Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: NEOPLASM PROTEINS - METABOLISM, . Treffer: 77

2023

Maltan, L; Weiß, S; Najjar, H; Leopold, M; Lindinger, S; Höglinger, C; Höbarth, L; Sallinger, M; Grabmayr, H; Berlansky, S; Krivic, D; Hopl, V; Blaimschein, A; Fahrner, M; Frischauf, I; Tiffner, A; Derler, I Photocrosslinking-induced CRAC channel-like Orai1 activation independent of STIM1.
Nat Commun. 2023; 14(1): 1286 Doi: 10.1038/s41467-023-36458-4 [OPEN ACCESS]
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2019

Egger, M; Maier, E; Robier, C Light chain myeloma with bar-shaped intranuclear kappa light chain inclusions.
Ann Hematol. 2019; 98(9):2237-2238 Doi: 10.1007/s00277-019-03718-7 (- Case Report)
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Schober, R; Bonhenry, D; Lunz, V; Zhu, J; Krizova, A; Frischauf, I; Fahrner, M; Zhang, M; Waldherr, L; Schmidt, T; Derler, I; Stathopulos, PB; Romanin, C; Ettrich, RH; Schindl, R Sequential activation of STIM1 links Ca2+ with luminal domain unfolding.
Sci Signal. 2019; 12(608): Doi: 10.1126/scisignal.aax3194
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Stumptner, C; Pabst, D; Loibner, M; Viertler, C; Zatloukal, K The impact of crosslinking and non-crosslinking fixatives on antigen retrieval and immunohistochemistry.
N Biotechnol. 2019; 52:69-83 Doi: 10.1016/j.nbt.2019.05.003
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2017

Frischauf, I; Litviňuková, M; Schober, R; Zayats, V; Svobodová, B; Bonhenry, D; Lunz, V; Cappello, S; Tociu, L; Reha, D; Stallinger, A; Hochreiter, A; Pammer, T; Butorac, C; Muik, M; Groschner, K; Bogeski, I; Ettrich, RH; Romanin, C; Schindl, R Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
Sci Signal. 2017; 10(507): Doi: 10.1126/scisignal.aao0358 [OPEN ACCESS]
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Geuens, T; De Winter, V; Rajan, N; Achsel, T; Mateiu, L; Almeida-Souza, L; Asselbergh, B; Bouhy, D; Auer-Grumbach, M; Bagni, C; Timmerman, V Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease.
Acta Neuropathol Commun. 2017; 5(1):5-5 Doi: 10.1186/s40478-016-0407-3 [OPEN ACCESS]
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Lin, S; Hoffmann, K; Gao, C; Petrulionis, M; Herr, I; Schemmer, P Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma.
J PINEAL RES. 2017; 62(3): Doi: 10.1111/jpi.12398
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Szurian, K; Till, H; Amerstorfer, E; Hinteregger, N; Mischinger, HJ; Liegl-Atzwanger, B; Brcic, I Rarity among benign gastric tumors: Plexiform fibromyxoma - Report of two cases.
World J Gastroenterol. 2017; 23(31):5817-5822 Doi: 10.3748/wjg.v23.i31.5817 (- Case Report) [OPEN ACCESS]
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2016

Harada, Y; Izumi, H; Noguchi, H; Kuma, A; Kawatsu, Y; Kimura, T; Kitada, S; Uramoto, H; Wang, KY; Sasaguri, Y; Hijioka, H; Miyawaki, A; Oya, R; Nakayama, T; Kohno, K; Yamada, S Strong expression of polypeptide N-acetylgalactosaminyltransferase 3 independently predicts shortened disease-free survival in patients with early stage oral squamous cell carcinoma.
Tumour Biol. 2016; 37(1):1357-1368 Doi: 10.1007/s13277-015-3928-7 [OPEN ACCESS]
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Rausch, S; Hennenlotter, J; Scharpf, M; Teepe, K; Kühs, U; Aufderklamm, S; Bier, S; Mischinger, J; Gakis, G; Stenzl, A; Schwentner, C; Todenhöfer, T Prostate tumor overexpressed 1 expression in invasive urothelial carcinoma.
J Cancer Res Clin Oncol. 2016; 142(5):937-947 Doi: 10.1007/s00432-015-2107-y
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2015

Didiasova, M; Zakrzewicz, D; Magdolen, V; Nagaraj, C; Bálint, Z; Rohde, M; Preissner, KT; Wygrecka, M STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization.
J Biol Chem. 2015; 290(19):11983-11999 Doi: 10.1074/jbc.M114.598425 [OPEN ACCESS]
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Li, C; Rezania, S; Kammerer, S; Sokolowski, A; Devaney, T; Gorischek, A; Jahn, S; Hackl, H; Groschner, K; Windpassinger, C; Malle, E; Bauernhofer, T; Schreibmayer, W Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line.
Sci Rep. 2015; 5(2):8364-8364 Doi: 10.1038/srep08364 [OPEN ACCESS]
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Stotz, M; Gerger, A; Haybaeck, J; Kiesslich, T; Bullock, MD; Pichler, M Molecular Targeted Therapies in Hepatocellular Carcinoma: Past, Present and Future.
Anticancer Res. 2015; 35(11):5737-5744
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2014

Deak, AT; Blass, S; Khan, MJ; Groschner, LN; Waldeck-Weiermair, M; Hallström, S; Graier, WF; Malli, R IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake.
J Cell Sci. 2014; 127(Pt 13):2944-2955 Doi: 10.1242/jcs.149807 [OPEN ACCESS]
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Fahrner, M; Muik, M; Schindl, R; Butorac, C; Stathopulos, P; Zheng, L; Jardin, I; Ikura, M; Romanin, C A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).
J Biol Chem. 2014; 289(48): 33231-33244. Doi: 10.1074/jbc.M114.610022 [OPEN ACCESS]
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Krstic, J; Santibanez, JF Transforming growth factor-beta and matrix metalloproteinases: functional interactions in tumor stroma-infiltrating myeloid cells.
ScientificWorldJournal. 2014; 2014(3): 521754-521754. Doi: 10.1155/2014/521754 [OPEN ACCESS]
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2013

Deak, AT; Groschner, LN; Alam, MR; Seles, E; Bondarenko, AI; Graier, WF; Malli, R The endocannabinoid N-arachidonoyl glycine (NAGly) inhibits store-operated Ca2+ entry by preventing STIM1-Orai1 interaction.
J Cell Sci. 2013; 126(Pt 4):879-888 Doi: 10.1242/jcs.118075 [OPEN ACCESS]
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Derler, I; Plenk, P; Fahrner, M; Muik, M; Jardin, I; Schindl, R; Gruber, HJ; Groschner, K; Romanin, C The extended transmembrane Orai1 N-terminal (ETON) region combines binding interface and gate for Orai1 activation by STIM1.
J Biol Chem. 2013; 288(40):29025-29034 Doi: 10.1074/jbc.M113.501510 [OPEN ACCESS]
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Derler, I; Schindl, R; Fritsch, R; Heftberger, P; Riedl, MC; Begg, M; House, D; Romanin, C The action of selective CRAC channel blockers is affected by the Orai pore geometry.
Cell Calcium. 2013; 53(2): 139-151. Doi: 10.1016/j.ceca.2012.11.005 [OPEN ACCESS]
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Sbiera, S; Kroiss, M; Thamm, T; Beyer, M; Majidi, F; Kuehner, D; Wobser, M; Becker, JC; Adam, P; Ronchi, C; Allolio, B; Fassnacht, M; Survivin in Adrenocortical Tumors Pathophysiological Implications and Therapeutic Potential.
HORMONE METAB RES. 2013; 45(2): 137-146. Doi: 10.1055/s-0032-1327750 [OPEN ACCESS]
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Stathopulos, PB; Schindl, R; Fahrner, M; Zheng, L; Gasmi-Seabrook, GM; Muik, M; Romanin, C; Ikura, M STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry.
Nat Commun. 2013; 4(48): 2963-2963. Doi: 10.1038/ncomms3963 [OPEN ACCESS]
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van Oosterwijk, JG; Meijer, D; van Ruler, MA; van den Akker, BE; Oosting, J; Krenács, T; Picci, P; Flanagan, AM; Liegl-Atzwanger, B; Leithner, A; Athanasou, N; Daugaard, S; Hogendoorn, PC; Bovée, JV Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.
Am J Pathol. 2013; 182(4):1347-1356 Doi: 10.1016/j.ajpath.2012.12.036 [OPEN ACCESS]
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2012

Kretschmer, N; Rinner, B; Stuendl, N; Kaltenegger, H; Wolf, E; Kunert, O; Boechzelt, H; Leithner, A; Bauer, R; Lohberger, B Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and ABC transporter expression in human soft tissue sarcoma cells.
Planta Med. 2012; 78(16):1749-1756 Doi: 10.1055/s-0032-1315385 [OPEN ACCESS]
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Muik, M; Schindl, R; Fahrner, M; Romanin, C Ca(2+) release-activated Ca(2+) (CRAC) current, structure, and function.
Cell Mol Life Sci. 2012; 69(24): 4163-4176. Doi: 10.1007/s00018-012-1072-8 [OPEN ACCESS]
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Shirsath, NP; Manohar, SM; Joshi, KS P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines.
Mol Cancer. 2012; 11:77-77 Doi: 10.1186/1476-4598-11-77 [OPEN ACCESS]
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2011

Bergsmann, J; Derler, I; Muik, M; Frischauf, I; Fahrner, M; Pollheimer, P; Schwarzinger, C; Gruber, HJ; Groschner, K; Romanin, C Molecular determinants within N terminus of Orai3 protein that control channel activation and gating.
J Biol Chem. 2011; 286(36): 31565-31575. Doi: 10.1074/jbc.M111.227546 [OPEN ACCESS]
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Drozdov, I; Svejda, B; Gustafsson, BI; Mane, S; Pfragner, R; Kidd, M; Modlin, IM Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia.
PLoS One. 2011; 6(8):e22457-e22457 Doi: 10.1371/journal.pone.0022457 [OPEN ACCESS]
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Gugatschka, M; Kojima, T; Ohno, S; Kanemaru, S; Hirano, S Recruitment patterns of side population cells during wound healing in rat vocal folds.
Laryngoscope. 2011; 121(8):1662-1667 Doi: 10.1002/lary.21817
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Muik, M; Fahrner, M; Schindl, R; Stathopulos, P; Frischauf, I; Derler, I; Plenk, P; Lackner, B; Groschner, K; Ikura, M; Romanin, C STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation.
EMBO J. 2011; 30(9): 1678-1689. Doi: 10.1038/emboj.2011.79 [OPEN ACCESS]
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Petry, KU; Schmidt, D; Scherbring, S; Luyten, A; Reinecke-Lüthge, A; Bergeron, C; Kommoss, F; Löning, T; Ordi, J; Regauer, S; Ridder, R Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16/Ki-67 Dual-stained cytology.
Gynecol Oncol. 2011; 121(3):505-509 Doi: 10.1016/j.ygyno.2011.02.033
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Shalaby, A; Presneau, N; Ye, H; Halai, D; Berisha, F; Idowu, B; Leithner, A; Liegl, B; Briggs, TR; Bacsi, K; Kindblom, LG; Athanasou, N; Amary, MF; Hogendoorn, PC; Tirabosco, R; Flanagan, AM The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target.
J Pathol. 2011; 223(3): 336-346. Doi: 10.1002/path.2818
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Zheng, L; Stathopulos, PB; Schindl, R; Li, GY; Romanin, C; Ikura, M Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry.
Proc Natl Acad Sci U S A. 2011; 108(4): 1337-1342. Doi: 10.1073/pnas.1015125108 [OPEN ACCESS]
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2010

Houben, R; Schrama, D; Alb, M; Pfohler, C; Trefzer, U; Ugurel, S; Becker, JC Comparable expression and phosphorylation of the retinoblastoma protein in Merkel cell polyoma virus-positive and negative Merkel cell carcinoma.
Int J Cancer. 2010; 126(3):796-798 Doi: 10.1002/ijc.24790 [OPEN ACCESS]
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Naghdi, S; Waideck-Weiermair, M; Fertschai, I; Poteser, M; Graier, WF; Malli, R Mitochondrial Ca2+ uptake and not mitochondrial motility is required for STIM1-Orai1-dependent store-operated Ca2+ entry.
J CELL SCI. 2010; 123(Pt 15): 2553-2564. Doi: 10.1242/jcs.070151 [OPEN ACCESS]
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Ubaida Mohien, C; Hartler, J; Breitwieser, F; Rix, U; Remsing Rix, L; Winter, GE; Thallinger, GG; Bennett, KL; Superti-Furga, G; Trajanoski, Z; Colinge, J MASPECTRAS 2: An integration and analysis platform for proteomic data.
Proteomics. 2010; 10(14):2719-2722 Doi: 10.1002/pmic.201000075
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2009

Derler, I; Fahrner, M; Muik, M; Lackner, B; Schindl, R; Groschner, K; Romanin, C A Ca2(+ )release-activated Ca2(+) (CRAC) modulatory domain (CMD) within STIM1 mediates fast Ca2(+)-dependent inactivation of ORAI1 channels.
J Biol Chem. 2009; 284(37): 24933-24938. Doi: 10.1074/jbc.C109.024083 [OPEN ACCESS]
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Gadjanski, I; Boretius, S; Williams, SK; Lingor, P; Knöferle, J; Sättler, MB; Fairless, R; Hochmeister, S; Sühs, KW; Michaelis, T; Frahm, J; Storch, MK; Bähr, M; Diem, R Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis.
Ann Neurol. 2009; 66(1): 81-93. Doi: 10.1002/ana.21668 [OPEN ACCESS]
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Gutwein, P; Schramme, A; Sinke, N; Abdel-Bakky, MS; Voss, B; Obermüller, N; Doberstein, K; Koziolek, M; Fritzsche, F; Johannsen, M; Jung, K; Schaider, H; Altevogt, P; Ludwig, A; Pfeilschifter, J; Kristiansen, G Tumoural CXCL16 expression is a novel prognostic marker of longer survival times in renal cell cancer patients.
Eur J Cancer. 2009; 45(3): 478-489. Doi: 10.1016/j.ejca.2008.10.023
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Leinweber, B; Hofmann-Wellenhof, R; Kaddu, S; McCalmont, TH Procollagen 1 and Melan-A expression in desmoplastic melanomas.
Am J Dermatopathol. 2009; 31(2):173-176 Doi: 10.1097/DAD.0b013e3181930b85
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Muik, M; Fahrner, M; Derler, I; Schindl, R; Bergsmann, J; Frischauf, I; Groschner, K; Romanin, C A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels.
J Biol Chem. 2009; 284(13):8421-8426 Doi: 10.1074/jbc.C800229200 [OPEN ACCESS]
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Schindl, R; Muik, M; Fahrner, M; Derler, I; Fritsch, R; Bergsmann, J; Romanin, C Recent progress on STIM1 domains controlling Orai activation.
Cell Calcium. 2009; 46(4): 227-232. Doi: 10.1016/j.ceca.2009.08.003
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Suzuki, R; Nourani, MR; Saino-Saito, S; Abe, H; Nochi, T; Kiyono, H; Spener, F; Kondo, H; Owada, Y Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine.
Histochem Cell Biol. 2009; 132(6):577-584 Doi: 10.1007/s00418-009-0638-5
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Vermi, W; Lonardi, S; Morassi, M; Rossini, C; Tardanico, R; Venturini, M; Sala, R; Tincani, A; Poliani, PL; Calzavara-Pinton, PG; Cerroni, L; Santoro, A; Facchetti, F Cutaneous distribution of plasmacytoid dendritic cells in lupus erythematosus. Selective tropism at the site of epithelial apoptotic damage.
Immunobiology. 2009; 214(9-10): 877-886. Doi: 10.1016/j.imbio.2009.06.013
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Vormittag, L; Thurnher, D; Geleff, S; Pammer, J; Heiduschka, G; Brunner, M; Grasl, MCh; Erovic, BM Co-expression of Bmi-1 and podoplanin predicts overall survival in patients with squamous cell carcinoma of the head and neck treated with radio(chemo)therapy.
Int J Radiat Oncol Biol Phys. 2009; 73(3):913-918 Doi: 10.1016/j.ijrobp.2008.10.040
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2008

Brunner, M; Thurnher, D; Pammer, J; Geleff, S; Heiduschka, G; Reinisch, CM; Petzelbauer, P; Erovic, BM Expression of VEGF-A/C, VEGF-R2, PDGF-alpha/beta, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma.
Mod Pathol. 2008; 21(7):876-884 Doi: 10.1038/modpathol.2008.63 [OPEN ACCESS]
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Frischauf, I; Schindl, R; Derler, I; Bergsmann, J; Fahrner, M; Romanin, C The STIM/Orai coupling machinery.
Channels (Austin). 2008; 2(4): 261-268. Doi: 10.4161/chan.2.4.6705 [OPEN ACCESS]
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Kothmaier, H; Quehenberger, F; Halbwedl, I; Morbini, P; Demirag, F; Zeren, H; Comin, CE; Murer, B; Cagle, PT; Attanoos, R; Gibbs, AR; Gallateau-Salle, F; Popper, HH EGFR and PDGFR differentially promote growth in malignant epithelioid mesothelioma of short and long term survivors.
Thorax. 2008; 63(4):345-351 Doi: 10.1136/thx.2007.085241 [OPEN ACCESS]
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Muik, M; Frischauf, I; Derler, I; Fahrner, M; Bergsmann, J; Eder, P; Schindl, R; Hesch, C; Polzinger, B; Fritsch, R; Kahr, H; Madl, J; Gruber, H; Groschner, K; Romanin, C Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.
J Biol Chem. 2008; 283(12):8014-8022 Doi: 10.1074/jbc.M708898200 [OPEN ACCESS]
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Popper, HH; Kothmaier, H Proteomics-Tissue and Protein Microarrays and Antibody Array What Information Is Provided?
ARCH PATHOL LAB MED. 2008; 132(10):1570-1572.-21st European Congress of Pathology; SEP 08-13, 2007; Istanbul, TURKEY. Doi: 10.5858/2008-132-1570-PAPMAA [Oral Communication] [OPEN ACCESS]
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Schindl, R; Bergsmann, J; Frischauf, I; Derler, I; Fahrner, M; Muik, M; Fritsch, R; Groschner, K; Romanin, C 2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size.
J Biol Chem. 2008; 283(29):20261-20267 Doi: 10.1074/jbc.M803101200 [OPEN ACCESS]
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