Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Publikationen
Suchbegriffe: MELANOMA - GENETICS , . Treffer: 86
2019
Saggini, A; Cerroni, L; Casini, B; Baciorri, F; Cota, C
Primary intrafascial desmoplastic melanoma with pseudoglandular differentiation and aberrant cytokeratins expression: An exceptional presentation.
Pathol Res Pract. 2019; 215(12):152668-152668
Doi: 10.1016/j.prp.2019.152668
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2017
Ofner, R; Ritter, C; Heidenreich, B; Kumar, R; Ugurel, S; Schrama, D; Becker, JC
Distribution of TERT promoter mutations in primary and metastatic melanomas in Austrian patients.
J Cancer Res Clin Oncol. 2017; 143(4):613-617
Doi: 10.1007/s00432-016-2322-1
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Ofner, R; Ritter, C; Ugurel, S; Cerroni, L; Stiller, M; Bogenrieder, T; Solca, F; Schrama, D; Becker, JC
Non-reproducible sequence artifacts in FFPE tissue: an experience report.
J Cancer Res Clin Oncol. 2017; 143(7):1199-1207
Doi: 10.1007/s00432-017-2399-1
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Richtig, G; Ehall, B; Richtig, E; Aigelsreiter, A; Gutschner, T; Pichler, M
Function and Clinical Implications of Long Non-Coding RNAs in Melanoma.
Int J Mol Sci. 2017; 18(4):
Doi: 10.3390/ijms18040715
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Richtig, G; Hoeller, C; Kashofer, K; Aigelsreiter, A; Heinemann, A; Kwong, LN; Pichler, M; Richtig, E
Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.
Br J Dermatol. 2017; 177(4):936-944
Doi: 10.1111/bjd.15436
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Richtig, G; Richtig, E; Kashofer, K; Koch, L; Winter, G; Hoefler, G; Pichler, M; Ehall, B; Grübler, MR; Heinemann, A; Aigelsreiter, A
Testing and clinical implications for non-V600 BRAF mutations in metastatic NRASmt melanoma.
Br J Dermatol. 2017; 177(3):860-861
Doi: 10.1111/bjd.15222
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Rinner, B; Gandolfi, G; Meditz, K; Frisch, MT; Wagner, K; Ciarrocchi, A; Torricelli, F; Koivuniemi, R; Niklander, J; Liegl-Atzwanger, B; Lohberger, B; Heitzer, E; Ghaffari-Tabrizi-Wizsy, N; Zweytick, D; Zalaudek, I
MUG-Mel2, a novel highly pigmented and well characterized NRAS mutated human melanoma cell line.
Sci Rep. 2017; 7(1):2098-2098
Doi: 10.1038/s41598-017-02197-y
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Yeh, I; Lang, UE; Durieux, E; Tee, MK; Jorapur, A; Shain, AH; Haddad, V; Pissaloux, D; Chen, X; Cerroni, L; Judson, RL; LeBoit, PE; McCalmont, TH; Bastian, BC; de la Fouchardière, A
Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi.
Nat Commun. 2017; 8(1):644-644
Doi: 10.1038/s41467-017-00758-3
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2016
Busam, KJ; Vilain, RE; Lum, T; Busam, JA; Hollmann, TJ; Saw, RP; Coit, DC; Scolyer, RA; Wiesner, T
Primary and Metastatic Cutaneous Melanomas Express ALK Through Alternative Transcriptional Initiation.
Am J Surg Pathol. 2016; 40(6):786-795
Doi: 10.1097/PAS.0000000000000611
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Gandolfi, G; Longo, C; Moscarella, E; Zalaudek, I; Sancisi, V; Raucci, M; Manzotti, G; Gugnoni, M; Piana, S; Argenziano, G; Ciarrocchi, A
The extent of whole-genome copy number alterations predicts aggressive features in primary melanomas.
Pigment Cell Melanoma Res. 2016; 29(2):163-175
Doi: 10.1111/pcmr.12436
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Garg, K; Maurer, M; Griss, J; Brüggen, MC; Wolf, IH; Wagner, C; Willi, N; Mertz, KD; Wagner, SN
Tumor-associated B cells in cutaneous primary melanoma and improved clinical outcome.
Hum Pathol. 2016; 54(6):157-164
Doi: 10.1016/j.humpath.2016.03.022
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Wiesner, T
Genomic Rearrangements in Unusual and Atypical Melanocytic Neoplasms.
JAMA Dermatol. 2016; 152(3):260-262
Doi: 10.1001/jamadermatol.2015.3501
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Wiesner, T; Kutzner, H; Cerroni, L; Mihm, MC; Busam, KJ; Murali, R
Genomic aberrations in spitzoid melanocytic tumours and their implications for diagnosis, prognosis and therapy.
Pathology. 2016; 48(2):113-131
Doi: 10.1016/j.pathol.2015.12.007
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Woltsche, N; Schwab, C; Deinlein, T; Hofmann-Wellenhof, R; Zalaudek, I
Dermoscopy in the era of dermato-oncology: from bed to bench side and retour.
Expert Rev Anticancer Ther. 2016; 16(5):531-541
Doi: 10.1586/14737140.2016.1168700
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2015
Aoude, LG; Heitzer, E; Johansson, P; Gartside, M; Wadt, K; Pritchard, AL; Palmer, JM; Symmons, J; Gerdes, AM; Montgomery, GW; Martin, NG; Tomlinson, I; Kearsey, S; Hayward, NK
POLE mutations in families predisposed to cutaneous melanoma.
Fam Cancer. 2015; 14(4):621-628
Doi: 10.1007/s10689-015-9826-8
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Jahn, SW; Kashofer, K; Halbwedl, I; Winter, G; El-Shabrawi-Caelen, L; Mentzel, T; Hoefler, G; Liegl-Atzwanger, B
Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis.
Mod Pathol. 2015; 28(7):895-903
Doi: 10.1038/modpathol.2015.39
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Shain, AH; Garrido, M; Botton, T; Talevich, E; Yeh, I; Sanborn, JZ; Chung, J; Wang, NJ; Kakavand, H; Mann, GJ; Thompson, JF; Wiesner, T; Roy, R; Olshen, AB; Gagnon, A; Gray, JW; Huh, N; Hur, JS; Busam, KJ; Scolyer, RA; Cho, RJ; Murali, R; Bastian, BC
Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Nat Genet. 2015; 47(10): 1194-1199.
Doi: 10.1038/ng.3382
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Wiesner, T; Kiuru, M; Scott, SN; Arcila, M; Halpern, AC; Hollmann, T; Berger, MF; Busam, KJ
NF1 Mutations Are Common in Desmoplastic Melanoma.
Am J Surg Pathol. 2015; 39(10): 1357-1362.
Doi: 10.1097/PAS.0000000000000451
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Wiesner, T; Kutzner, H
Morphological and genetic aspects of Spitz tumors].
Pathologe. 2015; 36(1): 37-43.
Doi: 10.1007/s00292-014-1984-1
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Zalaudek, I; Ciarrocchi, A; Piana, S; Argenziano, G; Torricelli, F; Sancisi, V; Gandolfi, G; Longo, C; Moscarella, E; Banzi, C; Nicoli, D
A novel BRAF mutation in association with primary amelanotic melanoma with oral metastases.
J Eur Acad Dermatol Venereol. 2015; 29(2):387-390
Doi: 10.1111/jdv.12358
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2014
Goldinger, SM; Zimmer, L; Schulz, C; Ugurel, S; Hoeller, C; Kaehler, KC; Schadendorf, D; Hassel, JC; Becker, J; Hauschild, A; Dummer, R; Dermatology Cooperative Oncology Group (DeCOG)
Upstream mitogen-activated protein kinase (MAPK) pathway inhibition: MEK inhibitor followed by a BRAF inhibitor in advanced melanoma patients.
Eur J Cancer. 2014; 50(2):406-410
Doi: 10.1016/j.ejca.2013.09.014
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Heidenreich, B; Nagore, E; Rachakonda, PS; Garcia-Casado, Z; Requena, C; Traves, V; Becker, J; Soufir, N; Hemminki, K; Kumar, R
Telomerase reverse transcriptase promoter mutations in primary cutaneous melanoma.
Nat Commun. 2014; 5(5):3401-3401
Doi: 10.1038/ncomms4401
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Yeh, I; Mully, TW; Wiesner, T; Vemula, SS; Mirza, SA; Sparatta, AJ; McCalmont, TH; Bastian, BC; LeBoit, PE
Ambiguous melanocytic tumors with loss of 3p21.
Am J Surg Pathol. 2014; 38(8): 1088-1095.
Doi: 10.1097/PAS.0000000000000209
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2013
Aigner, B; Plötz, SG; Schaller, G
Triple-negative breast cancer possibly transforming into malignant melanoma due to targeted therapy? A case report and review of literature.
Wien Med Wochenschr. 2013; 163(21-22): 495-498.
Doi: 10.1007/s10354-013-0242-0
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Griewank, KG; Westekemper, H; Murali, R; Mach, M; Schilling, B; Wiesner, T; Schimming, T; Livingstone, E; Sucker, A; Grabellus, F; Metz, C; Süsskind, D; Hillen, U; Speicher, MR; Woodman, SE; Steuhl, KP; Schadendorf, D
Conjunctival melanomas harbor BRAF and NRAS mutations and copy number changes similar to cutaneous and mucosal melanomas.
Clin Cancer Res. 2013; 19(12):3143-3152
Doi: 10.1158/1078-0432.CCR-13-0163
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Hacker, E; Nagore, E; Cerroni, L; Woods, SL; Hayward, NK; Chapman, B; Montgomery, GW; Soyer, HP; Whiteman, DC;
NRAS and BRAF Mutations in Cutaneous Melanoma and the Association with MC1R Genotype: Findings from Spanish and Austrian Populations.
J INVEST DERMATOL. 2013; 133(4): 1027-1033.
Doi: 10.1038/jid.2012.385
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Kerl, K; Leo, S; Hesse, R; Hesse, B; Gabriela, P; Requena, L; Wiesner, T; Kutzner, H
Two-dimensional visualization of multicolor FISH-generated data as a helpful tool for the analysis and understanding of cytogenetic and chromosomal alterations in melanocytic lesions.
Am J Dermatopathol. 2013; 35(2):151-158
Doi: 10.1097/DAD.0b013e318265fd08
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Murali, R; Wiesner, T; Scolyer, RA
Tumours associated with BAP1 mutations.
Pathology. 2013; 45(2):116-126
Doi: 10.1097/PAT.0b013e32835d0efb
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Murali, R; Wilmott, JS; Jakrot, V; Al-Ahmadie, HA; Wiesner, T; McCarthy, SW; Thompson, JF; Scolyer, RA
BAP1 expression in cutaneous melanoma: a pilot study.
Pathology. 2013; 45(6): 606-609.
Doi: 10.1097/PAT.0b013e3283653818
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Richtig, E; Schrama, D; Ugurel, S; Fried, I; Niederkorn, A; Massone, C; Becker, JC
BRAF mutation analysis of only one single metastatic lesion can restrict the treatment of melanoma - a case report.
Br J Dermatol. 2013; 168(2):428-430
Doi: 10.1111/j.1365-2133.2012.11121.x
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Wiesner, T; Fried, I; Cerroni, L; Kutzner, H
Molecular biology methods to improve diagnosis and prognosis of melanocytic tumors.
J Dtsch Dermatol Ges. 2013; 11 Suppl 4(6):19-24
Doi: 10.1111/ddg.12083_supp
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2012
Flaherty, KT; Robert, C; Hersey, P; Nathan, P; Garbe, C; Milhem, M; Demidov, LV; Hassel, JC; Rutkowski, P; Mohr, P; Dummer, R; Trefzer, U; Larkin, JMG; Utikal, J; Dreno, B; Nyakas, M; Middleton, MR; Becker, JC; Casey, M; Sherman, LJ; Wu, FS; Ouellet, D; Martin, AM; Patel, K; Schadendorf, D;
Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma.
N ENGL J MED. 2012; 367(2): 107-114.
Doi: 10.1056/NEJMoa1203421
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Kerl, K; Kempf, W; Kamarashev, J; Spallone, G; Braun, R; Wiesner, T; French, LE; Dummer, R
Constitutional intraepidermal ascent of melanocytes: a potential pitfall in the diagnosis of melanocytic lesions.
Arch Dermatol. 2012; 148(2):235-238
Doi: 10.1001/archdermatol.2011.2026
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Kerl, K; Palmedo, G; Wiesner, T; Mentzel, T; Rütten, A; Schärer, L; Paredes, B; Hantschke, M; Kutzner, H
A proposal for improving multicolor FISH sensitivity in the diagnosis of malignant melanoma using new combined criteria.
Am J Dermatopathol. 2012; 34(6):580-585
Doi: 10.1097/DAD.0b013e3182433f3a
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Kutzner, H; Metzler, G; Argenyi, Z; Requena, L; Palmedo, G; Mentzel, T; Rütten, A; Hantschke, M; Paredes, BE; Schärer, L; Hesse, B; El-Shabrawi-Caelen, L; Shabrawi-Caelen, LE; Fried, I; Kerl, H; Lorenzo, C; Murali, R; Wiesner, T
Histological and genetic evidence for a variant of superficial spreading melanoma composed predominantly of large nests.
Mod Pathol. 2012; 25(6):838-845
Doi: 10.1038/modpathol.2012.35
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Liu, SJ; Tetzlaff, MT; Liu, AH; Liegl-Atzwanger, B; Guo, J; Xu, XW;
Loss of microRNA-205 expression is associated with melanoma progression.
Lab Invest. 2012; 92(7):1084-1096
Doi: 10.1038/labinvest.2012.62
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Murali, R; Wiesner, T; Rosenblum, MK; Bastian, BC
GNAQ and GNA11 mutations in melanocytomas of the central nervous system.
Acta Neuropathol. 2012; 123(3): 457-459.
Doi: 10.1007/s00401-012-0948-x
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Wiesner, T; Fried, I; Ulz, P; Stacher, E; Popper, H; Murali, R; Kutzner, H; Lax, S; Smolle-Jüttner, F; Geigl, JB; Speicher, MR
Toward an improved definition of the tumor spectrum associated with BAP1 germline mutations.
J Clin Oncol. 2012; 30(32):e337-e340
Doi: 10.1200/JCO.2011.41.2965
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2011
Karki, P; Li, X; Schrama, D; Fliegel, L
B-Raf Associates with and Activates the NHE1 Isoform of the Na+/H+ Exchanger.
J Biol Chem. 2011; 286(15): 13096-13105.
Doi: 10.1074/jbc.M110.165134
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Schrama, D; Scherer, D; Schneider, M; Zapatka, M; Bröcker, EB; Schadendorf, D; Ugurel, S; Kumar, R; Becker, JC
ERCC5 p.Asp1104His and ERCC2 p.Lys751Gln Polymorphisms Are Independent Prognostic Factors for the Clinical Course of Melanoma.
J Invest Dermatol. 2011; 131(6):1280-1290
Doi: 10.1038/jid.2011.35
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Vergier, B; Prochazkova-Carlotti, M; de la Fouchardière, A; Cerroni, L; Massi, D; De Giorgi, V; Bailly, C; Wesselmann, U; Karlseladze, A; Avril, MF; Jouary, T; Merlio, JP
Fluorescence in situ hybridization, a diagnostic aid in ambiguous melanocytic tumors: European study of 113 cases.
Mod Pathol. 2011; 24(5):613-623
Doi: 10.1038/modpathol.2010.228
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2010
Gaiser, T; Kutzner, H; Palmedo, G; Siegelin, MD; Wiesner, T; Bruckner, T; Hartschuh, W; Enk, AH; Becker, MR
Classifying ambiguous melanocytic lesions with FISH and correlation with clinical long-term follow up.
Mod Pathol. 2010; 23(3):413-419
Doi: 10.1038/modpathol.2009.177
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Schrama, D; Kneitz, H; Willmes, C; Adam, C; Houben, R; Becker, JC
Lack of correlation between IGFBP7 expression and BRAF mutational status in melanoma.
J Invest Dermatol. 2010; 130(3):897-898
Doi: 10.1038/jid.2009.304
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Terheyden, P; Houben, R; Pajouh, P; Thorns, C; Zillikens, D; Becker, JC
Response to imatinib mesylate depends on the presence of the V559A-mutated KIT oncogene.
J Invest Dermatol. 2010; 130(1):314-316
Doi: 10.1038/jid.2009.197
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Van Raamsdonk, CD; Griewank, KG; Crosby, MB; Garrido, MC; Vemula, S; Wiesner, T; Obenauf, AC; Wackernagel, W; Green, G; Bouvier, N; Sozen, MM; Baimukanova, G; Roy, R; Heguy, A; Dolgalev, I; Khanin, R; Busam, K; Speicher, MR; O'Brien, J; Bastian, BC
Mutations in GNA11 in Uveal Melanoma.
N ENGL J MED. 2010; 363(23): 2191-2199.
Doi: 10.1056/NEJMoa1000584
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2009
Hofmann, UB; Kauczok-Vetter, CS; Houben, R; Becker, JC
Overexpression of the KIT/SCF in uveal melanoma does not translate into clinical efficacy of imatinib mesylate.
Clin Cancer Res. 2009; 15(1):324-329
Doi: 10.1158/1078-0432.CCR-08-2243
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Ugurel, S; Utikal, J; Becker, JC
Tumor biomarkers in melanoma.
Cancer Control. 2009; 16(3):219-224
Doi: 10.1177/107327480901600303
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Zalaudek, I; Meiklejohn, W; Argenziano, G; Thurber, AE; Sturm, RA
White nevi and red melanomas: association with the RHC phenotype of the MC1R gene.
J Invest Dermatol. 2009; 129(5):1305-1307
Doi: 10.1038/jid.2008.378
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2008
Houben, R; Vetter-Kauczok, CS; Ortmann, S; Rapp, UR; Broecker, EB; Becker, JC
Phospho-ERK staining is a poor indicator of the mutational status of BRAF and NRAS in human melanoma.
J Invest Dermatol. 2008; 128(8):2003-2012
Doi: 10.1038/jid.2008.30
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Seidl, H; Weger, W; Wolf, P; Kerl, H; Schaider, H
Lack of oncogenic mutations in the c-Met catalytic tyrosine kinase domain in acral lentiginous melanoma.
Int J Dermatol. 2008; 47(12): 1327-1329.
Doi: 10.1111/j.1365-4632.2008.03818.x
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