Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: MYELOPEROXIDASE, . Treffer: 145

2023

Arnold, S; Mahrhold, J; Kerstein-Staehle, A; Riemekasten, G; Csernok, E; Hellmich, B; Venhoff, N; Thiel, J; Affeldt, K; Jahnke, A; Lamprecht, P Spectrum of ANCA-specificities in eosinophilic granulomatosis with polyangiitis. A retrospective multicentre study.
Clin Exp Rheumatol. 2023; 41(4):936-942 Doi: 10.55563/clinexprheumatol/299yme
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Wang, YH; Hammer, A; Hoefler, G; Malle, E; Hawkins, CL; Chuang, CY; Davies, MJ Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity
ANTIOXIDANTS-BASEL. 2023; 12(2): 420 Doi: 10.3390/antiox12020420 [OPEN ACCESS]
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2022

Arnhold, J; Malle, E Halogenation Activity of Mammalian Heme Peroxidases.
Antioxidants (Basel). 2022; 11(5): Doi: 10.3390/antiox11050890 [OPEN ACCESS]
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Baranyi, A; Enko, D; Meinitzer, A; Von Lewinski, D; Rothenhäusler, HB; Harpf, L; Traninger, H; Obermayer-Pietsch, B; Harb, BM; Schweinzer, M; Platzer, M; Zelzer, S Myeloperoxidase as a Potential Biomarker of Acute-Myocardial-Infarction-Induced Depression and Suppression of the Innate Immune System.
Antioxidants (Basel). 2022; 11(11): Doi: 10.3390/antiox11112083 [OPEN ACCESS]
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Fuchs, CD; Radun, R; Dixon, ED; Mlitz, V; Timelthaler, G; Halilbasic, E; Herac, M; Jonker, JW; Ronda, OAHO; Tardelli, M; Haemmerle, G; Zimmermann, R; Scharnagl, H; Stojakovic, T; Verkade, HJ; Trauner, M Hepatocyte-specific deletion of adipose triglyceride lipase (adipose triglyceride lipase/patatin-like phospholipase domain containing 2) ameliorates dietary induced steatohepatitis in mice.
Hepatology. 2022; 75(1):125-139 Doi: 10.1002/hep.32112
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Holzwirth, E; Fischer-Schaepmann, T; Obradovic, D; von, Lucadou, M; Schwedhelm, E; Daum, G; Hindricks, G; Marsche, G; Trieb, M; Thiele, H; Kornej, J; Büttner, P Anti-inflammatory HDL effects are impaired in atrial fibrillation.
Heart Vessels. 2022; 37(1):161-171 Doi: 10.1007/s00380-021-01908-w [OPEN ACCESS]
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Jakubauskiene, L; Jakubauskas, M; Razanskiene, G; Leber, B; Weber, J; Rohrhofer, L; Ramasauskaite, D; Strupas, K; Stiegler, P; Schemmer, P Relaxin and Erythropoietin Significantly Reduce Uterine Tissue Damage during Experimental Ischemia-Reperfusion Injury.
INT J MOL SCI. 2022; 23(13): Doi: 10.3390/ijms23137120 [OPEN ACCESS]
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Koyani, CN; Scheruebel, S; Jin, G; Kolesnik, E; Zorn-Pauly, K; Mächler, H; Hoefler, G; von, Lewinski, D; Heinzel, FR; Pelzmann, B; Malle, E Hypochlorite-Modified LDL Induces Arrhythmia and Contractile Dysfunction in Cardiomyocytes.
Antioxidants (Basel). 2021; 11(1): Doi: 10.3390/antiox11010025 [OPEN ACCESS]
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Marsche, G; Stadler, JT; Kargl, J; Holzer, M Understanding Myeloperoxidase-Induced Damage to HDL Structure and Function in the Vessel Wall: Implications for HDL-Based Therapies.
Antioxidants (Basel). 2022; 11(3): Doi: 10.3390/antiox11030556 [OPEN ACCESS]
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Prader, J; Rumpler, M; Kamolz, LP; Hajnsek, M Myeloperoxidase-based in-vitro test strip sensor for early detection of wound infections at the patients bedside
SENSOR ACTUAT B-CHEM. 2022; 372: 132628 Doi: 10.1016/j.snb.2022.132628
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Reynolds, WF; Malle, E; Maki, RA Thiocyanate Reduces Motor Impairment in the hMPO-A53T PD Mouse Model While Reducing MPO-Oxidation of Alpha Synuclein in Enlarged LYVE1/AQP4 Positive Periventricular Glymphatic Vessels
ANTIOXIDANTS-BASEL. 2022; 11(12): 2342 Doi: 10.3390/antiox11122342 [OPEN ACCESS]
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Valadez-Cosmes, P; Raftopoulou, S; Mihalic, ZN; Marsche, G; Kargl, J Myeloperoxidase: Growing importance in cancer pathogenesis and potential drug target.
Pharmacol Ther. 2022; 236:108052 Doi: 10.1016/j.pharmthera.2021.108052
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Xu, S; Chuang, CY; Malle, E; Gamon, LF; Hawkins, CL; Davies, MJ Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage.
Free Radic Biol Med. 2022; 188:162-174 Doi: 10.1016/j.freeradbiomed.2022.06.222
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2021

Hall, L; Guo, C; Tandy, S; Broadhouse, K; Dona, AC; Malle, E; Bartels, ED; Christoffersen, C; Grieve, SM; Figtree, G; Hawkins, CL; Davies, MJ Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats.
Sci Rep. 2021; 11(1):12712 Doi: 10.1038/s41598-021-92142-x [OPEN ACCESS]
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Rosenkranz, AR; Tesar, V Lupus nephritis and ANCA-associated vasculitis: towards precision medicine?
Nephrol Dial Transplant. 2021; 36(Supplement_2): 37-43. Doi: 10.1093/ndt/gfab166 [OPEN ACCESS]
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Sharma, N; Nagaraj, C; Nagy, BM; Marsh, LM; Bordag, N; Zabini, D; Wygrecka, M; Klepetko, W; Gschwandtner, E; Genové, G; Heinemann, A; Weir, EK; Kwapiszewska, G; Olschewski, H; Olschewski, A RGS5 Determines Neutrophil Migration in the Acute Inflammatory Phase of Bleomycin-Induced Lung Injury.
Int J Mol Sci. 2021; 22(17): Doi: 10.3390/ijms22179342 [OPEN ACCESS]
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Sredoja, Tisma, V; Bulimbasic, S; Galesic, Ljubanovic, D; Galesic, K; Morovic-Vergles, J; Mitrovic, J; Uchida, K; Tatzber, F; Zarkovic, N; Jaganjac, M The Onset of Systemic Oxidative Stress Associated with the Accumulation of Lipid Peroxidation Product Acrolein in the Skin of Patients with Small-Vessel Vasculitis.
Molecules. 2021; 26(8): Doi: 10.3390/molecules26082344 [OPEN ACCESS]
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Thai, T; Zhong, F; Dang, L; Chan, E; Ku, J; Malle, E; Geczy, CL; Keaney, JF; Thomas, SR Endothelial-transcytosed myeloperoxidase activates endothelial nitric oxide synthase via a phospholipase C-dependent calcium signaling pathway.
FREE RADICAL BIO MED. 2021; 166(2): 255-264. Doi: 10.1016/j.freeradbiomed.2020.12.448
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Zitkute, V; Kvietkauskas, M; Maskoliunaite, V; Leber, B; Ramasauskaite, D; Strupas, K; Stiegler, P; Schemmer, P Melatonin and Glycine Reduce Uterus Ischemia/Reperfusion Injury in a Rat Model of Warm Ischemia.
Int J Mol Sci. 2021; 22(16): Doi: 10.3390/ijms22168373 [OPEN ACCESS]
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2020

Goeritzer, M; Bernhart, E; Plastira, I; Reicher, H; Leopold, C; Eichmann, TO; Rechberger, G; Madreiter-Sokolowski, CT; Prasch, J; Eller, P; Graier, WF; Kratky, D; Malle, E; Sattler, W Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro.
Int J Mol Sci. 2020; 21(3): Doi: 10.3390/ijms21031143 [OPEN ACCESS]
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Prasch, J; Bernhart, E; Reicher, H; Kollroser, M; Rechberger, GN; Koyani, CN; Trummer, C; Rech, L; Rainer, PP; Hammer, A; Malle, E; Sattler, W Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21239235 [OPEN ACCESS]
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Zitkute, V; Kvietkauskas, M; Maskoliunaite, V; Leber, B; Ramasauskaite, D; Strupas, K; Stiegler, P; Schemmer, P Custodiol-N Is Superior to Custodiol® Solution in Experimental Rat Uterus Preservation.
Int J Mol Sci. 2020; 21(21): Doi: 10.3390/ijms21218015 [OPEN ACCESS]
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2019

Kröpfl, JM; Tschakert, G; Stelzer, I; Pekovits, K; Zelzer, S; Dohr, G; Holasek, S; Stojakovic, T; Scharnagl, H; Spengler, CM; Hofmann, P Acute Exercise-Induced Circulating Haematopoietic Stem and Progenitor Cells in Cardiac Patients - A Case Series.
Heart Lung Circ. 2019; 28(4):e54-e58-e54-e58 Doi: 10.1016/j.hlc.2018.05.095
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Maki, RA; Holzer, M; Motamedchaboki, K; Malle, E; Masliah, E; Marsche, G; Reynolds, WF Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.
Free Radic Biol Med. 2019; 141:115-140 Doi: 10.1016/j.freeradbiomed.2019.05.033 [OPEN ACCESS]
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Mauler, M; Herr, N; Schoenichen, C; Witsch, T; Marchini, T; Härdtner, C; Koentges, C; Kienle, K; Ollivier, V; Schell, M; Dorner, L; Wippel, C; Stallmann, D; Normann, C; Bugger, H; Walther, P; Wolf, D; Ahrens, I; Lämmermann, T; Ho-Tin-Noé, B; Ley, K; Bode, C; Hilgendorf, I; Duerschmied, D Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation.
Circulation. 2019; 139(7):918-931 Doi: 10.1161/CIRCULATIONAHA.118.033942 [OPEN ACCESS]
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Nybo, T; Dieterich, S; Gamon, LF; Chuang, CY; Hammer, A; Hoefler, G; Malle, E; Rogowska-Wrzesinska, A; Davies, MJ Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase.
Redox Biol. 2019; 20:496-513 Doi: 10.1016/j.redox.2018.10.022 [OPEN ACCESS]
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Vanichkitrungruang, S; Chuang, CY; Hawkins, CL; Hammer, A; Hoefler, G; Malle, E; Davies, MJ Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function.
Free Radic Biol Med. 2019; 136(Suppl 1): 118-134. Doi: 10.1016/j.freeradbiomed.2019.04.003
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2018

Bernhart, E; Kogelnik, N; Prasch, J; Gottschalk, B; Goeritzer, M; Depaoli, MR; Reicher, H; Nusshold, C; Plastira, I; Hammer, A; Fauler, G; Malli, R; Graier, WF; Malle, E; Sattler, W 2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.
Redox Biol. 2018; 15:441-451 Doi: 10.1016/j.redox.2018.01.003 [OPEN ACCESS]
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Pussinen, PJ; Malle, E; Sattler, W Importance of maintaining good oral health in cardiometabolic disorders.
Int J Cardiol. 2018; 271(10):291-292 Doi: 10.1016/j.ijcard.2018.07.014 [OPEN ACCESS]
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Zelzer, S; Tatzber, F; Herrmann, M; Wonisch, W; Rinnerhofer, S; Kundi, M; Obermayer-Pietsch, B; Niedrist, T; Cvirn, G; Wultsch, G; Mangge, H Work Intensity, Low-Grade Inflammation, and Oxidative Status: A Comparison between Office and Slaughterhouse Workers.
Oxid Med Cell Longev. 2018; 2018(7):2737563-2737563 Doi: 10.1155/2018/2737563 [OPEN ACCESS]
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Zhang, L; Huang, Z; Shi, X; Hu, S; Litscher, D; Wang, L; Litscher, G Protective Effect of Electroacupuncture at Zusanli on Myocardial Injury in Septic Rats.
Evid Based Complement Alternat Med. 2018; 2018(1):6509650-6509650 Doi: 10.1155/2018/6509650 [OPEN ACCESS]
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2017

Alegría-Landa, V; Rodríguez-Pinilla, SM; Santos-Briz, A; Rodríguez-Peralto, JL; Alegre, V; Cerroni, L; Kutzner, H; Requena, L Clinicopathologic, Immunohistochemical, and Molecular Features of Histiocytoid Sweet Syndrome.
JAMA Dermatol. 2017; 153(7):651-659 Doi: 10.1001/jamadermatol.2016.6092 [OPEN ACCESS]
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Li, B; Lee, C; Martin, Z; Li, X; Koike, Y; Hock, A; Zani-Ruttenstock, E; Zani, A; Pierro, A Intestinal epithelial injury induced by maternal separation is protected by hydrogen sulfide.
J Pediatr Surg. 2017; 52(1): 40-44. Doi: 10.1016/j.jpedsurg.2016.10.013
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Phuah, CL; Dave, T; Malik, R; Raffeld, MR; Ayres, AM; Goldstein, JN; Viswanathan, A; Greenberg, SM; Jagiella, JM; Hansen, BM; Norrving, B; Jimenez-Conde, J; Roquer, J; Pichler, A; Enzinger, C; Montaner, J; Fernandez-Cadenas, I; Lindgren, A; Slowik, A; Schmidt, R; Biffi, A; Rost, N; Langefeld, CD; Markus, HS; Mitchell, BD; Worrall, BB; Kittner, SJ; Woo, D; Dichgans, M; Rosand, J; Anderson, CD; METASTROKE; NINDS-SiGN Consortium; International Stroke Genetics Consortium Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke.
Brain. 2017; 140(10):2663-2672 Doi: 10.1093/brain/awx220 [OPEN ACCESS]
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Zelzer, S; Enko, D; Pilz, S; Tomaschitz, A; März, W; Meinitzer, A Myeloperoxidase, asymmetric dimethyl-arginine and the renin-angiotensin-aldosterone-system in cardiovascular risk patients: Cross-sectional findings from the Ludwigshafen Risk and Cardiovascular Health (LURIC) study.
Clin Biochem. 2017; 50(13-14):739-745 Doi: 10.1016/j.clinbiochem.2017.03.013
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2016

Alfakry, H; Malle, E; Koyani, CN; Pussinen, PJ; Sorsa, T Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease.
Innate Immun. 2016; 22(1):85-99 Doi: 10.1177/1753425915617521 [OPEN ACCESS]
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Jandl, K; Stacher, E; Bálint, Z; Sturm, EM; Maric, J; Peinhaupt, M; Luschnig, P; Aringer, I; Fauland, A; Konya, V; Dahlen, SE; Wheelock, CE; Kratky, D; Olschewski, A; Marsche, G; Schuligoi, R; Heinemann, A Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung.
J Allergy Clin Immunol. 2016; 137(3):833-843 Doi: 10.1016/j.jaci.2015.11.012 [OPEN ACCESS]
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Mangge, H Beyond Cholesterol - New Cardiovascular Biomarkers.
Nestle Nutr Inst Workshop Ser. 2016; 84: 81-88. Doi: 10.1159/000436990
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Nusshold, C; Üllen, A; Kogelnik, N; Bernhart, E; Reicher, H; Plastira, I; Glasnov, T; Zangger, K; Rechberger, G; Kollroser, M; Fauler, G; Wolinski, H; Weksler, BB; Romero, IA; Kohlwein, SD; Couraud, PO; Malle, E; Sattler, W Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
Free Radic Biol Med. 2016; 90: 59-74. Doi: 10.1016/j.freeradbiomed.2015.11.010 [OPEN ACCESS]
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Zádori, ZS; Tóth, VE; Fehér, Á; Al-Khrasani, M; Puskár, Z; Kozsurek, M; Timár, J; Tábi, T; Helyes, Z; Hein, L; Holzer, P; Gyires, K Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium-Induced Acute Intestinal Inflammation in Mice.
J Pharmacol Exp Ther. 2016; 358(3):483-491 Doi: 10.1124/jpet.116.235101 [OPEN ACCESS]
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2015

Hajnsek, M; Schiffer, D; Harrich, D; Koller, D; Verient, V; van der Palen, J; Heinzle, A; Binder, B; Sigl, E; Sinner, F; Guebitz, GM An electrochemical sensor for fast detection of wound infection based on myeloperoxidase activity
SENSOR ACTUAT B-CHEM. 2015; 209: 265-274. Doi: 10.1016/j.snb.2014.11.125
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Koyani, CN; Flemmig, J; Malle, E; Arnhold, J Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme.
Arch Biochem Biophys. 2015; 571(7):1-9 Doi: 10.1016/j.abb.2015.02.028 [OPEN ACCESS]
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Stančić, A; Jandl, K; Hasenöhrl, C; Reichmann, F; Marsche, G; Schuligoi, R; Heinemann, A; Storr, M; Schicho, R The GPR55 antagonist CID16020046 protects against intestinal inflammation.
Neurogastroenterol Motil. 2015; 27(10):1432-1445 Doi: 10.1111/nmo.12639 [OPEN ACCESS]
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Tomazic, PV; Birner-Gruenberger, R; Leitner, A; Darnhofer, B; Spoerk, S; Lang-Loidolt, D Apolipoproteins have a potential role in nasal mucus of allergic rhinitis patients: a proteomic study.
Laryngoscope. 2015; 125(3):E91-E96 Doi: 10.1002/lary.25003
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Üllen, A; Nusshold, C; Glasnov, T; Saf, R; Cantillo, D; Eibinger, G; Reicher, H; Fauler, G; Bernhart, E; Hallstrom, S; Kogelnik, N; Zangger, K; Oliver Kappe, C; Malle, E; Sattler, W Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin.
Biochem Pharmacol. 2015; 93(4):470-481 Doi: 10.1016/j.bcp.2014.12.017 [OPEN ACCESS]
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2014

Bast, A; Krause, K; Schmidt, IH; Pudla, M; Brakopp, S; Hopf, V; Breitbach, K; Steinmetz, I Caspase-1-dependent and -independent cell death pathways in Burkholderia pseudomallei infection of macrophages.
PLoS Pathog. 2014; 10(3): e1003986-e1003986. Doi: 10.1371/journal.ppat.1003986 [OPEN ACCESS]
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Delporte, C; Boudjeltia, KZ; Noyon, C; Furtmüller, PG; Nuyens, V; Slomianny, MC; Madhoun, P; Desmet, JM; Raynal, P; Dufour, D; Koyani, CN; Reyé, F; Rousseau, A; Vanhaeverbeek, M; Ducobu, J; Michalski, JC; Nève, J; Vanhamme, L; Obinger, C; Malle, E; Van Antwerpen, P Impact of myeloperoxidase-LDL interactions on enzyme activity and subsequent posttranslational oxidative modifications of apoB-100.
J Lipid Res. 2014; 55(4):747-757 Doi: 10.1194/jlr.M047449 [OPEN ACCESS]
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Hassan, AM; Jain, P; Reichmann, F; Mayerhofer, R; Farzi, A; Schuligoi, R; Holzer, P Repeated predictable stress causes resilience against colitis-induced behavioral changes in mice.
Front Behav Neurosci. 2014; 8(6):386-386 Doi: 10.3389/fnbeh.2014.00386 [OPEN ACCESS]
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Prietl, B; Meindl, C; Roblegg, E; Pieber, TR; Lanzer, G; Fröhlich, E Nano-sized and micro-sized polystyrene particles affect phagocyte function.
Cell Biol Toxicol. 2014; 30(1):1-16 Doi: 10.1007/s10565-013-9265-y [OPEN ACCESS]
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Scharnagl, H; Kleber, ME; Genser, B; Kickmaier, S; Renner, W; Weihrauch, G; Grammer, T; Rossmann, C; Winkelmann, BR; Boehm, BO; Sattler, W; März, W; Malle, E Association of myeloperoxidase with total and cardiovascular mortality in individuals undergoing coronary angiography--the LURIC study.
Int J Cardiol. 2014; 174(1):96-105 Doi: 10.1016/j.ijcard.2014.03.168 [OPEN ACCESS]
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