Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: NEUTROPHILS - METABOLISM , . Treffer: 35

2022

Kraft, JD; Blomgran, R; Bergström, I; Soták, M; Clark, M; Rani, A; Rajan, MR; Dalli, J; Nyström, S; Quiding-Järbrink, M; Bromberg, J; Skoog, P; Börgeson, E Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis.
FASEB J. 2022; 36(3): e22173 Doi: 10.1096/fj.202101219RR [OPEN ACCESS]
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Zhang, H; Zhu, X; Friesen, TJ; Kwak, JW; Pisarenko, T; Mekvanich, S; Velasco, MA; Randolph, TW; Kargl, J; Houghton, AM Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils.
J Clin Invest. 2022; 132(22): Doi: 10.1172/JCI153643 [OPEN ACCESS]
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2021

Frei, R; Nordlohne, J; Hüser, U; Hild, S; Schmidt, J; Eitner, F; Grundmann, M Allosteric targeting of the FFA2 receptor (GPR43) restores responsiveness of desensitized human neutrophils.
J Leukoc Biol. 2021; 109(4):741-751 Doi: 10.1002/JLB.2A0720-432R [OPEN ACCESS]
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Watts, ER; Howden, AJ; Morrison, T; Sadiku, P; Hukelmann, J; von, Kriegsheim, A; Ghesquiere, B; Murphy, F; Mirchandani, AS; Humphries, DC; Grecian, R; Ryan, EM; Coelho, P; Blanco, GR; Plant, TM; Dickinson, RS; Finch, A; Vermaelen, W; Cantrell, DA; Whyte, MK; Walmsley, SR Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism.
J Clin Invest. 2021; 131(10): Doi: 10.1172/JCI134073 [OPEN ACCESS]
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2019

Kargl, J; Zhu, X; Zhang, H; Yang, GHY; Friesen, TJ; Shipley, M; Maeda, DY; Zebala, JA; McKay-Fleisch, J; Meredith, G; Mashadi-Hossein, A; Baik, C; Pierce, RH; Redman, MW; Thompson, JC; Albelda, SM; Bolouri, H; Houghton, AM Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC.
JCI Insight. 2019; 4(24): Doi: 10.1172/jci.insight.130850 [OPEN ACCESS]
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2018

Aringer, I; Artinger, K; Kirsch, AH; Schabhüttl, C; Jandl, K; Bärnthaler, T; Mooslechner, AA; Herzog, SA; Uhlig, M; Kirsch, A; Frank, S; Banas, M; Pollheimer, M; Eller, P; Rosenkranz, AR; Heinemann, A; Eller, K Blockade of prostaglandin E2 receptor 4 ameliorates nephrotoxic serum nephritis.
Am J Physiol Renal Physiol. 2018; 315(6):F1869-F1880 Doi: 10.1152/ajprenal.00113.2018 [OPEN ACCESS]
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2017

Duchene, J; Novitzky-Basso, I; Thiriot, A; Casanova-Acebes, M; Bianchini, M; Etheridge, SL; Hub, E; Nitz, K; Artinger, K; Eller, K; Caamaño, J; Rülicke, T; Moss, P; Megens, RTA; von Andrian, UH; Hidalgo, A; Weber, C; Rot, A Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis.
Nat Immunol. 2017; 18(7):753-761 Doi: 10.1038/ni.3763 [OPEN ACCESS]
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Salminen, A; Vlachopoulou, E; Havulinna, AS; Tervahartiala, T; Sattler, W; Lokki, ML; Nieminen, MS; Perola, M; Salomaa, V; Sinisalo, J; Meri, S; Sorsa, T; Pussinen, PJ Genetic Variants Contributing to Circulating Matrix Metalloproteinase 8 Levels and Their Association With Cardiovascular Diseases: A Genome-Wide Analysis.
Circ Cardiovasc Genet. 2017; 10(6): Doi: 10.1161/CIRCGENETICS.117.001731 [OPEN ACCESS]
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2016

Lemesch, S; Ribitsch, W; Schilcher, G; Spindelböck, W; Hafner-Gießauf, H; Marsche, G; Pasterk, L; Payerl, D; Schmerböck, B; Tawdrous, M; Rosenkranz, AR; Stiegler, P; Kager, G; Hallström, S; Oettl, K; Eberhard, K; Horvath, A; Leber, B; Stadlbauer, V Mode of renal replacement therapy determines endotoxemia and neutrophil dysfunction in chronic kidney disease.
Sci Rep. 2016; 6(6):34534-34534 Doi: 10.1038/srep34534 [OPEN ACCESS]
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Wicki, S; Gurzeler, U; Wei-Lynn Wong, W; Jost, PJ; Bachmann, D; Kaufmann, T Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils.
Cell Death Dis. 2016; 7(10):e2422-e2422 Doi: 10.1038/cddis.2016.311 [OPEN ACCESS]
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2015

Bao, Y; Ledderose, C; Graf, AF; Brix, B; Birsak, T; Lee, A; Zhang, J; Junger, WG mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis.
J Cell Biol. 2015; 210(7):1153-1164 Doi: 10.1083/jcb.201503066 [OPEN ACCESS]
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2014

Bao, Y; Ledderose, C; Seier, T; Graf, AF; Brix, B; Chong, E; Junger, WG Mitochondria regulate neutrophil activation by generating ATP for autocrine purinergic signaling.
J Biol Chem. 2014; 289(39):26794-26803 Doi: 10.1074/jbc.M114.572495 [OPEN ACCESS]
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Köffel, R; Meshcheryakova, A; Warszawska, J; Hennig, A; Wagner, K; Jörgl, A; Gubi, D; Moser, D; Hladik, A; Hoffmann, U; Fischer, MB; van den Berg, W; Koenders, M; Scheinecker, C; Gesslbauer, B; Knapp, S; Strobl, H Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation.
Blood. 2014; 124(17):2713-2724 Doi: 10.1182/blood-2014-07-588178 [OPEN ACCESS]
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Sturm, EM; Radnai, B; Jandl, K; Stančić, A; Parzmair, GP; Högenauer, C; Kump, P; Wenzl, H; Petritsch, W; Pieber, TR; Schuligoi, R; Marsche, G; Ferreirós, N; Heinemann, A; Schicho, R Opposing roles of prostaglandin D2 receptors in ulcerative colitis.
J Immunol. 2014; 193(2):827-839 Doi: 10.4049/jimmunol.1303484 [OPEN ACCESS]
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2013

Hasmann, A; Wehrschuetz-Sigl, E; Marold, A; Wiesbauer, H; Schoeftner, R; Gewessler, U; Kandelbauer, A; Schiffer, D; Schneider, KP; Binder, B; Schintler, M; Guebitz, GM Analysis of myeloperoxidase activity in wound fluids as a marker of infection.
Ann Clin Biochem. 2013; 50(Pt 3):245-254 Doi: 10.1258/acb.2011.010249 [OPEN ACCESS]
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Seper, A; Hosseinzadeh, A; Gorkiewicz, G; Lichtenegger, S; Roier, S; Leitner, DR; Röhm, M; Grutsch, A; Reidl, J; Urban, CF; Schild, S Vibrio cholerae evades neutrophil extracellular traps by the activity of two extracellular nucleases.
PLoS Pathog. 2013; 9(9):e1003614-e1003614 Doi: 10.1371/journal.ppat.1003614 [OPEN ACCESS]
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2012

Leber, B; Tripolt, NJ; Blattl, D; Eder, M; Wascher, TC; Pieber, TR; Stauber, R; Sourij, H; Oettl, K; Stadlbauer, V The influence of probiotic supplementation on gut permeability in patients with metabolic syndrome: an open label, randomized pilot study.
Eur J Clin Nutr. 2012; 66(10):1110-1115 Doi: 10.1038/ejcn.2012.103 [OPEN ACCESS]
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2011

Balenga, NA; Aflaki, E; Kargl, J; Platzer, W; Schröder, R; Blättermann, S; Kostenis, E; Brown, AJ; Heinemann, A; Waldhoer, M GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils.
Cell Res. 2011; 21(10):1452-1469 Doi: 10.1038/cr.2011.60 [OPEN ACCESS]
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2009

Rensen, SS; Slaats, Y; Nijhuis, J; Jans, A; Bieghs, V; Driessen, A; Malle, E; Greve, JW; Buurman, WA Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis.
Am J Pathol. 2009; 175(4): 1473-1482. Doi: 10.2353/ajpath.2009.080999 [OPEN ACCESS]
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2004

Kuijpers, TW; Maianski, NA; Tool, AT; Becker, K; Plecko, B; Valianpour, F; Wanders, RJ; Pereira, R; Van Hove, J; Verhoeven, AJ; Roos, D; Baas, F; Barth, PG Neutrophils in Barth syndrome (BTHS) avidly bind annexin-V in the absence of apoptosis.
Blood. 2004; 103(10):3915-3923 Doi: 10.1182/blood-2003-11-3940 [OPEN ACCESS]
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2003

Rose, F; Hattar, K; Gakisch, S; Grimminger, F; Olschewski, H; Seeger, W; Tschuschner, A; Schermuly, RT; Weissmann, N; Hanze, J; Sibelius, U; Ghofrani, HA Increased neutrophil mediator release in patients with pulmonary hypertension--suppression by inhaled iloprost.
Thromb Haemost. 2003; 90(6):1141-1149 Doi: 10.1160/TH03-03-0173
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2002

Kähler, CM; Schratzberger, P; Kaufmann, G; Hochleitner, B; Bechter, O; Götsch, C; Wöll, E; Marschang, P; Herold, M; Wiedermann, CJ Transendothelial migration of leukocytes and signalling mechanisms in response to the neuropeptide secretoneurin.
Regul Pept. 2002; 105(1):35-46 Doi: 10.1016/S0167-0115(01)00379-2
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2001

Kormoczi, GF; Wolfel, UM; Rosenkranz, AR; Horl, WH; Oberbauer, R; Zlabinger, GJ Serum proteins modified by neutrophil-derived oxidants as mediators of neutrophil stimulation.
J IMMUNOL. 2001; 167(1): 451-460. Doi: 10.4049/jimmunol.167.1.451 [OPEN ACCESS]
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Ren, Y; Stuart, L; Lindberg, FP; Rosenkranz, AR; Chen, YM; Mayadas, TN; Savill, J Nonphlogistic clearance of late apoptotic neutrophils by macrophages: efficient phagocytosis independent of beta 2 integrins.
J IMMUNOL. 2001; 166(7): 4743-4750. Doi: 10.4049/jimmunol.166.7.4743 [OPEN ACCESS]
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2000

Metnitz, GH; Fischer, M; Bartens, C; Steltzer, H; Lang, T; Druml, W Impact of acute renal failure on antioxidant status in multiple organ failure.
Acta Anaesthesiol Scand. 2000; 44(3):236-240 Doi: 10.1034/j.1399-6576.2000.440304.x
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1999

Metnitz, PG; Bartens, C; Fischer, M; Fridrich, P; Steltzer, H; Druml, W Antioxidant status in patients with acute respiratory distress syndrome.
Intensive Care Med. 1999; 25(2):180-185 Doi: 10.1007/s001340050813
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Rosenkranz, AR; Kormoczi, GF; Thalhammer, F; Menzel, EJ; Horl, WH; Mayer, G; Zlabinger, GJ Novel C5-dependent mechanism of neutrophil stimulation by bioincompatible dialyzer membranes.
J AMER SOC NEPHROL. 1999; 10(1): 128-135. Doi: 10.1681/ASN.V101128 [OPEN ACCESS]
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1997

Tang, T; Rosenkranz, A; Assmann, KJM; Goodman, MJ; GutierrezRamos, JC; Carroll, MC; Cotran, RS; Mayadas, TN A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis.
J EXP MED. 1997; 186(11): 1853-1863. Doi: 10.1084/jem.186.11.1853 [OPEN ACCESS]
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1996

Wenisch, C; Narzt, E; Sessler, DI; Parschalk, B; Lenhardt, R; Kurz, A; Graninger, W Mild intraoperative hypothermia reduces production of reactive oxygen intermediates by polymorphonuclear leukocytes.
Anesth Analg. 1996; 82(4):810-6 Doi: 10.1097/00000539-199604000-00023
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1995

Wiltschke, C; Krainer, M; Nanut, M; Wagner, A; Linkesch, W; Zielinski, CC In vivo administration of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor increases neutrophil oxidative burst activity.
J INTERFERON CYTOKINE RES. 1995; 15(3): 249-253. Doi: 10.1089/jir.1995.15.249
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1994

ROSENKRANZ, AR; TEMPL, E; TRAINDL, O; HEINZL, H; ZLABINGER, GJ Reactive oxygen product formation by human neutrophils as an early marker for biocompatibility of dialysis membranes.
Clin Exp Immunol. 1994; 98(2):300-305 Doi: 10.1111/j.1365-2249.1994.tb06141.x [OPEN ACCESS]
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Schaur, RJ; Dussing, G; Kink, E; Schauenstein, E; Posch, W; Kukovetz, E; Egger, G The lipid peroxidation product 4-hydroxynonenal is formed by--and is able to attract--rat neutrophils in vivo.
FREE RADICAL RES . 1994; 20(6): 365-373. Doi: 10.3109/10715769409145636
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1993

ROSENKRANZ, AR; MAJDIC, O; STOCKL, J; PICKL, W; STOCKINGER, H; KNAPP, W Induction of neutrophil homotypic adhesion via sialophorin (CD43), a surface sialoglycoprotein restricted to haemopoietic cells.
Immunology. 1993; 80(3):431-438 [OPEN ACCESS]
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1989

von Ritter, C; Grisham, MB; Hollwarth, M; Inauen, W; Granger, DN Neutrophil-derived oxidants mediate formyl-methionyl-leucyl-phenylalanine-induced increases in mucosal permeability in rats.
Gastroenterology. 1989; 97(3):778-780 Doi: 10.1016/0016-5085(89)90654-9
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1982

Aehringhaus, U; Wölbling, RH; König, W; Patrono, C; Peskar, BM; Peskar, BA Release of leukotriene C4 from human polymorphonuclear leucocytes as determined by radioimmunoassay.
FEBS Lett. 1982; 146(1):111-114 Doi: 10.1016/0014-5793(82)80715-1
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