Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: NAFLD, . Treffer: 51

2020

Craciun, A; Lackner, C; Cortez-Pinto, H Nonalcoholic Fatty Liver Disease versus Alcohol-related Liver Disease: Is it Really so Different?
CURR PHARM DESIGN. 2020; 26(10): 1093-1109.
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Mörwald, K; Aigner, E; Bergsten, P; Brunner, SM; Forslund, A; Kullberg, J; Ahlström, H; Manell, H; Roomp, K; Schütz, S; Zsoldos, F; Renner, W; Furthner, D; Maruszczak, K; Zandanell, S; Weghuber, D; Mangge, H Serum Ferritin Correlates With Liver Fat in Male Adolescents With Obesity.
Front Endocrinol (Lausanne). 2020; 11: 340-340. [OPEN ACCESS]
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Nardo, AD; Grün, NG; Zeyda, M; Dumanic, M; Oberhuber, G; Rivelles, E; Helbich, TH; Markgraf, DF; Roden, M; Claudel, T; Trauner, M; Stulnig, TM Impact of osteopontin on the development of non-alcoholic liver disease and related hepatocellular carcinoma.
Liver Int. 2020; 40(7):1620-1633 [OPEN ACCESS]
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Safari, Z; Bruneau, A; Monnoye, M; Mariadassou, M; Philippe, C; Zatloukal, K; Gerard, P Murine Genetic Background Overcomes Gut Microbiota Changes to Explain Metabolic Response to High-Fat Diet
NUTRIENTS. 2020; 12(2): 287 [OPEN ACCESS]
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2019

Kaltenecker, D; Themanns, M; Mueller, KM; Spirk, K; Suske, T; Merkel, O; Kenner, L; Luís, A; Kozlov, A; Haybaeck, J; Müller, M; Han, X; Moriggl, R Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression.
Cytokine. 2018; 154569-154569 [OPEN ACCESS]
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Lackner, C; Tiniakos, D Fibrosis and alcohol-related liver disease.
J HEPATOL. 2019; 70(2): 294-304.
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Maresch, LK; Benedikt, P; Feiler, U; Eder, S; Zierler, KA; Taschler, U; Kolleritsch, S; Eichmann, TO; Schoiswohl, G; Leopold, C; Wieser, BI; Lackner, C; Rülicke, T; van Klinken, J; Kratky, D; Moustafa, T; Hoefler, G; Haemmerle, G Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.
Hepatol Commun. 2019; 3(2): 227-245. [OPEN ACCESS]
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Safari, Z; Gérard, P The links between the gut microbiome and non-alcoholic fatty liver disease (NAFLD).
Cell Mol Life Sci. 2019; 76(8):1541-1558
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Safari, Z; Monnoye, M; Abuja, PM; Mariadassou, M; Kashofer, K; Gérard, P; Zatloukal, K Steatosis and gut microbiota dysbiosis induced by high-fat diet are reversed by 1-week chow diet administration.
Nutr Res. 2019; 71: 72-88.
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Staufer, K; Halilbasic, E; Spindelboeck, W; Eilenberg, M; Prager, G; Stadlbauer, V; Posch, A; Munda, P; Marculescu, R; Obermayer-Pietsch, B; Stift, J; Lackner, C; Trauner, M; Stauber, RE Evaluation and comparison of six noninvasive tests for prediction of significant or advanced fibrosis in nonalcoholic fatty liver disease
UNITED EUR GASTROENT. 2019; UNSP 2050640619865133 [OPEN ACCESS]
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2018

Argo, CK; Stine, JG; Henry, ZH; Lackner, C; Patrie, JT; Weltman, AL; Caldwell, SH Physical deconditioning is the common denominator in both obese and overweight subjects with nonalcoholic steatohepatitis.
Aliment Pharmacol Ther. 2018; 48(3): 290-299. [OPEN ACCESS]
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Denkmayr, L; Feldman, A; Stechemesser, L; Eder, SK; Zandanell, S; Schranz, M; Strasser, M; Huber-Schönauer, U; Buch, S; Hampe, J; Paulweber, B; Lackner, C; Haufe, H; Sotlar, K; Datz, C; Aigner, E Lean Patients with Non-Alcoholic Fatty Liver Disease Have a Severe Histological Phenotype Similar to Obese Patients.
J Clin Med. 2018; 7(12): [OPEN ACCESS]
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Graffmann, N; Bohndorf, M; Ncube, A; Kawala, MA; Wruck, W; Kashofer, K; Zatloukal, K; Adjaye, J Establishment and characterization of an iPSC line from a 35 years old high grade patient with nonalcoholic fatty liver disease (30-40% steatosis) with homozygous wildtype PNPLA3 genotype.
Stem Cell Res. 2018; 31: 113-116. [OPEN ACCESS]
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Graffmann, N; Bohndorf, M; Ncube, A; Wruck, W; Kashofer, K; Zatloukal, K; Adjaye, J Establishment and characterization of an iPSC line from a 58 years old high grade patient with nonalcoholic fatty liver disease (70% steatosis) with homozygous wildtype PNPLA3 genotype.
Stem Cell Res. 2018; 31(4):131-134 (- Case Report) [OPEN ACCESS]
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Nobili, V; Alisi, A; Mosca, A; Della Corte, C; Veraldi, S; De Vito, R; De Stefanis, C; D'Oria, V; Jahnel, J; Zohrer, E; Scorletti, E; Byrne, CD Hepatic farnesoid X receptor protein level and circulating fibroblast growth factor 19 concentration in children with NAFLD.
Liver Int. 2018; 38(2):342-349
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2017

Caldwell, S; Lackner, C Perspectives on NASH Histology: Cellular Ballooning.
ANN HEPATOL. 2017; 16(2): 182-184. [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 [OPEN ACCESS]
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Mueller, S; Nahon, P; Rausch, V; Peccerella, T; Silva, I; Yagmur, E; Straub, BK; Lackner, C; Seitz, HK; Rufat, P; Sutton, A; Bantel, H; Longerich, T Caspase-cleaved keratin-18 fragments increase during alcohol withdrawal and predict liver-related death in patients with alcoholic liver disease.
Hepatology. 2017; 66(1):96-107
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Schweiger, M; Romauch, M; Schreiber, R; Grabner, GF; Hütter, S; Kotzbeck, P; Benedikt, P; Eichmann, TO; Yamada, S; Knittelfelder, O; Diwoky, C; Doler, C; Mayer, N; De Cecco, W; Breinbauer, R; Zimmermann, R; Zechner, R Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Nat Commun. 2017; 8(5):14859-14859 [OPEN ACCESS]
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2016

Hartmann, P; Seebauer, CT; Mazagova, M; Horvath, A; Wang, L; Llorente, C; Varki, NM; Brandl, K; Ho, SB; Schnabl, B Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity.
Am J Physiol Gastrointest Liver Physiol. 2016; 310(5):G310-G322 [OPEN ACCESS]
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Munteanu, M; Tiniakos, D; Anstee, Q; Charlotte, F; Marchesini, G; Bugianesi, E; Trauner, M; Romero Gomez, M; Oliveira, C; Day, C; Dufour, JF; Bellentani, S; Ngo, Y; Traussnig, S; Perazzo, H; Deckmyn, O; Bedossa, P; Ratziu, V; Poynard, T; FLIP Consortium and the FibroFrance Group Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference.
Aliment Pharmacol Ther. 2016; 44(8):877-889 [OPEN ACCESS]
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Nawata, A; Noguchi, H; Mazaki, Y; Kurahashi, T; Izumi, H; Wang, KY; Guo, X; Uramoto, H; Kohno, K; Taniguchi, H; Tanaka, Y; Fujii, J; Sasaguri, Y; Tanimoto, A; Nakayama, T; Yamada, S Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease.
PLoS One. 2016; 11(4):e0152549-e0152549 [OPEN ACCESS]
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Rief, P; Pichler, M; Raggam, R; Hafner, F; Gerger, A; Eller, P; Brodmann, M; Gary, T The AST/ALT (De-Ritis) ratio: A novel marker for critical limb ischemia in peripheral arterial occlusive disease patients.
Medicine (Baltimore). 2016; 95(24):e3843-e3843 [OPEN ACCESS]
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2015

Beilfuss, A; Sowa, JP; Sydor, S; Beste, M; Bechmann, LP; Schlattjan, M; Syn, WK; Wedemeyer, I; Mathé, Z; Jochum, C; Gerken, G; Gieseler, RK; Canbay, A Vitamin D counteracts fibrogenic TGF-β signalling in human hepatic stellate cells both receptor-dependently and independently.
Gut. 2015; 64(5):791-799
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Burt, AD; Lackner, C; Tiniakos, DG Diagnosis and Assessment of NAFLD: Definitions and Histopathological Classification.
Semin Liver Dis. 2015; 35(3):207-220 [OPEN ACCESS]
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Jahnel, J; Zöhrer, E; Alisi, A; Ferrari, F; Ceccarelli, S; De Vito, R; Scharnagl, H; Stojakovic, T; Fauler, G; Trauner, M; Nobili, V Serum Bile Acid Levels in Children With Nonalcoholic Fatty Liver Disease.
J Pediatr Gastroenterol Nutr. 2015; 61(1):85-90
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Mangge, H; Baumgartner, BG; Zelzer, S; Prüller, F; Schnedl, WJ; Reininghaus, EZ; Haybaeck, J; Lackner, C; Stauber, R; Aigner, E; Weghuber, D Patatin-like phospholipase 3 (rs738409) gene polymorphism is associated with increased liver enzymes in obese adolescents and metabolic syndrome in all ages.
Aliment Pharmacol Ther. 2015; 42(1):99-105 [OPEN ACCESS]
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Mueller, M; Thorell, A; Claudel, T; Jha, P; Koefeler, H; Lackner, C; Hoesel, B; Fauler, G; Stojakovic, T; Einarsson, C; Marschall, HU; Trauner, M Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity.
J Hepatol. 2015; 62(6):1398-1404 [OPEN ACCESS]
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Nobili, V; Vajro, P; Dezsofi, A; Fischler, B; Hadzic, N; Jahnel, J; Lamireau, T; McKiernan, P; McLin, V; Socha, P; Tizzard, S; Baumann, U Indications and limitations of bariatric intervention in severely obese children and adolescents with and without nonalcoholic steatohepatitis: ESPGHAN Hepatology Committee Position Statement.
J Pediatr Gastroenterol Nutr. 2015; 60(4):550-561
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Stättermayer, AF; Traussnigg, S; Dienes, HP; Aigner, E; Stauber, R; Lackner, K; Hofer, H; Stift, J; Wrba, F; Stadlmayr, A; Datz, C; Strasser, M; Maieron, A; Trauner, M; Ferenci, P Hepatic steatosis in Wilson disease--Role of copper and PNPLA3 mutations.
J Hepatol. 2015; 63(1):156-163
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Wruck, W; Kashofer, K; Rehman, S; Daskalaki, A; Berg, D; Gralka, E; Jozefczuk, J; Drews, K; Pandey, V; Regenbrecht, C; Wierling, C; Turano, P; Korf, U; Zatloukal, K; Lehrach, H; Westerhoff, HV; Adjaye, J Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes.
Sci Data. 2015; 2(S 01):150068-150068 [OPEN ACCESS]
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2014

Bastati, N; Feier, D; Wibmer, A; Traussnigg, S; Balassy, C; Tamandl, D; Einspieler, H; Wrba, F; Trauner, M; Herold, C; Ba-Ssalamah, A Noninvasive differentiation of simple steatosis and steatohepatitis by using gadoxetic acid-enhanced MR imaging in patients with nonalcoholic fatty liver disease: a proof-of-concept study.
Radiology. 2014; 271(3): 739-747. [OPEN ACCESS]
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Bedossa, P; FLIP Pathology Consortium Utility and appropriateness of the fatty liver inhibition of progression (FLIP) algorithm and steatosis, activity, and fibrosis (SAF) score in the evaluation of biopsies of nonalcoholic fatty liver disease.
Hepatology. 2014; 60(2):565-575
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Bettermann, K; Hohensee, T; Haybaeck, J Steatosis and steatohepatitis: complex disorders.
Int J Mol Sci. 2014; 15(6):9924-9944 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Trauner, M Role of metabolic lipases and lipolytic metabolites in the pathogenesis of NAFLD.
Trends Endocrinol Metab. 2014; 25(11):576-585
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Jha, P; Claudel, T; Baghdasaryan, A; Mueller, M; Halilbasic, E; Das, SK; Lass, A; Zimmermann, R; Zechner, R; Hoefler, G; Trauner, M Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia.
Hepatology. 2014; 59(3):858-869 [OPEN ACCESS]
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Jha, P; Knopf, A; Koefeler, H; Mueller, M; Lackner, C; Hoefler, G; Claudel, T; Trauner, M; Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH).
BBA-MOL BASIS DIS. 2014; 1842(7): 959-970. [OPEN ACCESS]
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Kessler, SM; Simon, Y; Gemperlein, K; Gianmoena, K; Cadenas, C; Zimmer, V; Pokorny, J; Barghash, A; Helms, V; van Rooijen, N; Bohle, RM; Lammert, F; Hengstler, JG; Mueller, R; Haybaeck, J; Kiemer, AK Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma.
Int J Mol Sci. 2014; 15(4):5762-5773 [OPEN ACCESS]
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Pandey, V; Sultan, M; Kashofer, K; Ralser, M; Amstislavskiy, V; Starmann, J; Osprian, I; Grimm, C; Hache, H; Yaspo, ML; Sültmann, H; Trauner, M; Denk, H; Zatloukal, K; Lehrach, H; Wierling, C Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains.
PLoS One. 2014; 9(10):e111006-e111006 [OPEN ACCESS]
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Sowa, JP; Atmaca, Ö; Kahraman, A; Schlattjan, M; Lindner, M; Sydor, S; Scherbaum, N; Lackner, K; Gerken, G; Heider, D; Arteel, GE; Erim, Y; Canbay, A Non-invasive separation of alcoholic and non-alcoholic liver disease with predictive modeling.
PLoS One. 2014; 9(7):e101444-e101444 [OPEN ACCESS]
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Stättermayer, AF; Rutter, K; Beinhardt, S; Wrba, F; Scherzer, TM; Strasser, M; Hofer, H; Steindl-Munda, P; Trauner, M; Ferenci, P Role of FDFT1 polymorphism for fibrosis progression in patients with chronic hepatitis C.
Liver Int. 2014; 34(3):388-395
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Wree, A; Schlattjan, M; Bechmann, LP; Claudel, T; Sowa, JP; Stojakovic, T; Scharnagl, H; Köfeler, H; Baba, HA; Gerken, G; Feldstein, AE; Trauner, M; Canbay, A Adipocyte cell size, free fatty acids and apolipoproteins are associated with non-alcoholic liver injury progression in severely obese patients.
Metabolism. 2014; 63(12):1542-1552
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2012

Bechmann, LP; Hannivoort, RA; Gerken, G; Hotamisligil, GS; Trauner, M; Canbay, A The interaction of hepatic lipid and glucose metabolism in liver diseases.
J Hepatol. 2012; 56(4):952-964 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Kumari, P; Haemmerle, G; Pollheimer, MJ; Stojakovic, T; Scharnagl, H; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Trauner, M Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Hepatology. 2012; 56(1):270-280 [OPEN ACCESS]
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Heuer, M; Kaiser, GM; Kahraman, A; Banysch, M; Saner, FH; Mathé, Z; Gerken, G; Paul, A; Canbay, A; Treckmann, JW Liver transplantation in nonalcoholic steatohepatitis is associated with high mortality and post-transplant complications: a single-center experience.
Digestion. 2012; 86(2):107-113
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Jozefczuk, J; Kashofer, K; Ummanni, R; Henjes, F; Rehman, S; Geenen, S; Wruck, W; Regenbrecht, C; Daskalaki, A; Wierling, C; Turano, P; Bertini, I; Korf, U; Zatloukal, K; Westerhoff, HV; Lehrach, H; Adjaye, J A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells.
Front Physiol. 2012; 3(12):339-339 [OPEN ACCESS]
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2011

Lackner, C Hepatocellular ballooning in nonalcoholic steatohepatitis: the pathologist's perspective.
Expert Rev Gastroenterol Hepatol. 2011; 5(2):223-231
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Tannapfel, A; Denk, H; Dienes, HP; Langner, C; Schirmacher, P; Trauner, M; Flott-Rahmel, B Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease.
Virchows Arch. 2011; 458(5): 511-523. [OPEN ACCESS]
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2010

Tannapfel, A; Denk, H; Dienes, HP; Langner, C; Schirmacher, P; Trauner, M; Flott-Rahmel, B Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease. Grade 2 consensus-based guidelines.
Pathologe. 2010; 31(3): 225-237.
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Trauner, M; Claudel, T; Fickert, P; Moustafa, T; Wagner, M Bile acids as regulators of hepatic lipid and glucose metabolism.
Dig Dis. 2010; 28(1):220-224
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