Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Navigation/Suche

• Forscher*innen.
• Institutionen.
• Projekte.
• Publikationen.
• Partner.
• Geldgeber.
• Ausstattung.
• Knowhow.
• Forschungsfelder.

Publikationen

Suchbegriffe: MEK INHIBITOR, . Treffer: 17

2020

Dummer, R; Lebbé, C; Atkinson, V; Mandalà, M; Nathan, PD; Arance, A; Richtig, E; Yamazaki, N; Robert, C; Schadendorf, D; Tawbi, HA; Ascierto, PA; Ribas, A; Flaherty, KT; Pakhle, N; Campbell, CD; Gusenleitner, D; Masood, A; Brase, JC; Gasal, E; Long, GV Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i.
Nat Med. 2020; 26(10): 1557-1563. Doi: 10.1038/s41591-020-1082-2
Web of Science PubMed FullText FullText_MUG

 

Garbe, C; Amaral, T; Peris, K; Hauschild, A; Arenberger, P; Bastholt, L; Bataille, V; Del, Marmol, V; Dréno, B; Fargnoli, MC; Grob, JJ; Höller, C; Kaufmann, R; Lallas, A; Lebbé, C; Malvehy, J; Middleton, M; Moreno-Ramirez, D; Pellacani, G; Saiag, P; Stratigos, AJ; Vieira, R; Zalaudek, I; Eggermont, AMM, , European, Dermatology, Forum, (EDF), the, European, Association, of, Dermato-Oncology, (EADO), and, the, European, Organization, for, Research, and, Treatment, of, Cancer, (EORTC) European consensus-based interdisciplinary guideline for melanoma. Part 2: Treatment - Update 2019.
Eur J Cancer. 2020; 126:159-177 Doi: 10.1016/j.ejca.2019.11.015
Web of Science PubMed FullText FullText_MUG

 

McGregor, GH; Campbell, AD; Fey, SK; Tumanov, S; Sumpton, D; Blanco, GR; Mackay, G; Nixon, C; Vazquez, A; Sansom, OJ; Kamphorst, JJ Targeting the Metabolic Response to Statin-Mediated Oxidative Stress Produces a Synergistic Antitumor Response.
Cancer Res. 2020; 80(2):175-188 Doi: 10.1158/0008-5472.CAN-19-0644
Web of Science PubMed FullText FullText_MUG

 

Woltsche, N; Kruger, MA; Weger, M; Wolf, IH; Seidel, G Intravitreal Steroid Treatment for Uveitis Associated with Dabrafenib and Trametinib for Metastatic Cutaneous Melanoma.
Ocul Immunol Inflamm. 2020; 1-3 Doi: 10.1080/09273948.2019.1695860
Web of Science PubMed FullText FullText_MUG

 

2017

Kandolf Sekulovic, L; Peris, K; Hauschild, A; Stratigos, A; Grob, JJ; Nathan, P; Dummer, R; Forsea, AM; Hoeller, C; Gogas, H; Demidov, L; Lebbe, C; Blank, C; Olah, J; Bastholt, L; Herceg, D; Neyns, B; Vieira, R; Hansson, J; Rutkowski, P; Krajsova, I; Bylaite-Bucinskiene, M; Zalaudek, I; Maric-Brozic, J; Babovic, N; Banjin, M; Putnik, K; Weinlich, G; Todorovic, V; Kirov, K; Ocvirk, J; Zhukavets, A; Kukushkina, M; De La Cruz Merino, L; Ymeri, A; Risteski, M; Garbe, C More than 5000 patients with metastatic melanoma in Europe per year do not have access to recommended first-line innovative treatments.
Eur J Cancer. 2017; 75(4):313-322 Doi: 10.1016/j.ejca.2017.01.012
Web of Science PubMed FullText FullText_MUG

 

Richtig, G; Hoeller, C; Kashofer, K; Aigelsreiter, A; Heinemann, A; Kwong, LN; Pichler, M; Richtig, E Beyond the BRAF^V600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.
Br J Dermatol. 2017; 177(4):936-944 Doi: 10.1111/bjd.15436
Web of Science PubMed FullText FullText_MUG

 

Rouf, R; MacFarlane, EG; Takimoto, E; Chaudhary, R; Nagpal, V; Rainer, PP; Bindman, JG; Gerber, EE; Bedja, D; Schiefer, C; Miller, KL; Zhu, GS; Myers, L; Amat-Alarcon, N; Lee, DI; Koitabashi, N; Judge, DP; Kass, DA; Dietz, HC Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice
JCI INSIGHT. 2017; 2(15): e91588 Doi: 10.1172/jci.insight.91588 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2016

Richtig, G; Aigelsreiter, A; Kashofer, K; Talakic, E; Kupsa, R; Schaider, H; Richtig, E Two Case Reports of Rare BRAF Mutations in Exon 11 and Exon 15 with Discussion of Potential Treatment Options.
Case Rep Oncol. 2016; 9(3):543-546 Doi: 10.1159/000449125 (- Case Report) [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2014

Goldinger, SM; Zimmer, L; Schulz, C; Ugurel, S; Hoeller, C; Kaehler, KC; Schadendorf, D; Hassel, JC; Becker, J; Hauschild, A; Dummer, R; Dermatology Cooperative Oncology Group (DeCOG) Upstream mitogen-activated protein kinase (MAPK) pathway inhibition: MEK inhibitor followed by a BRAF inhibitor in advanced melanoma patients.
Eur J Cancer. 2014; 50(2):406-410 Doi: 10.1016/j.ejca.2013.09.014
Web of Science PubMed FullText FullText_MUG

 

2013

Lin, S; Hoffmann, K; Xiao, Z; Jin, N; Galli, U; Mohr, E; Büchler, MW; Schemmer, P MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma.
Cancer Cell Int. 2013; 13(1):3-3 Doi: 10.1186/1475-2867-13-3 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Menon, DR; Wels, C; Bonyadi Rad, E; Joshi, S; Knausz, H; Lade-Keller, J; Brandner, JM; Schaider, H TGF-β1 and TNF-α differentially regulate Twist1 mediated resistance towards BRAF/MEK inhibition in melanoma.
Pigment Cell Melanoma Res. 2013; 26(6):912-916 Doi: 10.1111/pcmr.12139
Web of Science PubMed FullText FullText_MUG

 

2012

Kocić, J; Villar, V; Krstić, A; Santibanez, JF SKIP Downregulation Increases TGF-β1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes.
Scientifica (Cairo). 2012; 2012:861647-861647 Doi: 10.6064/2012/861647 [OPEN ACCESS]
PubMed FullText FullText_MUG

 

2010

Santibáñez, JF; Kocić, J; Fabra, A; Cano, A; Quintanilla, M Rac1 modulates TGF-beta1-mediated epithelial cell plasticity and MMP9 production in transformed keratinocytes.
FEBS Lett. 2010; 584(11): 2305-2310. Doi: 10.1016/j.febslet.2010.03.042 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2003

Moré, E; Fellner, T; Doppelmayr, H; Hauser-Kronberger, C; Dandachi, N; Obrist, P; Sandhofer, F; Paulweber, B Activation of the MAP kinase pathway induces chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) expression in human breast cancer cell lines.
J Endocrinol. 2003; 176(1): 83-94. Doi: 10.1677/joe.0.1760083 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Patz, S; Wirth, MJ; Gorba, T; Klostermann, O; Wahle, P Neuronal activity and neurotrophic factors regulate GAD-65/67 mRNA and protein expression in organotypic cultures of rat visual cortex.
Eur J Neurosci. 2003; 18(1):1-12 Doi: 10.1046/j.1460-9568.2003.02702.x
Web of Science PubMed FullText FullText_MUG

 

2000

Marschitz, I; Lechner, J; Mosser, I; Dander, M; Montesano, R; Schramek, H Differential expression of cell-cell adhesion proteins and cyclin D in MEK1-transdifferentiated MDCK cells.
Am J Physiol Cell Physiol. 2000; 279(5):C1472-C1482 Doi: 10.1152/ajpcell.2000.279.5.C1472 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

1999

Stepan, VM; Dickinson, CJ; del Valle, J; Matsushima, M; Todisco, A Cell type-specific requirement of the MAPK pathway for the growth factor action of gastrin.
Am J Physiol. 1999; 276(6 Pt 1):G1363-G1372 Doi: 10.1152/ajpgi.1999.276.6.G1363 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

↑ Seitenanfang / Navigation

© Med Uni Graz • Impressum