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Publikationen

Suchbegriffe: HEART FAILURE - PHYSIOPATHOLOGY , . Treffer: 80

2022

Rech, L; Abdellatif, M; Pöttler, M; Stangl, V; Mabotuwana, N; Hardy, S; Rainer, PP Small molecule STING inhibition improves myocardial infarction remodeling.
Life Sci. 2022; 291:120263 Doi: 10.1016/j.lfs.2021.120263
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2021

Heringlake, M; Alvarez, J; Bettex, D; Bouchez, S; Fruhwald, S; Girardis, M; Grossini, E; Guarracino, F; Herpain, A; Toller, W; Tritapepe, L; Pollesello, P An update on levosimendan in acute cardiac care: applications and recommendations for optimal efficacy and safety.
EXPERT REV CARDIOVAS. 2021; 19(4): 325-335. Doi: 10.1080/14779072.2021.1905520 [OPEN ACCESS]
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2020

Maron, BA; Kovacs, G; Vaidya, A; Bhatt, DL; Nishimura, RA; Mak, S; Guazzi, M; Tedford, RJ Cardiopulmonary Hemodynamics in Pulmonary Hypertension and Heart Failure: JACC Review Topic of the Week.
J AM COLL CARDIOL. 2020; 76(22): 2671-2681. Doi: 10.1016/j.jacc.2020.10.007 [OPEN ACCESS]
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Strocchi, M; Augustin, CM; Gsell, MAF; Karabelas, E; Neic, A; Gillette, K; Razeghi, O; Prassl, AJ; Vigmond, EJ; Behar, JM; Gould, J; Sidhu, B; Rinaldi, CA; Bishop, MJ; Plank, G; Niederer, SA A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations.
PLoS One. 2020; 15(6):e0235145 Doi: 10.1371/journal.pone.0235145 [OPEN ACCESS]
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2019

Belyavskiy, E; Morris, DA; Url-Michitsch, M; Verheyen, N; Meinitzer, A; Radhakrishnan, AK; Kropf, M; Frydas, A; Ovchinnikov, AG; Schmidt, A; Tadic, M; Genger, M; Lindhorst, R; Bobenko, A; Tschöpe, C; Edelmann, F; Pieske-Kraigher, E; Pieske, B Diastolic stress test echocardiography in patients with suspected heart failure with preserved ejection fraction: a pilot study.
ESC Heart Fail. 2019; 6(1):146-153 Doi: 10.1002/ehf2.12375 [OPEN ACCESS]
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Canepa, M; Franssen, FME; Olschewski, H; Lainscak, M; Böhm, M; Tavazzi, L; Rosenkranz, S Diagnostic and Therapeutic Gaps in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease.
JACC Heart Fail. 2019; 7(10):823-833 Doi: 10.1016/j.jchf.2019.05.009 [OPEN ACCESS]
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Primessnig, U; Bracic, T; Levijoki, J; Otsomaa, L; Pollesello, P; Falcke, M; Pieske, B; Heinzel, FR Long-term effects of Na⁺ /Ca²⁺ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction.
Eur J Heart Fail. 2019; 21(12):1543-1552 Doi: 10.1002/ejhf.1619 [OPEN ACCESS]
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2018

Koentges, C; Pepin, ME; Müsse, C; Pfeil, K; Alvarez, SVV; Hoppe, N; Hoffmann, MM; Odening, KE; Sossalla, S; Zirlik, A; Hein, L; Bode, C; Wende, AR; Bugger, H Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans.
Basic Res Cardiol. 2018; 113(1):8-8 Doi: 10.1007/s00395-017-0666-6 [OPEN ACCESS]
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Lourenço, AP; Leite-Moreira, AF; Balligand, JL; Bauersachs, J; Dawson, D; de Boer, RA; de Windt, LJ; Falcão-Pires, I; Fontes-Carvalho, R; Franz, S; Giacca, M; Hilfiker-Kleiner, D; Hirsch, E; Maack, C; Mayr, M; Pieske, B; Thum, T; Tocchetti, CG; Brutsaert, DL; Heymans, S An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.
Eur J Heart Fail. 2018; 20(2):216-227 Doi: 10.1002/ejhf.1059 [OPEN ACCESS]
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2017

Lee, AW; Crozier, A; Hyde, ER; Lamata, P; Truong, M; Sohal, M; Jackson, T; Behar, JM; Claridge, S; Shetty, A; Sammut, E; Plank, G; Rinaldi, CA; Niederer, S Biophysical Modeling to Determine the Optimization of Left Ventricular Pacing Site and AV/VV Delays in the Acute and Chronic Phase of Cardiac Resynchronization Therapy.
J Cardiovasc Electrophysiol. 2017; 28(2):208-215 Doi: 10.1111/jce.13134 [OPEN ACCESS]
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Skrabal, F; Pichler, GP; Penatzer, M; Steinbichl, J; Hanserl, AK; Leis, A; Loibner, H The Combyn™ ECG: Adding haemodynamic and fluid leads for the ECG. Part II: Prediction of total body water (TBW), extracellular fluid (ECF), ECF overload, fat mass (FM) and "dry" appendicular muscle mass (AppMM).
Med Eng Phys. 2017; 44(8):44-52 Doi: 10.1016/j.medengphy.2017.03.002
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Winter, MP; Kleber, ME; Koller, L; Sulzgruber, P; Scharnagl, H; Delgado, G; Goliasch, G; März, W; Niessner, A Prognostic significance of tPA/PAI-1 complex in patients with heart failure and preserved ejection fraction.
Thromb Haemost. 2017; 117(3):471-478 Doi: 10.1160/TH16-08-0600
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2016

Abdellatif, M; Leite, S; Alaa, M; Oliveira-Pinto, J; Tavares-Silva, M; Fontoura, D; Falcão-Pires, I; Leite-Moreira, AF; Lourenço, AP Spectral transfer function analysis of respiratory hemodynamic fluctuations predicts end-diastolic stiffness in preserved ejection fraction heart failure.
Am J Physiol Heart Circ Physiol. 2016; 310(1):H4-13 Doi: 10.1152/ajpheart.00399.2015 [OPEN ACCESS]
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Catena, C; Colussi, G; Verheyen, ND; Novello, M; Fagotto, V; Soardo, G; Sechi, LA Moderate Alcohol Consumption Is Associated With Left Ventricular Diastolic Dysfunction in Nonalcoholic Hypertensive Patients.
Hypertension. 2016; 68(5):1208-1216 Doi: 10.1161/HYPERTENSIONAHA.116.08145 [OPEN ACCESS]
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Crespo-Leiro, MG; Anker, SD; Maggioni, AP; Coats, AJ; Filippatos, G; Ruschitzka, F; Ferrari, R; Piepoli, MF; Delgado Jimenez, JF; Metra, M; Fonseca, C; Hradec, J; Amir, O; Logeart, D; Dahlström, U; Merkely, B; Drozdz, J; Goncalvesova, E; Hassanein, M; Chioncel, O; Lainscak, M; Seferovic, PM; Tousoulis, D; Kavoliuniene, A; Fruhwald, F; Fazlibegovic, E; Temizhan, A; Gatzov, P; Erglis, A; Laroche, C; Mebazaa, A; Heart Failure Association (HFA) of the European Society of Cardiology (ESC) European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-year follow-up outcomes and differences across regions.
Eur J Heart Fail. 2016; 18(6):613-625 Doi: 10.1002/ejhf.566 [OPEN ACCESS]
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Crozier, A; Blazevic, B; Lamata, P; Plank, G; Ginks, M; Duckett, S; Sohal, M; Shetty, A; Rinaldi, CA; Razavi, R; Niederer, SA; Smith, NP Analysis of lead placement optimization metrics in cardiac resynchronization therapy with computational modelling.
Europace. 2016; 18(suppl 4):iv113-iv120-iv113-iv120 Doi: 10.1093/europace/euw366 [OPEN ACCESS]
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Crozier, A; Blazevic, B; Lamata, P; Plank, G; Ginks, M; Duckett, S; Sohal, M; Shetty, A; Rinaldi, CA; Razavi, R; Smith, NP; Niederer, SA The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study.
J Mol Cell Cardiol. 2016; 96(7):93-100 Doi: 10.1016/j.yjmcc.2015.10.026 [OPEN ACCESS]
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Fruhwald, S; Pollesello, P; Fruhwald, F Advanced heart failure: an appraisal of the potential of levosimendan in this end-stage scenario and some related ethical considerations.
Expert Rev Cardiovasc Ther. 2016; 14(12):1335-1347 Doi: 10.1080/14779072.2016.1247694 [OPEN ACCESS]
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Primessnig, U; Schönleitner, P; Höll, A; Pfeiffer, S; Bracic, T; Rau, T; Kapl, M; Stojakovic, T; Glasnov, T; Leineweber, K; Wakula, P; Antoons, G; Pieske, B; Heinzel, FR Novel pathomechanisms of cardiomyocyte dysfunction in a model of heart failure with preserved ejection fraction.
Eur J Heart Fail. 2016; 18(8):987-997 Doi: 10.1002/ejhf.524 [OPEN ACCESS]
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Zittermann, A; Ernst, JB; Pilz, S; Dreier, J; Kuhn, J; Knabbe, C; Gummert, JF; Morshuis, M; Milting, H Calciotropic and Phosphaturic Hormones in End-Stage Heart Failure Patients Supported by a Left-Ventricular Assist Device.
PLoS One. 2016; 11(10):e0164459-e0164459 Doi: 10.1371/journal.pone.0164459 [OPEN ACCESS]
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2015

Campos, FO; Shiferaw, Y; Prassl, AJ; Boyle, PM; Vigmond, EJ; Plank, G Stochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic load.
Cardiovasc Res. 2015; 107(1):175-183 Doi: 10.1093/cvr/cvv149 [OPEN ACCESS]
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Ferrari, R; Böhm, M; Cleland, JG; Paulus, WJ; Pieske, B; Rapezzi, C; Tavazzi, L Heart failure with preserved ejection fraction: uncertainties and dilemmas.
Eur J Heart Fail. 2015; 17(7):665-671 Doi: 10.1002/ejhf.304 [OPEN ACCESS]
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Heinzel, FR; Hohendanner, F; Jin, G; Sedej, S; Edelmann, F Myocardial hypertrophy and its role in heart failure with preserved ejection fraction.
J Appl Physiol (1985). 2015; 119(10):1233-1242 Doi: 10.1152/japplphysiol.00374.2015 [OPEN ACCESS]
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Hyde, ER; Behar, JM; Claridge, S; Jackson, T; Lee, AW; Remme, EW; Sohal, M; Plank, G; Razavi, R; Rinaldi, CA; Niederer, SA Beneficial Effect on Cardiac Resynchronization From Left Ventricular Endocardial Pacing Is Mediated by Early Access to High Conduction Velocity Tissue: Electrophysiological Simulation Study.
Circ Arrhythm Electrophysiol. 2015; 8(5):1164-1172 Doi: 10.1161/CIRCEP.115.002677 [OPEN ACCESS]
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Koller, L; Kleber, ME; Brandenburg, VM; Goliasch, G; Richter, B; Sulzgruber, P; Scharnagl, H; Silbernagel, G; Grammer, TB; Delgado, G; Tomaschitz, A; Pilz, S; Berger, R; Mörtl, D; Hülsmann, M; Pacher, R; März, W; Niessner, A Fibroblast Growth Factor 23 Is an Independent and Specific Predictor of Mortality in Patients With Heart Failure and Reduced Ejection Fraction.
Circ Heart Fail. 2015; 8(6):1059-1067 Doi: 10.1161/CIRCHEARTFAILURE.115.002341 [OPEN ACCESS]
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Leite, S; Oliveira-Pinto, J; Tavares-Silva, M; Abdellatif, M; Fontoura, D; Falcão-Pires, I; Leite-Moreira, AF; Lourenço, AP Echocardiography and invasive hemodynamics during stress testing for diagnosis of heart failure with preserved ejection fraction: an experimental study.
Am J Physiol Heart Circ Physiol. 2015; 308(12): H1556-H1563. Doi: 10.1152/ajpheart.00076.2015 [OPEN ACCESS]
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Leite, S; Rodrigues, S; Tavares-Silva, M; Oliveira-Pinto, J; Alaa, M; Abdellatif, M; Fontoura, D; Falcão-Pires, I; Gillebert, TC; Leite-Moreira, AF; Lourenço, AP Afterload-induced diastolic dysfunction contributes to high filling pressures in experimental heart failure with preserved ejection fraction.
Am J Physiol Heart Circ Physiol. 2015; 309(10):H1648-H1654 Doi: 10.1152/ajpheart.00397.2015 [OPEN ACCESS]
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Lip, GY; Heinzel, FR; Gaita, F; Juanatey, JR; Le Heuzey, JY; Potpara, T; Svendsen, JH; Vos, MA; Anker, SD; Coats, AJ; Haverkamp, W; Manolis, AS; Chung, MK; Sanders, P; Pieske, B European Heart Rhythm Association/Heart Failure Association joint consensus document on arrhythmias in heart failure, endorsed by the Heart Rhythm Society and the Asia Pacific Heart Rhythm Society.
Eur J Heart Fail. 2015; 17(9):848-874 Doi: 10.1002/ejhf.338 [OPEN ACCESS]
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Ljubojevic, S; Bers, DM Nuclear calcium in cardiac myocytes.
J Cardiovasc Pharmacol. 2015; 65(3):211-217 Doi: 10.1097/FJC.0000000000000174 [OPEN ACCESS]
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Spiliopoulos, S; Autschbach, R; Koerfer, R; Tenderich, G Delayed sternal closure after total artificial heart implantation.
J Thorac Cardiovasc Surg. 2015; 150(2):417-418 Doi: 10.1016/j.jtcvs.2015.04.057 [OPEN ACCESS]
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Spiliopoulos, S; Dimitriou, AM; Serrano, MR; Guersoy, D; Autschbach, R; Goetzenich, A; Koerfer, R; Tenderich, G Percutaneous dilatational tracheostomy following total artificial heart implantation.
Interact Cardiovasc Thorac Surg. 2015; 21(1):117-118 Doi: 10.1093/icvts/ivv071 [OPEN ACCESS]
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2014

Cramer, L; Hildebrandt, B; Kung, T; Wichmann, K; Springer, J; Doehner, W; Sandek, A; Valentova, M; Stojakovic, T; Scharnagl, H; Riess, H; Anker, SD; von Haehling, S Cardiovascular function and predictors of exercise capacity in patients with colorectal cancer.
J Am Coll Cardiol. 2014; 64(13):1310-1319 Doi: 10.1016/j.jacc.2014.07.948 [OPEN ACCESS]
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Dorfs, S; Zeh, W; Hochholzer, W; Jander, N; Kienzle, RP; Pieske, B; Neumann, FJ Pulmonary capillary wedge pressure during exercise and long-term mortality in patients with suspected heart failure with preserved ejection fraction.
Eur Heart J. 2014; 35(44):3103-3112 Doi: 10.1093/eurheartj/ehu315 [OPEN ACCESS]
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Gori, M; Lam, CS; Gupta, DK; Santos, AB; Cheng, S; Shah, AM; Claggett, B; Zile, MR; Kraigher-Krainer, E; Pieske, B; Voors, AA; Packer, M; Bransford, T; Lefkowitz, M; McMurray, JJ; Solomon, SD; PARAMOUNT Investigators Sex-specific cardiovascular structure and function in heart failure with preserved ejection fraction.
Eur J Heart Fail. 2014; 16(5):535-542 Doi: 10.1002/ejhf.67 [OPEN ACCESS]
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Jhund, PS; Claggett, B; Packer, M; Zile, MR; Voors, AA; Pieske, B; Lefkowitz, M; Shi, V; Bransford, T; McMurray, JJ; Solomon, SD Independence of the blood pressure lowering effect and efficacy of the angiotensin receptor neprilysin inhibitor, LCZ696, in patients with heart failure with preserved ejection fraction: an analysis of the PARAMOUNT trial.
Eur J Heart Fail. 2014; 16(6):671-677 Doi: 10.1002/ejhf.76 [OPEN ACCESS]
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Jhund, PS; Claggett, BL; Voors, AA; Zile, MR; Packer, M; Pieske, BM; Kraigher-Krainer, E; Shah, AM; Prescott, MF; Shi, V; Lefkowitz, M; McMurray, JJ; Solomon, SD; PARAMOUNT Investigators Elevation in high-sensitivity troponin T in heart failure and preserved ejection fraction and influence of treatment with the angiotensin receptor neprilysin inhibitor LCZ696.
Circ Heart Fail. 2014; 7(6):953-959 Doi: 10.1161/CIRCHEARTFAILURE.114.001427 [OPEN ACCESS]
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Rossi, A; Gheorghiade, M; Triposkiadis, F; Solomon, SD; Pieske, B; Butler, J Left atrium in heart failure with preserved ejection fraction: structure, function, and significance.
Circ Heart Fail. 2014; 7(6):1042-1049 Doi: 10.1161/CIRCHEARTFAILURE.114.001276 [OPEN ACCESS]
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Senni, M; Paulus, WJ; Gavazzi, A; Fraser, AG; Díez, J; Solomon, SD; Smiseth, OA; Guazzi, M; Lam, CS; Maggioni, AP; Tschöpe, C; Metra, M; Hummel, SL; Edelmann, F; Ambrosio, G; Stewart Coats, AJ; Filippatos, GS; Gheorghiade, M; Anker, SD; Levy, D; Pfeffer, MA; Stough, WG; Pieske, BM New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes.
Eur Heart J. 2014; 35(40):2797-2815 Doi: 10.1093/eurheartj/ehu204 [OPEN ACCESS]
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Skrabal, F; Pichler, GP; Gratze, G; Holler, A Adding "hemodynamic and fluid leads" to the ECG. Part I: the electrical estimation of BNP, chronic heart failure (CHF) and extracellular fluid (ECF) accumulation.
MED ENG PHYS. 2014; 36(7): 896-904. Doi: 10.1016/j.medengphy.2014.03.015
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Spiliopoulos, S; Koerfer, R; Tenderich, G A first step beyond traditional boundaries: destination therapy with the SynCardia total artificial heart.
Interact Cardiovasc Thorac Surg. 2014; 18(6):855-856 Doi: 10.1093/icvts/ivu065 (- Case Report) [OPEN ACCESS]
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Walton, RD; Martinez, ME; Bishop, MJ; Hocini, M; Haïssaguerre, M; Plank, G; Bernus, O; Vigmond, EJ Influence of the Purkinje-muscle junction on transmural repolarization heterogeneity.
Cardiovasc Res. 2014; 103(4):629-640 Doi: 10.1093/cvr/cvu165 [OPEN ACCESS]
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2013

Ellwein, LM; Pope, SR; Xie, A; Batzel, JJ; Kelley, CT; Olufsen, MS Patient-specific modeling of cardiovascular and respiratory dynamics during hypercapnia.
Math Biosci. 2013; 241(1):56-74 Doi: 10.1016/j.mbs.2012.09.003 [OPEN ACCESS]
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Hohendanner, F; Ljubojević, S; MacQuaide, N; Sacherer, M; Sedej, S; Biesmans, L; Wakula, P; Platzer, D; Sokolow, S; Herchuelz, A; Antoons, G; Sipido, K; Pieske, B; Heinzel, FR Intracellular dyssynchrony of diastolic cytosolic [Ca²⁺] decay in ventricular cardiomyocytes in cardiac remodeling and human heart failure.
Circ Res. 2013; 113(5):527-538 Doi: 10.1161/CIRCRESAHA.113.300895 [OPEN ACCESS]
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Loforte, A; Stepanenko, A; Potapov, EV; Musumeci, F; Dranishnikov, N; Schweiger, M; Montalto, A; Pasic, M; Weng, Y; Dandel, M; Siniawski, H; Kukucka, M; Krabatsch, T; Hetzer, R Temporary right ventricular mechanical support in high-risk left ventricular assist device recipients versus permanent biventricular or total artificial heart support.
Artif Organs. 2013; 37(6):523-530 Doi: 10.1111/aor.12038 [OPEN ACCESS]
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2012

Solomon, SD; Zile, M; Pieske, B; Voors, A; Shah, A; Kraigher-Krainer, E; Shi, V; Bransford, T; Takeuchi, M; Gong, JJ; Lefkowitz, M; Packer, M; McMurray, JJV; The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial.
LANCET. 2012; 380(9851): 1387-1395. Doi: 10.1016/S0140-6736(12)61227-6
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Tomaschitz, A; Ritz, E; Pieske, B; Fahrleitner-Pammer, A; Kienreich, K; Horina, JH; Drechsler, C; März, W; Ofner, M; Pieber, TR; Pilz, S Aldosterone and parathyroid hormone: a precarious couple for cardiovascular disease.
Cardiovasc Res. 2012; 94(1):10-19 Doi: 10.1093/cvr/cvs092 [OPEN ACCESS]
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2011

Batzel, JJ; Ellwein, L; Olufsen, MS Modeling cardio-respiratory system response to inhaled CO2 in patients with congestive heart failure.
Conf Proc IEEE Eng Med Biol Soc. 2011; 2011(5): 2418-2421. Doi: 10.1109/IEMBS.2011.6090673
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Bugger, H; Guzman, C; Zechner, C; Palmeri, M; Russell, KS; Russell, RR Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation.
Cancer Chemother Pharmacol. 2011; 67(6): 1381-1388. Doi: 10.1007/s00280-010-1441-7 [OPEN ACCESS]
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Edelmann, F; Stahrenberg, R; Gelbrich, G; Durstewitz, K; Angermann, CE; Düngen, HD; Scheffold, T; Zugck, C; Maisch, B; Regitz-Zagrosek, V; Hasenfuss, G; Pieske, BM; Wachter, R Contribution of comorbidities to functional impairment is higher in heart failure with preserved than with reduced ejection fraction.
Clin Res Cardiol. 2011; 100(9):755-764 Doi: 10.1007/s00392-011-0305-4 [OPEN ACCESS]
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Knöll, R; Linke, WA; Zou, P; Miocic, S; Kostin, S; Buyandelger, B; Ku, CH; Neef, S; Bug, M; Schäfer, K; Knöll, G; Felkin, LE; Wessels, J; Toischer, K; Hagn, F; Kessler, H; Didié, M; Quentin, T; Maier, LS; Teucher, N; Unsöld, B; Schmidt, A; Birks, EJ; Gunkel, S; Lang, P; Granzier, H; Zimmermann, WH; Field, LJ; Faulkner, G; Dobbelstein, M; Barton, PJ; Sattler, M; Wilmanns, M; Chien, KR Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart.
Circ Res. 2011; 109(7):758-769 Doi: 10.1161/CIRCRESAHA.111.245787 [OPEN ACCESS]
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