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Publikationen

Suchbegriffe: ION CHANNELS - GENETICS , . Treffer: 33

2019

Bandleon, S; Strunz, PP; Pickel, S; Tiapko, O; Cellini, A; Miranda-Laferte, E; Eder-Negrin, P FKBP52 regulates TRPC3-dependent Ca²⁺ signals and the hypertrophic growth of cardiomyocyte cultures.
J Cell Sci. 2019; 132(20): Doi: 10.1242/jcs.231506 [OPEN ACCESS]
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2016

Kirschmer, N; Bandleon, S; von Ehrlich-Treuenstätt, V; Hartmann, S; Schaaf, A; Lamprecht, AK; Miranda-Laferte, E; Langsenlehner, T; Ritter, O; Eder, P TRPC4α and TRPC4β Similarly Affect Neonatal Cardiomyocyte Survival during Chronic GPCR Stimulation.
PLoS One. 2016; 11(12):e0168446-e0168446 Doi: 10.1371/journal.pone.0168446 [OPEN ACCESS]
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Tiapko, O; Bacsa, B; de la Cruz, GG; Glasnov, T; Groschner, K Optopharmacological control of TRPC channels by coumarin-caged lipids is associated with a phototoxic membrane effect.
Sci China Life Sci. 2016; 59(8):802-810 Doi: 10.1007/s11427-016-5095-5 [OPEN ACCESS]
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2015

Bondarenko, AI; Parichatikanond, W; Madreiter, CT; Rost, R; Waldeck-Weiermair, M; Malli, R; Graier, WF UCP2 modulates single-channel properties of a MCU-dependent Ca(2+) inward current in mitochondria.
Pflugers Arch. 2015; 467(12):2509-2518 Doi: 10.1007/s00424-015-1727-z [OPEN ACCESS]
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Doleschal, B; Primessnig, U; Wölkart, G; Wolf, S; Schernthaner, M; Lichtenegger, M; Glasnov, TN; Kappe, CO; Mayer, B; Antoons, G; Heinzel, F; Poteser, M; Groschner, K TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.
Cardiovasc Res. 2015; 106(1):163-173 Doi: 10.1093/cvr/cvv022 [OPEN ACCESS]
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Li, C; Rezania, S; Kammerer, S; Sokolowski, A; Devaney, T; Gorischek, A; Jahn, S; Hackl, H; Groschner, K; Windpassinger, C; Malle, E; Bauernhofer, T; Schreibmayer, W Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line.
Sci Rep. 2015; 5(2):8364-8364 Doi: 10.1038/srep08364 [OPEN ACCESS]
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Rockstroh, D; Landgraf, K; Wagner, IV; Gesing, J; Tauscher, R; Lakowa, N; Kiess, W; Bühligen, U; Wojan, M; Till, H; Blüher, M; Körner, A Direct evidence of brown adipocytes in different fat depots in children.
PLoS One. 2015; 10(2):e0117841-e0117841 Doi: 10.1371/journal.pone.0117841 [OPEN ACCESS]
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2014

Alkhani, H; Ase, AR; Grant, R; O'Donnell, D; Groschner, K; Séguéla, P Contribution of TRPC3 to store-operated calcium entry and inflammatory transductions in primary nociceptors.
Mol Pain. 2014; 10(6):43-43 Doi: 10.1186/1744-8069-10-43 [OPEN ACCESS]
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Lichtenegger, M; Groschner, K TRPC3: a multifunctional signaling molecule.
Handb Exp Pharmacol. 2014; 222: 67-84. Doi: 10.1007/978-3-642-54215-2_4
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Olschewski, A; Papp, R; Nagaraj, C; Olschewski, H Ion channels and transporters as therapeutic targets in the pulmonary circulation.
Pharmacol Ther. 2014; 144(3):349-368 Doi: 10.1016/j.pharmthera.2014.08.001
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Seo, K; Rainer, PP; Shalkey Hahn, V; Lee, DI; Jo, SH; Andersen, A; Liu, T; Xu, X; Willette, RN; Lepore, JJ; Marino, JP; Birnbaumer, L; Schnackenberg, CG; Kass, DA Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.
Proc Natl Acad Sci U S A. 2014; 111(4):1551-1556 Doi: 10.1073/pnas.1308963111 [OPEN ACCESS]
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2013

Waldeck-Weiermair, M; Deak, AT; Groschner, LN; Alam, MR; Jean-Quartier, C; Malli, R; Graier, WF Molecularly distinct routes of mitochondrial Ca2+ uptake are activated depending on the activity of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA).
J Biol Chem. 2013; 288(21):15367-15379 Doi: 10.1074/jbc.M113.462259 [OPEN ACCESS]
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2012

Donnerer, J; Liebmann, I Thermal stimulation of primary sensory neurons in the rat hind paw: effect of morphine on ERK1/2 phosphorylation, TRPV1 and TRPA1 channel expression.
Pharmacology. 2012; 90(5-6):298-306 Doi: 10.1159/000343133
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Fiorillo, C; Moro, F; Brisca, G; Astrea, G; Nesti, C; Balint, Z; Olschewski, A; Meschini, MC; Guelly, C; Auer-Grumbach, M; Battini, R; Pedemonte, M; Romano, A; Menchise, V; Biancheri, R; Santorelli, FM; Bruno, C TRPV4 mutations in children with congenital distal spinal muscular atrophy.
Neurogenetics. 2012; 13(3):195-203 Doi: 10.1007/s10048-012-0328-7 (- Case Report)
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Schindl, R; Fritsch, R; Jardin, I; Frischauf, I; Kahr, H; Muik, M; Riedl, MC; Groschner, K; Romanin, C Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.
J Biol Chem. 2012; 287(42):35612-35620 Doi: 10.1074/jbc.M112.400952 [OPEN ACCESS]
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2011

Waldeck-Weiermair, M; Jean-Quartier, C; Rost, R; Khan, MJ; Vishnu, N; Bondarenko, AI; Imamura, H; Malli, R; Graier, WF Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca2+ Uptake Pathways.
J Biol Chem. 2011; 286(32):28444-28455 Doi: 10.1074/jbc.M111.244517 [OPEN ACCESS]
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2010

Auer-Grumbach, M; Olschewski, A; Papić, L; Kremer, H; McEntagart, ME; Uhrig, S; Fischer, C; Fröhlich, E; Bálint, Z; Tang, B; Strohmaier, H; Lochmüller, H; Schlotter-Weigel, B; Senderek, J; Krebs, A; Dick, KJ; Petty, R; Longman, C; Anderson, NE; Padberg, GW; Schelhaas, HJ; van Ravenswaaij-Arts, CM; Pieber, TR; Crosby, AH; Guelly, C Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C.
Nat Genet. 2010; 42(2):160-164 Doi: 10.1038/ng.508 [OPEN ACCESS]
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Graziani, A; Poteser, M; Heupel, WM; Schleifer, H; Krenn, M; Drenckhahn, D; Romanin, C; Baumgartner, W; Groschner, K Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction.
J Biol Chem. 2010; 285(6):4213-4223 Doi: 10.1074/jbc.M109.060301 [OPEN ACCESS]
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Waldeck-Weiermair, M; Duan, X; Naghdi, S; Khan, MJ; Trenker, M; Malli, R; Graier, WF Uncoupling protein 3 adjusts mitochondrial Ca(2+) uptake to high and low Ca(2+) signals.
Cell Calcium. 2010; 48(5): 288-301. Doi: 10.1016/j.ceca.2010.10.004 [OPEN ACCESS]
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Waldeck-Weiermair, M; Malli, R; Naghdi, S; Trenker, M; Kahn, MJ; Graier, WF The contribution of UCP2 and UCP3 to mitochondrial Ca(2+) uptake is differentially determined by the source of supplied Ca(2+).
Cell Calcium. 2010; 47(5): 433-440. Doi: 10.1016/j.ceca.2010.03.004
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2009

Donnerer, J; Liebmann, I; Schuligoi, R Capsaicin- and mustard oil-induced extracellular signal-regulated protein kinase phosphorylation in sensory neurons in vivo: effects of neurokinins 1 and 2 receptor antagonists and of a nitric oxide synthase inhibitor.
Basic Clin Pharmacol Toxicol. 2009; 104(1):11-16 Doi: 10.1111/j.1742-7843.2008.00338.x [OPEN ACCESS]
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2008

Bugger, H; Boudina, S; Hu, XX; Tuinei, J; Zaha, VG; Theobald, HA; Yun, UJ; McQueen, AP; Wayment, B; Litwin, SE; Abel, ED Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3.
Diabetes. 2008; 57(11): 2924-2932. Doi: 10.2337/db08-0079 [OPEN ACCESS]
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Poteser, M; Graziani, A; Eder, P; Yates, A; Mächler, H; Romanin, C; Groschner, K Identification of a rare subset of adipose tissue-resident progenitor cells, which express CD133 and TRPC3 as a VEGF-regulated Ca2+ entry channel.
FEBS Lett. 2008; 582(18):2696-2702 Doi: 10.1016/j.febslet.2008.06.049 [OPEN ACCESS]
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2007

Eder, P; Poteser, M; Groschner, K TRPC3: a multifunctional, pore-forming signalling molecule.
Handb Exp Pharmacol. 2007; 77-92 Doi: 10.1007/978-3-540-34891-7_4
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Eder, P; Probst, D; Rosker, C; Poteser, M; Wolinski, H; Kohlwein, SD; Romanin, C; Groschner, K Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex.
Cardiovasc Res. 2007; 73(1): 111-119. Doi: 10.1016/j.cardiores.2006.10.016 [OPEN ACCESS]
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2006

Donnerer, J; Liebmann, I The NK1 receptor antagonist SR140333 inhibits capsaicin-induced ERK phosphorylation in sensory neurons.
Pharmacology. 2006; 77(3):144-149 Doi: 10.1159/000094022
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Graziani, A; Rosker, C; Kohlwein, SD; Zhu, MX; Romanin, C; Sattler, W; Groschner, K; Poteser, M Cellular cholesterol controls TRPC3 function: evidence from a novel dominant-negative knockdown strategy.
Biochem J. 2006; 396(1): 147-155. Doi: 10.1042/BJ20051246 [OPEN ACCESS]
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Poteser, M; Graziani, A; Rosker, C; Eder, P; Derler, I; Kahr, H; Zhu, MX; Romanin, C; Groschner, K TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells.
J Biol Chem. 2006; 281(19):13588-13595 Doi: 10.1074/jbc.M512205200 [OPEN ACCESS]
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2005

Donnerer, J; Liebmann, I; Schicho, R Differential regulation of 3-beta-hydroxysteroid dehydrogenase and vanilloid receptor TRPV1 mRNA in sensory neurons by capsaicin and NGF.
PHARMACOLOGY. 2005; 73(2): 97-101. Doi: 10.1159/000081625
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2004

Groschner, K; Rosker, C; Lukas, M Role of TRP channels in oxidative stress.
Novartis Found Symp. 2004; 258(2):222-230 Doi: 10.1002/0470862580.ch16
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2000

Scandella, E; Nagl, UO; Oehl, B; Bergmann, F; Gschwentner, M; Fürst, J; Schmarda, A; Ritter, M; Waldegger, S; Lang, F; Deetjen, P; Paulmichl, M The promoter for constitutive expression of the human ICln gene CLNS1A.
J Biol Chem. 2000; 275(21):15613-15620 Doi: 10.1074/jbc.275.21.15613 [OPEN ACCESS]
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1999

Balzer, M; Lintschinger, B; Groschner, K Evidence for a role of Trp proteins in the oxidative stress-induced membrane conductances of porcine aortic endothelial cells.
Cardiovasc Res. 1999; 42(2):543-549 Doi: 10.1016/S0008-6363(99)00025-5 [OPEN ACCESS]
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1991

Schreibmayer, W; Waller, M Domain specialization in voltage-dependent Na+ and Ca2+ channels.
J THEOR BIOL . 1991; 151(1): 141-143. Doi: 10.1016/S0022-5193(05)80148-1
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