Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: GLIOBLASTOMA, . Treffer: 90

2023

Alcaniz, J; Winkler, L; Dahlmann, M; Becker, M; Orthmann, A; Haybaeck, J; Krassnig, S; Skofler, C; Kratzsch, T; Kuhn, SA; Jödicke, A; Linnebacher, M; Fichtner, I; Walther, W; Hoffmann, J Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Front Oncol. 2023; 13: 1129627 Doi: 10.3389/fonc.2023.1129627 [OPEN ACCESS]
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Brawanski, KR; Sprung, S; Freyschlag, CF; Hoeftberger, R; Ströbel, T; Haybaeck, J; Thomé, C; Manzl, C; Birkl-Toeglhofer, AM Influence of MMR, MGMT Promotor Methylation and Protein Expression on Overall and Progression-Free Survival in Primary Glioblastoma Patients Treated with Temozolomide.
Int J Mol Sci. 2023; 24(7): Doi: 10.3390/ijms24076184 [OPEN ACCESS]
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Ladenhauf, VK; Galijasevic, M; Kerschbaumer, J; Freyschlag, CF; Nowosielski, M; Birkl-Toeglhofer, AM; Haybaeck, J; Gizewski, ER; Mangesius, S; Grams, AE Peritumoral ADC Values Correlate with the MGMT Methylation Status in Patients with Glioblastoma.
Cancers (Basel). 2023; 15(5): Doi: 10.3390/cancers15051384 [OPEN ACCESS]
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Schwab, M; de, Trizio, I; Ghobrial, M; Shiu, JY; Sürücü, O; Girolamo, F; Errede, M; Yilmaz, M; Haybaeck, J; Moiraghi, A; Monnier, PP; Lawler, SE; Greenfield, JP; Radovanovic, I; Frei, K; Schlapbach, R; Vogel, V; Virgintino, D; De, Bock, K; Wälchli, T Nucleolin promotes angiogenesis and endothelial metabolism along the onco-fetal axis in the human brain vasculature.
JCI Insight. 2023; Doi: 10.1172/jci.insight.143071
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2022

Gkika, E; Grosu, AL; Macarulla, Mercade, T; Cubillo, Gracián, A; Brunner, TB; Schultheiß, M; Pazgan-Simon, M; Seufferlein, T; Touchefeu, Y Tumor Treating Fields Concomitant with Sorafenib in Advanced Hepatocellular Cancer: Results of the HEPANOVA Phase II Study.
Cancers (Basel). 2022; 14(6): Doi: 10.3390/cancers14061568 [OPEN ACCESS]
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Heugenhauser, J; Galijasevic, M; Mangesius, S; Goebel, G; Buchroithner, J; Erhart, F; Pichler, J; Widhalm, G; Stockhammer, G; Iglseder, S; Freyschlag, CF; Oberndorfer, S; Bordihn, K; von Campe, G; Czech, T; Surbock, B; Purkart, TU; Marosi, C; Felzmann, T; Nowosielski, M MRI Response Assessment in Glioblastoma Patients Treated with Dendritic-Cell-Based Immunotherapy
CANCERS. 2022; 14(6): 1579 Doi: 10.3390/cancers14061579 [OPEN ACCESS]
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Strickland, BA; Wedemeyer, M; Ruzevick, J; Micko, A; Shahrestani, S; Daneshmand, S; Shiroishi, MS; Hwang, DH; Attenello, F; Chen, T; Zada, G 5-Aminolevulinic acid-enhanced fluorescence-guided treatment of high-grade glioma using angled endoscopic blue light visualization: technical case series with preliminary follow-up.
J Neurosurg. 2022; 1-9 Doi: 10.3171/2022.1.JNS212562
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2021

Galijašević, M; Steiger, R; Radović, I; Birkl-Toeglhofer, AM; Birkl, C; Deeg, L; Mangesius, S; Rietzler, A; Regodić, M; Stockhammer, G; Freyschlag, CF; Kerschbaumer, J; Haybaeck, J; Grams, AE; Gizewski, ER Phosphorous Magnetic Resonance Spectroscopy and Molecular Markers in IDH1 Wild Type Glioblastoma.
Cancers (Basel). 2021; 13(14): Doi: 10.3390/cancers13143569 [OPEN ACCESS]
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Krassnig, S; Wohlrab, C; Golob-Schwarzl, N; Raicht, A; Schatz, C; Birkl-Toeglhofer, AM; Skofler, C; Gantenbein, N; Leoni, M; Asslaber, M; Leber, SL; Mahdy-Ali, K; von Campe, G; Mayer, M; Borenich, A; Weis, S; Benesch, M; Haybaeck, J A Profound Basic Characterization of eIFs in Gliomas: Identifying eIF3I and 4H as Potential Novel Target Candidates in Glioma Therapy.
Cancers (Basel). 2021; 13(6): Doi: 10.3390/cancers13061482 [OPEN ACCESS]
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Maxian, T; Gerlitz, L; Riedl, S; Rinner, B; Zweytick, D Effect of L- to D-Amino Acid Substitution on Stability and Activity of Antitumor Peptide RDP215 against Human Melanoma and Glioblastoma
INT J MOL SCI. 2021; 22(16): 8469 Doi: 10.3390/ijms22168469 [OPEN ACCESS]
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Muster, V; Gary, T Contrasts in Glioblastoma-Venous Thromboembolism versus Bleeding Risk.
Cells. 2021; 10(6): Doi: 10.3390/cells10061414 [OPEN ACCESS]
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Waldherr, L; Seitanidou, M; Jakesova, M; Handl, V; Honeder, S; Nowakowska, M; Tomin, T; Rad, MK; Schmidt, T; Distl, J; Birner-Gruenberger, R; Campe, G; Schafer, U; Berggren, M; Rinner, B; Asslaber, M; Ghaffari-Tabrizi-Wizsy, N; Patz, S; Simon, DT; Schindl, R Targeted Chemotherapy of Glioblastoma Spheroids with an Iontronic Pump
ADV MATER TECHNOL-US. 2021; 2001302 Doi: 10.1002/admt.202001302 [OPEN ACCESS]
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2020

de Sitter, A; Visser, M; Brouwer, I; Cover, KS; van Schijndel, RA; Eijgelaar, RS; Müller, DMJ; Ropele, S; Kappos, L; Rovira, Á; Filippi, M; Enzinger, C; Frederiksen, J; Ciccarelli, O; Guttmann, CRG; Wattjes, MP; Witte, MG; de Witt Hamer, PC; Barkhof, F; Vrenken, H; MAGNIMS Study Group and Alzheimer’s Disease Neuroimaging Initiative Facing privacy in neuroimaging: removing facial features degrades performance of image analysis methods.
Eur Radiol. 2020; 30(2):1062-1074 Doi: 10.1007/s00330-019-06459-3 [OPEN ACCESS]
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Jean-Quartier, C; Jeanquartier, F; Holzinger, A Open Data for Differential Network Analysis in Glioma.
Int J Mol Sci. 2020; 21(2): Doi: 10.3390/ijms21020547 [OPEN ACCESS]
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Muster, V; Gary, T Incidence, Therapy, and Bleeding Risk-Cancer- Associated Thrombosis in Patients with Glioblastoma.
Cancers (Basel). 2020; 12(6): Doi: 10.3390/cancers12061354 [OPEN ACCESS]
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Roetzer, T; Furtner, J; Gesperger, J; Seebrecht, L; Bandke, D; Brada, M; Brandner-Kokalj, T; Grams, A; Haybaeck, J; Kitzwoegerer, M; Leber, SL; Marhold, F; Moser, P; Sherif, C; Trenkler, J; Unterluggauer, J; Weis, S; Wuertz, F; Hainfellner, JA; Langs, G; Nenning, KH; Woehrer, A Sex-Specific Differences in Primary CNS Lymphoma.
Cancers (Basel). 2020; 12(6): Doi: 10.3390/cancers12061593 [OPEN ACCESS]
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Waldherr, L; Tiffner, A; Mishra, D; Sallinger, M; Schober, R; Frischauf, I; Schmidt, T; Handl, V; Sagmeister, P; Köckinger, M; Derler, I; Üçal, M; Bonhenry, D; Patz, S; Schindl, R Blockage of Store-Operated Ca2+ Influx by Synta66 is Mediated by Direct Inhibition of the Ca2+ Selective Orai1 Pore.
Cancers (Basel). 2020; 12(10): Doi: 10.3390/cancers12102876 [OPEN ACCESS]
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2019

Likar, R; Koestenberger, M; Stultschnig, M; Nahler, G Concomitant Treatment of Malignant Brain Tumours With CBD - A Case Series and Review of the Literature.
Anticancer Res. 2019; 39(10):5797-5801 Doi: 10.21873/anticanres.13783
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Lindner, L; Narnhofer, D; Weber, M; Gsaxner, C; Kolodziej, M; Egger, J Using Synthetic Training Data for Deep Learning-Based GBM Segmentation.
Annu Int Conf IEEE Eng Med Biol Soc. 2019; 2019(4):6724-6729 Doi: 10.1109/EMBC.2019.8856297
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2018

Buchroithner, J; Erhart, F; Pichler, J; Widhalm, G; Preusser, M; Stockhammer, G; Nowosielski, M; Iglseder, S; Freyschlag, CF; Oberndorfer, S; Bordihn, K; von Campe, G; Hoffermann, M; Ruckser, R; Rössler, K; Spiegl-Kreinecker, S; Fischer, MB; Czech, T; Visus, C; Krumpl, G; Felzmann, T; Marosi, C Audencel Immunotherapy Based on Dendritic Cells Has No Effect on Overall and Progression-Free Survival in Newly Diagnosed Glioblastoma: A Phase II Randomized Trial.
Cancers (Basel). 2018; 10(10): Doi: 10.3390/cancers10100372 [OPEN ACCESS]
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Kiesel, B; Mischkulnig, M; Woehrer, A; Martinez-Moreno, M; Millesi, M; Mallouhi, A; Czech, T; Preusser, M; Hainfellner, JA; Wolfsberger, S; Knosp, E; Widhalm, G Systematic histopathological analysis of different 5-aminolevulinic acid-induced fluorescence levels in newly diagnosed glioblastomas.
J Neurosurg. 2018; 129(2):341-353 Doi: 10.3171/2017.4.JNS162991
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Klughammer, J; Kiesel, B; Roetzer, T; Fortelny, N; Nemc, A; Nenning, KH; Furtner, J; Sheffield, NC; Datlinger, P; Peter, N; Nowosielski, M; Augustin, M; Mischkulnig, M; Ströbel, T; Alpar, D; Ergüner, B; Senekowitsch, M; Moser, P; Freyschlag, CF; Kerschbaumer, J; Thomé, C; Grams, AE; Stockhammer, G; Kitzwoegerer, M; Oberndorfer, S; Marhold, F; Weis, S; Trenkler, J; Buchroithner, J; Pichler, J; Haybaeck, J; Krassnig, S; Mahdy Ali, K; von Campe, G; Payer, F; Sherif, C; Preiser, J; Hauser, T; Winkler, PA; Kleindienst, W; Würtz, F; Brandner-Kokalj, T; Stultschnig, M; Schweiger, S; Dieckmann, K; Preusser, M; Langs, G; Baumann, B; Knosp, E; Widhalm, G; Marosi, C; Hainfellner, JA; Woehrer, A; Bock, C The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space.
Nat Med. 2018; 24(10):1611-1624 Doi: 10.1038/s41591-018-0156-x [OPEN ACCESS]
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Presser, A; Lainer, G; Kretschmer, N; Schuehly, W; Saf, R; Kaiser, M; Kalt, MM Synthesis of Jacaranone-Derived Nitrogenous Cyclohexadienones and Their Antiproliferative and Antiprotozoal Activities.
Molecules. 2018; 23(11): Doi: 10.3390/molecules23112902 [OPEN ACCESS]
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2017

Asslaber, M; Schauer, S; Gogg-Kamerer, M; Bernhart, E; Quehenberger, F; Haybaeck, J Native Oligodendrocytes in Astrocytomas Might Inhibit Tumor Proliferation by WIF1 Expression.
J Neuropathol Exp Neurol. 2017; 76(1):16-26 Doi: 10.1093/jnen/nlw098 [OPEN ACCESS]
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Nass, N; Walter, S; Jechorek, D; Weissenborn, C; Ignatov, A; Haybaeck, J; Sel, S; Kalinski, T High neuronatin (NNAT) expression is associated with poor outcome in breast cancer.
Virchows Arch. 2017; 471(1): 23-30. Doi: 10.1007/s00428-017-2154-7
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Riedl, J; Preusser, M; Nazari, PM; Posch, F; Panzer, S; Marosi, C; Birner, P; Thaler, J; Brostjan, C; Lötsch, D; Berger, W; Hainfellner, JA; Pabinger, I; Ay, C Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism.
Blood. 2017; 129(13):1831-1839 Doi: 10.1182/blood-2016-06-720714 [OPEN ACCESS]
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2016

Becker, J; Jehna, M; Larsen, N; Synowitz, M; Hartwigsen, G Glioblastoma in hemihydranencephaly: preoperative and postoperative language ability of the right hemisphere.
Acta Neurochir (Wien). 2016; 158(7):1317-1323 Doi: 10.1007/s00701-016-2825-1 (- Case Report)
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Brunner, TB The rationale of combined radiotherapy and chemotherapy - Joint action of Castor and Pollux.
Best Pract Res Clin Gastroenterol. 2016; 30(4):515-28 Doi: 10.1016/j.bpg.2016.07.002
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2015

Bernhart, E; Damm, S; Wintersperger, A; Nusshold, C; Brunner, AM; Plastira, I; Rechberger, G; Reicher, H; Wadsack, C; Zimmer, A; Malle, E; Sattler, W Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells.
Biochem Pharmacol. 2015; 96(2): 119-130. Doi: 10.1016/j.bcp.2015.05.007 [OPEN ACCESS]
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Hoffermann, M; Bruckmann, L; Kariem Mahdy, A; Asslaber, M; Payer, F; von Campe, G Treatment results and outcome in elderly patients with glioblastoma multiforme--a retrospective single institution analysis.
Clin Neurol Neurosurg. 2015; 128(2):60-69 Doi: 10.1016/j.clineuro.2014.11.006
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Karremann, M; Hoffmann, M; Benesch, M; Kwiecien, R; von Bueren, AO; Kramm, CM Secondary Solid Malignancies After High-Grade Glioma Treatment in Pediatric Patients.
Pediatr Hematol Oncol. 2015; 32(7):467-473 Doi: 10.3109/08880018.2015.1050615
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Nischwitz, SP; Bauer, J; Welzel, T; Rief, H; Jäkel, O; Haberer, T; Frey, K; Debus, J; Parodi, K; Combs, SE; Rieken, S Clinical implementation and range evaluation of in vivo PET dosimetry for particle irradiation in patients with primary glioma.
Radiother Oncol. 2015; 115(2): 179-185. Doi: 10.1016/j.radonc.2015.03.022
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Riedl, S; Leber, R; Rinner, B; Schaider, H; Lohner, K; Zweytick, D Human lactoferricin derived di-peptides deploying loop structures induce apoptosis specifically in cancer cells through targeting membranous phosphatidylserine.
Biochim Biophys Acta. 2015; 1848(11 Pt A):2918-2931 Doi: 10.1016/j.bbamem.2015.07.018 [OPEN ACCESS]
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Zhao, Q; Kretschmer, N; Bauer, R; Efferth, T Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib.
Int J Cancer. 2015; 137(6):1446-1456 Doi: 10.1002/ijc.29483 [OPEN ACCESS]
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Zuckermann, M; Hovestadt, V; Knobbe-Thomsen, CB; Zapatka, M; Northcott, PA; Schramm, K; Belic, J; Jones, DT; Tschida, B; Moriarity, B; Largaespada, D; Roussel, MF; Korshunov, A; Reifenberger, G; Pfister, SM; Lichter, P; Kawauchi, D; Gronych, J Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling.
Nat Commun. 2015; 6(3):7391-7391 Doi: 10.1038/ncomms8391 [OPEN ACCESS]
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2014

Bernaskova, M; Kretschmer, N; Schuehly, W; Huefner, A; Weis, R; Bauer, R Synthesis of tetrahydrohonokiol derivates and their evaluation for cytotoxic activity against CCRF-CEM leukemia, U251 glioblastoma and HCT-116 colon cancer cells.
Molecules. 2014; 19(1):1223-1237 Doi: 10.3390/molecules19011223 [OPEN ACCESS]
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Bernhart, E; Damm, S; Heffeter, P; Wintersperger, A; Asslaber, M; Frank, S; Hammer, A; Strohmaier, H; DeVaney, T; Mrfka, M; Eder, H; Windpassinger, C; Ireson, CR; Mischel, PS; Berger, W; Sattler, W Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.
Neuro Oncol. 2014; 16(7):933-945 Doi: 10.1093/neuonc/not303 [OPEN ACCESS]
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Buchroithner, J; Pichler, J; Marosi, C; Widhalm, G; Seiz-Rosenhagen, M; Novosielski, M; Oberndorfer, S; Ruckser, R; Rossler, K; Azizi, A; von Campe, G; Bordihn, K; Felzmann, T Vascular endothelia growth factor targeted therapy may improve the effect of dendritic cell-based cancer immune therapy
INT J CLIN PHARM TH. 2014; 52(1):76-77.-Extended Abstract, CESAR Annual Meeting; JUN 27-29, 2013; Tübingen, GERMANY. Doi: 10.5414/CPXCES13EA02 [Oral Communication]
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Furtner, J; Schöpf, V; Preusser, M; Asenbaum, U; Woitek, R; Wöhrer, A; Hainfellner, JA; Wolfsberger, S; Prayer, D Non-invasive assessment of intratumoral vascularity using arterial spin labeling: A comparison to susceptibility-weighted imaging for the differentiation of primary cerebral lymphoma and glioblastoma.
Eur J Radiol. 2014; 83(5):806-10 Doi: 10.1016/j.ejrad.2014.01.017
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Galasso, S; Pacifico, S; Kretschmer, N; Pan, SP; Marciano, S; Piccolella, S; Monaco, P; Bauer, R Influence of seasonal variation on Thymus longicaulis C. Presl chemical composition and its antioxidant and anti-inflammatory properties.
Phytochemistry. 2014; 107(6):80-90 Doi: 10.1016/j.phytochem.2014.08.015
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Hutterer, M; Nowosielski, M; Haybaeck, J; Embacher, S; Stockhammer, F; Gotwald, T; Holzner, B; Capper, D; Preusser, M; Marosi, C; Oberndorfer, S; Moik, M; Buchroithner, J; Seiz, M; Tuettenberg, J; Herrlinger, U; Wick, A; Vajkoczy, P; Stockhammer, G A single-arm phase II Austrian/German multicenter trial on continuous daily sunitinib in primary glioblastoma at first recurrence (SURGE 01-07).
Neuro Oncol. 2014; 16(1):92-102 Doi: 10.1093/neuonc/not161 [OPEN ACCESS]
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Müller, C; Holtschmidt, J; Auer, M; Heitzer, E; Lamszus, K; Schulte, A; Matschke, J; Langer-Freitag, S; Gasch, C; Stoupiec, M; Mauermann, O; Peine, S; Glatzel, M; Speicher, MR; Geigl, JB; Westphal, M; Pantel, K; Riethdorf, S Hematogenous dissemination of glioblastoma multiforme.
Sci Transl Med. 2014; 6(247):247ra101-247ra101 Doi: 10.1126/scitranslmed.3009095 [OPEN ACCESS]
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Schweneker, K; Clemm, C; Brügel, M; Souvatzoglou, M; Hermisson, M; Schmidt-Graf, F; Zimmer, C; Peschel, C; Jost, PJ Effective long-term treatment with bevacizumab for relapsed glioblastoma: case report and review of the literature.
Exp Hematol Oncol. 2014; 3(16):29-29 Doi: 10.1186/2162-3619-3-29 (- Case Report) [OPEN ACCESS]
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2013

Bernhart, E; Damm, S; Wintersperger, A; DeVaney, T; Zimmer, A; Raynham, T; Ireson, C; Sattler, W Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro.
Exp Cell Res. 2013; 319(13):2037-2048 Doi: 10.1016/j.yexcr.2013.03.029 [OPEN ACCESS]
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Egger, J; Kapur, T; Fedorov, A; Pieper, S; Miller, JV; Veeraraghavan, H; Freisleben, B; Golby, AJ; Nimsky, C; Kikinis, R GBM volumetry using the 3D Slicer medical image computing platform.
Sci Rep. 2013; 3(10):1364-1364 Doi: 10.1038/srep01364 [OPEN ACCESS]
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Eibinger, G; Fauler, G; Bernhart, E; Frank, S; Hammer, A; Wintersperger, A; Eder, H; Heinemann, A; Mischel, PS; Malle, E; Sattler, W On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment.
Exp Cell Res. 2013; 319(12):1828-1838 Doi: 10.1016/j.yexcr.2013.03.025 [OPEN ACCESS]
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Grah, JJ; Katalinic, D; Stern-Padovan, R; Paladino, J; Santek, F; Juretic, A; Zarkovic, K; Plestina, S; Supe, M Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy.
World J Surg Oncol. 2013; 11(1):55-55 Doi: 10.1186/1477-7819-11-55 (- Case Report) [OPEN ACCESS]
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Jahnke, HG; Heimann, A; Azendorf, R; Mpoukouvalas, K; Kempski, O; Robitzki, AA; Charalampaki, P Impedance spectroscopy--an outstanding method for label-free and real-time discrimination between brain and tumor tissue in vivo.
Biosens Bioelectron. 2013; 46(7):8-14 Doi: 10.1016/j.bios.2013.02.013
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Löhr, M; Molcanyi, M; Poggenborg, J; Spuentrup, E; Runge, M; Röhn, G; Härtig, W; Hescheler, J; Hampl, JA Intracerebral administration of heat-inactivated Staphylococcus epidermidis enhances oncolysis and prolongs survival in a 9L orthotopic gliosarcoma model.
Cell Physiol Biochem. 2013; 31(4-5): 614-624. Doi: 10.1159/000350081 [OPEN ACCESS]
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Rangger, C; Helbok, A; Sosabowski, J; Kremser, C; Koehler, G; Prassl, R; Andreae, F; Virgolini, IJ; von Guggenberg, E; Decristoforo, C Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles.
Int J Nanomedicine. 2013; 8(6):4659-4671 Doi: 10.2147/IJN.S51927 [OPEN ACCESS]
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