Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: LUNG NEOPLASMS - GENETICS , . Treffer: 52

2022

Zhang, H; Zhu, X; Friesen, TJ; Kwak, JW; Pisarenko, T; Mekvanich, S; Velasco, MA; Randolph, TW; Kargl, J; Houghton, AM Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils.
J Clin Invest. 2022; 132(22): Doi: 10.1172/JCI153643 [OPEN ACCESS]
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2019

Washetine, K; Heeke, S; Ribeyre, C; Bourreau, C; Normand, C; Blons, H; Laurent-Puig, P; Mulot, C; Clermont, D; David, M; Clément, B; Dagher, G; Hofman, P DNAshell Protects DNA Stored at Room Temperature for Downstream Next-Generation Sequencing Studies.
Biopreserv Biobank. 2019; 17(4): 352-354. Doi: 10.1089/bio.2018.0129
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2018

Gandhi, L; Rodríguez-Abreu, D; Gadgeel, S; Esteban, E; Felip, E; De Angelis, F; Domine, M; Clingan, P; Hochmair, MJ; Powell, SF; Cheng, SY; Bischoff, HG; Peled, N; Grossi, F; Jennens, RR; Reck, M; Hui, R; Garon, EB; Boyer, M; Rubio-Viqueira, B; Novello, S; Kurata, T; Gray, JE; Vida, J; Wei, Z; Yang, J; Raftopoulos, H; Pietanza, MC; Garassino, MC; KEYNOTE-189 Investigators Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.
N Engl J Med. 2018; 378(22): 2078-2092. Doi: 10.1056/NEJMoa1801005
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Gantenbein, N; Bernhart, E; Anders, I; Golob-Schwarzl, N; Krassnig, S; Wodlej, C; Brcic, L; Lindenmann, J; Fink-Neuboeck, N; Gollowitsch, F; Stacher-Priehse, E; Asslaber, M; Gogg-Kamerer, M; Rolff, J; Hoffmann, J; Silvestri, A; Regenbrecht, C; Reinhard, C; Pehserl, AM; Pichler, M; Sokolova, O; Naumann, M; Mitterer, V; Pertschy, B; Bergler, H; Popper, H; Sattler, W; Haybaeck, J Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression.
Eur J Cancer. 2018; 101(4):165-180 Doi: 10.1016/j.ejca.2018.07.001 [OPEN ACCESS]
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Zhong, Q; Wagner, U; Kurt, H; Molinari, F; Cathomas, G; Komminoth, P; Barman-Aksözen, J; Schneider-Yin, X; Rey, JP; Vassella, E; Rogel, U; Diebold, J; McKee, T; Jochum, W; Kashofer, K; Hofman, P; Zischka, M; Moch, H; Rechsteiner, M; Wild, PJ Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing.
Pathol Res Pract. 2018; 214(7):957-963 Doi: 10.1016/j.prp.2018.05.020
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2017

Arzt, L; Halbwedl, I; Gogg-Kamerer, M; Popper, HH Signal Transducer and Activator of Transcription 1 (STAT1) Knock-down Induces Apoptosis in Malignant Pleural Mesothelioma.
Pathol Oncol Res. 2017; 23(3):595-605 Doi: 10.1007/s12253-016-0157-3 [OPEN ACCESS]
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Dandachi, N; Tiran, V; Lindenmann, J; Brcic, L; Fink-Neuboeck, N; Kashofer, K; Absenger, G; Bezan, A; Cote, RJ; Datar, R; Balic, M Frequency and clinical impact of preoperative circulating tumor cells in resectable non-metastatic lung adenocarcinomas.
Lung Cancer. 2017; 113(46):152-157 Doi: 10.1016/j.lungcan.2017.10.003
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Joshi, PK; Pirastu, N; Kentistou, KA; Fischer, K; Hofer, E; Schraut, KE; Clark, DW; Nutile, T; Barnes, CLK; Timmers, PRHJ; Shen, X; Gandin, I; McDaid, AF; Hansen, TF; Gordon, SD; Giulianini, F; Boutin, TS; Abdellaoui, A; Zhao, W; Medina-Gomez, C; Bartz, TM; Trompet, S; Lange, LA; Raffield, L; van der Spek, A; Galesloot, TE; Proitsi, P; Yanek, LR; Bielak, LF; Payton, A; Murgia, F; Concas, MP; Biino, G; Tajuddin, SM; Seppälä, I; Amin, N; Boerwinkle, E; Børglum, AD; Campbell, A; Demerath, EW; Demuth, I; Faul, JD; Ford, I; Gialluisi, A; Gögele, M; Graff, M; Hingorani, A; Hottenga, JJ; Hougaard, DM; Hurme, MA; Ikram, MA; Jylhä, M; Kuh, D; Ligthart, L; Lill, CM; Lindenberger, U; Lumley, T; Mägi, R; Marques-Vidal, P; Medland, SE; Milani, L; Nagy, R; Ollier, WER; Peyser, PA; Pramstaller, PP; Ridker, PM; Rivadeneira, F; Ruggiero, D; Saba, Y; Schmidt, R; Schmidt, H; Slagboom, PE; Smith, BH; Smith, JA; Sotoodehnia, N; Steinhagen-Thiessen, E; van Rooij, FJA; Verbeek, AL; Vermeulen, SH; Vollenweider, P; Wang, Y; Werge, T; Whitfield, JB; Zonderman, AB; Lehtimäki, T; Evans, MK; Pirastu, M; Fuchsberger, C; Bertram, L; Pendleton, N; Kardia, SLR; Ciullo, M; Becker, DM; Wong, A; Psaty, BM; van Duijn, CM; Wilson, JG; Jukema, JW; Kiemeney, L; Uitterlinden, AG; Franceschini, N; North, KE; Weir, DR; Metspalu, A; Boomsma, DI; Hayward, C; Chasman, D; Martin, NG; Sattar, N; Campbell, H; Esko, T; Kutalik, Z; Wilson, JF Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.
Nat Commun. 2017; 8(1):910-910 Doi: 10.1038/s41467-017-00934-5 [OPEN ACCESS]
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Mairinger, FD; Vollbrecht, C; Flom, E; Christoph, DC; Schmid, KW; Kollmeier, J; Popper, HH; Mairinger, T; Walter, RFH Folic acid phenotype (FAP) is a superior biomarker predicting response to pemetrexed-based chemotherapy in malignant pleural mesothelioma.
Oncotarget. 2017; 8(23):37502-37510 Doi: 10.18632/oncotarget.16398 [OPEN ACCESS]
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Mehta, AK; Hua, K; Whipple, W; Nguyen, MT; Liu, CT; Haybaeck, J; Weidhaas, J; Settleman, J; Singh, A Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells.
Sci Signal. 2017; 10(496): Doi: 10.1126/scisignal.aam6291 [OPEN ACCESS]
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Wohlkoenig, C; Leithner, K; Olschewski, A; Olschewski, H; Hrzenjak, A TR3 is involved in hypoxia-induced apoptosis resistance in lung cancer cells downstream of HIF-1α.
Lung Cancer. 2017; 111(3):15-22 Doi: 10.1016/j.lungcan.2017.06.013
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2016

Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 Doi: 10.18632/oncotarget.9418 [OPEN ACCESS]
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Busch, SE; Hanke, ML; Kargl, J; Metz, HE; MacPherson, D; Houghton, AM Lung Cancer Subtypes Generate Unique Immune Responses.
J Immunol. 2016; 197(11):4493-4503 Doi: 10.4049/jimmunol.1600576 [OPEN ACCESS]
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Leithner, K; Hirschmugl, B; Li, Y; Tang, B; Papp, R; Nagaraj, C; Stacher, E; Stiegler, P; Lindenmann, J; Olschewski, A; Olschewski, H; Hrzenjak, A TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers.
PLoS One. 2016; 11(6):e0157453-e0157453 Doi: 10.1371/journal.pone.0157453 [OPEN ACCESS]
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Metz, HE; Kargl, J; Busch, SE; Kim, KH; Kurland, BF; Abberbock, SR; Randolph-Habecker, J; Knoblaugh, SE; Kolls, JK; White, MF; Houghton, AM Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.
Proc Natl Acad Sci U S A. 2016; 113(31):8795-8800 Doi: 10.1073/pnas.1601989113 [OPEN ACCESS]
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Popper, HH Progression and metastasis of lung cancer.
Cancer Metastasis Rev. 2016; 35(1):75-91 Doi: 10.1007/s10555-016-9618-0 [OPEN ACCESS]
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2015

Fischer, C; Leithner, K; Wohlkoenig, C; Quehenberger, F; Bertsch, A; Olschewski, A; Olschewski, H; Hrzenjak, A Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization.
Mol Cancer. 2015; 14(8):4-4 Doi: 10.1186/1476-4598-14-4 [OPEN ACCESS]
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Kessler, SM; Laggai, S; Barghash, A; Schultheiss, CS; Lederer, E; Artl, M; Helms, V; Haybaeck, J; Kiemer, AK IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.
Cell Death Dis. 2015; 6(1):e1894-e1894 Doi: 10.1038/cddis.2015.241 [OPEN ACCESS]
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Laszlo, V; Hoda, MA; Garay, T; Pirker, C; Ghanim, B; Klikovits, T; Dong, YW; Rozsas, A; Kenessey, I; Szirtes, I; Grusch, M; Jakopovic, M; Samarzija, M; Brcic, L; Kern, I; Rozman, A; Popper, H; Zöchbauer-Müller, S; Heller, G; Altenberger, C; Ziegler, B; Klepetko, W; Berger, W; Dome, B; Hegedus, B Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.
J Pathol. 2015; 237(2):203-214 Doi: 10.1002/path.4567
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Popper, HH Lung adenocarcinomas: comparison between mice and men.
Methods Mol Biol. 2015; 1267(2):19-43 Doi: 10.1007/978-1-4939-2297-0_2
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Ramlau, R; Cufer, T; Berzinec, P; Dziadziuszko, R; Olszewski, W; Popper, H; Bajcic, P; Dusšk, L; Zbozinkova, Z; Pirker, R; INSIGHT study team Epidermal Growth Factor Receptor Mutation-Positive Non-Small-Cell Lung Cancer in the Real-World Setting in Central Europe: The INSIGHT Study.
J Thorac Oncol. 2015; 10(9):1370-1374 Doi: 10.1097/JTO.0000000000000621 [OPEN ACCESS]
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Zopf, A; Raim, R; Danzer, M; Niklas, N; Spilka, R; Pröll, J; Gabriel, C; Nechansky, A; Roucka, M Introduction of the hybcell-based compact sequencing technology and comparison to state-of-the-art methodologies for KRAS mutation detection.
Biotechniques. 2015; 58(3):126-134 Doi: 10.2144/000114264 [OPEN ACCESS]
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2014

Arzt, L; Quehenberger, F; Halbwedl, I; Mairinger, T; Popper, HH BAP1 protein is a progression factor in malignant pleural mesothelioma.
Pathol Oncol Res. 2014; 20(1):145-151 Doi: 10.1007/s12253-013-9677-2
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Ma, X; Rousseau, V; Sun, H; Lantuejoul, S; Filipits, M; Pirker, R; Popper, H; Mendiboure, J; Vataire, AL; Le Chevalier, T; Soria, JC; Brambilla, E; Dunant, A; Hainaut, P; IALT-Bio working group Significance of TP53 mutations as predictive markers of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer.
Mol Oncol. 2014; 8(3):555-564 Doi: 10.1016/j.molonc.2013.12.015 [OPEN ACCESS]
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Pircher, A; Manzl, C; Fiegl, M; Popper, H; Pirker, R; Hilbe, W Overcoming resistance to first generation EGFR TKIs with cetuximab in combination with chemotherapy in an EGFR mutated advanced stage NSCLC patient.
Lung Cancer. 2014; 83(3): 408-410. Doi: 10.1016/j.lungcan.2013.12.007 (- Case Report)
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Schelch, K; Hoda, MA; Klikovits, T; Münzker, J; Ghanim, B; Wagner, C; Garay, T; Laszlo, V; Setinek, U; Dome, B; Filipits, M; Pirker, C; Heffeter, P; Selzer, E; Tovari, J; Torok, S; Kenessey, I; Holzmann, K; Grasl-Kraupp, B; Marian, B; Klepetko, W; Berger, W; Hegedus, B; Grusch, M Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.
Am J Respir Crit Care Med. 2014; 190(7):763-772 Doi: 10.1164/rccm.201404-0658OC
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2013

Murali, R; Wiesner, T; Scolyer, RA Tumours associated with BAP1 mutations.
Pathology. 2013; 45(2):116-126 Doi: 10.1097/PAT.0b013e32835d0efb
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2012

Brcic, L; Sherer, CK; Shuai, Y; Hornick, JL; Chirieac, LR; Dacic, S Morphologic and clinicopathologic features of lung squamous cell carcinomas expressing Sox2.
Am J Clin Pathol. 2012; 138(5): 712-718. Doi: 10.1309/AJCP05TTWQTWNLTN [OPEN ACCESS]
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Musteanu, M; Blaas, L; Zenz, R; Svinka, J; Hoffmann, T; Grabner, B; Schramek, D; Kantner, HP; Müller, M; Kolbe, T; Rülicke, T; Moriggl, R; Kenner, L; Stoiber, D; Penninger, JM; Popper, H; Casanova, E; Eferl, R A mouse model to identify cooperating signaling pathways in cancer.
Nat Methods. 2012; 9(9):897-900 Doi: 10.1038/nmeth.2130
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Pitroda, SP; Zhou, T; Sweis, RF; Filippo, M; Labay, E; Beckett, MA; Mauceri, HJ; Liang, H; Darga, TE; Perakis, S; Khan, SA; Sutton, HG; Zhang, W; Khodarev, NN; Garcia, JG; Weichselbaum, RR Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
PLoS One. 2012; 7(10): e46104-e46104. Doi: 10.1371/journal.pone.0046104 [OPEN ACCESS]
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2011

Kriegshäuser, G; Fabjani, G; Ziegler, B; Zöchbauer-Müller, S; End, A; Zeillinger, R Biochip-based detection of KRAS mutation in non-small cell lung cancer.
Int J Mol Sci. 2011; 12(12): 8530-8538. Doi: 10.3390/ijms12128530 [OPEN ACCESS]
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2009

Gebeshuber, CA; Zatloukal, K; Martinez, J miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis.
EMBO Rep. 2009; 10(4): 400-405. Doi: 10.1038/embor.2009.9 [OPEN ACCESS]
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Kamlah, F; Eul, BG; Li, S; Lang, N; Marsh, LM; Seeger, W; Grimminger, F; Rose, F; Hänze, J Intravenous injection of siRNA directed against hypoxia-inducible factors prolongs survival in a Lewis lung carcinoma cancer model.
Cancer Gene Ther. 2009; 16(3): 195-205. Doi: 10.1038/cgt.2008.71 [OPEN ACCESS]
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Kramer, A; Gattenlohner, S; Neben, K CUP syndrome: molecular pathogenesis and biology
Pathologe. 2009; 30(2):117-124 Doi: 10.1007/s00292-008-1114-z
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Pfragner, R; Behmel, A; Höger, H; Beham, A; Ingolic, E; Stelzer, I; Svejda, B; Moser, VA; Obenauf, AC; Siegl, V; Haas, O; Niederle, B Establishment and characterization of three novel cell lines - P-STS, L-STS, H-STS - derived from a human metastatic midgut carcinoid.
ANTICANCER RES. 2009; 29(6): 1951-1961. [OPEN ACCESS]
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2008

Popper, HH; European Working Groups for Molecular Pathology and Pulmonary Pathology Molecular signatures of lung and pleural tumors: joint symposium of the European Working Groups for Molecular Pathology and Pulmonary Pathology, 21st European Congress of Pathology.
Arch Pathol Lab Med. 2008; 132(10): 1549-1550. Doi: 10.5858/2008-132-1549-MSOLAP [OPEN ACCESS]
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Sitić, S; Mirt-Dabić, M; Brcić, L; Juros, Z; Hutinec, Z; Kruslin, B DNA ploidy in thymoma and associated multiple primary malignancies in the same patient.
Acta Clin Croat. 2008; 47(3):155-159 (- Case Report) [OPEN ACCESS]
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2004

Petzmann, S; Ullmann, R; Halbwedl, I; Popper, HH Analysis of chromosome-11 aberrations in pulmonary and gastrointestinal carcinoids: an array comparative genomic hybridization-based study.
VIRCHOWS ARCHIV. 2004; 445(2): 151-159. Doi: 10.1007/s00428-004-1052-y
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Stacher, E; Ullmann, R; Halbwedl, I; Gogg-Kammerer, M; Boccon-Gibod, L; Nicholson, AG; Sheppard, MN; Carvalho, L; Franca, MT; Macsweeney, F; Morresi-Hauf, A; Popper, HH Atypical goblet cell hyperplasia in congenital cystic adenomatoid malformation as a possible preneoplasia for pulmonary adenocarcinoma in childhood: A genetic analysis.
HUM PATHOL. 2004; 35(5): 565-570. Doi: 10.1016%2Fj.humpath.2004.01.008 [OPEN ACCESS]
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Ullmann, R; Morbini, P; Halbwedl, I; Bongiovanni, M; Gogg-Kammerer, M; Papotti, M; Gabor, S; Renner, H; Popper, HH Protein expression profiles in adenocarcinomas and squamous cell carcinomas of the lung generated using tissue microarrays.
J PATHOL. 2004; 203(3): 798-807. Doi: 10.1002/path.1584
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2003

Haedicke, W; Popper, HH; Buck, CR; Zatloukal, K Automated evaluation and normalization of immunohistochemistry on tissue microarrays with a DNA microarray scanner.
Biotechniques. 2003; 35(1):164-168 Doi: 10.2144/03351md04 [OPEN ACCESS]
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Ullmann, R; Bongiovanni, M; Halbwedl, I; Fraire, AE; Cagle, PT; Mori, M; Papotti, M; Popper, HH Is high-grade adenomatous hyperplasia an early bronchioloalveolar adenocarcinoma?
J Pathol. 2003; 201(3):371-376 Doi: 10.1002/path.1460
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Ullmann, R; Bongiovanni, M; Halbwedl, I; Petzmann, S; Gogg-Kammerer, M; Sapino, A; Papotti, M; Bussolati, G; Popper, HH Bronchiolar columnar cell dysplasia--genetic analysis of a novel preneoplastic lesion of peripheral lung.
Virchows Arch. 2003; 442(5):429-436 Doi: 10.1007/s00428-003-0797-z
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2001

Petzmann, S; Ullmann, R; Klemen, H; Renner, H; Popper, HH Loss of heterozygosity on chromosome arm 11q in lung carcinoids.
Hum Pathol. 2001; 32(3):333-338 Doi: 10.1053/hupa.2001.22762
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2000

Speicher, MR; Petersen, S; Uhrig, S; Jentsch, I; Fauth, C; Eils, R; Petersen, I Analysis of chromosomal alterations in non-small cell lung cancer by multiplex-FISH, comparative genomic hybridization, and multicolor bar coding.
Lab Invest. 2000; 80(7):1031-1041 Doi: 10.1038/labinvest.3780108 [OPEN ACCESS]
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1999

Gattenlohner, S; Muller-Hermelink, HK; Marx, A Transcription of the nude gene (WHN) in human normal organs and mediastinal and pulmonary tumors.
Pathol Res Pract. 1999; 195(8):571-574 Doi: 10.1016/S0344-0338(99)80007-7
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Sigl, E; Behmel, A; Henn, T; Wirnsberger, G; Weinhausl, A; Kaserer, K; Niederle, B; Pfragner, R Cytogenetic and CGH studies of four neuroendocrine tumors and tumor-derived cell lines of a patient with multiple endocrine neoplasia type 1.
Int J Oncol. 1999; 15(1):41-51 Doi: 10.3892/ijo.15.1.41 (- Case Report)
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1998

Ullmann, R; Schwendel, A; Klemen, H; Wolf, G; Petersen, I; Popper, HH Unbalanced chromosomal aberrations in neuroendocrine lung tumors as detected by comparative genomic hybridization.
Hum Pathol. 1998; 29(10):1145-1149 Doi: 10.1016%2FS0046-8177%2898%2990428-2
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1996

Hrascan, R; Pavelic, K; Pavicic, D; Krizanac, S; Stajcer-Sittic, V; Pecur, L; Spaventi, S; Klimpfinger, M; Pavelic, J Concomitant point mutation of tumor suppressor gene p53 and oncogene c-N-ras in malignant neuroendocrine pancreatic tumor.
Anticancer Res. 1996; 16(6B):3761-3766 (- Case Report)
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1994

Ried, T; Petersen, I; Holtgreve-Grez, H; Speicher, MR; Schröck, E; du Manoir, S; Cremer, T Mapping of multiple DNA gains and losses in primary small cell lung carcinomas by comparative genomic hybridization.
Cancer Res. 1994; 54(7):1801-1806 [OPEN ACCESS]
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