.1c00412 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Popper, H; Brcic, L Diagnosis and Molecular Profiles of Large Cell Neuroendocrine Carcinoma With Potential Targets for Therapy.
FRONT ONCOL. 2021; 11: 655752 Doi: 10.3389/fonc.2021.655752 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Skofler, C; Kleinegger, F; Krassnig, S; Birkl-Toeglhofer, AM; Singer, G; Till, H; Benesch, M; Cencic, R; Porco, JA; Pelletier, J; Castellani, C; Raicht, A; Izycka-Swieszewska, E; Czapiewski, P; Haybaeck, J Eukaryotic Translation Initiation Factor 4AI: A Potential Novel Target in Neuroblastoma.
Cells. 2021; 10(2): Doi: 10.3390/cells10020301 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2020

Duan, Y; Haybaeck, J; Yang, Z Therapeutic Potential of PI3K/AKT/mTOR Pathway in Gastrointestinal Stromal Tumors: Rationale and Progress.
Cancers (Basel). 2020; 12(10): Doi: 10.3390/cancers12102972 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Golob-Schwarzl, N; Puchas, P; Gogg-Kamerer, M; Weichert, W; Göppert, B; Haybaeck, J New Pancreatic Cancer Biomarkers eIF1, eIF2D, eIF3C and eIF6 Play a Major Role in Translational Control in Ductal Adenocarcinoma.
Anticancer Res. 2020; 40(6):3109-3118 Doi: 10.21873/anticanres.14292 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Roula, D; Theiler, A; Luschnig, P; Sturm, GJ; Tomazic, PV; Marsche, G; Heinemann, A; Sturm, EM Apolipoprotein A-IV acts as an endogenous anti-inflammatory protein and is reduced in treatment-naïve allergic patients and allergen-challenged mice.
Allergy. 2020; 75(2):392-402 Doi: 10.1111/all.14022 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Terbuch, A; Tiu, C; Candilejo, IM; Scaranti, M; Curcean, A; Bar, D; Estevez Timon, M; Ameratunga, M; Ang, JE; Ratoff, J; Minchom, AR; Banerji, U; de Bono, JS; Tunariu, N; Lopez, JS Radiological Patterns of Drug-induced Interstitial Lung Disease (DILD) in Early-phase Oncology Clinical Trials.
Clin Cancer Res. 2020; 26(18):4805-4813 Doi: 10.1158/1078-0432.CCR-20-0454
Web of Science PubMed FullText FullText_MUG

 

2019

Schwarzenbacher, D; Klec, C; Pasculli, B; Cerk, S; Rinner, B; Karbiener, M; Ivan, C; Barbano, R; Ling, H; Wulf-Goldenberg, A; Stanzer, S; Rinnerthaler, G; Stoeger, H; Bauernhofer, T; Haybaeck, J; Hoefler, G; Jahn, SW; Parrella, P; Calin, GA; Pichler, M MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors.
Breast Cancer Res. 2019; 21(1): 20-20. Doi: 10.1186/s13058-019-1104-5 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2018

Cooney, JD; Lin, AP; Jiang, D; Wang, L; Suhasini, AN; Myers, J; Qiu, Z; Wölfler, A; Sill, H; Aguiar, RCT Synergistic Targeting of the Regulatory and Catalytic Subunits of PI3Kδ in Mature B-cell Malignancies.
Clin Cancer Res. 2018; 24(5):1103-1113 Doi: 10.1158/1078-0432.CCR-17-2218 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Frille, A; Leithner, K; Olschewski, A; Olschewski, H; Wohlkönig, C; Hrzenjak, A No erythropoietin-induced growth is observed in non-small cell lung cancer cells.
Int J Oncol. 2018; 52(2): 518-526. Doi: 10.3892/ijo.2017.4225 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Zboray, K; Mohrherr, J; Stiedl, P; Pranz, K; Wandruszka, L; Grabner, B; Eferl, R; Moriggl, R; Stoiber, D; Sakamoto, K; Wagner, KU; Popper, H; Casanova, E; Moll, HP AKT3 drives adenoid cystic carcinoma development in salivary glands.
Cancer Med. 2018; 7(2):445-453 Doi: 10.1002/cam4.1293 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Zhou, XA; Louissaint, A; Wenzel, A; Yang, J; Martinez-Escala, ME; Moy, AP; Morgan, EA; Paxton, CN; Hong, B; Andersen, EF; Guitart, J; Behdad, A; Cerroni, L; Weinstock, DM; Choi, J Genomic Analyses Identify Recurrent Alterations in Immune Evasion Genes in Diffuse Large B-Cell Lymphoma, Leg Type.
J INVEST DERMATOL. 2018; 138(11): 2365-2376. Doi: 10.1016/j.jid.2018.04.038 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2017

Cuppens, T; Annibali, D; Coosemans, A; Trovik, J; Ter Haar, N; Colas, E; Garcia-Jimenez, A; Van de Vijver, K; Kruitwagen, RP; Brinkhuis, M; Zikan, M; Dundr, P; Huvila, J; Carpén, O; Haybaeck, J; Moinfar, F; Salvesen, HB; Stukan, M; Mestdagh, C; Zweemer, RP; Massuger, LF; Mallmann, MR; Wardelmann, E; Mints, M; Verbist, G; Thomas, D; Gommé, E; Hermans, E; Moerman, P; Bosse, T; Amant, F Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Clin Cancer Res. 2017; 23(5):1274-1285 Doi: 10.1158/1078-0432.CCR-16-2149 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Golob-Schwarzl, N; Krassnig, S; Toeglhofer, AM; Park, YN; Gogg-Kamerer, M; Vierlinger, K; Schröder, F; Rhee, H; Schicho, R; Fickert, P; Haybaeck, J New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors.
Eur J Cancer. 2017; 83(60):56-70 Doi: 10.1016/j.ejca.2017.06.003
Web of Science PubMed FullText FullText_MUG

 

Golob-Schwarzl, N; Schweiger, C; Koller, C; Krassnig, S; Gogg-Kamerer, M; Gantenbein, N; Toeglhofer, AM; Wodlej, C; Bergler, H; Pertschy, B; Uranitsch, S; Holter, M; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Reinhard, C; Regenbrecht, C; Schicho, R; Fickert, P; Lax, S; Haybaeck, J Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.
Oncotarget. 2017; 8(60):101224-101243 Doi: 10.18632/oncotarget.20642 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Zeitelhofer, M; Adzemovic, MZ; Gomez-Cabrero, D; Bergman, P; Hochmeister, S; N'diaye, M; Paulson, A; Ruhrmann, S; Almgren, M; Tegnér, JN; Ekström, TJ; Guerreiro-Cacais, AO; Jagodic, M Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬.
Proc Natl Acad Sci U S A. 2017; 114(9):E1678-E1687 Doi: 10.1073/pnas.1615783114 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2016

Adams, HH; Hibar, DP; Chouraki, V; Stein, JL; Nyquist, PA; Rentería, ME; Trompet, S; Arias-Vasquez, A; Seshadri, S; Desrivières, S; Beecham, AH; Jahanshad, N; Wittfeld, K; Van der Lee, SJ; Abramovic, L; Alhusaini, S; Amin, N; Andersson, M; Arfanakis, K; Aribisala, BS; Armstrong, NJ; Athanasiu, L; Axelsson, T; Beiser, A; Bernard, M; Bis, JC; Blanken, LM; Blanton, SH; Bohlken, MM; Boks, MP; Bralten, J; Brickman, AM; Carmichael, O; Chakravarty, MM; Chauhan, G; Chen, Q; Ching, CR; Cuellar-Partida, G; Braber, AD; Doan, NT; Ehrlich, S; Filippi, I; Ge, T; Giddaluru, S; Goldman, AL; Gottesman, RF; Greven, CU; Grimm, O; Griswold, ME; Guadalupe, T; Hass, J; Haukvik, UK; Hilal, S; Hofer, E; Hoehn, D; Holmes, AJ; Hoogman, M; Janowitz, D; Jia, T; Kasperaviciute, D; Kim, S; Klein, M; Kraemer, B; Lee, PH; Liao, J; Liewald, DC; Lopez, LM; Luciano, M; Macare, C; Marquand, A; Matarin, M; Mather, KA; Mattheisen, M; Mazoyer, B; McKay, DR; McWhirter, R; Milaneschi, Y; Mirza-Schreiber, N; Muetzel, RL; Maniega, SM; Nho, K; Nugent, AC; Loohuis, LM; Oosterlaan, J; Papmeyer, M; Pappa, I; Pirpamer, L; Pudas, S; Pütz, B; Rajan, KB; Ramasamy, A; Richards, JS; Risacher, SL; Roiz-Santiañez, R; Rommelse, N; Rose, EJ; Royle, NA; Rundek, T; Sämann, PG; Satizabal, CL; Schmaal, L; Schork, AJ; Shen, L; Shin, J; Shumskaya, E; Smith, AV; Sprooten, E; Strike, LT; Teumer, A; Thomson, R; Tordesillas-Gutierrez, D; Toro, R; Trabzuni, D; Vaidya, D; Van der Grond, J; Van der Meer, D; Van Donkelaar, MM; Van Eijk, KR; Van Erp, TG; Van Rooij, D; Walton, E; Westlye, LT; Whelan, CD; Windham, BG; Winkler, AM; Woldehawariat, G; Wolf, C; Wolfers, T; Xu, B; Yanek, LR; Yang, J; Zijdenbos, A; Zwiers, MP; Agartz, I; Aggarwal, NT; Almasy, L; Ames, D; Amouyel, P; Andreassen, OA; Arepalli, S; Assareh, AA; Barral, S; Bastin, ME; Becker, DM; Becker, JT; Bennett, DA; Blangero, J; van Bokhoven, H; Boomsma, DI; Brodaty, H; Brouwer, RM; Brunner, HG; Buckner, RL; Buitelaar, JK; Bulayeva, KB; Cahn, W; Calhoun, VD; Cannon, DM; Cavalleri, GL; Chen, C; Cheng, CY; Cichon, S; Cookson, MR; Corvin, A; Crespo-Facorro, B; Curran, JE; Czisch, M; Dale, AM; Davies, GE; De Geus, EJ; De Jager, PL; de Zubicaray, GI; Delanty, N; Depondt, C; DeStefano, AL; Dillman, A; Djurovic, S; Donohoe, G; Drevets, WC; Duggirala, R; Dyer, TD; Erk, S; Espeseth, T; Evans, DA; Fedko, IO; Fernández, G; Ferrucci, L; Fisher, SE; Fleischman, DA; Ford, I; Foroud, TM; Fox, PT; Francks, C; Fukunaga, M; Gibbs, JR; Glahn, DC; Gollub, RL; Göring, HH; Grabe, HJ; Green, RC; Gruber, O; Gudnason, V; Guelfi, S; Hansell, NK; Hardy, J; Hartman, CA; Hashimoto, R; Hegenscheid, K; Heinz, A; Le Hellard, S; Hernandez, DG; Heslenfeld, DJ; Ho, BC; Hoekstra, PJ; Hoffmann, W; Hofman, A; Holsboer, F; Homuth, G; Hosten, N; Hottenga, JJ; Hulshoff Pol, HE; Ikeda, M; Ikram, MK; Jack, CR; Jenkinson, M; Johnson, R; Jönsson, EG; Jukema, JW; Kahn, RS; Kanai, R; Kloszewska, I; Knopman, DS; Kochunov, P; Kwok, JB; Lawrie, SM; Lemaître, H; Liu, X; Longo, DL; Longstreth, WT; Lopez, OL; Lovestone, S; Martinez, O; Martinot, JL; Mattay, VS; McDonald, C; McIntosh, AM; McMahon, KL; McMahon, FJ; Mecocci, P; Melle, I; Meyer-Lindenberg, A; Mohnke, S; Montgomery, GW; Morris, DW; Mosley, TH; Mühleisen, TW; Müller-Myhsok, B; Nalls, MA; Nauck, M; Nichols, TE; Niessen, WJ; Nöthen, MM; Nyberg, L; Ohi, K; Olvera, RL; Ophoff, RA; Pandolfo, M; Paus, T; Pausova, Z; Penninx, BW; Pike, GB; Potkin, SG; Psaty, BM; Reppermund, S; Rietschel, M; Roffman, JL; Romanczuk-Seiferth, N; Rotter, JI; Ryten, M ... Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Nat Neurosci. 2016; 19(12):1569-1582 Doi: 10.1038/nn.4398 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Kaushik, AK; Shojaie, A; Panzitt, K; Sonavane, R; Venghatakrishnan, H; Manikkam, M; Zaslavsky, A; Putluri, V; Vasu, VT; Zhang, Y; Khan, AS; Lloyd, S; Szafran, AT; Dasgupta, S; Bader, DA; Stossi, F; Li, H; Samanta, S; Cao, X; Tsouko, E; Huang, S; Frigo, DE; Chan, L; Edwards, DP; Kaipparettu, BA; Mitsiades, N; Weigel, NL; Mancini, M; McGuire, SE; Mehra, R; Ittmann, MM; Chinnaiyan, AM; Putluri, N; Palapattu, GS; Michailidis, G; Sreekumar, A Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer.
Nat Commun. 2016; 7(7):11612-11612 Doi: 10.1038/ncomms11612 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Koyani, CN; Kitz, K; Rossmann, C; Bernhart, E; Huber, E; Trummer, C; Windischhofer, W; Sattler, W; Malle, E Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death.
Biochem Pharmacol. 2016; 104:29-41 Doi: 10.1016/j.bcp.2016.01.011 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Metz, HE; Kargl, J; Busch, SE; Kim, KH; Kurland, BF; Abberbock, SR; Randolph-Habecker, J; Knoblaugh, SE; Kolls, JK; White, MF; Houghton, AM Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.
Proc Natl Acad Sci U S A. 2016; 113(31):8795-8800 Doi: 10.1073/pnas.1601989113 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Sadovnik, I; Hoelbl-Kovacic, A; Herrmann, H; Eisenwort, G; Cerny-Reiterer, S; Warsch, W; Hoermann, G; Greiner, G; Blatt, K; Peter, B; Stefanzl, G; Berger, D; Bilban, M; Herndlhofer, S; Sill, H; Sperr, WR; Streubel, B; Mannhalter, C; Holyoake, TL; Sexl, V; Valent, P Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.
Clin Cancer Res. 2016; 22(8):2051-2061 Doi: 10.1158/1078-0432.CCR-15-0767 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2015

Milewska, M; Romano, D; Herrero, A; Guerriero, ML; Birtwistle, M; Quehenberger, F; Hatzl, S; Kholodenko, BN; Segatto, O; Kolch, W; Zebisch, A Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation.
PLoS One. 2015; 10(6):e0129859-e0129859 Doi: 10.1371/journal.pone.0129859 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Schiefer, AI; Vesely, P; Hassler, MR; Egger, G; Kenner, L The role of AP-1 and epigenetics in ALCL.
Front Biosci (Schol Ed). 2015; 7(5):226-235 Doi: 10.2741/436
PubMed FullText FullText_MUG

 

Shain, AH; Garrido, M; Botton, T; Talevich, E; Yeh, I; Sanborn, JZ; Chung, J; Wang, NJ; Kakavand, H; Mann, GJ; Thompson, JF; Wiesner, T; Roy, R; Olshen, AB; Gagnon, A; Gray, JW; Huh, N; Hur, JS; Busam, KJ; Scolyer, RA; Cho, RJ; Murali, R; Bastian, BC Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Nat Genet. 2015; 47(10): 1194-1199. Doi: 10.1038/ng.3382 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Sturm, EM; Parzmair, GP; Radnai, B; Frei, RB; Sturm, GJ; Hammer, A; Schuligoi, R; Lippe, IT; Heinemann, A Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils.
Eur J Immunol. 2015; 45(5):1548-1559 Doi: 10.1002/eji.201445196 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Zakharova, IO; Sokolova, TV; Akhmetshina, AO; Avrova, NF Role of Protein Kinase Akt Activation in Protective Effect of Ganglioside GM1 on PC12 Cells Exposed to H2O2.
Bull Exp Biol Med. 2015; 159(5): 610-613. Doi: 10.1007/s10517-015-3026-2
Web of Science PubMed FullText FullText_MUG

 

2014

Lebrun-Julien, F; Bachmann, L; Norrmén, C; Trötzmüller, M; Köfeler, H; Rüegg, MA; Hall, MN; Suter, U Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination.
J NEUROSCI. 2014; 34(25): 8432-8448. Doi: 10.1523/JNEUROSCI.1105-14.2014 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Pradhan, SA; Rather, MI; Tiwari, A; Bhat, VK; Kumar, A Evidence that TSC2 acts as a transcription factor and binds to and represses the promoter of Epiregulin.
Nucleic Acids Res. 2014; 42(10): 6243-6255. Doi: 10.1093/nar/gku278 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Quan, P; Moinfar, F; Kufferath, I; Absenger, M; Kueznik, T; Denk, H; Zatloukal, K; Haybaeck, J Effects of targeting endometrial stromal sarcoma cells via histone deacetylase and PI3K/AKT/mTOR signaling.
Anticancer Res. 2014; 34(6):2883-2897
Web of Science PubMed

 

Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Nojima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Heitzer, E; Geigl, JB; Windpassinger, C; Hoefler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.
Nat Commun. 2014; 5(10):5191-5191 Doi: 10.1038/ncomms6191 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Seidel, MG Autoimmune and other cytopenias in primary immunodeficiencies: pathomechanisms, novel differential diagnoses, and treatment.
Blood. 2014; 124(15):2337-2344 Doi: 10.1182/blood-2014-06-583260 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Walther, S; Pluteanu, F; Renz, S; Nikonova, Y; Maxwell, JT; Yang, LZ; Schmidt, K; Edwards, JN; Wakula, P; Groschner, K; Maier, LS; Spiess, J; Blatter, LA; Pieske, B; Kockskämper, J Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177.
Am J Physiol Heart Circ Physiol. 2014; 307(5):H689-H700 Doi: 10.1152/ajpheart.00694.2013 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2013

Fock, V; Mairhofer, M; Otti, GR; Hiden, U; Spittler, A; Zeisler, H; Fiala, C; Knöfler, M; Pollheimer, J Macrophage-derived IL-33 is a critical factor for placental growth.
J Immunol. 2013; 191(7):3734-3743 Doi: 10.4049/jimmunol.1300490 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Rinner, B; Weinhaeusel, A; Lohberger, B; Froehlich, EV; Pulverer, W; Fischer, C; Meditz, K; Scheipl, S; Trajanoski, S; Guelly, C; Leithner, A; Liegl, B Chordoma characterization of significant changes of the DNA methylation pattern.
PLoS One. 2013; 8(3):e56609-e56609 Doi: 10.1371/journal.pone.0056609 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2012

Hafner, C; Houben, R; Baeurle, A; Ritter, C; Schrama, D; Landthaler, M; Becker, JC Activation of the PI3K/AKT pathway in Merkel cell carcinoma.
PLoS One. 2012; 7(2):e31255-e31255 Doi: 10.1371/journal.pone.0031255 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Wygrecka, M; Zakrzewicz, D; Taborski, B; Didiasova, M; Kwapiszewska, G; Preissner, KT; Markart, P TGF-β1 induces tissue factor expression in human lung fibroblasts in a PI3K/JNK/Akt-dependent and AP-1-dependent manner.
Am J Respir Cell Mol Biol. 2012; 47(5):614-627 Doi: 10.1165/rcmb.2012-0097OC
Web of Science PubMed FullText FullText_MUG

 

2011

Dengler, MA; Staiger, AM; Gutekunst, M; Hofmann, U; Doszczak, M; Scheurich, P; Schwab, M; Aulitzky, WE; van der Kuip, H Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis.
PLoS One. 2011; 6(9):e25139-e25139 Doi: 10.1371/journal.pone.0025139 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Erttmann, SF; Bast, A; Seidel, J; Breitbach, K; Walther, R; Steinmetz, I PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2.
Free Radic Biol Med. 2011; 51(3):626-640 Doi: 10.1016/j.freeradbiomed.2011.05.022
Web of Science PubMed FullText FullText_MUG

 

Mantoni, TS; Lunardi, S; Al-Assar, O; Masamune, A; Brunner, TB Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling.
Cancer Res. 2011; 71(10):3453-8 Doi: 10.1158/0008-5472.CAN-10-1633 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2010

Bast, A; Erttmann, SF; Walther, R; Steinmetz, I Influence of iNOS and COX on peroxiredoxin gene expression in primary macrophages.
Free Radic Biol Med. 2010; 49(12):1881-1891 Doi: 10.1016/j.freeradbiomed.2010.09.015
Web of Science PubMed FullText FullText_MUG

 

Doi, T; Ruttenstock, E; Dingemann, J; Puri, P Spatiotemporal alteration in phosphatidylinositide 3-kinase-serine/threonine protein kinase B signaling in the nitrofen-induced hypoplastic lung.
J Pediatr Surg. 2010; 45(2):366-371 Doi: 10.1016/j.jpedsurg.2009.10.075
Web of Science PubMed FullText FullText_MUG

 

Weitere 50 Treffer anzeigen

↑ Seitenanfang / Navigation

© Med Uni Graz • Impressum