Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: GENE EXPRESSION REGULATION, NEOPLASTIC - DRUG EFFECTS , . Treffer: 39

2018

Fuchs, R; Stracke, A; Holzmann, V; Luschin-Ebengreuth, G; Meier-Allard, N; Ebner, N; Lassacher, TM; Absenger-Novak, M; Fröhlich, E; Schittmayer, M; Cano Crespo, S; Palacin, M; Rinner, B; Birner-Gruenberger, R Prazosin induced lysosomal tubulation interferes with cytokinesis and the endocytic sorting of the tumour antigen CD98hc.
Biochim Biophys Acta Mol Cell Res. 2018; 1865(9):1211-1229 [OPEN ACCESS]
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2017

Cuppens, T; Annibali, D; Coosemans, A; Trovik, J; Ter Haar, N; Colas, E; Garcia-Jimenez, A; Van de Vijver, K; Kruitwagen, RP; Brinkhuis, M; Zikan, M; Dundr, P; Huvila, J; Carpén, O; Haybaeck, J; Moinfar, F; Salvesen, HB; Stukan, M; Mestdagh, C; Zweemer, RP; Massuger, LF; Mallmann, MR; Wardelmann, E; Mints, M; Verbist, G; Thomas, D; Gommé, E; Hermans, E; Moerman, P; Bosse, T; Amant, F Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Clin Cancer Res. 2017; 23(5):1274-1285 [OPEN ACCESS]
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Mairinger, FD; Vollbrecht, C; Flom, E; Christoph, DC; Schmid, KW; Kollmeier, J; Popper, HH; Mairinger, T; Walter, RFH Folic acid phenotype (FAP) is a superior biomarker predicting response to pemetrexed-based chemotherapy in malignant pleural mesothelioma.
Oncotarget. 2017; 8(23):37502-37510 [OPEN ACCESS]
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Pfanzagl, B; Mechtcheriakova, D; Meshcheryakova, A; Aberle, SW; Pfragner, R; Jensen-Jarolim, E Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R.
Sci Rep. 2017; 7(1):1313-1313 [OPEN ACCESS]
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Račkauskas, R; Zhou, D; Ūselis, S; Strupas, K; Herr, I; Schemmer, P Sulforaphane sensitizes human cholangiocarcinoma to cisplatin via the downregulation of anti-apoptotic proteins.
Oncol Rep. 2017; 37(6):3660-3666 [OPEN ACCESS]
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Schanza, LM; Seles, M; Stotz, M; Fosselteder, J; Hutterer, GC; Pichler, M; Stiegelbauer, V MicroRNAs Associated with Von Hippel-Lindau Pathway in Renal Cell Carcinoma: A Comprehensive Review.
Int J Mol Sci. 2017; 18(11): [OPEN ACCESS]
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2016

Arriga, R; Caratelli, S; Coppola, A; Spagnoli, GC; Venditti, A; Amadori, S; Lanzilli, G; Lauro, D; Palomba, P; Sconocchia, T; Del Principe, MI; Maurillo, L; Buccisano, F; Capuani, B; Ferrone, S; Sconocchia, G Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage.
Oncotarget. 2016; 7(2): 2070-2079. [OPEN ACCESS]
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Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591
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Fan, P; Zhang, Y; Liu, L; Zhao, Z; Yin, Y; Xiao, X; Bauer, N; Gladkich, J; Mattern, J; Gao, C; Schemmer, P; Gross, W; Herr, I Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.
Cell Death Dis. 2016; 7(6):e2246-e2246 [OPEN ACCESS]
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Jagadeeshan, S; Subramanian, A; Tentu, S; Beesetti, S; Singhal, M; Raghavan, S; Surabhi, RP; Mavuluri, J; Bhoopalan, H; Biswal, J; Pitani, RS; Chidambaram, S; Sundaram, S; Malathi, R; Jeyaraman, J; Nair, AS; Venkatraman, G; Rayala, SK P21-activated kinase 1 (Pak1) signaling influences therapeutic outcome in pancreatic cancer.
Ann Oncol. 2016; 27(8):1546-1556
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Mayr, C; Wagner, A; Loeffelberger, M; Bruckner, D; Jakab, M; Berr, F; Di Fazio, P; Ocker, M; Neureiter, D; Pichler, M; Kiesslich, T The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells.
Oncotarget. 2016; 7(1):745-758 [OPEN ACCESS]
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2015

Dehghan Esmatabadi, MJ; Farhangi, B; Safari, Z; Kazerooni, H; Shirzad, H; Zolghadr, F; Sadeghizadeh, M Dendrosomal curcumin inhibits metastatic potential of human SW480 colon cancer cells through Down-regulation of Claudin1, Zeb1 and Hef1-1 gene expression.
Asian Pac J Cancer Prev. 2015; 16(6):2473-2481 [OPEN ACCESS]
PubMed

 

Lohberger, B; Leithner, A; Stuendl, N; Kaltenegger, H; Kullich, W; Steinecker-Frohnwieser, B Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation.
BMC Cancer. 2015; 15(3):891-891 [OPEN ACCESS]
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Mayr, C; Wagner, A; Stoecklinger, A; Jakab, M; Illig, R; Berr, F; Pichler, M; Di Fazio, P; Ocker, M; Neureiter, D; Kiesslich, T 3-Deazaneplanocin A May Directly Target Putative Cancer Stem Cells in Biliary Tract Cancer.
Anticancer Res. 2015; 35(9):4697-4705
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Wenzl, K; Troppan, K; Neumeister, P; Deutsch, AJ The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.
Curr Drug Targets. 2015; 16(1):38-46
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2014

Adam, C; Baeurle, A; Brodsky, JL; Wipf, P; Schrama, D; Becker, JC; Houben, R The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.
PLoS One. 2014; 9(4):e92041-e92041 [OPEN ACCESS]
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Fröhlich, E; Wahl, R The current role of targeted therapies to induce radioiodine uptake in thyroid cancer.
CANCER TREAT REV. 2014; 40(5): 665-674.
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Heiduschka, G; Grah, A; Oberndorfer, F; Seemann, R; Kranz, A; Kornek, G; Wrba, F; Thurnher, D; Selzer, E Significance of p16 expression in head and neck cancer patients treated with radiotherapy and cetuximab.
Strahlenther Onkol. 2014; 190(9):832-838
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Ress, AL; Stiegelbauer, V; Schwarzenbacher, D; Deutsch, A; Perakis, S; Ling, H; Ivan, C; Calin, GA; Rinner, B; Gerger, A; Pichler, M Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer.
Oncotarget. 2014; 5(18):8492-8502 [OPEN ACCESS]
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Singer, CF; Bennink, HJ; Natter, C; Steurer, S; Rudas, M; Moinfar, F; Appels, N; Visser, M; Kubista, E Antiestrogenic effects of the fetal estrogen estetrol in women with estrogen-receptor positive early breast cancer.
Carcinogenesis. 2014; 35(11):2447-2451 [OPEN ACCESS]
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Stiegelbauer, V; Perakis, S; Deutsch, A; Ling, H; Gerger, A; Pichler, M MicroRNAs as novel predictive biomarkers and therapeutic targets in colorectal cancer.
World J Gastroenterol. 2014; 20(33):11727-11735 [OPEN ACCESS]
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Wagner, A; Mayr, C; Bach, D; Illig, R; Plaetzer, K; Berr, F; Pichler, M; Neureiter, D; Kiesslich, T MicroRNAs associated with the efficacy of photodynamic therapy in biliary tract cancer cell lines.
Int J Mol Sci. 2014; 15(11):20134-20157 [OPEN ACCESS]
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Walter, I; Wolfesberger, B; Miller, I; Mair, G; Burger, S; Gallè, B; Steinborn, R Human osteosarcoma cells respond to sorafenib chemotherapy by downregulation of the tumor progression factors S100A4, CXCR4 and the oncogene FOS.
Oncol Rep. 2014; 31(3):1147-1156 [OPEN ACCESS]
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2013

Bernhart, E; Damm, S; Wintersperger, A; DeVaney, T; Zimmer, A; Raynham, T; Ireson, C; Sattler, W Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro.
Exp Cell Res. 2013; 319(13):2037-2048 [OPEN ACCESS]
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Olaussen, KA; Adam, J; Vanhecke, E; Vielh, P; Pirker, R; Friboulet, L; Popper, H; Robin, A; Commo, F; Thomale, J; Kayitalire, L; Filipits, M; Le Chevalier, T; André, F; Brambilla, E; Soria, JC PARP1 impact on DNA repair of platinum adducts: preclinical and clinical read-outs.
Lung Cancer. 2013; 80(2):216-222 [OPEN ACCESS]
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Sbiera, S; Kroiss, M; Thamm, T; Beyer, M; Majidi, F; Kuehner, D; Wobser, M; Becker, JC; Adam, P; Ronchi, C; Allolio, B; Fassnacht, M; Survivin in Adrenocortical Tumors Pathophysiological Implications and Therapeutic Potential.
HORMONE METAB RES. 2013; 45(2): 137-146. [OPEN ACCESS]
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2012

Bujnicki, T; Wilczek, C; Schomburg, C; Feldmann, F; Schlenke, P; Müller-Tidow, C; Schmidt, TJ; Klempnauer, KH Inhibition of Myb-dependent gene expression by the sesquiterpene lactone mexicanin-I.
Leukemia. 2012; 26(4): 615-622.
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Deutsch, AJ; Angerer, H; Fuchs, TE; Neumeister, P The nuclear orphan receptors NR4A as therapeutic target in cancer therapy.
Anticancer Agents Med Chem. 2012; 12(9):1001-1014
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Kalhan, A; Gharibi, B; Vazquez, M; Jasani, B; Neal, J; Kidd, M; Modlin, IM; Pfragner, R; Rees, DA; Ham, J Adenosine A2A and A2B receptor expression in neuroendocrine tumours: potential targets for therapy.
Purinergic Signal. 2012; 8(2):265-274 [OPEN ACCESS]
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Laimer, D; Dolznig, H; Kollmann, K; Vesely, PW; Schlederer, M; Merkel, O; Schiefer, AI; Hassler, MR; Heider, S; Amenitsch, L; Thallinger, C; Staber, PB; Simonitsch-Klupp, I; Artaker, M; Lagger, S; Turner, SD; Pileri, S; Piccaluga, PP; Valent, P; Messana, K; Landra, I; Weichhart, T; Knapp, S; Shehata, M; Todaro, M; Sexl, V; Höfler, G; Piva, R; Medico, E; Ruggeri, BA; Cheng, M; Eferl, R; Egger, G; Penninger, JM; Jaeger, U; Moriggl, R; Inghirami, G; Kenner, L PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Nat Med. 2012; 18(11):1699-1704 [OPEN ACCESS]
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Shirsath, NP; Manohar, SM; Joshi, KS P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines.
Mol Cancer. 2012; 11:77-77 [OPEN ACCESS]
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Wachter, J; Neureiter, D; Alinger, B; Pichler, M; Fuereder, J; Oberdanner, C; Di Fazio, P; Ocker, M; Berr, F; Kiesslich, T Influence of five potential anticancer drugs on wnt pathway and cell survival in human biliary tract cancer cells.
Int J Biol Sci. 2012; 8(1):15-29 [OPEN ACCESS]
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Windischhofer, W; Huber, E; Rossmann, C; Semlitsch, M; Kitz, K; Rauh, A; Devaney, T; Leis, HJ; Malle, E LPA-induced suppression of periostin in human osteosarcoma cells is mediated by the LPA(1)/Egr-1 axis.
Biochimie. 2012; 94(9):1997-2005 [OPEN ACCESS]
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2011

Fröhlich, E; Engel, E; Wahl, R Decrease in dipeptidyl peptidase IV activity is linked to the efficacy of differentiating compounds in follicular thyroid carcinoma cell lines.
HORMONE METAB RES. 2011; 43(5): 364-366. [OPEN ACCESS]
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2010

Hoffmann, K; Franz, C; Xiao, Z; Mohr, E; Serba, S; Büchler, MW; Schemmer, P Sorafenib modulates the gene expression of multi-drug resistance mediating ATP-binding cassette proteins in experimental hepatocellular carcinoma.
Anticancer Res. 2010; 30(11):4503-4508
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Prager, GW; Lackner, EM; Krauth, MT; Unseld, M; Poettler, M; Laffer, S; Cerny-Reiterer, S; Lamm, W; Kornek, GV; Binder, BR; Zielinski, CC; Valent, P Targeting of VEGF-dependent transendothelial migration of cancer cells by bevacizumab.
Mol Oncol. 2010; 4(2): 150-160. [OPEN ACCESS]
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2009

Fröhlich, E; Fink, I; Wahl, R Is transketolase like 1 a target for the treatment of differentiated thyroid carcinoma? A study on thyroid cancer cell lines.
Invest New Drugs. 2009; 27(4): 297-303.
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Kallifatidis, G; Rausch, V; Baumann, B; Apel, A; Beckermann, BM; Groth, A; Mattern, J; Li, Z; Kolb, A; Moldenhauer, G; Altevogt, P; Wirth, T; Werner, J; Schemmer, P; Büchler, MW; Salnikov, AV; Herr, I Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling.
Gut. 2009; 58(7):949-963
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2007

Kidd, M; Modlin, IM; Pfragner, R; Eick, GN; Champaneria, MC; Chan, AK; Camp, RL; Mane, SM Small bowel carcinoid (enterochromaffin cell) neoplasia exhibits transforming growth factor-beta1-mediated regulatory abnormalities including up-regulation of C-Myc and MTA1.
CANCER. 2007; 109(12): 2420-2431. [OPEN ACCESS]
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