Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: LIVER - ENZYMOLOGY , . Treffer: 65

2017

Melvin, AJ; Warshaw, M; Compagnucci, A; Saidi, Y; Harrison, L; Turkova, A; Tudor-Williams, G; Tudor-Williams, G Hepatic, Renal, Hematologic, and Inflammatory Markers in HIV-Infected Children on Long-term Suppressive Antiretroviral Therapy.
J Pediatric Infect Dis Soc. 2017; 6(3):e109-e115-e109-e115 [OPEN ACCESS]
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Schweiger, M; Romauch, M; Schreiber, R; Grabner, GF; Hütter, S; Kotzbeck, P; Benedikt, P; Eichmann, TO; Yamada, S; Knittelfelder, O; Diwoky, C; Doler, C; Mayer, N; De Cecco, W; Breinbauer, R; Zimmermann, R; Zechner, R Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Nat Commun. 2017; 8(5):14859-14859 [OPEN ACCESS]
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2016

Tang, Y; Fickert, P; Trauner, M; Marcus, N; Blomenkamp, K; Teckman, J Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.
Am J Physiol Gastrointest Liver Physiol. 2016; 311(1):G156-G165 [OPEN ACCESS]
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2015

Weinert, BT; Moustafa, T; Iesmantavicius, V; Zechner, R; Choudhary, C Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions.
EMBO J. 2015; 34(21):2620-2632 [OPEN ACCESS]
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2014

Fuchs, CD; Claudel, T; Trauner, M Role of metabolic lipases and lipolytic metabolites in the pathogenesis of NAFLD.
Trends Endocrinol Metab. 2014; 25(11):576-585
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Lunova, M; Goehring, C; Kuscuoglu, D; Mueller, K; Chen, Y; Walther, P; Deschemin, JC; Vaulont, S; Haybaeck, J; Lackner, C; Trautwein, C; Strnad, P Hepcidin knockout mice fed with iron-rich diet develop chronic liver injury and liver fibrosis due to lysosomal iron overload.
J Hepatol. 2014; 61(3):633-641
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2013

Thomas, G; Betters, JL; Lord, CC; Brown, AL; Marshall, S; Ferguson, D; Sawyer, J; Davis, MA; Melchior, JT; Blume, LC; Howlett, AC; Ivanova, PT; Milne, SB; Myers, DS; Mrak, I; Leber, V; Heier, C; Taschler, U; Blankman, JL; Cravatt, BF; Lee, RG; Crooke, RM; Graham, MJ; Zimmermann, R; Brown, HA; Brown, JM The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome.
Cell Rep. 2013; 5(2):508-520 [OPEN ACCESS]
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2012

Li, SY; Yang, Z; Gao, YF; Li, GY; Wang, HP; Hinghofer-Szalkay, HG; Ligustrazine and the Contractile Properties of Soleus Muscle in Hindlimb-Unloaded Rats.
Aviat Space Environ Med. 2012; 83(11):1049-1054
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Quiroga, AD; Li, L; Trötzmüller, M; Nelson, R; Proctor, SD; Köfeler, H; Lehner, R Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia.
Hepatology. 2012; 56(6):2188-2198 [OPEN ACCESS]
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Silbernagel, G; Kovarova, M; Cegan, A; Machann, J; Schick, F; Lehmann, R; Häring, HU; Stefan, N; Schleicher, E; Fritsche, A; Peter, A High hepatic SCD1 activity is associated with low liver fat content in healthy subjects under a lipogenic diet.
J Clin Endocrinol Metab. 2012; 97(12):E2288-E2292
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2011

Ilic, S; Drmic, D; Zarkovic, K; Kolenc, D; Brcic, L; Radic, B; Djuzel, V; Blagaic, AB; Romic, Z; Dzidic, S; Kalogjera, L; Seiwerth, S; Sikiric, P Ibuprofen hepatic encephalopathy, hepatomegaly, gastric lesion and gastric pentadecapeptide BPC 157 in rats.
Eur J Pharmacol. 2011; 667(1-3): 322-329.
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Riegler, B; Besenboeck, C; Bauer, R; Nimpf, J; Schneider, WJ Enzymes involved in hepatic acylglycerol metabolism in the chicken.
Biochem Biophys Res Commun. 2011; 406(2): 257-261.
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Tannapfel, A; Denk, H; Dienes, HP; Langner, C; Schirmacher, P; Trauner, M; Flott-Rahmel, B Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease.
Virchows Arch. 2011; 458(5): 511-523.
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2010

Frohlich, E; Kueznik, T; Samberger, C; Roblegg, E; Wrighton, C; Pieber, TR Size-dependent effects of nanoparticles on the activity of cytochrome P450 isoenzymes.
TOXICOL APPL PHARMACOL. 2010; 242(3): 326-332.
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Radner, FP; Streith, IE; Schoiswohl, G; Schweiger, M; Kumari, M; Eichmann, TO; Rechberger, G; Koefeler, HC; Eder, S; Schauer, S; Theussl, HC; Preiss-Landl, K; Lass, A; Zimmermann, R; Hoefler, G; Zechner, R; Haemmerle, G Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).
J Biol Chem. 2010; 285(10):7300-7311 [OPEN ACCESS]
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Trottier, J; El Husseini, D; Perreault, M; Pâquet, S; Caron, P; Bourassa, S; Verreault, M; Inaba, TT; Poirier, GG; Bélanger, A; Guillemette, C; Trauner, M; Barbier, O The human UGT1A3 enzyme conjugates norursodeoxycholic acid into a C23-ester glucuronide in the liver.
J Biol Chem. 2010; 285(2):1113-1121 [OPEN ACCESS]
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2009

Fickert, P; Fuchsbichler, A; Wagner, M; Silbert, D; Zatloukal, K; Denk, H; Trauner, M The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.
Hepatology. 2009; 50(3):893-899 [OPEN ACCESS]
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Liang, R; Nickkholgh, A; Hoffmann, K; Kern, M; Schneider, H; Sobirey, M; Zorn, M; Büchler, MW; Schemmer, P Melatonin protects from hepatic reperfusion injury through inhibition of IKK and JNK pathways and modification of cell proliferation.
J Pineal Res. 2009; 46(1):8-14
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Rensen, SS; Slaats, Y; Nijhuis, J; Jans, A; Bieghs, V; Driessen, A; Malle, E; Greve, JW; Buurman, WA Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis.
Am J Pathol. 2009; 175(4): 1473-1482. [OPEN ACCESS]
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Schreiber, R; Taschler, U; Wolinski, H; Seper, A; Tamegger, SN; Graf, M; Kohlwein, SD; Haemmerle, G; Zimmermann, R; Zechner, R; Lass, A Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver.
J Lipid Res. 2009; 50(12):2514-2523 [OPEN ACCESS]
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2008

Hermann, M; Kietzmann, MU; Ivancic, M; Zenzmaier, C; Luiten, RGM; Skranc, W; Wubbolts, M; Winkler, M; Birner-Gruenberger, R; Pichler, H; Schwab, H Alternative pig liver esterase (APLE) - cloning, identification and functional expression in Pichia pastoris of a versatile new biocatalyst.
J BIOTECHNOL. 2008; 133(3): 301-310.
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2007

Stauber, RE; Lackner, C Noninvasive diagnosis of hepatic fibrosis in chronic hepatitis C.
World J Gastroenterol. 2007; 13(32): 4287-4294. [OPEN ACCESS]
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Zollner, G; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis.
Liver Int. 2007; 27(7):920-929
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2006

Eller, P; Hochegger, K; Wehinger, A; Tancevski, I; Schgoer, W; Ritsch, A; Patsch, JR Hepatic ENPP1 expression is induced in diabetic rabbits.
Mamm Genome. 2006; 17(8):886-891
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Gurakuqi, GC; Stadlbauer, V; Stepan, V; Warnkross, H; Trauner, M Addison's disease as a rare cause of chronically elevated liver enzymes].
Z Gastroenterol. 2006; 44(2):179-183 (- Case Report)
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Hofmann, G; Bauernhofer, T; Krippl, P; Lang-Loidolt, D; Horn, S; Goessler, W; Schippinger, W; Ploner, F; Stoeger, H; Samonigg, H Plasmapheresis reverses all side-effects of a cisplatin overdose--a case report and treatment recommendation.
BMC Cancer. 2006; 6(2):1-1 (- Case Report) [OPEN ACCESS]
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Trop, M Silver-coated dressing acticoat caused raised liver enzymes and argyria-like symptoms in burn patient.
J TRAUMA. 2006; 61(4): 1024-1024.
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2005

Eller, P; Schgoer, W; Mueller, T; Tancevski, I; Wehinger, A; Ulmer, H; Foeger, B; Haltmayer, M; Ritsch, A; Patsch, JR Hepatic lipase polymorphism and increased risk of peripheral arterial disease.
J Intern Med. 2005; 258(4):344-348 [OPEN ACCESS]
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Kratky, D; Zimmermann, R; Wagner, EM; Strauss, JG; Jin, W; Kostner, GM; Haemmerle, G; Rader, DJ; Zechner, R Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue.
J CLIN INVEST. 2005; 115(1): 161-167. [OPEN ACCESS]
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2004

Bartels, M; Biesalski, HK; Engelhart, K; Sendlhofer, G; Rehak, P; Nagel, E Pilot study on the effect of parenteral vitamin E on ischemia and reperfusion induced liver injury: a double blind, randomized, placebo-controlled trial.
Clin Nutr. 2004; 23(6):1360-1370
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Hartwig, D; Schoeneich, L; Greeve, J; Schütte, C; Dorn, I; Kirchner, H; Hennig, H Interferon-alpha stimulation of liver cells enhances hepatitis delta virus RNA editing in early infection.
J Hepatol. 2004; 41(4): 667-672.
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Veres, B; Radnai, B; Gallyas, F; Varbiro, G; Berente, Z; Osz, E; Sumegi, B Regulation of kinase cascades and transcription factors by a poly(ADP-ribose) polymerase-1 inhibitor, 4-hydroxyquinazoline, in lipopolysaccharide-induced inflammation in mice.
J Pharmacol Exp Ther. 2004; 310(1): 247-255.
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2002

Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H Bile acid-induced Mallory body formation in drug-primed mouse liver.
Am J Pathol. 2002; 161(6):2019-2026 [OPEN ACCESS]
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Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H Cytokeratins as targets for bile acid-induced toxicity.
Am J Pathol. 2002; 160(2):491-499 [OPEN ACCESS]
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2001

Frank, S; Hrzenjak, A; Blaschitz, A; Dohr, G; Kostner, GM Role of various tissues in apo(a) fragmentation and excretion of fragments by the kidney.
Eur J Clin Invest. 2001; 31(6):504-512
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2000

Nöhammer, C; El-Shabrawi, Y; Schauer, S; Hiden, M; Berger, J; Forss-Petter, S; Winter, E; Eferl, R; Zechner, R; Hoefler, G cDNA cloning and analysis of tissue-specific expression of mouse peroxisomal straight-chain acyl-CoA oxidase.
EUR J BIOCHEM 2000 267: 1254-1260. [OPEN ACCESS]
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Schimpl, G; Pesendorfer, P; Kuesz, AM; Ratschek, M; Höllwarth, ME The impact of hepatic xanthine oxidase and xanthine dehydrogenase activities on liver function in chronic cholestasis.
PEDIAT SURG INT 2000 16: 297-301.
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1999

Bradham, CA; Schemmer, P; Stachlewitz, RF; Thurman, RG; Brenner, DA Activation of nuclear factor-kappaB during orthotopic liver transplantation in rats is protective and does not require Kupffer cells.
Liver Transpl Surg. 1999; 5(4):282-293
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Enomoto, N; Yamashina, S; Goto, M; Schemmer, P; Thurman, RG Desensitization to LPS after ethanol involves the effect of endotoxin on voltage-dependent calcium channels.
Am J Physiol. 1999; 277(6 Pt 1):G1251-G1258
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1998

Cerwenka, H; Bacher, H; Werkgartner, G; El-Shabrawi, A; Quehenberger, F; Hauser, H; Mischinger, HJ Antioxidant treatment during liver resection for alleviation of ischemia-reperfusion injury.
Hepatogastroenterology. 1998; 45(21):777-782
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Khoschsorur, G; Auer, T; Lanzer, G; Petritsch, P; Holzer, H; Tscheliessnigg, KH The determination of metabolite M17 and its meaning for immunosuppressive cyclosporin therapy.
Angiology. 1998; 49(4):307-314
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Merkel, M; Weinstock, PH; Chajek-Shaul, T; Radner, H; Yin, B; Breslow, JL; Goldberg, IJ Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia.
J Clin Invest. 1998; 102(5):893-901 [OPEN ACCESS]
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Plecko, B; Erwa, W; Wermuth, B Partial N-acetylglutamate synthetase deficiency in a 13-year-old girl: diagnosis and response to treatment with N-carbamylglutamate.
Eur J Pediatr. 1998; 157(12):996-998 (- Case Report)
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1997

Meiner, V; Tam, C; Gunn, MD; Dong, LM; Weisgraber, KH; Novak, S; Myers, HM; Erickson, SK; Farese, RV Tissue expression studies on the mouse acyl-CoA: cholesterol acyltransferase gene (Acact): findings supporting the existence of multiple cholesterol esterification enzymes in mice.
J Lipid Res. 1997; 38(9): 1928-1933. [OPEN ACCESS]
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Schön, MR; Akkoc, N; Schrem, H; Keech, G; Kräutlein, K; Lemmens, HP; Wolf, S; Tominaga, M; Kollmar, O; Neuhaus, P alpha-Glutathione-S-transferase is a sensitive marker of hepatocellular damage due to warm or cold ischemia in pig liver transplantation.
Transplant Proc. 1997; 29(7):3036-3038
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1996

Caira, F; Cherkaoui-Malki, M; Hoefler, G; Latruffe, N Cloning and tissue expression of two cDNAs encoding the peroxisomal 2-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in the guinea pig liver.
FEBS Lett. 1996; 378(1):57-60 [OPEN ACCESS]
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Duque, M; Graupner, M; Stütz, H; Wicher, I; Zechner, R; Paltauf, F; Hermetter, A New fluorogenic triacylglycerol analogs as substrates for the determination and chiral discrimination of lipase activities.
J Lipid Res. 1996; 37(4):868-876 [OPEN ACCESS]
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1995

Rau, HG; Schardey, HM; Buttler, E; Reuter, C; Cohnert, TU; Schildberg, FW A comparison of different techniques for liver resection: blunt dissection, ultrasonic aspirator and jet-cutter.
Eur J Surg Oncol. 1995; 21(2):183-187
PubMed

 

Scharnagl, H; März, W; Schliack, M; Löser, R; Gross, W A novel assay for cytosolic 3-hydroxy-3-methylglutaryl-coenzyme A synthase activity using reversed-phase ion-pair chromatography: demonstration that Lifibrol (K12.148) modulates the enzyme activity.
J LIPID RES 1995 36: 622-627. [OPEN ACCESS]
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1994

Hendrickx, J; Coucke, P; Hors-Cayla, MC; Smit, GP; Shin, YS; Deutsch, J; Smeitink, J; Berger, R; Lee, P; Fernandes, J Localization of a new type of X-linked liver glycogenosis to the chromosomal region Xp22 containing the liver alpha-subunit of phosphorylase kinase (PHKA2).
GENOMICS. 1994; 21(3): 620-625. (- Case Report)
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