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Publikationen

Suchbegriffe: MICE, KNOCKOUT - , . Treffer: 289

2021

Schwarze, UY; Ni, Y; Zhou, Y; Terlecki-Ζaniewicz, L; Schosserer, M; Hackl, M; Grillari, J; Gruber, R Size changes in miR‑21 knockout mice: Geometric morphometrics on teeth, alveolar bone and mandible.
MOL MED REP. 2021; 23(4): 285 Doi: 10.3892/mmr.2021.11924 [OPEN ACCESS]
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Tardelli, M; Bruschi, FV; Fuchs, CD; Claudel, T; Auer, N; Kunczer, V; Ronda, OAHO; Verkade, HJ; Stojakovic, T; Scharnagl, H; Trauner, M Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice.
Int J Mol Sci. 2021; 22(4): Doi: 10.3390/ijms22042126 [OPEN ACCESS]
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2020

Doerflinger, M; Deng, Y; Whitney, P; Salvamoser, R; Engel, S; Kueh, AJ; Tai, L; Bachem, A; Gressier, E; Geoghegan, ND; Wilcox, S; Rogers, KL; Garnham, AL; Dengler, MA; Bader, SM; Ebert, G; Pearson, JS; De Nardo, D; Wang, N; Yang, C; Pereira, M; Bryant, CE; Strugnell, RA; Vince, JE; Pellegrini, M; Strasser, A; Bedoui, S; Herold, MJ Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection.
Immunity. 2020; 53(3):533-547 Doi: 10.1016/j.immuni.2020.07.004 [OPEN ACCESS]
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Jain, P; Materazzi, S; De Logu, F; Rossi Degl'Innocenti, D; Fusi, C; Li Puma, S; Marone, IM; Coppi, E; Holzer, P; Geppetti, P; Nassini, R Transient receptor potential ankyrin 1 contributes to somatic pain hypersensitivity in experimental colitis.
Sci Rep. 2020; 10(1):8632-8632 Doi: 10.1038/s41598-020-65618-5 [OPEN ACCESS]
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Jha, S; Taschler, U; Domenig, O; Poglitsch, M; Bourgeois, B; Pollheimer, M; Pusch, LM; Malovan, G; Frank, S; Madl, T; Gruber, K; Zimmermann, R; Macheroux, P Dipeptidyl peptidase 3 modulates the renin-angiotensin system in mice.
J Biol Chem. 2020; 295(40):13711-13723 Doi: 10.1074/jbc.RA120.014183 [OPEN ACCESS]
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Moschovaki Filippidou, F; Kirsch, AH; Thelen, M; Kétszeri, M; Artinger, K; Aringer, I; Schabhüttl, C; Mooslechner, AA; Frauscher, B; Pollheimer, M; Niedrist, T; Meinitzer, A; Drucker, DJ; Pieber, TR; Eller, P; Rosenkranz, AR; Heinemann, A; Eller, K Glucagon-Like Peptide-1 Receptor Agonism Improves Nephrotoxic Serum Nephritis by Inhibiting T-Cell Proliferation.
Am J Pathol. 2020; 190(2):400-411 Doi: 10.1016/j.ajpath.2019.10.008 [OPEN ACCESS]
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Sladky, VC; Knapp, K; Soratroi, C; Heppke, J; Eichin, F; Rocamora-Reverte, L; Szabo, TG; Bongiovanni, L; Westendorp, B; Moreno, E; van Liere, EA; Bakker, B; Spierings, DCJ; Wardenaar, R; Pereyra, D; Starlinger, P; Schultze, S; Trauner, M; Stojakovic, T; Scharnagl, H; Fava, LL; Foijer, F; de Bruin, A; Villunger, A E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration.
Dev Cell. 2020; 52(3):335-349 Doi: 10.1016/j.devcel.2019.12.016
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Wagner, C; Hois, V; Pajed, L; Pusch, LM; Wolinski, H; Trauner, M; Zimmermann, R; Taschler, U; Lass, A Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 1865(8): 158730-158730. Doi: 10.1016/j.bbalip.2020.158730 [OPEN ACCESS]
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2019

Grill, M; Hasenoehrl, C; Kienzl, M; Kargl, J; Schicho, R Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation.
Histochem Cell Biol. 2019; 151(1):5-20 Doi: 10.1007/s00418-018-1719-0 [OPEN ACCESS]
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Hofer, DC; Zirkovits, G; Pelzmann, HJ; Huber, K; Pessentheiner, AR; Xia, W; Uno, K; Miyazaki, T; Kon, K; Tsuneki, H; Pendl, T; Al Zoughbi, W; Madreiter-Sokolowski, CT; Trausinger, G; Abdellatif, M; Schoiswohl, G; Schreiber, R; Eisenberg, T; Magnes, C; Sedej, S; Eckhardt, M; Sasahara, M; Sasaoka, T; Nitta, A; Hoefler, G; Graier, WF; Kratky, D; Auwerx, J; Bogner-Strauss, JG N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health.
FASEB J. 2019; 33(12):13808-13824 Doi: 10.1096/fj.201801323R [OPEN ACCESS]
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Müller, N; Fischer, JC; Yabal, M; Haas, T; Poeck, H; Jost, PJ XIAP deficiency in hematopoietic recipient cells drives donor T-cell activation and GvHD in mice.
Eur J Immunol. 2019; 49(3):504-507 Doi: 10.1002/eji.201847818
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Willecke, F; Rupprecht, B; Gissler, MC; Pfeiffer, K; Anto-Michel, N; Stachon, P; Wolf, D; Hilgendorf, I; Hoppe, N; Bode, C; Zirlik, A Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation.
J Vasc Res. 2019; 56(6):308-319 Doi: 10.1159/000501615
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2018

Biasin, V; Wygrecka, M; Bärnthaler, T; Jandl, K; Jain, PP; Bálint, Z; Kovacs, G; Leitinger, G; Kolb-Lenz, D; Kornmueller, K; Peters, F; Sinn, K; Klepetko, W; Heinemann, A; Olschewski, A; Becker-Pauly, C; Kwapiszewska, G Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation.
Thromb Haemost. 2018; 118(10):1790-1802 Doi: 10.1055/s-0038-1670657
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Early, JO; Menon, D; Wyse, CA; Cervantes-Silva, MP; Zaslona, Z; Carroll, RG; Palsson-McDermott, EM; Angiari, S; Ryan, DG; Corcoran, SE; Timmons, G; Geiger, SS; Fitzpatrick, DJ; O'Connell, D; Xavier, RJ; Hokamp, K; O'Neill, LAJ; Curtis, AM Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.
Proc Natl Acad Sci U S A. 2018; 115(36): E8460-E8468. Doi: 10.1073/pnas.1800431115 [OPEN ACCESS]
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Fuchs, CD; Paumgartner, G; Mlitz, V; Kunczer, V; Halilbasic, E; Leditznig, N; Wahlström, A; Ståhlman, M; Thüringer, A; Kashofer, K; Stojakovic, T; Marschall, HU; Trauner, M Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2^-/- mice by modulating composition, signalling and excretion of faecal bile acids.
Gut. 2018; 67(9):1683-1691 Doi: 10.1136/gutjnl-2017-314553 [OPEN ACCESS]
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Hasenoehrl, C; Feuersinger, D; Sturm, EM; Bärnthaler, T; Heitzer, E; Graf, R; Grill, M; Pichler, M; Beck, S; Butcher, L; Thomas, D; Ferreirós, N; Schuligoi, R; Schweiger, C; Haybaeck, J; Schicho, R G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.
Int J Cancer. 2018; 142(1):121-132 Doi: 10.1002/ijc.31030 [OPEN ACCESS]
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Merz, J; Albrecht, P; von Garlen, S; Ahmed, I; Dimanski, D; Wolf, D; Hilgendorf, I; Härdtner, C; Grotius, K; Willecke, F; Heidt, T; Bugger, H; Hoppe, N; Kintscher, U; von Zur Mühlen, C; Idzko, M; Bode, C; Zirlik, A; Stachon, P Purinergic receptor Y₂ (P2Y₂)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome.
Basic Res Cardiol. 2018; 113(6):45-45 Doi: 10.1007/s00395-018-0702-1
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Teufelberger, AR; Nordengrün, M; Braun, H; Maes, T; De Grove, K; Holtappels, G; O'Brien, C; Provoost, S; Hammad, H; Gonçalves, A; Beyaert, R; Declercq, W; Vandenabeele, P; Krysko, DV; Bröker, BM; Bachert, C; Krysko, O The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D.
J Allergy Clin Immunol. 2018; 141(2): 549-559. Doi: 10.1016/j.jaci.2017.05.004
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Xia, W; Pessentheiner, AR; Hofer, DC; Amor, M; Schreiber, R; Schoiswohl, G; Eichmann, TO; Walenta, E; Itariu, B; Prager, G; Hackl, H; Stulnig, T; Kratky, D; Rülicke, T; Bogner-Strauss, JG Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance.
Cell Rep. 2018; 23(7):1948-1961 Doi: 10.1016/j.celrep.2018.04.055 [OPEN ACCESS]
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2017

Baker, D; Pryce, G; Visintin, C; Sisay, S; Bondarenko, AI; Vanessa Ho, WS; Jackson, SJ; Williams, TE; Al-Izki, S; Sevastou, I; Okuyama, M; Graier, WF; Stevenson, LA; Tanner, C; Ross, R; Pertwee, RG; Henstridge, CM; Irving, AJ; Schulman, J; Powell, K; Baker, MD; Giovannoni, G; Selwood, DL Big conductance calcium-activated potassium channel openers control spasticity without sedation.
Br J Pharmacol. 2017; 174(16):2662-2681 Doi: 10.1111/bph.13889 [OPEN ACCESS]
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Bast, A; Kubis, H; Holtfreter, B; Ribback, S; Martin, H; Schreiner, HC; Dominik, MJ; Breitbach, K; Dombrowski, F; Kocher, T; Steinmetz, I NADPH Oxidase Contributes to Resistance against Aggregatibacter actinomycetemcomitans-Induced Periodontitis in Mice.
Infect Immun. 2017; 85(2): Doi: 10.1128/IAI.00849-16 [OPEN ACCESS]
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Biasin, V; Wygrecka, M; Marsh, LM; Becker-Pauly, C; Brcic, L; Ghanim, B; Klepetko, W; Olschewski, A; Kwapiszewska, G Meprin β contributes to collagen deposition in lung fibrosis.
Sci Rep. 2017; 7(1):39969-39969 Doi: 10.1038/srep39969 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 Doi: 10.1002/1873-3468.12845 [OPEN ACCESS]
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Hassan, AM; Jain, P; Mayerhofer, R; Fröhlich, EE; Farzi, A; Reichmann, F; Herzog, H; Holzer, P Visceral hyperalgesia caused by peptide YY deletion and Y2 receptor antagonism.
Sci Rep. 2017; 7(6):40968-40968 Doi: 10.1038/srep40968 [OPEN ACCESS]
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Kweider, N; Huppertz, B; Rath, W; Lambertz, J; Caspers, R; ElMoursi, M; Pecks, U; Kadyrov, M; Fragoulis, A; Pufe, T; Wruck, CJ The effects of Nrf2 deletion on placental morphology and exchange capacity in the mouse.
J Matern Fetal Neonatal Med. 2017; 30(17):2068-2073 Doi: 10.1080/14767058.2016.1236251
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Lawlor, KE; Feltham, R; Yabal, M; Conos, SA; Chen, KW; Ziehe, S; Graß, C; Zhan, Y; Nguyen, TA; Hall, C; Vince, AJ; Chatfield, SM; D'Silva, DB; Pang, KC; Schroder, K; Silke, J; Vaux, DL; Jost, PJ; Vince, JE XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.
Cell Rep. 2017; 20(3):668-682 Doi: 10.1016/j.celrep.2017.06.073 [OPEN ACCESS]
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Lunova, M; Schwarz, P; Nuraldeen, R; Levada, K; Kuscuoglu, D; Stützle, M; Vujić Spasić, M; Haybaeck, J; Ruchala, P; Jirsa, M; Deschemin, JC; Vaulont, S; Trautwein, C; Strnad, P Hepcidin knockout mice spontaneously develop chronic pancreatitis owing to cytoplasmic iron overload in acinar cells.
J Pathol. 2017; 241(1):104-114 Doi: 10.1002/path.4822 [OPEN ACCESS]
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Nagaraj, C; Tabeling, C; Nagy, BM; Jain, PP; Marsh, LM; Papp, R; Pienn, M; Witzenrath, M; Ghanim, B; Klepetko, W; Weir, EK; Heschl, S; Kwapiszewska, G; Olschewski, A; Olschewski, H Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.
Eur Respir J. 2017; 50(1): Doi: 10.1183/13993003.01651-2016 [OPEN ACCESS]
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Nelson, ME; Lahiri, S; Chow, JD; Byrne, FL; Hargett, SR; Breen, DS; Olzomer, EM; Wu, LE; Cooney, GJ; Turner, N; James, DE; Slack-Davis, JK; Lackner, C; Caldwell, SH; Hoehn, KL Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.
Nat Commun. 2017; 8(6):14689-14689 Doi: 10.1038/ncomms14689 [OPEN ACCESS]
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Olschewski, A; Veale, EL; Nagy, BM; Nagaraj, C; Kwapiszewska, G; Antigny, F; Lambert, M; Humbert, M; Czirják, G; Enyedi, P; Mathie, A TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.
Eur Respir J. 2017; 50(5): Doi: 10.1183/13993003.00754-2017 [OPEN ACCESS]
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Pessentheiner, AR; Huber, K; Pelzmann, HJ; Prokesch, A; Radner, FPW; Wolinski, H; Lindroos-Christensen, J; Hoefler, G; Rülicke, T; Birner-Gruenberger, R; Bilban, M; Bogner-Strauss, JG APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion.
FASEB J. 2017; 31(9):4088-4103 Doi: 10.1096/fj.201601337R [OPEN ACCESS]
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Schlager, S; Vujic, N; Korbelius, M; Duta-Mare, M; Dorow, J; Leopold, C; Rainer, S; Wegscheider, M; Reicher, H; Ceglarek, U; Sattler, W; Radovic, B; Kratky, D Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages.
Oncotarget. 2017; 8(25):40037-40051 Doi: 10.18632/oncotarget.16673 [OPEN ACCESS]
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Schreiber, R; Diwoky, C; Schoiswohl, G; Feiler, U; Wongsiriroj, N; Abdellatif, M; Kolb, D; Hoeks, J; Kershaw, EE; Sedej, S; Schrauwen, P; Haemmerle, G; Zechner, R Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue.
Cell Metab. 2017; 26(5):753-763 Doi: 10.1016/j.cmet.2017.09.004 [OPEN ACCESS]
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Schrumpf, E; Jiang, X; Zeissig, S; Pollheimer, MJ; Anmarkrud, JA; Tan, C; Exley, MA; Karlsen, TH; Blumberg, RS; Melum, E The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation.
Physiol Rep. 2017; 5(4): Doi: 10.14814/phy2.13117 [OPEN ACCESS]
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Stachon, P; Heidenreich, A; Merz, J; Hilgendorf, I; Wolf, D; Willecke, F; von Garlen, S; Albrecht, P; Härdtner, C; Ehrat, N; Hoppe, N; Reinöhl, J; von Zur Mühlen, C; Bode, C; Idzko, M; Zirlik, A P2X₇ Deficiency Blocks Lesional Inflammasome Activity and Ameliorates Atherosclerosis in Mice.
CIRCULATION. 2017; 135(25): 2524-2533. Doi: 10.1161/CIRCULATIONAHA.117.027400
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Taniguchi, K; Moroishi, T; de Jong, PR; Krawczyk, M; Grebbin, BM; Luo, H; Xu, RH; Golob-Schwarzl, N; Schweiger, C; Wang, K; Di Caro, G; Feng, Y; Fearon, ER; Raz, E; Kenner, L; Farin, HF; Guan, KL; Haybaeck, J; Datz, C; Zhang, K; Karin, M YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
Proc Natl Acad Sci U S A. 2017; 114(7):1643-1648 Doi: 10.1073/pnas.1620290114 [OPEN ACCESS]
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Thangaratnarajah, C; Dinger, K; Vohlen, C; Klaudt, C; Nawabi, J; Lopez Garcia, E; Kwapiszewska, G; Dobner, J; Nüsken, KD; van Koningsbruggen-Rietschel, S; von Hörsten, S; Dötsch, J; Alejandre Alcázar, MA Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction.
Am J Physiol Lung Cell Mol Physiol. 2017; 313(3):L491-L506 Doi: 10.1152/ajplung.00432.2016 [OPEN ACCESS]
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Toib, A; Zhang, C; Borghetti, G; Zhang, X; Wallner, M; Yang, Y; Troupes, CD; Kubo, H; Sharp, TE; Feldsott, E; Berretta, RM; Zalavadia, N; Trappanese, DM; Harper, S; Gross, P; Chen, X; Mohsin, S; Houser, SR Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.
Am J Physiol Heart Circ Physiol. 2017; 313(3):H620-H630 Doi: 10.1152/ajpheart.00167.2017 [OPEN ACCESS]
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Windpassinger, C; Piard, J; Bonnard, C; Alfadhel, M; Lim, S; Bisteau, X; Blouin, S; Ali, NB; Ng, AYJ; Lu, H; Tohari, S; Talib, SZA; van Hul, N; Caldez, MJ; Van Maldergem, L; Yigit, G; Kayserili, H; Youssef, SA; Coppola, V; de Bruin, A; Tessarollo, L; Choi, H; Rupp, V; Roetzer, K; Roschger, P; Klaushofer, K; Altmüller, J; Roy, S; Venkatesh, B; Ganger, R; Grill, F; Ben Chehida, F; Wollnik, B; Altunoglu, U; Al Kaissi, A; Reversade, B; Kaldis, P CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
Am J Hum Genet. 2017; 101(3): 391-403. Doi: 10.1016/j.ajhg.2017.08.003 [OPEN ACCESS]
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Wolf, D; Bukosza, N; Engel, D; Poggi, M; Jehle, F; Anto Michel, N; Chen, YC; Colberg, C; Hoppe, N; Dufner, B; Boon, L; Blankenbach, H; Hilgendorf, I; von Zur Muhlen, C; Reinöhl, J; Sommer, B; Marchini, T; Febbraio, MA; Weber, C; Bode, C; Peter, K; Lutgens, E; Zirlik, A Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).
Thromb Haemost. 2017; 117(2):325-338 Doi: 10.1160/TH16-07-0553
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2016

Alesutan, I; Feger, M; Tuffaha, R; Castor, T; Musculus, K; Buehling, SS; Heine, CL; Kuro-O, M; Pieske, B; Schmidt, K; Tomaschitz, A; Maerz, W; Pilz, S; Meinitzer, A; Voelkl, J; Lang, F Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine.
Cardiovasc Res. 2016; 110(3):408-418 Doi: 10.1093/cvr/cvw062 [OPEN ACCESS]
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Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 Doi: 10.18632/oncotarget.9418 [OPEN ACCESS]
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Bartuzi, P; Billadeau, DD; Favier, R; Rong, S; Dekker, D; Fedoseienko, A; Fieten, H; Wijers, M; Levels, JH; Huijkman, N; Kloosterhuis, N; van der Molen, H; Brufau, G; Groen, AK; Elliott, AM; Kuivenhoven, JA; Plecko, B; Grangl, G; McGaughran, J; Horton, JD; Burstein, E; Hofker, MH; van de Sluis, B CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Nat Commun. 2016; 7(5):10961-10961 Doi: 10.1038/ncomms10961 [OPEN ACCESS]
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Bettermann, K; Mehta, AK; Hofer, EM; Wohlrab, C; Golob-Schwarzl, N; Svendova, V; Schimek, MG; Stumptner, C; Thüringer, A; Speicher, MR; Lackner, C; Zatloukal, K; Denk, H; Haybaeck, J Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis.
Oncotarget. 2016; 7(45):73309-73322 Doi: 10.18632/oncotarget.12325 [OPEN ACCESS]
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Grün, NG; Strohmeier, K; Moreno-Viedma, V; Le Bras, M; Landlinger, C; Zeyda, K; Wanko, B; Leitner, L; Staffler, G; Zeyda, M; Stulnig, TM Peptide-based vaccination against OPN integrin binding sites does not improve cardio-metabolic disease in mice.
Immunol Lett. 2016; 179(11):85-94 Doi: 10.1016/j.imlet.2016.09.006 [OPEN ACCESS]
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Hartmann, P; Seebauer, CT; Mazagova, M; Horvath, A; Wang, L; Llorente, C; Varki, NM; Brandl, K; Ho, SB; Schnabl, B Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity.
Am J Physiol Gastrointest Liver Physiol. 2016; 310(5):G310-G322 Doi: 10.1152/ajpgi.00094.2015 [OPEN ACCESS]
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Jeric, I; Maurer, G; Cavallo, AL; Raguz, J; Desideri, E; Tarkowski, B; Parrini, M; Fischer, I; Zatloukal, K; Baccarini, M A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nat Commun. 2016; 7(12):13781-13781 Doi: 10.1038/ncomms13781 [OPEN ACCESS]
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Koentges, C; Pfeil, K; Meyer-Steenbuck, M; Lother, A; Hoffmann, MM; Odening, KE; Hein, L; Bode, C; Bugger, H Preserved recovery of cardiac function following ischemia-reperfusion in mice lacking SIRT3.
Can J Physiol Pharmacol. 2016; 94(1): 72-80. Doi: 10.1139/cjpp-2015-0152
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Metz, HE; Kargl, J; Busch, SE; Kim, KH; Kurland, BF; Abberbock, SR; Randolph-Habecker, J; Knoblaugh, SE; Kolls, JK; White, MF; Houghton, AM Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.
Proc Natl Acad Sci U S A. 2016; 113(31):8795-8800 Doi: 10.1073/pnas.1601989113 [OPEN ACCESS]
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Nagaraj, C; Tang, B; Nagy, BM; Papp, R; Jain, PP; Marsh, LM; Meredith, AL; Ghanim, B; Klepetko, W; Kwapiszewska, G; Weir, EK; Olschewski, H; Olschewski, A Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension.
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