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Publikationen

Suchbegriffe: HEK293 CELLS - , . Treffer: 84

2021

Frei, R; Nordlohne, J; Hüser, U; Hild, S; Schmidt, J; Eitner, F; Grundmann, M Allosteric targeting of the FFA2 receptor (GPR43) restores responsiveness of desensitized human neutrophils.
J Leukoc Biol. 2021; 109(4):741-751 Doi: 10.1002/JLB.2A0720-432R [OPEN ACCESS]
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2020

Caratelli, S; Arriga, R; Sconocchia, T; Ottaviani, A; Lanzilli, G; Pastore, D; Cenciarelli, C; Venditti, A; Del Principe, MI; Lauro, D; Landoni, E; Du, H; Savoldo, B; Ferrone, S; Dotti, G; Sconocchia, G In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab.
Int J Cancer. 2020; 146(1):236-247 Doi: 10.1002/ijc.32663 [OPEN ACCESS]
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2019

Bandleon, S; Strunz, PP; Pickel, S; Tiapko, O; Cellini, A; Miranda-Laferte, E; Eder-Negrin, P FKBP52 regulates TRPC3-dependent Ca²⁺ signals and the hypertrophic growth of cardiomyocyte cultures.
J Cell Sci. 2019; 132(20): Doi: 10.1242/jcs.231506 [OPEN ACCESS]
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Begemann, A; Acuña, MA; Zweier, M; Vincent, M; Steindl, K; Bachmann-Gagescu, R; Hackenberg, A; Abela, L; Plecko, B; Kroell-Seger, J; Baumer, A; Yamakawa, K; Inoue, Y; Asadollahi, R; Sticht, H; Zeilhofer, HU; Rauch, A Further corroboration of distinct functional features in SCN2A variants causing intellectual disability or epileptic phenotypes.
MOL MED. 2019; 25(1): 6-6. Doi: 10.1186/s10020-019-0073-6 [OPEN ACCESS]
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Gottschalk, B; Klec, C; Leitinger, G; Bernhart, E; Rost, R; Bischof, H; Madreiter-Sokolowski, CT; Radulović, S; Eroglu, E; Sattler, W; Waldeck-Weiermair, M; Malli, R; Graier, WF MICU1 controls cristae junction and spatially anchors mitochondrial Ca²⁺ uniporter complex.
Nat Commun. 2019; 10(1):3732-3732 Doi: 10.1038/s41467-019-11692-x [OPEN ACCESS]
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Hughes, MM; Hooftman, A; Angiari, S; Tummala, P; Zaslona, Z; Runtsch, MC; McGettrick, AF; Sutton, CE; Diskin, C; Rooke, M; Takahashi, S; Sundararaj, S; Casarotto, MG; Dahlstrom, JE; Palsson-McDermott, EM; Corr, SC; Mills, KHG; Preston, RJS; Neamati, N; Xie, Y; Baell, JB; Board, PG; O'Neill, LAJ Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation.
Cell Rep. 2019; 29(1): 151-161. Doi: 10.1016/j.celrep.2019.08.072 [OPEN ACCESS]
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Schober, R; Bonhenry, D; Lunz, V; Zhu, J; Krizova, A; Frischauf, I; Fahrner, M; Zhang, M; Waldherr, L; Schmidt, T; Derler, I; Stathopulos, PB; Romanin, C; Ettrich, RH; Schindl, R Sequential activation of STIM1 links Ca²⁺ with luminal domain unfolding.
Sci Signal. 2019; 12(608): Doi: 10.1126/scisignal.aax3194
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Zhu, XG; Nicholson Puthenveedu, S; Shen, Y; La, K; Ozlu, C; Wang, T; Klompstra, D; Gultekin, Y; Chi, J; Fidelin, J; Peng, T; Molina, H; Hang, HC; Min, W; Birsoy, K CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4.
MOL CELL. 2019; 74(1): 45-58. Doi: 10.1016/j.molcel.2019.01.037 [OPEN ACCESS]
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2018

Early, JO; Menon, D; Wyse, CA; Cervantes-Silva, MP; Zaslona, Z; Carroll, RG; Palsson-McDermott, EM; Angiari, S; Ryan, DG; Corcoran, SE; Timmons, G; Geiger, SS; Fitzpatrick, DJ; O'Connell, D; Xavier, RJ; Hokamp, K; O'Neill, LAJ; Curtis, AM Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.
Proc Natl Acad Sci U S A. 2018; 115(36): E8460-E8468. Doi: 10.1073/pnas.1800431115 [OPEN ACCESS]
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Folci, A; Steinberger, A; Lee, B; Stanika, R; Scheruebel, S; Campiglio, M; Ramprecht, C; Pelzmann, B; Hell, JW; Obermair, GJ; Heine, M; Di Biase, V Molecular mimicking of C-terminal phosphorylation tunes the surface dynamics of Ca_V1.2 calcium channels in hippocampal neurons.
J Biol Chem. 2018; 293(3):1040-1053 Doi: 10.1074/jbc.M117.799585 [OPEN ACCESS]
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Fuchs, R; Stracke, A; Holzmann, V; Luschin-Ebengreuth, G; Meier-Allard, N; Ebner, N; Lassacher, TM; Absenger-Novak, M; Fröhlich, E; Schittmayer, M; Cano Crespo, S; Palacin, M; Rinner, B; Birner-Gruenberger, R Prazosin induced lysosomal tubulation interferes with cytokinesis and the endocytic sorting of the tumour antigen CD98hc.
Biochim Biophys Acta Mol Cell Res. 2018; 1865(9):1211-1229 Doi: 10.1016/j.bbamcr.2018.06.006 [OPEN ACCESS]
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Peinhaupt, M; Roula, D; Theiler, A; Sedej, M; Schicho, R; Marsche, G; Sturm, EM; Sabroe, I; Rothenberg, ME; Heinemann, A DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator.
J Leukoc Biol. 2018; 104(1):159-171 Doi: 10.1002/JLB.3MA1017-404R [OPEN ACCESS]
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Rengachari, S; Groiss, S; Devos, JM; Caron, E; Grandvaux, N; Panne, D Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.
Proc Natl Acad Sci U S A. 2018; 115(4): E601-E609. Doi: 10.1073/pnas.1718426115 [OPEN ACCESS]
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2017

Bedau, T; Peters, F; Prox, J; Arnold, P; Schmidt, F; Finkernagel, M; Köllmann, S; Wichert, R; Otte, A; Ohler, A; Stirnberg, M; Lucius, R; Koudelka, T; Tholey, A; Biasin, V; Pietrzik, CU; Kwapiszewska, G; Becker-Pauly, C Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration.
FASEB J. 2017; 31(3):1226-1237 Doi: 10.1096/fj.201601113R
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Chao, MP; Gentles, AJ; Chatterjee, S; Lan, F; Reinisch, A; Corces, MR; Xavy, S; Shen, J; Haag, D; Chanda, S; Sinha, R; Morganti, RM; Nishimura, T; Ameen, M; Wu, H; Wernig, M; Wu, JC; Majeti, R Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Cell Stem Cell. 2017; 20(3): 329-344. Doi: 10.1016/j.stem.2016.11.018 [OPEN ACCESS]
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Charoensin, S; Eroglu, E; Opelt, M; Bischof, H; Madreiter-Sokolowski, CT; Kirsch, A; Depaoli, MR; Frank, S; Schrammel, A; Mayer, B; Waldeck-Weiermair, M; Graier, WF; Malli, R Intact mitochondrial Ca²⁺ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS).
Free Radic Biol Med. 2017; 102(1):248-259 Doi: 10.1016/j.freeradbiomed.2016.11.049 [OPEN ACCESS]
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Eroglu, E; Rost, R; Bischof, H; Blass, S; Schreilechner, A; Gottschalk, B; Depaoli, MR; Klec, C; Charoensin, S; Madreiter-Sokolowski, CT; Ramadani, J; Waldeck-Weiermair, M; Graier, WF; Malli, R Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells.
J Vis Exp. 2017; 5(121): Doi: 10.3791/55486 [OPEN ACCESS]
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Frischauf, I; Litviňuková, M; Schober, R; Zayats, V; Svobodová, B; Bonhenry, D; Lunz, V; Cappello, S; Tociu, L; Reha, D; Stallinger, A; Hochreiter, A; Pammer, T; Butorac, C; Muik, M; Groschner, K; Bogeski, I; Ettrich, RH; Romanin, C; Schindl, R Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
Sci Signal. 2017; 10(507): Doi: 10.1126/scisignal.aao0358 [OPEN ACCESS]
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Geuens, T; De Winter, V; Rajan, N; Achsel, T; Mateiu, L; Almeida-Souza, L; Asselbergh, B; Bouhy, D; Auer-Grumbach, M; Bagni, C; Timmerman, V Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease.
Acta Neuropathol Commun. 2017; 5(1):5-5 Doi: 10.1186/s40478-016-0407-3 [OPEN ACCESS]
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Taniguchi, K; Moroishi, T; de Jong, PR; Krawczyk, M; Grebbin, BM; Luo, H; Xu, RH; Golob-Schwarzl, N; Schweiger, C; Wang, K; Di Caro, G; Feng, Y; Fearon, ER; Raz, E; Kenner, L; Farin, HF; Guan, KL; Haybaeck, J; Datz, C; Zhang, K; Karin, M YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
Proc Natl Acad Sci U S A. 2017; 114(7):1643-1648 Doi: 10.1073/pnas.1620290114 [OPEN ACCESS]
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2016

Anvarian, Z; Nojima, H; van Kappel, EC; Madl, T; Spit, M; Viertler, M; Jordens, I; Low, TY; van Scherpenzeel, RC; Kuper, I; Richter, K; Heck, AJ; Boelens, R; Vincent, JP; Rüdiger, SG; Maurice, MM Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.
Nat Struct Mol Biol. 2016; 23(4):324-332 Doi: 10.1038/nsmb.3191
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Bartuzi, P; Billadeau, DD; Favier, R; Rong, S; Dekker, D; Fedoseienko, A; Fieten, H; Wijers, M; Levels, JH; Huijkman, N; Kloosterhuis, N; van der Molen, H; Brufau, G; Groen, AK; Elliott, AM; Kuivenhoven, JA; Plecko, B; Grangl, G; McGaughran, J; Horton, JD; Burstein, E; Hofker, MH; van de Sluis, B CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Nat Commun. 2016; 7(5):10961-10961 Doi: 10.1038/ncomms10961 [OPEN ACCESS]
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Derler, I; Jardin, I; Stathopulos, PB; Muik, M; Fahrner, M; Zayats, V; Pandey, SK; Poteser, M; Lackner, B; Absolonova, M; Schindl, R; Groschner, K; Ettrich, R; Ikura, M; Romanin, C Cholesterol modulates Orai1 channel function.
Sci Signal. 2016; 9(412):ra10-ra10 Doi: 10.1126/scisignal.aad7808 [OPEN ACCESS]
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Hartmann, L; Dutta, S; Opatz, S; Vosberg, S; Reiter, K; Leubolt, G; Metzeler, KH; Herold, T; Bamopoulos, SA; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Hopfner, KP; Graf, A; Krebs, S; Blum, H; Middeke, JM; Stölzel, F; Thiede, C; Wolf, S; Bohlander, SK; Preiss, C; Chen-Wichmann, L; Wichmann, C; Sauerland, MC; Büchner, T; Berdel, WE; Wörmann, BJ; Braess, J; Hiddemann, W; Spiekermann, K; Greif, PA ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
Nat Commun. 2016; 7(1): 11733-11733. Doi: 10.1038/ncomms11733 [OPEN ACCESS]
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Hrdinka, M; Fiil, BK; Zucca, M; Leske, D; Bagola, K; Yabal, M; Elliott, PR; Damgaard, RB; Komander, D; Jost, PJ; Gyrd-Hansen, M CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling.
Cell Rep. 2016; 14(12):2846-2858 Doi: 10.1016/j.celrep.2016.02.062 [OPEN ACCESS]
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Jürets, A; Le Bras, M; Staffler, G; Stein, G; Leitner, L; Neuhofer, A; Tardelli, M; Turkof, E; Zeyda, M; Stulnig, TM Inhibition of Cellular Adhesion by Immunological Targeting of Osteopontin Neoepitopes Generated through Matrix Metalloproteinase and Thrombin Cleavage.
PLoS One. 2016; 11(2): e0148333-e0148333. Doi: 10.1371/journal.pone.0148333 [OPEN ACCESS]
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Kammerer, S; Jahn, SW; Winter, E; Eidenhammer, S; Rezania, S; Regitnig, P; Pichler, M; Schreibmayer, W; Bauernhofer, T Critical evaluation of KCNJ3 gene product detection in human breast cancer: mRNA in situ hybridisation is superior to immunohistochemistry.
J Clin Pathol. 2016; 69(12):1116-1121 Doi: 10.1136/jclinpath-2016-203798 [OPEN ACCESS]
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Mangmool, S; Denkaew, T; Phosri, S; Pinthong, D; Parichatikanond, W; Shimauchi, T; Nishida, M Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner.
Mol Endocrinol. 2016; 30(1):118-132 Doi: 10.1210/me.2015-1201 [OPEN ACCESS]
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Tiapko, O; Bacsa, B; de la Cruz, GG; Glasnov, T; Groschner, K Optopharmacological control of TRPC channels by coumarin-caged lipids is associated with a phototoxic membrane effect.
Sci China Life Sci. 2016; 59(8):802-810 Doi: 10.1007/s11427-016-5095-5 [OPEN ACCESS]
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Tuller, F; Holzer, H; Schanda, K; Aboulenein-Djamshidian, F; Höftberger, R; Khalil, M; Seifert-Held, T; Leutmezer, F; Berger, T; Reindl, M Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders.
J Neuroinflammation. 2016; 13(1):176-176 Doi: 10.1186/s12974-016-0642-3 [OPEN ACCESS]
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2015

Chromikova, V; Mader, A; Hofbauer, S; Göbl, C; Madl, T; Gach, JS; Bauernfried, S; Furtmüller, PG; Forthal, DN; Mach, L; Obinger, C; Kunert, R Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM.
Biochim Biophys Acta. 2015; 1854(10 Pt A):1536-1544 Doi: 10.1016/j.bbapap.2015.02.018 [OPEN ACCESS]
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Chung, HS; Murray, CI; Venkatraman, V; Crowgey, EL; Rainer, PP; Cole, RN; Bomgarden, RD; Rogers, JC; Balkan, W; Hare, JM; Kass, DA; Van Eyk, JE Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection.
Circ Res. 2015; 117(10):846-857 Doi: 10.1161/CIRCRESAHA.115.307336 [OPEN ACCESS]
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Crescenzo, R; Abate, F; Lasorsa, E; Tabbo', F; Gaudiano, M; Chiesa, N; Di Giacomo, F; Spaccarotella, E; Barbarossa, L; Ercole, E; Todaro, M; Boi, M; Acquaviva, A; Ficarra, E; Novero, D; Rinaldi, A; Tousseyn, T; Rosenwald, A; Kenner, L; Cerroni, L; Tzankov, A; Ponzoni, M; Paulli, M; Weisenburger, D; Chan, WC; Iqbal, J; Piris, MA; Zamo', A; Ciardullo, C; Rossi, D; Gaidano, G; Pileri, S; Tiacci, E; Falini, B; Shultz, LD; Mevellec, L; Vialard, JE; Piva, R; Bertoni, F; Rabadan, R; Inghirami, G; European T-Cell Lymphoma Study Group, T-Cell Project: Prospective Collection of Data in Patients with Peripheral T-Cell Lymphoma and the AIRC 5xMille Consortium “Genetics-Driven Targeted Management of Lymphoid Malignancies” Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.
Cancer Cell. 2015; 27(4):516-532 Doi: 10.1016/j.ccell.2015.03.006 [OPEN ACCESS]
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Frischauf, I; Zayats, V; Deix, M; Hochreiter, A; Jardin, I; Muik, M; Lackner, B; Svobodová, B; Pammer, T; Litviňuková, M; Sridhar, AA; Derler, I; Bogeski, I; Romanin, C; Ettrich, RH; Schindl, R A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription.
Sci Signal. 2015; 8(408):ra131-ra131 Doi: 10.1126/scisignal.aab1901 [OPEN ACCESS]
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Joshi, S; Wels, C; Beham-Schmid, C; Fukunaga-Kalabis, M; Holmen, SL; Otte, M; Herlyn, M; Waldhoer, M; Schaider, H Gα13 mediates human cytomegalovirus-encoded chemokine receptor US28-induced cell death in melanoma.
Int J Cancer. 2015; 137(6):1503-1508 Doi: 10.1002/ijc.29506 [OPEN ACCESS]
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Lin, AP; Abbas, S; Kim, SW; Ortega, M; Bouamar, H; Escobedo, Y; Varadarajan, P; Qin, Y; Sudderth, J; Schulz, E; Deutsch, A; Mohan, S; Ulz, P; Neumeister, P; Rakheja, D; Gao, X; Hinck, A; Weintraub, ST; DeBerardinis, RJ; Sill, H; Dahia, PL; Aguiar, RC D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2.
Nat Commun. 2015; 6(7):7768-7768 Doi: 10.1038/ncomms8768 [OPEN ACCESS]
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Milewska, M; Romano, D; Herrero, A; Guerriero, ML; Birtwistle, M; Quehenberger, F; Hatzl, S; Kholodenko, BN; Segatto, O; Kolch, W; Zebisch, A Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation.
PLoS One. 2015; 10(6):e0129859-e0129859 Doi: 10.1371/journal.pone.0129859 [OPEN ACCESS]
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Reinthaler, EM; Dejanovic, B; Lal, D; Semtner, M; Merkler, Y; Reinhold, A; Pittrich, DA; Hotzy, C; Feucht, M; Steinböck, H; Gruber-Sedlmayr, U; Ronen, GM; Neophytou, B; Geldner, J; Haberlandt, E; Muhle, H; Ikram, MA; van Duijn, CM; Uitterlinden, AG; Hofman, A; Altmüller, J; Kawalia, A; Toliat, MR; EuroEPINOMICS Consortium; Nürnberg, P; Lerche, H; Nothnagel, M; Thiele, H; Sander, T; Meier, JC; Schwarz, G; Neubauer, BA; Zimprich, F Rare variants in γ-aminobutyric acid type A receptor genes in rolandic epilepsy and related syndromes.
Ann Neurol. 2015; 77(6):972-986 Doi: 10.1002/ana.24395
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Schwamb, B; Pick, R; Fernández, SB; Völp, K; Heering, J; Dötsch, V; Bösser, S; Jung, J; Beinoraviciute-Kellner, R; Wesely, J; Zörnig, I; Hammerschmidt, M; Nowak, M; Penzel, R; Zatloukal, K; Joos, S; Rieker, RJ; Agaimy, A; Söder, S; Reid-Lombardo, KM; Kendrick, ML; Bardsley, MR; Hayashi, Y; Asuzu, DT; Syed, SA; Ordog, T; Zörnig, M FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors.
Int J Cancer. 2015; 137(6):1318-1329 Doi: 10.1002/ijc.29498 [OPEN ACCESS]
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Tchoupa, AK; Lichtenegger, S; Reidl, J; Hauck, CR Outer membrane protein P1 is the CEACAM-binding adhesin of Haemophilus influenzae.
Mol Microbiol. 2015; 98(3):440-455 Doi: 10.1111/mmi.13134 [OPEN ACCESS]
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Waldeck-Weiermair, M; Bischof, H; Blass, S; Deak, AT; Klec, C; Graier, T; Roller, C; Rost, R; Eroglu, E; Gottschalk, B; Hofmann, NA; Graier, WF; Malli, R Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum.
Sensors (Basel). 2015; 15(6):13052-13068 Doi: 10.3390/s150613052 [OPEN ACCESS]
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Waldeck-Weiermair, M; Malli, R; Parichatikanond, W; Gottschalk, B; Madreiter-Sokolowski, CT; Klec, C; Rost, R; Graier, WF Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2.).
Sci Rep. 2015; 5(50):15602-15602 Doi: 10.1038/srep15602 [OPEN ACCESS]
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Wiesner, T; Lee, W; Obenauf, AC; Ran, L; Murali, R; Zhang, QF; Wong, EW; Hu, W; Scott, SN; Shah, RH; Landa, I; Button, J; Lailler, N; Sboner, A; Gao, D; Murphy, DA; Cao, Z; Shukla, S; Hollmann, TJ; Wang, L; Borsu, L; Merghoub, T; Schwartz, GK; Postow, MA; Ariyan, CE; Fagin, JA; Zheng, D; Ladanyi, M; Busam, KJ; Berger, MF; Chen, Y; Chi, P Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Nature. 2015; 526(7573):453-457 Doi: 10.1038/nature15258 [OPEN ACCESS]
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2014

Balenga, NA; Martínez-Pinilla, E; Kargl, J; Schröder, R; Peinhaupt, M; Platzer, W; Bálint, Z; Zamarbide, M; Dopeso-Reyes, IG; Ricobaraza, A; Pérez-Ortiz, JM; Kostenis, E; Waldhoer, M; Heinemann, A; Franco, R Heteromerization of GPR55 and cannabinoid CB2 receptors modulates signalling.
Br J Pharmacol. 2014; 171(23):5387-5406 Doi: 10.1111/bph.12850 [OPEN ACCESS]
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Bast, A; Krause, K; Schmidt, IH; Pudla, M; Brakopp, S; Hopf, V; Breitbach, K; Steinmetz, I Caspase-1-dependent and -independent cell death pathways in Burkholderia pseudomallei infection of macrophages.
PLoS Pathog. 2014; 10(3): e1003986-e1003986. Doi: 10.1371/journal.ppat.1003986 [OPEN ACCESS]
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Fahrner, M; Muik, M; Schindl, R; Butorac, C; Stathopulos, P; Zheng, L; Jardin, I; Ikura, M; Romanin, C A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).
J Biol Chem. 2014; 289(48): 33231-33244. Doi: 10.1074/jbc.M114.610022 [OPEN ACCESS]
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Konya, V; Blättermann, S; Jandl, K; Platzer, W; Ottersbach, PA; Marsche, G; Gütschow, M; Kostenis, E; Heinemann, A A biased non-Gαi OXE-R antagonist demonstrates that Gαi protein subunit is not directly involved in neutrophil, eosinophil, and monocyte activation by 5-oxo-ETE.
J Immunol. 2014; 192(10):4774-4782 Doi: 10.4049/jimmunol.1302013 [OPEN ACCESS]
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Liu, X; Kunert, O; Blunder, M; Fakhrudin, N; Noha, SM; Malainer, C; Schinkovitz, A; Heiss, EH; Atanasov, AG; Kollroser, M; Schuster, D; Dirsch, VM; Bauer, R Polyyne hybrid compounds from Notopterygium incisum with peroxisome proliferator-activated receptor gamma agonistic effects.
J Nat Prod. 2014; 77(11):2513-2521 Doi: 10.1021/np500605v [OPEN ACCESS]
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Seo, K; Rainer, PP; Shalkey Hahn, V; Lee, DI; Jo, SH; Andersen, A; Liu, T; Xu, X; Willette, RN; Lepore, JJ; Marino, JP; Birnbaumer, L; Schnackenberg, CG; Kass, DA Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.
Proc Natl Acad Sci U S A. 2014; 111(4):1551-1556 Doi: 10.1073/pnas.1308963111 [OPEN ACCESS]
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Vishnu, N; Jadoon Khan, M; Karsten, F; Groschner, LN; Waldeck-Weiermair, M; Rost, R; Hallström, S; Imamura, H; Graier, WF; Malli, R ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release.
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