Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: LIQUID BIOPSY, . Treffer: 40

2023

Hoenigl, M; Egger, M; Price, J; Krause, R; Prattes, J; White, PL Metagenomic Next-Generation Sequencing of Plasma for Diagnosis of COVID-19-Associated Pulmonary Aspergillosis.
J Clin Microbiol. 2023; 61(3):e0185922 Doi: 10.1128/jcm.01859-22 [OPEN ACCESS]
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Rassner, M; Waldeck, S; Follo, M; Jilg, S; Philipp, U; Jolic, M; Wehrle, J; Jost, PJ; Peschel, C; Illert, AL; Duyster, J; Scherer, F; von, Bubnoff, N Development of Highly Sensitive Digital Droplet PCR for Detection of cKIT Mutations in Circulating Free DNA That Mediate Resistance to TKI Treatment for Gastrointestinal Stromal Tumor (GIST).
Int J Mol Sci. 2023; 24(6): Doi: 10.3390/ijms24065411 [OPEN ACCESS]
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2022

Donker, HC; Schuuring, E; Heitzer, E; Groen, HJM Decoding circulating tumor DNA to identify durable benefit from immunotherapy in lung cancer
LUNG CANCER. 2022; 170: 52-57. Doi: 10.1016/j.lungcan.2022.05.013
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Eisenhardt, AE; Brugger, Z; Lausch, U; Kiefer, J; Zeller, J; Runkel, A; Schmid, A; Bronsert, P; Wehrle, J; Leithner, A; Liegl-Atzwanger, B; Giunta, RE; Eisenhardt, SU; Braig, D Genotyping of Circulating Free DNA Enables Monitoring of Tumor Dynamics in Synovial Sarcomas.
Cancers (Basel). 2022; 14(9): 2078 Doi: 10.3390/cancers14092078 [OPEN ACCESS]
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Eisenhardt, AE; Schmid, A; Esser, J; Brugger, Z; Lausch, U; Kiefer, J; Braig, M; Runkel, A; Wehrle, J; Claus, R; Bronsert, P; Leithner, A; Liegl-Atzwanger, B; Zeller, J; Papini, R; von, Laffert, M; Pfitzner, BM; Koulaxouzidis, G; Giunta, RE; Eisenhardt, SU; Braig, D Targeted next-generation sequencing of circulating free DNA enables non-invasive tumor detection in myxoid liposarcomas.
Mol Cancer. 2022; 21(1): 50 Doi: 10.1186/s12943-022-01523-x [OPEN ACCESS]
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Hallermayr, A; Wohlfrom, T; Steinke-Lange, V; Benet-Pages, A; Scharf, F; Heitzer, E; Mansmann, U; Haberl, C; de Wit, M; Vogelsang, H; Rentsch, M; Holinski-Feder, E; Pickl, JMA Somatic copy number alteration and fragmentation analysis in circulating tumor DNA for cancer screening and treatment monitoring in colorectal cancer patients
J HEMATOL ONCOL. 2022; 15(1): 125 Doi: 10.1186/s13045-022-01342-z [OPEN ACCESS]
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Hasenleithner, SO; Speicher, MR A clinician's handbook for using ctDNA throughout the patient journey.
Mol Cancer. 2022; 21(1): 81 Doi: 10.1186/s12943-022-01551-7 [OPEN ACCESS]
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Horgan, D; Cufer, T; Gatto, F; Lugowska, I; Verbanac, D; Carvalho, A; Lal, JA; Kozaric, M; Toomey, S; Ivanov, HY; Longshore, J; Malapelle, U; Hasenleithner, S; Hofman, P; Alix-Panabieres, C Accelerating the Development and Validation of Liquid Biopsy for Early Cancer Screening and Treatment Tailoring
HEALTHCARE-BASEL. 2022; 10(9): 1714 Doi: 10.3390/healthcare10091714 [OPEN ACCESS]
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Suppan, C; Graf, R; Jahn, S; Zhou, Q; Klocker, EV; Bartsch, R; Terbuch, A; Kashofer, K; Regitnig, P; Lindenmann, J; Posch, F; Gerritsmann, H; Jost, PJ; Heitzer, E; Dandachi, N; Balic, M Sensitive and robust liquid biopsy-based detection of PIK3CA mutations in hormone-receptor-positive metastatic breast cancer patients.
Br J Cancer. 2022; 126(3):456-463 Doi: 10.1038/s41416-021-01601-9 [OPEN ACCESS]
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Theel, EK; Schwaminger, SP Microfluidic Approaches for Affinity-Based Exosome Separation.
Int J Mol Sci. 2022; 23(16): Doi: 10.3390/ijms23169004 [OPEN ACCESS]
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Trapp, EK; Fasching, PA; Fehm, T; Schneeweiss, A; Mueller, V; Harbeck, N; Lorenz, R; Schumacher, C; Heinrich, G; Schochter, F; de Gregorio, A; Tzschaschel, M; Rack, B; Janni, W; Friedl, TWP Does the Presence of Circulating Tumor Cells in High-Risk Early Breast Cancer Patients Predict the Site of First Metastasis-Results from the Adjuvant SUCCESS A Trial
CANCERS. 2022; 14(16): 3949 Doi: 10.3390/cancers14163949 [OPEN ACCESS]
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2021

Krappinger, JC; Bonstingl, L; Pansy, K; Sallinger, K; Wreglesworth, NI; Grinninger, L; Deutsch, A; El-Heliebi, A; Kroneis, T; Mcfarlane, RJ; Sensen, CW; Feichtinger, J Non-coding Natural Antisense Transcripts: Analysis and Application.
J Biotechnol. 2021; 340:75-101 Doi: 10.1016/j.jbiotec.2021.08.005
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Laprovitera, N; Riefolo, M; Ambrosini, E; Klec, C; Pichler, M; Ferracin, M Cancer of Unknown Primary: Challenges and Progress in Clinical Management.
Cancers (Basel). 2021; 13(3): Doi: 10.3390/cancers13030451 [OPEN ACCESS]
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Smolle, E; Taucher, V; Lindenmann, J; Pichler, M; Smolle-Juettner, FM Liquid biopsy in non-small cell lung cancer-current status and future outlook-a narrative review.
Transl Lung Cancer Res. 2021; 10(5): 2237-2251. Doi: 10.21037/tlcr-21-3 [OPEN ACCESS]
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Stitz, R; Buder, A; Silye, R; Baumgartner, B; Pühringer, F; Filipits, M; Oberndorfer, E; Heitzer, E Validation of a next-generation sequencing assay for the detection of EGFR mutations in cell-free circulating tumor DNA.
EXP MOL PATHOL. 2021; 123: 104685 Doi: 10.1016/j.yexmp.2021.104685
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2020

Barth, DA; Drula, R; Ott, L; Fabris, L; Slaby, O; Calin, GA; Pichler, M Circulating Non-coding RNAs in Renal Cell Carcinoma-Pathogenesis and Potential Implications as Clinical Biomarkers.
Front Cell Dev Biol. 2020; 8:828 Doi: 10.3389/fcell.2020.00828 [OPEN ACCESS]
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Bourrier, C; Pierga, JY; Xuereb, L; Salaun, H; Proudhon, C; Speicher, MR; Belic, J; Heitzer, E; Lockhart, BP; Guigal-Stephan, N Shallow Whole-Genome Sequencing from Plasma Identifies FGFR1 Amplified Breast Cancers and Predicts Overall Survival.
Cancers (Basel). 2020; 12(6): Doi: 10.3390/cancers12061481 [OPEN ACCESS]
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Gerber, T; Taschner-Mandl, S; Saloberger-Sindhöringer, L; Popitsch, N; Heitzer, E; Witt, V; Geyeregger, R; Hutter, C; Schwentner, R; Ambros, IM; Ambros, PF Assessment of Pre-Analytical Sample Handling Conditions for Comprehensive Liquid Biopsy Analysis.
J Mol Diagn. 2020; 22(8):1070-1086 Doi: 10.1016/j.jmoldx.2020.05.006 [OPEN ACCESS]
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Hofmann, L; Sallinger, K; Haudum, C; Smolle, M; Heitzer, E; Moser, T; Novy, M; Gesson, K; Kroneis, T; Bauernhofer, T; El-Heliebi, A A Multi-Analyte Approach for Improved Sensitivity of Liquid Biopsies in Prostate Cancer.
Cancers (Basel). 2020; 12(8): Doi: 10.3390/cancers12082247 [OPEN ACCESS]
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Koch, C; Kuske, A; Joosse, SA; Yigit, G; Sflomos, G; Thaler, S; Smit, DJ; Werner, S; Borgmann, K; Gärtner, S; Mossahebi Mohammadi, P; Battista, L; Cayrefourcq, L; Altmüller, J; Salinas-Riester, G; Raithatha, K; Zibat, A; Goy, Y; Ott, L; Bartkowiak, K; Tan, TZ; Zhou, Q; Speicher, MR; Müller, V; Gorges, TM; Jücker, M; Thiery, JP; Brisken, C; Riethdorf, S; Alix-Panabières, C; Pantel, K Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity.
EMBO Mol Med. 2020; 12(9):e11908-e11908 Doi: 10.15252/emmm.201911908 [OPEN ACCESS]
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Weber, S; Spiegl, B; Perakis, SO; Ulz, CM; Abuja, PM; Kashofer, K; Leest, PV; Azpurua, MA; Tamminga, M; Brudzewsky, D; Rothwell, DG; Mohan, S; Sartori, A; Lampignano, R; Konigshofer, Y; Sprenger-Haussels, M; Wikman, H; Bergheim, IR; Kloten, V; Schuuring, E; Speicher, MR; Heitzer, E Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling.
Cancers (Basel). 2020; 12(6): 1588 Doi: 10.3390/cancers12061588 [OPEN ACCESS]
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2019

de Wit, S; Rossi, E; Weber, S; Tamminga, M; Manicone, M; Swennenhuis, JF; Groothuis-Oudshoorn, CGM; Vidotto, R; Facchinetti, A; Zeune, LL; Schuuring, E; Zamarchi, R; Hiltermann, TJN; Speicher, MR; Heitzer, E; Terstappen, LWMM; Groen, HJM Single tube liquid biopsy for advanced non-small cell lung cancer.
Int J Cancer. 2019; 144(12): 3127-3137. Doi: 10.1002/ijc.32056 [OPEN ACCESS]
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Jilg, S; Rassner, M; Maier, J; Waldeck, S; Kehl, V; Follo, M; Philipp, U; Sauter, A; Specht, K; Mitschke, J; Lange, T; Bauer, S; Jost, PJ; Peschel, C; Duyster, J; Gaiser, T; Hohenberger, P; von Bubnoff, N Circulating cKIT and PDGFRA DNA indicates disease activity in Gastrointestinal Stromal Tumor (GIST).
Int J Cancer. 2019; 145(8):2292-2303 Doi: 10.1002/ijc.32282
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Marcuello, M; Vymetalkova, V; Neves, RPL; Duran-Sanchon, S; Vedeld, HM; Tham, E; van Dalum, G; Flügen, G; Garcia-Barberan, V; Fijneman, RJ; Castells, A; Vodicka, P; Lind, GE; Stoecklein, NH; Heitzer, E; Gironella, M Circulating biomarkers for early detection and clinical management of colorectal cancer.
MOL ASPECTS MED. 2019; 69(9): 107-122. Doi: 10.1016/j.mam.2019.06.002 [OPEN ACCESS]
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2018

Buder, A; Hochmair, MJ; Schwab, S; Bundalo, T; Schenk, P; Errhalt, P; Mikes, RE; Absenger, G; Patocka, K; Baumgartner, B; Setinek, U; Burghuber, OC; Prosch, H; Pirker, R; Filipits, M Cell-Free Plasma DNA-Guided Treatment With Osimertinib in Patients With Advanced EGFR-Mutated NSCLC.
J Thorac Oncol. 2018; 13(6):821-830 Doi: 10.1016/j.jtho.2018.02.014 [OPEN ACCESS]
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Markou, A; Lazaridou, M; Paraskevopoulos, P; Chen, S; Świerczewska, M; Budna, J; Kuske, A; Gorges, TM; Joosse, SA; Kroneis, T; Zabel, M; Sedlmayr, P; Alix-Panabières, C; Pantel, K; Lianidou, ES Multiplex Gene Expression Profiling of In Vivo Isolated Circulating Tumor Cells in High-Risk Prostate Cancer Patients.
Clin Chem. 2018; 64(2):297-306 Doi: 10.1373/clinchem.2017.275503 [OPEN ACCESS]
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2017

Hochmair, M; Holzer, S; Filipits, M; Mohn-Staudner, A; Errhalt, P; Absenger, G; Bundalo, T; Arns, M; Setinek, U; Mikes, R; Kolb, R; Schumacher, M; Zochbauer-Muller, S; Patocka, K; Haslbauer, F; Rudzki, J; Burghuber, O EGFR T790M Resistance Mutation in NSCLC: Real-Life Data of Austrian Patients Treated with Osimertinib
J THORAC ONCOL. .. 2017; 12(1):S1254-S1254. Doi: 10.1016/j.jtho.2016.11.1769 [Poster]
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Nadal, C; Winder, T; Gerger, A; Tougeron, D Future perspectives of circulating tumor DNA in colorectal cancer.
Tumour Biol. 2017; 39(5):1010428317705749-1010428317705749 Doi: 10.1177/1010428317705749 [OPEN ACCESS]
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Perakis, S; Auer, M; Belic, J; Heitzer, E Advances in Circulating Tumor DNA Analysis.
Adv Clin Chem. 2017; 80(10):73-153 Doi: 10.1016/bs.acc.2016.11.005
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Perakis, S; Speicher, MR Emerging concepts in liquid biopsies.
BMC Med. 2017; 15(1):75-75 Doi: 10.1186/s12916-017-0840-6 [OPEN ACCESS]
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Ulz, P; Heitzer, E; Geigl, JB; Speicher, MR Patient monitoring through liquid biopsies using circulating tumor DNA.
Int J Cancer. 2017; 141(5):887-896 Doi: 10.1002/ijc.30759 [OPEN ACCESS]
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2016

Belic, J; Koch, M; Ulz, P; Auer, M; Gerhalter, T; Mohan, S; Fischereder, K; Petru, E; Bauernhofer, T; Geigl, JB; Speicher, MR; Heitzer, E mFast-SeqS as a Monitoring and Pre-screening Tool for Tumor-Specific Aneuploidy in Plasma DNA.
Adv Exp Med Biol. 2016; 924:147-155 Doi: 10.1007/978-3-319-42044-8_28
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Heitzer, E; Ulz, P; Geigl, JB; Speicher, MR Non-invasive detection of genome-wide somatic copy number alterations by liquid biopsies.
Mol Oncol. 2016; 10(3):494-502 Doi: 10.1016/j.molonc.2015.12.004 [OPEN ACCESS]
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Hofman, P; Popper, HH Pathologists and liquid biopsies: to be or not to be?
Virchows Arch. 2016; 469(6):601-609 Doi: 10.1007/s00428-016-2004-z
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Ignatiadis, M; Rack, B; Rothé, F; Riethdorf, S; Decraene, C; Bonnefoi, H; Dittrich, C; Messina, C; Beauvois, M; Trapp, E; Goulioti, T; Tryfonidis, K; Pantel, K; Repollet, M; Janni, W; Piccart, M; Sotiriou, C; Litiere, S; Pierga, JY Liquid biopsy-based clinical research in early breast cancer: The EORTC 90091-10093 Treat CTC trial.
Eur J Cancer. 2016; 63(10):97-104 Doi: 10.1016/j.ejca.2016.04.024
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Schneider, D; Riegman, PH; Cronin, M; Negrouk, A; Moch, H; Balling, R; Penault-Llorca, F; Zatloukal, K; Horgan, D Accelerating the Development and Validation of New Value-Based Diagnostics by Leveraging Biobanks.
Public Health Genomics. 2016; 19(3):160-169 Doi: 10.1159/000446534 [OPEN ACCESS]
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2015

Heitzer, E; Ulz, P; Geigl, JB Circulating tumor DNA as a liquid biopsy for cancer.
Clin Chem. 2015; 61(1):112-123 Doi: 10.1373/clinchem.2014.222679 [OPEN ACCESS]
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2013

Heitzer, E; Auer, M; Gasch, C; Pichler, M; Ulz, P; Hoffmann, EM; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Lackner, C; Höfler, G; Eisner, F; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing.
Cancer Res. 2013; 73(10):2965-2975 Doi: 10.1158/0008-5472.CAN-12-4140 [OPEN ACCESS]
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Heitzer, E; Ulz, P; Belic, J; Gutschi, S; Quehenberger, F; Fischereder, K; Benezeder, T; Auer, M; Pischler, C; Mannweiler, S; Pichler, M; Eisner, F; Haeusler, M; Riethdorf, S; Pantel, K; Samonigg, H; Hoefler, G; Augustin, H; Geigl, JB; Speicher, MR Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing.
Genome Med. 2013; 5(4):30-30 Doi: 10.1186/gm434 [OPEN ACCESS]
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2012

Rink, M; Chun, FK; Dahlem, R; Soave, A; Minner, S; Hansen, J; Stoupiec, M; Coith, C; Kluth, LA; Ahyai, SA; Friedrich, MG; Shariat, SF; Fisch, M; Pantel, K; Riethdorf, S Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective study.
Eur Urol. 2012; 61(4):810-7 Doi: 10.1016/j.eururo.2012.01.017
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