Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: HEP G2 CELLS - , . Treffer: 29

2019

Zhu, XG; Nicholson Puthenveedu, S; Shen, Y; La, K; Ozlu, C; Wang, T; Klompstra, D; Gultekin, Y; Chi, J; Fidelin, J; Peng, T; Molina, H; Hang, HC; Min, W; Birsoy, K CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4.
MOL CELL. 2019; 74(1): 45-58. [OPEN ACCESS]
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2018

Ramirez, T; Strigun, A; Verlohner, A; Huener, HA; Peter, E; Herold, M; Bordag, N; Mellert, W; Walk, T; Spitzer, M; Jiang, X; Sperber, S; Hofmann, T; Hartung, T; Kamp, H; van Ravenzwaay, B Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.
Arch Toxicol. 2018; 92(2): 893-906. [OPEN ACCESS]
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2017

Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 [OPEN ACCESS]
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Görtz, M; Galli, U; Longerich, T; Zöller, M; Erb, U; Schemmer, P De novo synthesis of C4.4A in hepatocellular carcinoma promotes migration and invasion of tumor cells.
Oncol Rep. 2017; 38(5):2697-2704 [OPEN ACCESS]
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Nelson, ME; Lahiri, S; Chow, JD; Byrne, FL; Hargett, SR; Breen, DS; Olzomer, EM; Wu, LE; Cooney, GJ; Turner, N; James, DE; Slack-Davis, JK; Lackner, C; Caldwell, SH; Hoehn, KL Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.
Nat Commun. 2017; 8(6):14689-14689 [OPEN ACCESS]
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Prokesch, A; Graef, FA; Madl, T; Kahlhofer, J; Heidenreich, S; Schumann, A; Moyschewitz, E; Pristoynik, P; Blaschitz, A; Knauer, M; Muenzner, M; Bogner-Strauss, JG; Dohr, G; Schulz, TJ; Schupp, M Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
FASEB J. 2017; 31(2):732-742 [OPEN ACCESS]
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2016

Robier, C; Amouzadeh-Ghadikolai, O; Stettin, M; Reicht, G Comparison of the clinical utility of the Elia CTD Screen to indirect immunofluorescence on Hep-2 cells.
Clin Chem Lab Med. 2016; 54(8):1365-1370
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2015

Bitter, A; Rümmele, P; Klein, K; Kandel, BA; Rieger, JK; Nüssler, AK; Zanger, UM; Trauner, M; Schwab, M; Burk, O Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms.
Arch Toxicol. 2015; 89(11):2089-2103
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Dražić, T; Sachdev, V; Leopold, C; Patankar, JV; Malnar, M; Hećimović, S; Levak-Frank, S; Habuš, I; Kratky, D Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors.
Bioorg Med Chem. 2015; 23(10):2353-2359 [OPEN ACCESS]
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Kessler, SM; Laggai, S; Barghash, A; Schultheiss, CS; Lederer, E; Artl, M; Helms, V; Haybaeck, J; Kiemer, AK IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.
Cell Death Dis. 2015; 6(1):e1894-e1894 [OPEN ACCESS]
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Reichl, P; Fang, M; Starlinger, P; Staufer, K; Nenutil, R; Muller, P; Greplova, K; Valik, D; Dooley, S; Brostjan, C; Gruenberger, T; Shen, J; Man, K; Trauner, M; Yu, J; Gao, CF; Mikulits, W Multicenter analysis of soluble Axl reveals diagnostic value for very early stage hepatocellular carcinoma.
Int J Cancer. 2015; 137(2):385-394 [OPEN ACCESS]
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2014

Dražić, T; Molčanov, K; Sachdev, V; Malnar, M; Hećimović, S; Patankar, JV; Obrowsky, S; Levak-Frank, S; Habuš, I; Kratky, D Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors.
Eur J Med Chem. 2014; 87(9):722-734 [OPEN ACCESS]
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Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12):2393-2403 [OPEN ACCESS]
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Röhrl, C; Eigner, K; Winter, K; Korbelius, M; Obrowsky, S; Kratky, D; Kovacs, WJ; Stangl, H Endoplasmic reticulum stress impairs cholesterol efflux and synthesis in hepatic cells.
J Lipid Res. 2014; 55(1):94-103 [OPEN ACCESS]
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Vinod, M; Chennamsetty, I; Colin, S; Belloy, L; De Paoli, F; Schaider, H; Graier, WF; Frank, S; Kratky, D; Staels, B; Chinetti-Gbaguidi, G; Kostner, GM miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages.
Biochim Biophys Acta. 2014; 1841(6):827-835 [OPEN ACCESS]
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Welte, S; Urbanik, T; Elßner, C; Kautz, N; Koehler, BC; Waldburger, N; Bermejo, JL; Pinna, F; Weiss, KH; Schemmer, P; Jaeger, D; Longerich, T; Breuhahn, K; Schulze-Bergkamen, H Nuclear expression of the deubiquitinase CYLD is associated with improved survival in human hepatocellular carcinoma.
PLoS One. 2014; 9(10):e110591-e110591 [OPEN ACCESS]
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2013

Aigelsreiter, A; Ress, AL; Bettermann, K; Schauer, S; Koller, K; Eisner, F; Kiesslich, T; Stojakovic, T; Samonigg, H; Kornprat, P; Lackner, C; Haybaeck, J; Pichler, M Low expression of the putative tumour suppressor spinophilin is associated with higher proliferative activity and poor prognosis in patients with hepatocellular carcinoma.
Br J Cancer. 2013; 108(9):1830-1837 [OPEN ACCESS]
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Huber, MD; Vesely, PW; Datta, K; Gerace, L Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.
J Cell Biol. 2013; 203(3):427-436 [OPEN ACCESS]
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Yu, A; Zheng, Y; Zhang, R; Huang, J; Zhu, Z; Zhou, R; Jin, D; Yang, Z Resistin impairs SIRT1 function and induces senescence-associated phenotype in hepatocytes.
Mol Cell Endocrinol. 2013; 377(1-2):23-32
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2012

Chennamsetty, I; Kostner, KM; Claudel, T; Vinod, M; Frank, S; Weiss, TS; Trauner, M; Kostner, GM Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice.
J Lipid Res. 2012; 53(11):2405-2412 [OPEN ACCESS]
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Huppke, P; Brendel, C; Kalscheuer, V; Korenke, GC; Marquardt, I; Freisinger, P; Christodoulou, J; Hillebrand, M; Pitelet, G; Wilson, C; Gruber-Sedlmayr, U; Ullmann, R; Haas, S; Elpeleg, O; Nürnberg, G; Nürnberg, P; Dad, S; Mller, LB; Kaler, SG; Gärtner, J Mutations in SLC33A1 cause a lethal autosomal-recessive disorder with congenital cataracts, hearing loss, and low serum copper and ceruloplasmin.
AM J HUM GENET. 2012; 90(1): 61-68. [OPEN ACCESS]
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Kumari, M; Schoiswohl, G; Chitraju, C; Paar, M; Cornaciu, I; Rangrez, AY; Wongsiriroj, N; Nagy, HM; Ivanova, PT; Scott, SA; Knittelfelder, O; Rechberger, GN; Birner-Gruenberger, R; Eder, S; Brown, HA; Haemmerle, G; Oberer, M; Lass, A; Kershaw, EE; Zimmermann, R; Zechner, R Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
Cell Metab. 2012; 15(5):691-702 [OPEN ACCESS]
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Radnai, B; Antus, C; Racz, B; Engelmann, P; Priber, JK; Tucsek, Z; Veres, B; Turi, Z; Lorand, T; Sumegi, B; Gallyas, F Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation.
Mol Cancer. 2012; 11(5): 34-34. [OPEN ACCESS]
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Rohrl, C; Meisslitzer-Ruppitsch, C; Bittman, R; Li, ZG; Pabst, G; Prassl, R; Strobl, W; Neumuller, J; Ellinger, A; Pavelka, M; Stangl, H Combined Light and Electron Microscopy Using Diaminobenzidine Photooxidation to Monitor Trafficking of Lipids Derived from Lipoprotein Particles
CURR PHARM BIOTECHNO. 2012; 13(2): 331-340. [OPEN ACCESS]
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Scholler, M; Wadsack, C; Lang, I; Etschmaier, K; Schweinzer, C; Marsche, G; Dieber-Rotheneder, M; Desoye, G; Panzenboeck, U Phospholipid transfer protein in the placental endothelium is affected by gestational diabetes mellitus.
J Clin Endocrinol Metab. 2012; 97(2): 437-445. [OPEN ACCESS]
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2011

Balic, M; Rapp, N; Stanzer, S; Lin, H; Strutz, J; Szkandera, J; Daidone, MG; Samonigg, H; Cote, RJ; Dandachi, N Novel immunofluorescence protocol for multimarker assessment of putative disseminating breast cancer stem cells.
Appl Immunohistochem Mol Morphol. 2011; 19(1):33-40
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Bhat, V; Girimaji, SC; Mohan, G; Arvinda, HR; Singhmar, P; Duvvari, MR; Kumar, A Mutations in WDR62, encoding a centrosomal and nuclear protein, in Indian primary microcephaly families with cortical malformations.
Clin Genet. 2011; 80(6): 532-540.
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Pfeifer, T; Buchebner, M; Chandak, PG; Patankar, J; Kratzer, A; Obrowsky, S; Rechberger, GN; Kadam, RS; Kompella, UB; Kostner, GM; Kratky, D; Levak-Frank, S Synthetic LXR agonist suppresses endogenous cholesterol biosynthesis and efficiently lowers plasma cholesterol.
Curr Pharm Biotechnol. 2011; 12(2):285-292 [OPEN ACCESS]
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2010

Mullen, PJ; Lüscher, B; Scharnagl, H; Krähenbühl, S; Brecht, K Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy.
Biochem Pharmacol. 2010; 79(8): 1200-1209.
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