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Publikationen

Suchbegriffe: NEOPLASMS - ENZYMOLOGY , . Treffer: 68

2020

Schwaab, J; Naumann, N; Luebke, J; Jawhar, M; Somervaille, TCP; Williams, MS; Frewin, R; Jost, PJ; Lichtenegger, FS; La Rosée, P; Storch, N; Haferlach, T; Horny, HP; Fabarius, A; Haferlach, C; Burchert, A; Hofmann, WK; Cross, NCP; Hochhaus, A; Reiter, A; Metzgeroth, G Response to tyrosine kinase inhibitors in myeloid neoplasms associated with PCM1-JAK2, BCR-JAK2 and ETV6-ABL1 fusion genes.
Am J Hematol. 2020; 95(7):824-833 Doi: 10.1002/ajh.25825 [OPEN ACCESS]
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2018

Davidson, B; Tötsch, M; Wohlschlaeger, J; Hager, T; Pinamonti, M The diagnostic role of BAP1 in serous effusions.
Hum Pathol. 2018; 79(6):122-126 Doi: 10.1016/j.humpath.2018.05.012
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2017

Amankulor, NM; Kim, Y; Arora, S; Kargl, J; Szulzewsky, F; Hanke, M; Margineantu, DH; Rao, A; Bolouri, H; Delrow, J; Hockenbery, D; Houghton, AM; Holland, EC Mutant IDH1 regulates the tumor-associated immune system in gliomas.
Genes Dev. 2017; 31(8):774-786 Doi: 10.1101/gad.294991.116 [OPEN ACCESS]
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Boege, Y; Malehmir, M; Healy, ME; Bettermann, K; Lorentzen, A; Vucur, M; Ahuja, AK; Böhm, F; Mertens, JC; Shimizu, Y; Frick, L; Remouchamps, C; Mutreja, K; Kähne, T; Sundaravinayagam, D; Wolf, MJ; Rehrauer, H; Koppe, C; Speicher, T; Padrissa-Altés, S; Maire, R; Schattenberg, JM; Jeong, JS; Liu, L; Zwirner, S; Boger, R; Hüser, N; Davis, RJ; Müllhaupt, B; Moch, H; Schulze-Bergkamen, H; Clavien, PA; Werner, S; Borsig, L; Luther, SA; Jost, PJ; Weinlich, R; Unger, K; Behrens, A; Hillert, L; Dillon, C; Di Virgilio, M; Wallach, D; Dejardin, E; Zender, L; Naumann, M; Walczak, H; Green, DR; Lopes, M; Lavrik, I; Luedde, T; Heikenwalder, M; Weber, A A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.
Cancer Cell. 2017; 32(3):342-359 Doi: 10.1016/j.ccell.2017.08.010 [OPEN ACCESS]
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Lienhart, WD; Strandback, E; Gudipati, V; Koch, K; Binter, A; Uhl, MK; Rantasa, DM; Bourgeois, B; Madl, T; Zangger, K; Gruber, K; Macheroux, P Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1).
FEBS J. 2017; 284(8):1233-1245 Doi: 10.1111/febs.14051 [OPEN ACCESS]
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Loibner, M; Oberauner-Wappis, L; Viertler, C; Groelz, D; Zatloukal, K Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation.
J Vis Exp. 2017; 8(130): Doi: 10.3791/55885 [OPEN ACCESS]
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2016

Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 Doi: 10.18632/oncotarget.9418 [OPEN ACCESS]
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Fan, P; Liu, L; Yin, Y; Zhao, Z; Zhang, Y; Amponsah, PS; Xiao, X; Bauer, N; Abukiwan, A; Nwaeburu, CC; Gladkich, J; Gao, C; Schemmer, P; Gross, W; Herr, I MicroRNA-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer.
Cancer Lett. 2016; 373(1):130-137 Doi: 10.1016/j.canlet.2016.01.038
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Li, Z; Yamada, S; Wu, Y; Wang, KY; Liu, YP; Uramoto, H; Kohno, K; Sasaguri, Y Polypeptide N-acetylgalactosaminyltransferase-6 expression independently predicts poor overall survival in patients with lung adenocarcinoma after curative resection.
Oncotarget. 2016; 7(34):54463-54473 Doi: 10.18632/oncotarget.9810 [OPEN ACCESS]
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2015

Dalpiaz, O; Pichler, M; Mrsic, E; Reitz, D; Krieger, D; Venturino, L; Bezan, A; Stojakovic, T; Pummer, K; Zigeuner, R; Hutterer, GC Preoperative serum-gamma-glutamyltransferase (GGT) does not represent an independent prognostic factor in a European cohort of patients with non-metastatic renal cell carcinoma.
J Clin Pathol. 2015; 68(7):547-551 Doi: 10.1136/jclinpath-2014-202683
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Didiasova, M; Zakrzewicz, D; Magdolen, V; Nagaraj, C; Bálint, Z; Rohde, M; Preissner, KT; Wygrecka, M STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization.
J Biol Chem. 2015; 290(19):11983-11999 Doi: 10.1074/jbc.M114.598425 [OPEN ACCESS]
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Rausch, S; Hennenlotter, J; Teepe, K; Kuehs, U; Aufderklamm, S; Bier, S; Mischinger, J; Gakis, G; Stenzl, A; Schwentner, C; Todenhöfer, T Muscle-invasive bladder cancer is characterized by overexpression of thymidine kinase 1.
Urol Oncol. 2015; 33(10):426.e21-426.e29 Doi: 10.1016/j.urolonc.2015.06.007
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Wiesner, T; Lee, W; Obenauf, AC; Ran, L; Murali, R; Zhang, QF; Wong, EW; Hu, W; Scott, SN; Shah, RH; Landa, I; Button, J; Lailler, N; Sboner, A; Gao, D; Murphy, DA; Cao, Z; Shukla, S; Hollmann, TJ; Wang, L; Borsu, L; Merghoub, T; Schwartz, GK; Postow, MA; Ariyan, CE; Fagin, JA; Zheng, D; Ladanyi, M; Busam, KJ; Berger, MF; Chen, Y; Chi, P Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Nature. 2015; 526(7573):453-457 Doi: 10.1038/nature15258 [OPEN ACCESS]
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2014

Busam, KJ; Kutzner, H; Cerroni, L; Wiesner, T Clinical and pathologic findings of Spitz nevi and atypical Spitz tumors with ALK fusions.
Am J Surg Pathol. 2014; 38(7):925-933 Doi: 10.1097/PAS.0000000000000187 [OPEN ACCESS]
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Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12): 2393-2403. Doi: 10.1111/jcmm.12412 [OPEN ACCESS]
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Kaushik, AK; Vareed, SK; Basu, S; Putluri, V; Putluri, N; Panzitt, K; Brennan, CA; Chinnaiyan, AM; Vergara, IA; Erho, N; Weigel, NL; Mitsiades, N; Shojaie, A; Palapattu, G; Michailidis, G; Sreekumar, A Metabolomic profiling identifies biochemical pathways associated with castration-resistant prostate cancer.
J Proteome Res. 2014; 13(2):1088-1100 Doi: 10.1021/pr401106h [OPEN ACCESS]
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Leithner, K; Wohlkoenig, C; Stacher, E; Lindenmann, J; Hofmann, NA; Gallé, B; Guelly, C; Quehenberger, F; Stiegler, P; Smolle-Jüttner, FM; Philipsen, S; Popper, HH; Hrzenjak, A; Olschewski, A; Olschewski, H Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model - role of tumor stroma cells.
BMC Cancer. 2014; 14(1):40-40 Doi: 10.1186/1471-2407-14-40 [OPEN ACCESS]
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2013

Mairinger, F; Vollbrecht, C; Halbwedl, I; Hatz, M; Stacher, E; Gülly, C; Quehenberger, F; Stephan-Falkenau, S; Kollmeier, J; Roth, A; Mairinger, T; Popper, H Reduced folate carrier and folylpolyglutamate synthetase, but not thymidylate synthase predict survival in pemetrexed-treated patients suffering from malignant pleural mesothelioma.
J Thorac Oncol. 2013; 8(5):644-653 Doi: 10.1097/JTO.0b013e318287c224 [OPEN ACCESS]
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Partl, R; Richtig, E; Avian, A; Berghold, A; Kapp, KS Karnofsky performance status and lactate dehydrogenase predict the benefit of palliative whole-brain irradiation in patients with advanced intra- and extracranial metastases from malignant melanoma.
Int J Radiat Oncol Biol Phys. 2013; 85(3):662-666 Doi: 10.1016/j.ijrobp.2012.06.009
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Watzka, SB; Posch, F; Pass, HI; Flores, RM; Hannigan, GE; Bernhard, D; Weber, M; Mueller, MR Serum concentration of integrin-linked kinase in malignant pleural mesothelioma and after asbestos exposure.
Eur J Cardiothorac Surg. 2013; 43(5):940-945 Doi: 10.1093/ejcts/ezs521 [OPEN ACCESS]
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2012

Froehlich, EV; Scheipl, S; Lazary, A; Varga, PP; Schmid, C; Stammberger, H; Beham, A; Bodo, K; Schroettner, H; Quehenberger, F; Windhager, R; Liegl, B; Leithner, A Expression of Ezrin, MMP-9, and COX-2 in 50 Chordoma Specimens: A Clinical and Immunohistochemical Analysis.
Spine (Phila Pa 1976). 2012; 37(13):E757-E767 Doi: 10.1097/BRS.0b013e31824782e1
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Hafner, C; Houben, R; Baeurle, A; Ritter, C; Schrama, D; Landthaler, M; Becker, JC Activation of the PI3K/AKT pathway in Merkel cell carcinoma.
PLoS One. 2012; 7(2):e31255-e31255 Doi: 10.1371/journal.pone.0031255 [OPEN ACCESS]
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Lajin, B; Alhaj Sakur, A; Ghabreau, L; Alachkar, A Association of polymorphisms in one-carbon metabolizing genes with breast cancer risk in Syrian women.
Tumour Biol. 2012; 33(4):1133-1139 Doi: 10.1007/s13277-012-0354-y
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2011

Das, SK; Eder, S; Schauer, S; Diwoky, C; Temmel, H; Guertl, B; Gorkiewicz, G; Tamilarasan, KP; Kumari, P; Trauner, M; Zimmermann, R; Vesely, P; Haemmerle, G; Zechner, R; Hoefler, G Adipose triglyceride lipase contributes to cancer-associated cachexia.
Science. 2011; 333(6039):233-238 Doi: 10.1126/science.1198973 [OPEN ACCESS]
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Fröhlich, E; Engel, E; Wahl, R Decrease in dipeptidyl peptidase IV activity is linked to the efficacy of differentiating compounds in follicular thyroid carcinoma cell lines.
HORMONE METAB RES. 2011; 43(5): 364-366. Doi: 10.1055/s-0031-1273682 [OPEN ACCESS]
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Lill, C; Schneider, S; Pammer, J; Loewe, R; Gedlicka, W; Houben, R; Heiduschka, G; Brunner, M; Thurnher, D Significant correlation of peptidyl-prolyl isomerase overexpression in Merkel cell carcinoma with overall survival of patients.
Head Neck. 2011; 33(9):1294-1300 Doi: 10.1002/hed.21596
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Watzka, SB; Posch, F; Pass, HI; Huflejt, M; Bernhard, D; Hannigan, GE; Müller, MR Detection of integrin-linked kinase in the serum of patients with malignant pleural mesothelioma.
J Thorac Cardiovasc Surg. 2011; 142(2):384-389 Doi: 10.1016/j.jtcvs.2011.04.034 [OPEN ACCESS]
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2010

Fröhlich, E Proteases in cutaneous malignant melanoma: relevance as biomarker and therapeutic target.
Cell Mol Life Sci. 2010; 67(23): 3947-3960. Doi: 10.1007/s00018-010-0469-5
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Frohlich, E; Kueznik, T; Samberger, C; Roblegg, E; Wrighton, C; Pieber, TR Size-dependent effects of nanoparticles on the activity of cytochrome P450 isoenzymes.
TOXICOL APPL PHARMACOL. 2010; 242(3): 326-332. Doi: 10.1016/j.taap.2009.11.002
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Grimm, M; Lazariotou, M; Kircher, S; Stuermer, L; Reiber, C; Höfelmayr, A; Gattenlöhner, S; Otto, C; Germer, CT; von Rahden, BH MMP-1 is a (pre-)invasive factor in Barrett-associated esophageal adenocarcinomas and is associated with positive lymph node status.
J Transl Med. 2010; 8(1):99-99 Doi: 10.1186/1479-5876-8-99 [OPEN ACCESS]
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Hrzenjak, A; Moinfar, F; Kremser, ML; Strohmeier, B; Petru, E; Zatloukal, K; Denk, H Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo.
Mol Cancer. 2010; 9(10): 49-49. Doi: 10.1186/1476-4598-9-49 [OPEN ACCESS]
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Pau, M; Beham-Schmid, C; Zemann, W; Kahr, H; Karcher, H Intraoral Granulocytic Sarcoma: A Case Report and Review of the Literature
J ORAL MAXILLOFAC SURG. 2010; 68(10): 2569-2574. Doi: 10.1016/j.joms.2009.09.040 (- Case Report)
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Vucur, M; Roderburg, C; Bettermann, K; Tacke, F; Heikenwalder, M; Trautwein, C; Luedde, T Mouse models of hepatocarcinogenesis: what can we learn for the prevention of human hepatocellular carcinoma?
Oncotarget. 2010; 1(5):373-378 Doi: 10.18632/oncotarget.170 [OPEN ACCESS]
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2009

Heiduschka, G; Erovic, BM; Vormittag, L; Skoda, C; Martinek, H; Brunner, M; Ehrenberger, K; Thurnher, D 7beta-hydroxycholesterol induces apoptosis and regulates cyclooxygenase 2 in head and neck squamous cell carcinoma.
Arch Otolaryngol Head Neck Surg. 2009; 135(3):261-267 Doi: 10.1001/archoto.2008.558
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Krejsgaard, T; Vetter-Kauczok, CS; Woetmann, A; Kneitz, H; Eriksen, KW; Lovato, P; Zhang, Q; Wasik, MA; Geisler, C; Ralfkiaer, E; Becker, JC; Odum, N Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma.
Blood. 2009; 113(23):5896-5904 Doi: 10.1182/blood-2008-09-181024 [OPEN ACCESS]
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2008

Erovic, BM; Woegerbauer, M; Pammer, J; Selzer, E; Grasl, MCh; Thurnher, D Strong evidence for up-regulation of cyclooxygenase-1 in head and neck cancer.
Eur J Clin Invest. 2008; 38(1):61-66 Doi: 10.1111/j.1365-2362.2007.01896.x
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Stadler, G; Wieser, M; Streubel, B; Stift, A; Friedl, J; Gnant, M; Niederle, B; Beham, A; Katinger, H; Pfragner, R; Grillari, J; Voglauer, R Low telomerase activity: possible role in the progression of human medullary thyroid carcinoma.
Eur J Cancer. 2008; 44(6): 866-875. Doi: 10.1016/j.ejca.2007.12.014 [OPEN ACCESS]
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2007

Agic, A; Xu, H; Altgassen, C; Noack, F; Wolfler, MM; Diedrich, K; Friedrich, M; Taylor, RN; Hornung, D Relative expression of 1,25-dihydroxyvitamin D3 receptor, vitamin D 1 alpha-hydroxylase, vitamin D 24-hydroxylase, and vitamin D 25-hydroxylase in endometriosis and gynecologic cancers.
Reprod Sci. 2007; 14(5): 486-497. Doi: 10.1177/1933719107304565
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Houben, R; Ortmann, S; Schrama, D; Herold, MJ; Berberich, I; Reichardt, HM; Becker, JC Activation of the MAP kinase pathway induces apoptosis in the Merkel cell carcinoma cell line UISO.
J Invest Dermatol. 2007; 127(9):2116-2122 Doi: 10.1038/sj.jid.5700857 [OPEN ACCESS]
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Reich, O; Singer, C; Hudelist, G; Regauer, S Estrogen sulfotransferase expression in endometrial stromal sarcomas: an immunohistochemical study.
PATHOL RES PRACT. 2007; 203(2): 85-87. Doi: 10.1016/j.prp.2006.10.003
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2006

Hrzenjak, A; Moinfar, F; Kremser, ML; Strohmeier, B; Staber, PB; Zatloukal, K; Denk, H Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells.
Mol Cancer Ther. 2006; 5(9):2203-2210 Doi: 10.1158/1535-7163.MCT-05-0480 [OPEN ACCESS]
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Langner, C; Rupar, G; Leibl, S; Hutterer, G; Chromecki, T; Hoefler, G; Rehak, P; Zigeuner, R Alpha-methylacyl-CoA racemase (AMACR/P504S) protein expression in urothelial carcinoma of the upper urinary tract correlates with tumour progression.
Virchows Arch. 2006; 448(3):325-330 Doi: 10.1007/s00428-005-0129-6
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Regauer, S; Beham-Schmid, C Thymidylate synthase overexpression in extramammary Paget's disease.
HISTOPATHOLOGY 2006 48: 870-872. Doi: 10.1111/j.1365-2559.2006.02426.x
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2005

Andersen, MH; Becker, JC; Straten, PT The antiapoptotic member of the Bcl-2 family Mcl-1 is a CTL target in cancer patients.
Leukemia. 2005; 19(3):484-485 Doi: 10.1038/sj.leu.2403621 [OPEN ACCESS]
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Andersen, MH; Reker, S; Kvistborg, P; Becker, JC; Straten, PT Spontaneous immunity against Bcl-xL in cancer patients.
J Immunol. 2005; 175(4):2709-2714 Doi: 10.4049/jimmunol.175.4.2709 [OPEN ACCESS]
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Hofmann, UB; Eggert, AAO; Blass, K; Brocker, EB; Becker, JC Stromal cells as the major source for matrix metalloproteinase-2 in cutaneous melanoma.
Arch Dermatol Res. 2005; 297(4):154-160 Doi: 10.1007/s00403-005-0588-2
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Ugurel, S; Bell, N; Sucker, A; Zimpfer, A; Rittgen, W; Schadendorf, D Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma.
Int J Cancer. 2005; 117(5):825-830 Doi: 10.1002/ijc.21073
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2004

Fröhlich, E; Möhrle, M; Klessen, C Cathepsins in basal cell carcinomas: activity, immunoreactivity and mRNA staining of cathepsins B, D, H and L.
Arch Dermatol Res. 2004; 295(10):411-421 Doi: 10.1007/s00403-003-0449-9
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Pelzmann, M; Thurnher, D; Gedlicka, C; Martinek, H; Knerer, B Nimesulide and indomethacin induce apoptosis in head and neck cancer cells.
J Oral Pathol Med. 2004; 33(10):607-613 Doi: 10.1111/j.1600-0714.2004.00216.x
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Reich, O; Regauer, S Aromatase expression in low-grade endometrial stromal sarcomas: an immunohistochemical study.
Mod Pathol. 2004; 17(1):104-108 Doi: 10.1038/sj.modpathol.3800031 [OPEN ACCESS]
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