Suchbegriffe: NEOPLASMS - GENETICS , . Treffer: 608
Seidel, MG; Brcic, L; Hoefler, G; Hutter, C; Minkov, M; Steffen, LS; Zebisch, A; Benesch, M
Concurrence of a kinase-dead BRAF and an oncogenic KRAS gain-of-function mutation in juvenile xanthogranuloma.
Pediatr Blood Cancer. 2023; 70(4):e30060
Doi: 10.1002/pbc.30060
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Olthof, PB; Buettner, S; Andreatos, N; Wang, J; Løes, IM; Wagner, D; Sasaki, K; Macher-Beer, A; Kamphues, C; Pozios, I; Seeliger, H; Morioka, D; Imai, K; Kaczirek, K; Pawlik, TM; Poultsides, G; Burkhart, R; Endo, I; Baba, H; Kornprat, P; Aucejo, FN; Lønning, PE; Beyer, K; Weiss, MJ; Wolfgang, CL; Kreis, ME; Margonis, GA
KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations.
BRIT J SURG. 2022; 109(9): 804-807.
Doi: 10.1093/bjs/znac147
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Penkert, J; Strüwe, FJ; Dutzmann, CM; Doergeloh, BB; Montellier, E; Freycon, C; Keymling, M; Schlemmer, HP; Sänger, B; Hoffmann, B; Gerasimov, T; Blattmann, C; Fetscher, S; Frühwald, M; Hettmer, S; Kordes, U; Ridola, V; Kroiss, Benninger, S; Mastronuzzi, A; Schott, S; Nees, J; Prokop, A; Redlich, A; Seidel, MG; Zimmermann, S; Pajtler, KW; Pfister, SM; Hainaut, P; Kratz, CP
Genotype-phenotype associations within the Li-Fraumeni spectrum: a report from the German Registry.
J Hematol Oncol. 2022; 15(1): 107
Doi: 10.1186/s13045-022-01332-1
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Wirth, AK; Wange, L; Vosberg, S; Henrich, KO; Rausch, C; Özdemir, E; Zeller, CM; Richter, D; Feuchtinger, T; Kaller, M; Hermeking, H; Greif, PA; Senft, D; Jurinovic, V; Bahrami, E; Jayavelu, AK; Westermann, F; Mann, M; Enard, W; Herold, T; Jeremias, I
In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance.
Leukemia. 2022; 36(12):2863-2874
Doi: 10.1038/s41375-022-01726-7
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Soriano, I; Vazquez, E; De, Leon, N; Bertrand, S; Heitzer, E; Toumazou, S; Bo, Z; Palles, C; Pai, CC; Humphrey, TC; Tomlinson, I; Cotterill, S; Kearsey, SE
Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.
PLOS GENET. 2021; 17(7): e1009526
Doi: 10.1371/journal.pgen.1009526
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Zalyte, E; Dedonyte, V; Kurlinkus, B; Sileikis, A; Schemmer, P; Valius, M
Establishment and Characterization of a New Pancreatic Ductal Adenocarcinoma Cell Line Capan-26.
ANTICANCER RES. 2021; 41(3): 1401-1406.
Doi: 10.21873/anticanres.14897
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Benesch, M; Nemes, K; Neumayer, P; Hasselblatt, M; Timmermann, B; Bison, B; Ebetsberger-Dachs, G; Bourdeaut, F; Dufour, C; Biassoni, V; Morales La Madrid, A; Entz-Werle, N; Laithier, V; Quehenberger, F; Weis, S; Sumerauer, D; Siebert, R; Bens, S; Schneppenheim, R; Kool, M; Modena, P; Fouyssac, F; C Frühwald, M
Spinal cord atypical teratoid/rhabdoid tumors in children: Clinical, genetic, and outcome characteristics in a representative European cohort.
Pediatr Blood Cancer. 2020; 67(1):e28022-e28022
Doi: 10.1002/pbc.28022
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Breitegger, B; Holzer, LA; Beham-Schmid, C; Urban, C; Liegl-Atzwanger, B; Leithner, A
Bone marrow aspirations in Ewing sarcomas: Are they still necessary? A single-center retrospective analysis and review of the literature.
J Cancer Res Ther. 2020; 16(4):713-717
Doi: 10.4103/jcrt.JCRT_941_16
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Fan, K; Gravemeyer, J; Ritter, C; Rasheed, K; Gambichler, T; Moens, U; Shuda, M; Schrama, D; Becker, JC
MCPyV Large T Antigen-Induced Atonal Homolog 1 Is a Lineage-Dependency Oncogene in Merkel Cell Carcinoma.
J Invest Dermatol. 2020; 140(1):56-65
Doi: 10.1016/j.jid.2019.06.135
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Golob-Schwarzl, N; Puchas, P; Gogg-Kamerer, M; Weichert, W; Göppert, B; Haybaeck, J
New Pancreatic Cancer Biomarkers eIF1, eIF2D, eIF3C and eIF6 Play a Major Role in Translational Control in Ductal Adenocarcinoma.
Anticancer Res. 2020; 40(6):3109-3118
Doi: 10.21873/anticanres.14292
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Jean-Quartier, C; Jeanquartier, F; Holzinger, A
Open Data for Differential Network Analysis in Glioma.
Int J Mol Sci. 2020; 21(2):
Doi: 10.3390/ijms21020547
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Lord, SR; Collins, JM; Cheng, WC; Haider, S; Wigfield, S; Gaude, E; Fielding, BA; Pinnick, KE; Harjes, U; Segaran, A; Jha, P; Hoefler, G; Pollak, MN; Thompson, AM; Roy, PG; English, R; Adams, RF; Frezza, C; Buffa, FM; Karpe, F; Harris, AL
Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.
Br J Cancer. 2020; 122(2):258-265
Doi: 10.1038/s41416-019-0665-5
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Matias-Guiu, X; Stanta, G; Carneiro, F; Ryska, A; Hoefler, G; Moch, H; European Society of Pathology (ESP)
The leading role of pathology in assessing the somatic molecular alterations of cancer: Position Paper of the European Society of Pathology.
Virchows Arch. 2020; 476(4):491-497
Doi: 10.1007/s00428-020-02757-0
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Schwaab, J; Naumann, N; Luebke, J; Jawhar, M; Somervaille, TCP; Williams, MS; Frewin, R; Jost, PJ; Lichtenegger, FS; La Rosée, P; Storch, N; Haferlach, T; Horny, HP; Fabarius, A; Haferlach, C; Burchert, A; Hofmann, WK; Cross, NCP; Hochhaus, A; Reiter, A; Metzgeroth, G
Response to tyrosine kinase inhibitors in myeloid neoplasms associated with PCM1-JAK2, BCR-JAK2 and ETV6-ABL1 fusion genes.
Am J Hematol. 2020; 95(7):824-833
Doi: 10.1002/ajh.25825
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Sladky, VC; Knapp, K; Szabo, TG; Braun, VZ; Bongiovanni, L; van den Bos, H; Spierings, DC; Westendorp, B; Curinha, A; Stojakovic, T; Scharnagl, H; Timelthaler, G; Tsuchia, K; Pinter, M; Semmler, G; Foijer, F; de Bruin, A; Reiberger, T; Rohr-Udilova, N; Villunger, A
PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
EMBO Rep. 2020; 21(12):e50893-e50893
Doi: 10.15252/embr.202050893
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Stickel, F; Lutz, P; Buch, S; Nischalke, HD; Silva, I; Rausch, V; Fischer, J; Weiss, KH; Gotthardt, D; Rosendahl, J; Marot, A; Elamly, M; Krawczyk, M; Casper, M; Lammert, F; Buckley, TWM; McQuillin, A; Spengler, U; Eyer, F; Vogel, A; Marhenke, S; von Felden, J; Wege, H; Sharma, R; Atkinson, S; Franke, A; Nehring, S; Moser, V; Schafmayer, C; Spahr, L; Lackner, C; Stauber, RE; Canbay, A; Link, A; Valenti, L; Grove, JI; Aithal, GP; Marquardt, JU; Fateen, W; Zopf, S; Dufour, JF; Trebicka, J; Datz, C; Deltenre, P; Mueller, S; Berg, T; Hampe, J; Morgan, MY
Genetic Variation in HSD17B13 Reduces the Risk of Developing Cirrhosis and Hepatocellular Carcinoma in Alcohol Misusers.
Hepatology. 2020; 72(1):88-102
Doi: 10.1002/hep.30996
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Strandback, E; Lienhart, WD; Hromic-Jahjefendic, A; Bourgeois, B; Högler, A; Waltenstorfer, D; Winkler, A; Zangger, K; Madl, T; Gruber, K; Macheroux, P
A small molecule chaperone rescues the stability and activity of a cancer-associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro.
FEBS Lett. 2020; 594(3):424-438
Doi: 10.1002/1873-3468.13636
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Cho, KR; Cooper, K; Croce, S; Djordevic, B; Herrington, S; Howitt, B; Hui, P; Ip, P; Koebel, M; Lax, S; Quade, BJ; Shaw, P; Vidal, A; Yemelyanova, A; Clarke, B; Hedrick Ellenson, L; Longacre, TA; Shih, IM; McCluggage, WG; Malpica, A; Oliva, E; Parkash, V; Matias-Guiu, X
International Society of Gynecological Pathologists (ISGyP) Endometrial Cancer Project: Guidelines From the Special Techniques and Ancillary Studies Group.
Int J Gynecol Pathol. 2019; 38 Suppl 1(2):S114-S122
Doi: 10.1097/PGP.0000000000000496
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Golob-Schwarzl, N; Wodlej, C; Kleinegger, F; Gogg-Kamerer, M; Birkl-Toeglhofer, AM; Petzold, J; Aigelsreiter, A; Thalhammer, M; Park, YN; Haybaeck, J
Eukaryotic translation initiation factor 6 overexpression plays a major role in the translational control of gallbladder cancer.
J Cancer Res Clin Oncol. 2019; 145(11): 2699-2711.
Doi: 10.1007/s00432-019-03030-x
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Saggini, A; Cerroni, L; Casini, B; Baciorri, F; Cota, C
Primary intrafascial desmoplastic melanoma with pseudoglandular differentiation and aberrant cytokeratins expression: An exceptional presentation.
Pathol Res Pract. 2019; 215(12):152668-152668
Doi: 10.1016/j.prp.2019.152668
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Smolle, MA; Czapiewski, P; Lapińska-Szumczyk, S; Majewska, H; Supernat, A; Zaczek, A; Biernat, W; Golob-Schwarzl, N; Haybaeck, J
The Prognostic Significance of Eukaryotic Translation Initiation Factors (eIFs) in Endometrial Cancer.
Int J Mol Sci. 2019; 20(24):
Doi: 10.3390/ijms20246169
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Washetine, K; Heeke, S; Ribeyre, C; Bourreau, C; Normand, C; Blons, H; Laurent-Puig, P; Mulot, C; Clermont, D; David, M; Clément, B; Dagher, G; Hofman, P
DNAshell Protects DNA Stored at Room Temperature for Downstream Next-Generation Sequencing Studies.
Biopreserv Biobank. 2019; 17(4): 352-354.
Doi: 10.1089/bio.2018.0129
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Alunni-Fabbroni, M; Majunke, L; Trapp, EK; Tzschaschel, M; Mahner, S; Fasching, PA; Fehm, T; Schneeweiss, A; Beck, T; Lorenz, R; Friedl, TWP; Janni, W; Rack, B; SUCCESS Study Group
Whole blood microRNAs as potential biomarkers in post-operative early breast cancer patients.
BMC Cancer. 2018; 18(1):141-141
Doi: 10.1186/s12885-018-4020-7
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Alvarez, MJ; Subramaniam, PS; Tang, LH; Grunn, A; Aburi, M; Rieckhof, G; Komissarova, EV; Hagan, EA; Bodei, L; Clemons, PA; Dela Cruz, FS; Dhall, D; Diolaiti, D; Fraker, DA; Ghavami, A; Kaemmerer, D; Karan, C; Kidd, M; Kim, KM; Kim, HC; Kunju, LP; Langel, U; Li, Z; Lee, J; Li, H; LiVolsi, V; Pfragner, R; Schwach, G; Rainey, AR; Realubit, RB; Remotti, H; Regberg, J; Roses, R; Rustgi, A; Sepulveda, AR; Serra, S; Shi, CJ; Yuan, XP; Barberis, M; Bergamaschi, R; Chinnaiyan, AM; Detre, T; Ezzat, S; Frilling, A; Hommann, M; Jaeger, D; Kim, MK; Knudsen, BS; Kung, AL; Leahy, E; Metz, DC; Milsom, JW; Park, YS; Reidy-Lagunes, D; Schreiber, S; Washington, K; Wiedenmann, B; Modlin, I; Califano, A
A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors.
Nat Genet. 2018; 50(7):979-989
Doi: 10.1038/s41588-018-0138-4
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Deshwar, A; Margonis, GA; Andreatos, N; Barbon, C; Wang, J; Buettner, S; Wagner, D; Sasaki, K; Beer, A; Løes, IM; Pikoulis, E; Damaskos, C; Garmpis, N; Kamphues, K; He, J; Kaczirek, K; Poultsides, G; Lønning, PE; Mischinger, HJ; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ
Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series.
Anticancer Res. 2018; 38(5):2891-2895
Doi: 10.21873/anticanres.12535
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El-Heliebi, A; Hille, C; Laxman, N; Svedlund, J; Haudum, C; Ercan, E; Kroneis, T; Chen, S; Smolle, M; Rossmann, C; Krzywkowski, T; Ahlford, A; Darai, E; von Amsberg, G; Alsdorf, W; König, F; Löhr, M; de Kruijff, I; Riethdorf, S; Gorges, TM; Pantel, K; Bauernhofer, T; Nilsson, M; Sedlmayr, P
In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells.
Clin Chem. 2018; 64(3):536-546
Doi: 10.1373/clinchem.2017.281295
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Fuchs, R; Stracke, A; Holzmann, V; Luschin-Ebengreuth, G; Meier-Allard, N; Ebner, N; Lassacher, TM; Absenger-Novak, M; Fröhlich, E; Schittmayer, M; Cano Crespo, S; Palacin, M; Rinner, B; Birner-Gruenberger, R
Prazosin induced lysosomal tubulation interferes with cytokinesis and the endocytic sorting of the tumour antigen CD98hc.
Biochim Biophys Acta Mol Cell Res. 2018; 1865(9):1211-1229
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Gandhi, L; Rodríguez-Abreu, D; Gadgeel, S; Esteban, E; Felip, E; De Angelis, F; Domine, M; Clingan, P; Hochmair, MJ; Powell, SF; Cheng, SY; Bischoff, HG; Peled, N; Grossi, F; Jennens, RR; Reck, M; Hui, R; Garon, EB; Boyer, M; Rubio-Viqueira, B; Novello, S; Kurata, T; Gray, JE; Vida, J; Wei, Z; Yang, J; Raftopoulos, H; Pietanza, MC; Garassino, MC; KEYNOTE-189 Investigators
Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.
N Engl J Med. 2018; 378(22): 2078-2092.
Doi: 10.1056/NEJMoa1801005
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Gantenbein, N; Bernhart, E; Anders, I; Golob-Schwarzl, N; Krassnig, S; Wodlej, C; Brcic, L; Lindenmann, J; Fink-Neuboeck, N; Gollowitsch, F; Stacher-Priehse, E; Asslaber, M; Gogg-Kamerer, M; Rolff, J; Hoffmann, J; Silvestri, A; Regenbrecht, C; Reinhard, C; Pehserl, AM; Pichler, M; Sokolova, O; Naumann, M; Mitterer, V; Pertschy, B; Bergler, H; Popper, H; Sattler, W; Haybaeck, J
Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression.
Eur J Cancer. 2018; 101(4):165-180
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Kindler, O; Quehenberger, F; Benesch, M; Seidel, MG
The Iceberg Map of germline mutations in childhood cancer: focus on primary immunodeficiencies.
Curr Opin Pediatr. 2018; 30(6):855-863
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Krstic, J; Reinisch, I; Schupp, M; Schulz, TJ; Prokesch, A
p53 Functions in Adipose Tissue Metabolism and Homeostasis.
Int J Mol Sci. 2018; 19(9):
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Li, M; Su, Y; Zhang, F; Chen, K; Xu, X; Xu, L; Zhou, J; Wang, W
A dual-targeting reconstituted high density lipoprotein leveraging the synergy of sorafenib and antimiRNA21 for enhanced hepatocellular carcinoma therapy.
Acta Biomater. 2018; 75(10):413-426
Doi: 10.1016/j.actbio.2018.05.049
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Li, M; Zhang, F; Su, Y; Zhou, J; Wang, W
Nanoparticles designed to regulate tumor microenvironment for cancer therapy.
Life Sci. 2018; 201(10):37-44
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Renner, W; Krenn-Pilko, S; Gruber, HJ; Herrmann, M; Langsenlehner, T
Relative telomere length and prostate cancer mortality.
Prostate Cancer Prostatic Dis. 2018; 21(4):579-583
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Saraggi, D; Salmaso, R; Zamuner, C; Munari, G; Lanza, C; Alaibac, MS; Bassetto, F; Rugge, M; Montesco, MC; Cerroni, L; Fassan, M
Prevalence of ALK gene alterations among the spectrum of plexiform spitzoid lesions.
J Am Acad Dermatol. 2018; 79(4):728-735
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Tsibulak, I; Wieser, V; Degasper, C; Shivalingaiah, G; Wenzel, S; Sprung, S; Lax, SF; Marth, C; Fiegl, H; Zeimet, AG
BRCA1 and BRCA2 mRNA-expression prove to be of clinical impact in ovarian cancer.
Br J Cancer. 2018; 119(6):683-692
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Zhong, Q; Wagner, U; Kurt, H; Molinari, F; Cathomas, G; Komminoth, P; Barman-Aksözen, J; Schneider-Yin, X; Rey, JP; Vassella, E; Rogel, U; Diebold, J; McKee, T; Jochum, W; Kashofer, K; Hofman, P; Zischka, M; Moch, H; Rechsteiner, M; Wild, PJ
Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing.
Pathol Res Pract. 2018; 214(7):957-963
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Amankulor, NM; Kim, Y; Arora, S; Kargl, J; Szulzewsky, F; Hanke, M; Margineantu, DH; Rao, A; Bolouri, H; Delrow, J; Hockenbery, D; Houghton, AM; Holland, EC
Mutant IDH1 regulates the tumor-associated immune system in gliomas.
Genes Dev. 2017; 31(8):774-786
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Arzt, L; Halbwedl, I; Gogg-Kamerer, M; Popper, HH
Signal Transducer and Activator of Transcription 1 (STAT1) Knock-down Induces Apoptosis in Malignant Pleural Mesothelioma.
Pathol Oncol Res. 2017; 23(3):595-605
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Asslaber, M; Schauer, S; Gogg-Kamerer, M; Bernhart, E; Quehenberger, F; Haybaeck, J
Native Oligodendrocytes in Astrocytomas Might Inhibit Tumor Proliferation by WIF1 Expression.
J Neuropathol Exp Neurol. 2017; 76(1):16-26
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Bayraktar, R; Pichler, M; Kanlikilicer, P; Ivan, C; Bayraktar, E; Kahraman, N; Aslan, B; Oguztuzun, S; Ulasli, M; Arslan, A; Calin, G; Lopez-Berestein, G; Ozpolat, B
MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase.
Oncotarget. 2017; 8(7): 11641-11658.
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Chen, S; El-Heliebi, A; Tauber, G; Langsenlehner, T; Pötscher, M; Kashofer, K; Czyż, ZT; Polzer, B; Riethdorf, S; Kuske, A; Leitinger, G; Pantel, K; Kroneis, T; Sedlmayr, P
Catch and Release: rare cell analysis from a functionalised medical wire.
Sci Rep. 2017; 7(2):43424-43424
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Cătană, CS; Pichler, M; Giannelli, G; Mader, RM; Berindan-Neagoe, I
Non-coding RNAs, the Trojan horse in two-way communication between tumor and stroma in colorectal and hepatocellular carcinoma.
Oncotarget. 2017; 8(17):29519-29534
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Cuppens, T; Annibali, D; Coosemans, A; Trovik, J; Ter Haar, N; Colas, E; Garcia-Jimenez, A; Van de Vijver, K; Kruitwagen, RP; Brinkhuis, M; Zikan, M; Dundr, P; Huvila, J; Carpén, O; Haybaeck, J; Moinfar, F; Salvesen, HB; Stukan, M; Mestdagh, C; Zweemer, RP; Massuger, LF; Mallmann, MR; Wardelmann, E; Mints, M; Verbist, G; Thomas, D; Gommé, E; Hermans, E; Moerman, P; Bosse, T; Amant, F
Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Clin Cancer Res. 2017; 23(5):1274-1285
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Dandachi, N; Tiran, V; Lindenmann, J; Brcic, L; Fink-Neuboeck, N; Kashofer, K; Absenger, G; Bezan, A; Cote, RJ; Datar, R; Balic, M
Frequency and clinical impact of preoperative circulating tumor cells in resectable non-metastatic lung adenocarcinomas.
Lung Cancer. 2017; 113(46):152-157
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El-Heliebi, A; Kashofer, K; Fuchs, J; Jahn, SW; Viertler, C; Matak, A; Sedlmayr, P; Hoefler, G
Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.
Histochem Cell Biol. 2017; 148(2):105-115
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Goblirsch, M; Richtig, G; Slaby, O; Berindan-Neagoe, I; Gerger, A; Pichler, M
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Gürtl-Lackner, B; Gisselsson-Nord, D; Vujanic, G
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Holch, JW; Metzeler, KH; Jung, A; Riedmann, K; Jost, PJ; Weichert, W; Kirchner, T; Heinemann, V; Westphalen, CB
Universal Genomic Testing: The next step in oncological decision-making or a dead end street?
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