Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: GENE EXPRESSION REGULATION, NEOPLASTIC - , . Treffer: 146

2019

Golob-Schwarzl, N; Wodlej, C; Kleinegger, F; Gogg-Kamerer, M; Birkl-Toeglhofer, AM; Petzold, J; Aigelsreiter, A; Thalhammer, M; Park, YN; Haybaeck, J Eukaryotic translation initiation factor 6 overexpression plays a major role in the translational control of gallbladder cancer.
J Cancer Res Clin Oncol. 2019; 145(11): 2699-2711. [OPEN ACCESS]
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2018

Alunni-Fabbroni, M; Majunke, L; Trapp, EK; Tzschaschel, M; Mahner, S; Fasching, PA; Fehm, T; Schneeweiss, A; Beck, T; Lorenz, R; Friedl, TWP; Janni, W; Rack, B; SUCCESS Study Group Whole blood microRNAs as potential biomarkers in post-operative early breast cancer patients.
BMC Cancer. 2018; 18(1):141-141 [OPEN ACCESS]
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Tsibulak, I; Wieser, V; Degasper, C; Shivalingaiah, G; Wenzel, S; Sprung, S; Lax, SF; Marth, C; Fiegl, H; Zeimet, AG BRCA1 and BRCA2 mRNA-expression prove to be of clinical impact in ovarian cancer.
Br J Cancer. 2018; 119(6):683-692 [OPEN ACCESS]
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2017

Asslaber, M; Schauer, S; Gogg-Kamerer, M; Bernhart, E; Quehenberger, F; Haybaeck, J Native Oligodendrocytes in Astrocytomas Might Inhibit Tumor Proliferation by WIF1 Expression.
J Neuropathol Exp Neurol. 2017; 76(1):16-26 [OPEN ACCESS]
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Dengler, M; Staufer, K; Huber, H; Stauber, R; Bantel, H; Weiss, KH; Starlinger, P; Pock, H; Klöters-Plachky, P; Gotthardt, DN; Rauch, P; Lackner, C; Stift, J; Brostjan, C; Gruenberger, T; Kumada, T; Toyoda, H; Tada, T; Weiss, TS; Trauner, M; Mikulits, W Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis.
Oncotarget. 2017; 8(28):46234-46248 [OPEN ACCESS]
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Deutsch, AJA; Rinner, B; Pichler, M; Prochazka, K; Pansy, K; Bischof, M; Fechter, K; Hatzl, S; Feichtinger, J; Wenzl, K; Frisch, MT; Stiegelbauer, V; Prokesch, A; Krogsdam, A; Sill, H; Thallinger, GG; Greinix, HT; Wang, C; Beham-Schmid, C; Neumeister, P NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.
Cancer Res. 2017; 77(9):2375-2386 [OPEN ACCESS]
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Goblirsch, M; Richtig, G; Slaby, O; Berindan-Neagoe, I; Gerger, A; Pichler, M MicroRNAs as a tool to aid stratification of colorectal cancer patients and to guide therapy.
Pharmacogenomics. 2017; 18(10):1027-1038
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González-Vela, MDC; Curiel-Olmo, S; Derdak, S; Beltran, S; Santibañez, M; Martínez, N; Castillo-Trujillo, A; Gut, M; Sánchez-Pacheco, R; Almaraz, C; Cereceda, L; Llombart, B; Agraz-Doblas, A; Revert-Arce, J; López Guerrero, JA; Mollejo, M; Marrón, PI; Ortiz-Romero, P; Fernandez-Cuesta, L; Varela, I; Gut, I; Cerroni, L; Piris, MÁ; Vaqué, JP Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas.
J Invest Dermatol. 2017; 137(1):197-206 [OPEN ACCESS]
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Görtz, M; Galli, U; Longerich, T; Zöller, M; Erb, U; Schemmer, P De novo synthesis of C4.4A in hepatocellular carcinoma promotes migration and invasion of tumor cells.
Oncol Rep. 2017; 38(5):2697-2704 [OPEN ACCESS]
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Hlavaty, J; Wolfesberger, B; Hauck, M; Obermayer-Pietsch, B; Fuchs-Baumgartinger, A; Miller, I; Walter, I Ezrin and moesin expression in canine and feline osteosarcoma.
Histol Histopathol. 2017; 32(8):805-816
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Jäger, D; Barth, TFE; Brüderlein, S; Scheuerle, A; Rinner, B; von Witzleben, A; Lechel, A; Meyer, P; Mayer-Steinacker, R; Baer, AV; Schultheiss, M; Wirtz, CR; Möller, P; Mellert, K HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas.
Sci Rep. 2017; 7(1):2032-2032 [OPEN ACCESS]
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Rashed, MH; Kanlikilicer, P; Rodriguez-Aguayo, C; Pichler, M; Bayraktar, R; Bayraktar, E; Ivan, C; Filant, J; Silva, A; Aslan, B; Denizli, M; Mitra, R; Ozpolat, B; Calin, GA; Sood, AK; Abd-Ellah, MF; Helal, GK; Berestein, GL Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.
Oncotarget. 2017; 8(12):20145-20164 [OPEN ACCESS]
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Richtig, G; Aigelsreiter, A; Schwarzenbacher, D; Ress, AL; Adiprasito, JB; Stiegelbauer, V; Hoefler, G; Schauer, S; Kiesslich, T; Kornprat, P; Winder, T; Eisner, F; Gerger, A; Stoeger, H; Stauber, R; Lackner, C; Pichler, M SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types.
PLoS One. 2017; 12(11):e0187814-e0187814 [OPEN ACCESS]
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Richtig, G; Ehall, B; Richtig, E; Aigelsreiter, A; Gutschner, T; Pichler, M Function and Clinical Implications of Long Non-Coding RNAs in Melanoma.
Int J Mol Sci. 2017; 18(4): [OPEN ACCESS]
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Rigoutsos, I; Lee, SK; Nam, SY; Anfossi, S; Pasculli, B; Pichler, M; Jing, Y; Rodriguez-Aguayo, C; Telonis, AG; Rossi, S; Ivan, C; Catela Ivkovic, T; Fabris, L; Clark, PM; Ling, H; Shimizu, M; Redis, RS; Shah, MY; Zhang, X; Okugawa, Y; Jung, EJ; Tsirigos, A; Huang, L; Ferdin, J; Gafà, R; Spizzo, R; Nicoloso, MS; Paranjape, AN; Shariati, M; Tiron, A; Yeh, JJ; Teruel-Montoya, R; Xiao, L; Melo, SA; Menter, D; Jiang, ZQ; Flores, ER; Negrini, M; Goel, A; Bar-Eli, M; Mani, SA; Liu, CG; Lopez-Berestein, G; Berindan-Neagoe, I; Esteller, M; Kopetz, S; Lanza, G; Calin, GA N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration.
Genome Biol. 2017; 18(1):98-98 [OPEN ACCESS]
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Schütte, M; Risch, T; Abdavi-Azar, N; Boehnke, K; Schumacher, D; Keil, M; Yildiriman, R; Jandrasits, C; Borodina, T; Amstislavskiy, V; Worth, CL; Schweiger, C; Liebs, S; Lange, M; Warnatz, HJ; Butcher, LM; Barrett, JE; Sultan, M; Wierling, C; Golob-Schwarzl, N; Lax, S; Uranitsch, S; Becker, M; Welte, Y; Regan, JL; Silvestrov, M; Kehler, I; Fusi, A; Kessler, T; Herwig, R; Landegren, U; Wienke, D; Nilsson, M; Velasco, JA; Garin-Chesa, P; Reinhard, C; Beck, S; Schäfer, R; Regenbrecht, CR; Henderson, D; Lange, B; Haybaeck, J; Keilholz, U; Hoffmann, J; Lehrach, H; Yaspo, ML Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Nat Commun. 2017; 8(2):14262-14262 [OPEN ACCESS]
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Sheffield, NC; Pierron, G; Klughammer, J; Datlinger, P; Schönegger, A; Schuster, M; Hadler, J; Surdez, D; Guillemot, D; Lapouble, E; Freneaux, P; Champigneulle, J; Bouvier, R; Walder, D; Ambros, IM; Hutter, C; Sorz, E; Amaral, AT; de Álava, E; Schallmoser, K; Strunk, D; Rinner, B; Liegl-Atzwanger, B; Huppertz, B; Leithner, A; de Pinieux, G; Terrier, P; Laurence, V; Michon, J; Ladenstein, R; Holter, W; Windhager, R; Dirksen, U; Ambros, PF; Delattre, O; Kovar, H; Bock, C; Tomazou, EM DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.
Nat Med. 2017; 23(3):386-395 [OPEN ACCESS]
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Shen, P; Pichler, M; Chen, M; Calin, GA; Ling, H To Wnt or Lose: The Missing Non-Coding Linc in Colorectal Cancer.
Int J Mol Sci. 2017; 18(9): [OPEN ACCESS]
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Smolle, MA; Bauernhofer, T; Pummer, K; Calin, GA; Pichler, M Current Insights into Long Non-Coding RNAs (LncRNAs) in Prostate Cancer.
Int J Mol Sci. 2017; 18(2): [OPEN ACCESS]
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Smolle, MA; Leithner, A; Posch, F; Szkandera, J; Liegl-Atzwanger, B; Pichler, M MicroRNAs in Different Histologies of Soft Tissue Sarcoma: A Comprehensive Review.
Int J Mol Sci. 2017; 18(9): [OPEN ACCESS]
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Trapp, EK; Majunke, L; Zill, B; Sommer, H; Andergassen, U; Koch, J; Harbeck, N; Mahner, S; Friedl, TWP; Janni, W; Rack, B; Alunni-Fabbroni, M LKB1 pro-oncogenic activity triggers cell survival in circulating tumor cells.
Mol Oncol. 2017; 11(11):1508-1526 [OPEN ACCESS]
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Wohlkoenig, C; Leithner, K; Olschewski, A; Olschewski, H; Hrzenjak, A TR3 is involved in hypoxia-induced apoptosis resistance in lung cancer cells downstream of HIF-1α.
Lung Cancer. 2017; 111(3):15-22
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2016

Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 [OPEN ACCESS]
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Barghash, A; Golob-Schwarzl, N; Helms, V; Haybaeck, J; Kessler, SM Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma.
Oncotarget. 2016; 7(31):49743-49750 [OPEN ACCESS]
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Cerk, S; Schwarzenbacher, D; Adiprasito, JB; Stotz, M; Hutterer, GC; Gerger, A; Ling, H; Calin, GA; Pichler, M Current Status of Long Non-Coding RNAs in Human Breast Cancer.
Int J Mol Sci. 2016; 17(9): [OPEN ACCESS]
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Fan, P; Liu, L; Yin, Y; Zhao, Z; Zhang, Y; Amponsah, PS; Xiao, X; Bauer, N; Abukiwan, A; Nwaeburu, CC; Gladkich, J; Gao, C; Schemmer, P; Gross, W; Herr, I MicroRNA-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer.
Cancer Lett. 2016; 373(1):130-137
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Harada, Y; Izumi, H; Noguchi, H; Kuma, A; Kawatsu, Y; Kimura, T; Kitada, S; Uramoto, H; Wang, KY; Sasaguri, Y; Hijioka, H; Miyawaki, A; Oya, R; Nakayama, T; Kohno, K; Yamada, S Strong expression of polypeptide N-acetylgalactosaminyltransferase 3 independently predicts shortened disease-free survival in patients with early stage oral squamous cell carcinoma.
Tumour Biol. 2016; 37(1):1357-1368 [OPEN ACCESS]
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Jeric, I; Maurer, G; Cavallo, AL; Raguz, J; Desideri, E; Tarkowski, B; Parrini, M; Fischer, I; Zatloukal, K; Baccarini, M A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nat Commun. 2016; 7(12):13781-13781 [OPEN ACCESS]
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Kammerer, S; Sokolowski, A; Hackl, H; Platzer, D; Jahn, SW; El-Heliebi, A; Schwarzenbacher, D; Stiegelbauer, V; Pichler, M; Rezania, S; Fiegl, H; Peintinger, F; Regitnig, P; Hoefler, G; Schreibmayer, W; Bauernhofer, T KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients.
Oncotarget. 2016; 7(51):84705-84717 [OPEN ACCESS]
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Leithner, K; Hirschmugl, B; Li, Y; Tang, B; Papp, R; Nagaraj, C; Stacher, E; Stiegler, P; Lindenmann, J; Olschewski, A; Olschewski, H; Hrzenjak, A TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers.
PLoS One. 2016; 11(6):e0157453-e0157453 [OPEN ACCESS]
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Ling, H; Krassnig, L; Bullock, MD; Pichler, M MicroRNAs in Testicular Cancer Diagnosis and Prognosis.
Urol Clin North Am. 2016; 43(1):127-134
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Ling, H; Pickard, K; Ivan, C; Isella, C; Ikuo, M; Mitter, R; Spizzo, R; Bullock, M; Braicu, C; Pileczki, V; Vincent, K; Pichler, M; Stiegelbauer, V; Hoefler, G; Almeida, MI; Hsiao, A; Zhang, X; Primrose, J; Packham, G; Liu, K; Bojja, K; Gafà, R; Xiao, L; Rossi, S; Song, JH; Vannini, I; Fanini, F; Kopetz, S; Zweidler-McKay, P; Wang, X; Ionescu, C; Irimie, A; Fabbri, M; Lanza, G; Hamilton, SR; Berindan-Neagoe, I; Medico, E; Mirnezami, A; Calin, GA; Nicoloso, MS The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.
Gut. 2016; 65(6):977-989 [OPEN ACCESS]
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Mayr, C; Beyreis, M; Wagner, A; Pichler, M; Neureiter, D; Kiesslich, T Deregulated MicroRNAs in Biliary Tract Cancer: Functional Targets and Potential Biomarkers.
Biomed Res Int. 2016; 2016(12):4805270-4805270 [OPEN ACCESS]
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Mlecnik, B; Bindea, G; Kirilovsky, A; Angell, HK; Obenauf, AC; Tosolini, M; Church, SE; Maby, P; Vasaturo, A; Angelova, M; Fredriksen, T; Mauger, S; Waldner, M; Berger, A; Speicher, MR; Pagès, F; Valge-Archer, V; Galon, J The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.
Sci Transl Med. 2016; 8(327):327ra26-327ra26
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Ohtsuka, M; Ling, H; Ivan, C; Pichler, M; Matsushita, D; Goblirsch, M; Stiegelbauer, V; Shigeyasu, K; Zhang, X; Chen, M; Vidhu, F; Bartholomeusz, GA; Toiyama, Y; Kusunoki, M; Doki, Y; Mori, M; Song, S; Gunther, JR; Krishnan, S; Slaby, O; Goel, A; Ajani, JA; Radovich, M; Calin, GA H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.
EBioMedicine. 2016; 13(3):113-124 [OPEN ACCESS]
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Pehserl, AM; Ress, AL; Stanzer, S; Resel, M; Karbiener, M; Stadelmeyer, E; Stiegelbauer, V; Gerger, A; Mayr, C; Scheideler, M; Hutterer, GC; Bauernhofer, T; Kiesslich, T; Pichler, M Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells.
Int J Mol Sci. 2016; 17(12): [OPEN ACCESS]
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Perakis, SO; Thomas, JE; Pichler, M Non-coding RNAs Enabling Prognostic Stratification and Prediction of Therapeutic Response in Colorectal Cancer Patients.
Adv Exp Med Biol. 2016; 937(4):183-204
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Rezania, S; Kammerer, S; Li, C; Steinecker-Frohnwieser, B; Gorischek, A; DeVaney, TT; Verheyen, S; Passegger, CA; Tabrizi-Wizsy, NG; Hackl, H; Platzer, D; Zarnani, AH; Malle, E; Jahn, SW; Bauernhofer, T; Schreibmayer, W Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.
BMC Cancer. 2016; 16(1):628-628 [OPEN ACCESS]
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Seles, M; Hutterer, GC; Kiesslich, T; Pummer, K; Berindan-Neagoe, I; Perakis, S; Schwarzenbacher, D; Stotz, M; Gerger, A; Pichler, M Current Insights into Long Non-Coding RNAs in Renal Cell Carcinoma.
Int J Mol Sci. 2016; 17(4):573-573 [OPEN ACCESS]
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2015

Bochis, OV; Irimie, A; Pichler, M; Berindan-Neagoe, I The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer.
J Gastrointestin Liver Dis. 2015; 24(2):225-234 [OPEN ACCESS]
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Cerny-Reiterer, S; Rabenhorst, A; Stefanzl, G; Herndlhofer, S; Hoermann, G; Müllauer, L; Baumgartner, S; Beham-Schmid, C; Sperr, WR; Mannhalter, C; Sill, H; Linkesch, W; Arock, M; Hartmann, K; Valent, P Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia.
Oncotarget. 2015; 6(5):3071-3084 [OPEN ACCESS]
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Crescenzo, R; Abate, F; Lasorsa, E; Tabbo', F; Gaudiano, M; Chiesa, N; Di Giacomo, F; Spaccarotella, E; Barbarossa, L; Ercole, E; Todaro, M; Boi, M; Acquaviva, A; Ficarra, E; Novero, D; Rinaldi, A; Tousseyn, T; Rosenwald, A; Kenner, L; Cerroni, L; Tzankov, A; Ponzoni, M; Paulli, M; Weisenburger, D; Chan, WC; Iqbal, J; Piris, MA; Zamo', A; Ciardullo, C; Rossi, D; Gaidano, G; Pileri, S; Tiacci, E; Falini, B; Shultz, LD; Mevellec, L; Vialard, JE; Piva, R; Bertoni, F; Rabadan, R; Inghirami, G; European T-Cell Lymphoma Study Group, T-Cell Project: Prospective Collection of Data in Patients with Peripheral T-Cell Lymphoma and the AIRC 5xMille Consortium “Genetics-Driven Targeted Management of Lymphoid Malignancies” Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.
Cancer Cell. 2015; 27(4):516-532 [OPEN ACCESS]
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Didiasova, M; Zakrzewicz, D; Magdolen, V; Nagaraj, C; Bálint, Z; Rohde, M; Preissner, KT; Wygrecka, M STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization.
J Biol Chem. 2015; 290(19):11983-11999 [OPEN ACCESS]
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Eisner, F; Pichler, M; Goletz, S; Stoeger, H; Samonigg, H A glyco-engineered anti-HER2 monoclonal antibody (TrasGEX) induces a long-lasting remission in a patient with HER2 overexpressing metastatic colorectal cancer after failure of all available treatment options.
J Clin Pathol. 2015; 68(12):1044-1046 (- Case Report) [OPEN ACCESS]
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Elgohary, N; Pellegrino, R; Neumann, O; Elzawahry, HM; Saber, MM; Zeeneldin, AA; Geffers, R; Ehemann, V; Schemmer, P; Schirmacher, P; Longerich, T Protumorigenic role of Timeless in hepatocellular carcinoma.
Int J Oncol. 2015; 46(2):597-606 [OPEN ACCESS]
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Jagadeeshan, S; Krishnamoorthy, YR; Singhal, M; Subramanian, A; Mavuluri, J; Lakshmi, A; Roshini, A; Baskar, G; Ravi, M; Joseph, LD; Sadasivan, K; Krishnan, A; Nair, AS; Venkatraman, G; Rayala, SK Transcriptional regulation of fibronectin by p21-activated kinase-1 modulates pancreatic tumorigenesis.
Oncogene. 2015; 34(4):455-464
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Laszlo, V; Hoda, MA; Garay, T; Pirker, C; Ghanim, B; Klikovits, T; Dong, YW; Rozsas, A; Kenessey, I; Szirtes, I; Grusch, M; Jakopovic, M; Samarzija, M; Brcic, L; Kern, I; Rozman, A; Popper, H; Zöchbauer-Müller, S; Heller, G; Altenberger, C; Ziegler, B; Klepetko, W; Berger, W; Dome, B; Hegedus, B Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.
J Pathol. 2015; 237(2):203-214
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Lin, AP; Abbas, S; Kim, SW; Ortega, M; Bouamar, H; Escobedo, Y; Varadarajan, P; Qin, Y; Sudderth, J; Schulz, E; Deutsch, A; Mohan, S; Ulz, P; Neumeister, P; Rakheja, D; Gao, X; Hinck, A; Weintraub, ST; DeBerardinis, RJ; Sill, H; Dahia, PL; Aguiar, RC D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2.
Nat Commun. 2015; 6(7):7768-7768 [OPEN ACCESS]
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Mayr, C; Neureiter, D; Pichler, M; Berr, F; Wagner, A; Kiesslich, T; Namberger, K Cytotoxic effects of chemokine receptor 4 inhibition by AMD3100 in biliary tract cancer cells: Potential drug synergism with gemcitabine.
Mol Med Rep. 2015; 12(2):2247-2252 [OPEN ACCESS]
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Milewska, M; Romano, D; Herrero, A; Guerriero, ML; Birtwistle, M; Quehenberger, F; Hatzl, S; Kholodenko, BN; Segatto, O; Kolch, W; Zebisch, A Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation.
PLoS One. 2015; 10(6):e0129859-e0129859 [OPEN ACCESS]
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