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Publikationen

Suchbegriffe: GENE EXPRESSION REGULATION - DRUG EFFECTS , . Treffer: 81

2021

Baković, P; Kesić, M; Perić, M; Bečeheli, I; Horvatiček, M; George, M; Čičin-Šain, L; Desoye, G; Wadsack, C; Panzenboeck, U; Štefulj, J Differential Serotonin Uptake Mechanisms at the Human Maternal-Fetal Interface.
INT J MOL SCI. 2021; 22(15): Doi: 10.3390/ijms22157807 [OPEN ACCESS]
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2020

Gerndt, S; Chen, CC; Chao, YK; Yuan, Y; Burgstaller, S; Scotto, Rosato, A; Krogsaeter, E; Urban, N; Jacob, K; Nguyen, ONP; Miller, MT; Keller, M; Vollmar, AM; Gudermann, T; Zierler, S; Schredelseker, J; Schaefer, M; Biel, M; Malli, R; Wahl-Schott, C; Bracher, F; Patel, S; Grimm, C Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
Elife. 2020; 9: Doi: 10.7554/eLife.54712 [OPEN ACCESS]
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Olivieri, O; Speziali, G; Castagna, A; Pattini, P; Udali, S; Pizzolo, F; Liesinger, L; Gindlhuber, J; Tomin, T; Schittmayer, M; Birner-Gruenberger, R; Cecconi, D; Girelli, D; Friso, S; Martinelli, N The Positive Association between Plasma Myristic Acid and ApoCIII Concentrations in Cardiovascular Disease Patients Is Supported by the Effects of Myristic Acid in HepG2 Cells.
J Nutr. 2020; 150(10):2707-2715 Doi: 10.1093/jn/nxaa202
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2019

Carmona-Gutierrez, D; Zimmermann, A; Kainz, K; Pietrocola, F; Chen, G; Maglioni, S; Schiavi, A; Nah, J; Mertel, S; Beuschel, CB; Castoldi, F; Sica, V; Trausinger, G; Raml, R; Sommer, C; Schroeder, S; Hofer, SJ; Bauer, MA; Pendl, T; Tadic, J; Dammbrueck, C; Hu, Z; Ruckenstuhl, C; Eisenberg, T; Durand, S; Bossut, N; Aprahamian, F; Abdellatif, M; Sedej, S; Enot, DP; Wolinski, H; Dengjel, J; Kepp, O; Magnes, C; Sinner, F; Pieber, TR; Sadoshima, J; Ventura, N; Sigrist, SJ; Kroemer, G; Madeo, F The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.
Nat Commun. 2019; 10(1):651-651 Doi: 10.1038/s41467-019-08555-w [OPEN ACCESS]
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Paraíso, AF; Sousa, JN; Andrade, JMO; Mangabeira, ES; Lelis, DF; de Paula, AMB; Martins, AMEB; Lima, WJN; Guimarães, ALS; Melo, GA; Schwarz, M; Santos, SHS Oral gallic acid improves metabolic profile by modulating SIRT1 expression in obese mice brown adipose tissue: A molecular and bioinformatic approach.
Life Sci. 2019; 237(1):116914-116914 Doi: 10.1016/j.lfs.2019.116914
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Theiler, A; Bärnthaler, T; Platzer, W; Richtig, G; Peinhaupt, M; Rittchen, S; Kargl, J; Ulven, T; Marsh, LM; Marsche, G; Schuligoi, R; Sturm, EM; Heinemann, A Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival.
J Allergy Clin Immunol. 2019; 144(3):764-776 Doi: 10.1016/j.jaci.2019.05.002 [OPEN ACCESS]
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2018

Kretschmer, N; Deutsch, A; Durchschein, C; Rinner, B; Stallinger, A; Higareda-Almaraz, JC; Scheideler, M; Lohberger, B; Bauer, R Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction.
Molecules. 2018; 23(11): Doi: 10.3390/molecules23112823 [OPEN ACCESS]
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Mkrtchyan, GV; Üçal, M; Müllebner, A; Dumitrescu, S; Kames, M; Moldzio, R; Molcanyi, M; Schaefer, S; Weidinger, A; Schaefer, U; Hescheler, J; Duvigneau, JC; Redl, H; Bunik, VI; Kozlov, AV Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex.
BBA - Bioenergetics. 2018; 1859(9): 925-931. Doi: 10.1016/j.bbabio.2018.05.005 [OPEN ACCESS]
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Xia, W; Pessentheiner, AR; Hofer, DC; Amor, M; Schreiber, R; Schoiswohl, G; Eichmann, TO; Walenta, E; Itariu, B; Prager, G; Hackl, H; Stulnig, T; Kratky, D; Rülicke, T; Bogner-Strauss, JG Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance.
Cell Rep. 2018; 23(7):1948-1961 Doi: 10.1016/j.celrep.2018.04.055 [OPEN ACCESS]
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2017

Diomede, F; Thangavelu, SR; Merciaro, I; D'Orazio, M; Bramanti, P; Mazzon, E; Trubiani, O Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation.
Eur J Histochem. 2017; 61(3):2826-2826 Doi: 10.4081/ejh.2017.2826 [OPEN ACCESS]
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Schwetz, V; Trummer, C; Pandis, M; Grübler, MR; Verheyen, N; Gaksch, M; Zittermann, A; März, W; Aberer, F; Lang, A; Treiber, G; Friedl, C; Obermayer-Pietsch, B; Pieber, TR; Tomaschitz, A; Pilz, S Effects of Vitamin D Supplementation on Bone Turnover Markers: A Randomized Controlled Trial.
Nutrients. 2017; 9(5): Doi: 10.3390/nu9050432 [OPEN ACCESS]
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Trummer, C; Schwetz, V; Pandis, M; Grübler, MR; Verheyen, N; Gaksch, M; Zittermann, A; März, W; Aberer, F; Lang, A; Friedl, C; Tomaschitz, A; Obermayer-Pietsch, B; Pieber, TR; Pilz, S; Treiber, G Effects of Vitamin D Supplementation on IGF-1 and Calcitriol: A Randomized-Controlled Trial.
Nutrients. 2017; 9(6): Doi: 10.3390/nu9060623 [OPEN ACCESS]
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2016

Alesutan, I; Feger, M; Tuffaha, R; Castor, T; Musculus, K; Buehling, SS; Heine, CL; Kuro-O, M; Pieske, B; Schmidt, K; Tomaschitz, A; Maerz, W; Pilz, S; Meinitzer, A; Voelkl, J; Lang, F Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine.
Cardiovasc Res. 2016; 110(3):408-418 Doi: 10.1093/cvr/cvw062 [OPEN ACCESS]
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Singh, TP; Zhang, HH; Borek, I; Wolf, P; Hedrick, MN; Singh, SP; Kelsall, BL; Clausen, BE; Farber, JM Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation.
Nat Commun. 2016; 7(12):13581-13581 Doi: 10.1038/ncomms13581 [OPEN ACCESS]
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2015

Adage, T; Konya, V; Weber, C; Strutzmann, E; Fuchs, T; Zankl, C; Gerlza, T; Jeremic, D; Heinemann, A; Kungl, AJ Targeting glycosaminoglycans in the lung by an engineered CXCL8 as a novel therapeutic approach to lung inflammation.
Eur J Pharmacol. 2015; 748(10):83-92 Doi: 10.1016/j.ejphar.2014.12.019
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Haider, T; Höftberger, R; Rüger, B; Mildner, M; Blumer, R; Mitterbauer, A; Buchacher, T; Sherif, C; Altmann, P; Redl, H; Gabriel, C; Gyöngyösi, M; Fischer, MB; Lubec, G; Ankersmit, HJ The secretome of apoptotic human peripheral blood mononuclear cells attenuates secondary damage following spinal cord injury in rats.
Exp Neurol. 2015; 267(3):230-242 Doi: 10.1016/j.expneurol.2015.03.013 [OPEN ACCESS]
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Leitner, L; Jürets, A; Itariu, BK; Keck, M; Prager, G; Langer, F; Grablowitz, V; Zeyda, M; Stulnig, TM Osteopontin promotes aromatase expression and estradiol production in human adipocytes.
Breast Cancer Res Treat. 2015; 154(1):63-69 Doi: 10.1007/s10549-015-3603-0
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Sahu-Osen, A; Montero-Moran, G; Schittmayer, M; Fritz, K; Dinh, A; Chang, YF; McMahon, D; Boeszoermenyi, A; Cornaciu, I; Russell, D; Oberer, M; Carman, GM; Birner-Gruenberger, R; Brasaemle, DL CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization.
J Lipid Res. 2015; 56(1):109-121 Doi: 10.1194/jlr.M055004 [OPEN ACCESS]
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Zakharova, IO; Sokolova, TV; Akhmetshina, AO; Avrova, NF Role of Protein Kinase Akt Activation in Protective Effect of Ganglioside GM1 on PC12 Cells Exposed to H2O2.
Bull Exp Biol Med. 2015; 159(5): 610-613. Doi: 10.1007/s10517-015-3026-2
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2014

Alkhani, H; Ase, AR; Grant, R; O'Donnell, D; Groschner, K; Séguéla, P Contribution of TRPC3 to store-operated calcium entry and inflammatory transductions in primary nociceptors.
Mol Pain. 2014; 10(6):43-43 Doi: 10.1186/1744-8069-10-43 [OPEN ACCESS]
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Chuang, CY; Degendorfer, G; Hammer, A; Whitelock, JM; Malle, E; Davies, MJ Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells.
Biochem J. 2014; 459(2):313-322 Doi: 10.1042/BJ20131471 [OPEN ACCESS]
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Folci, A; Mapelli, L; Sassone, J; Prestori, F; D'Angelo, E; Bassani, S; Passafaro, M Loss of hnRNP K impairs synaptic plasticity in hippocampal neurons.
J Neurosci. 2014; 34(27): 9088-9095. Doi: 10.1523/JNEUROSCI.0303-14.2014 [OPEN ACCESS]
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Fröhlich, E; Meindl, C; Wagner, K; Leitinger, G; Roblegg, E Use of whole genome expression analysis in the toxicity screening of nanoparticles.
Toxicol Appl Pharmacol. 2014; 280(2):272-284 Doi: 10.1016/j.taap.2014.07.017 [OPEN ACCESS]
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Hilz, FM; Ahrens, P; Grad, S; Stoddart, MJ; Dahmani, C; Wilken, FL; Sauerschnig, M; Niemeyer, P; Zwingmann, J; Burgkart, R; von Eisenhart-Rothe, R; Südkamp, NP; Weyh, T; Imhoff, AB; Alini, M; Salzmann, GM Influence of extremely low frequency, low energy electromagnetic fields and combined mechanical stimulation on chondrocytes in 3-D constructs for cartilage tissue engineering.
Bioelectromagnetics. 2014; 35(2): 116-128. Doi: 10.1002/bem.21822
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Kleine, M; Worbs, T; Schrem, H; Vondran, FW; Kaltenborn, A; Klempnauer, J; Förster, R; Josenhans, C; Suerbaum, S; Bektas, H Helicobacter hepaticus induces an inflammatory response in primary human hepatocytes.
PLoS One. 2014; 9(6): e99713-e99713. Doi: 10.1371/journal.pone.0099713 [OPEN ACCESS]
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Step, SE; Lim, HW; Marinis, JM; Prokesch, A; Steger, DJ; You, SH; Won, KJ; Lazar, MA Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers.
Genes Dev. 2014; 28(9): 1018-1028. Doi: 10.1101/gad.237628.114 [OPEN ACCESS]
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2013

Doedens, AL; Phan, AT; Stradner, MH; Fujimoto, JK; Nguyen, JV; Yang, E; Johnson, RS; Goldrath, AW Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen.
Nat Immunol. 2013; 14(11):1173-1182 Doi: 10.1038/ni.2714 [OPEN ACCESS]
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Hofrichter, J; Krohn, M; Schumacher, T; Lange, C; Feistel, B; Walbroel, B; Heinze, HJ; Crockett, S; Sharbel, TF; Pahnke, J Reduced Alzheimer's disease pathology by St. John's Wort treatment is independent of hyperforin and facilitated by ABCC1 and microglia activation in mice.
Curr Alzheimer Res. 2013; 10(10):1057-1069 Doi: 10.2174/15672050113106660171 [OPEN ACCESS]
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Kosaraju, J; Gali, CC; Khatwal, RB; Dubala, A; Chinni, S; Holsinger, RM; Madhunapantula, VS; Muthureddy Nataraj, SK; Basavan, D Saxagliptin: a dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease.
Neuropharmacology. 2013; 72(3):291-300 Doi: 10.1016/j.neuropharm.2013.04.008
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Schwarz, H; Posselt, G; Wurm, P; Ulbing, M; Duschl, A; Horejs-Hoeck, J TLR8 and NOD signaling synergistically induce the production of IL-1β and IL-23 in monocyte-derived DCs and enhance the expression of the feedback inhibitor SOCS2.
Immunobiology. 2013; 218(4):533-542 Doi: 10.1016/j.imbio.2012.06.007
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Yu, A; Zheng, Y; Zhang, R; Huang, J; Zhu, Z; Zhou, R; Jin, D; Yang, Z Resistin impairs SIRT1 function and induces senescence-associated phenotype in hepatocytes.
Mol Cell Endocrinol. 2013; 377(1-2):23-32 Doi: 10.1016/j.mce.2013.06.028
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2012

Kirsch, AH; Riegelbauer, V; Tagwerker, A; Rudnicki, M; Rosenkranz, AR; Eller, K The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response.
Am J Physiol Renal Physiol. 2012; 303(4):F569-F575 Doi: 10.1152/ajprenal.00180.2012 [OPEN ACCESS]
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Kwapiszewska, G; Chwalek, K; Marsh, LM; Wygrecka, M; Wilhelm, J; Best, J; Egemnazarov, B; Weisel, FC; Osswald, SL; Schermuly, RT; Olschewski, A; Seeger, W; Weissmann, N; Eickelberg, O; Fink, L BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension.
Am J Pathol. 2012; 181(6):2018-2029 Doi: 10.1016/j.ajpath.2012.08.028 [OPEN ACCESS]
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Oberbach, A; Schlichting, N; Heinrich, M; Till, H; Stolzenburg, JU; Neuhaus, J Free fatty acid palmitate impairs the vitality and function of cultured human bladder smooth muscle cells.
PLoS One. 2012; 7(7):e41026-e41026 Doi: 10.1371/journal.pone.0041026 [OPEN ACCESS]
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Philipose, S; Konya, V; Lazarevic, M; Pasterk, LM; Marsche, G; Frank, S; Peskar, BA; Heinemann, A; Schuligoi, R Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation.
PLoS One. 2012; 7(8):e40222-e40222 Doi: 10.1371/journal.pone.0040222 [OPEN ACCESS]
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2011

Chen, F; Zhu, Y; Tang, X; Sun, Y; Jia, W; Sun, Y; Han, X Dynamic regulation of PDX-1 and FoxO1 expression by FoxA2 in dexamethasone-induced pancreatic β-cells dysfunction.
Endocrinology. 2011; 152(5): 1779-1788. Doi: 10.1210/en.2010-1048 [OPEN ACCESS]
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Dichlberger, A; Schlager, S; Lappalainen, J; Käkelä, R; Hattula, K; Butcher, SJ; Schneider, WJ; Kovanen, PT Lipid body formation during maturation of human mast cells.
J Lipid Res. 2011; 52(12):2198-2208 Doi: 10.1194/jlr.M019737 [OPEN ACCESS]
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Erttmann, SF; Bast, A; Seidel, J; Breitbach, K; Walther, R; Steinmetz, I PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2.
Free Radic Biol Med. 2011; 51(3):626-640 Doi: 10.1016/j.freeradbiomed.2011.05.022
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Grunert, T; Leitner, NR; Marchetti-Deschmann, M; Miller, I; Wallner, B; Radwan, M; Vogl, C; Kolbe, T; Kratky, D; Gemeiner, M; Allmaier, G; Müller, M; Strobl, B A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C).
J Proteomics. 2011; 74(12): 2866-2880. Doi: 10.1016/j.jprot.2011.07.006 [OPEN ACCESS]
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2010

Lindenmair, A; Wolbank, S; Stadler, G; Meinl, A; Peterbauer-Scherb, A; Eibl, J; Polin, H; Gabriel, C; van Griensven, M; Redl, H Osteogenic differentiation of intact human amniotic membrane.
Biomaterials. 2010; 31(33): 8659-8665. Doi: 10.1016/j.biomaterials.2010.07.090
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Mitrovic, M; Shahbazian, A; Bock, E; Pabst, MA; Holzer, P Chemo-nociceptive signalling from the colon is enhanced by mild colitis and blocked by inhibition of transient receptor potential ankyrin 1 channels.
BRIT J PHARMACOL. 2010; 160(6): 1430-1442. Doi: 10.1111/j.1476-5381.2010.00794.x [OPEN ACCESS]
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Oberbach, A; Schlichting, N; Bluher, M; Kovacs, P; Till, H; Stolzenburg, JU; Neuhaus, J; Palmitate Induced IL-6 and MCP-1 Expression in Human Bladder Smooth Muscle Cells Provides a Link between Diabetes and Urinary Tract Infections.
PLoS One. 2010; 5(5):e10882-e10882 Doi: 10.1371/journal.pone.0010882 [OPEN ACCESS]
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Radovic, B; Hussong, R; Gerhäuser, C; Meinl, W; Frank, N; Becker, H; Köhrle, J Xanthohumol, a prenylated chalcone from hops, modulates hepatic expression of genes involved in thyroid hormone distribution and metabolism.
Mol Nutr Food Res. 2010; 54 Suppl 2(8): S225-S235. Doi: 10.1002/mnfr.200900489
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Villar, V; Kocic, J; Bugarski, D; Jovcic, G; Santibanez, JF SKIP is required for TGF-β1-induced epithelial mesenchymal transition and migration in transformed keratinocytes.
FEBS Lett. 2010; 584(22):4586-4592 Doi: 10.1016/j.febslet.2010.10.020 [OPEN ACCESS]
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2009

Foster, CA; Mechtcheriakova, D; Storch, MK; Balatoni, B; Howard, LM; Bornancin, F; Wlachos, A; Sobanov, J; Kinnunen, A; Baumruker, T FTY720 rescue therapy in the dark agouti rat model of experimental autoimmune encephalomyelitis: expression of central nervous system genes and reversal of blood-brain-barrier damage.
Brain Pathol. 2009; 19(2):254-266 Doi: 10.1111/j.1750-3639.2008.00182.x
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Zirlik, A; Ernst, S; Leugers, A; Willecke, F; Sobel, BE; Bode, C; Nordt, TK Inhibition by fibrates of plasminogen activator inhibitor type-1 expression in human adipocytes and preadipocytes.
THROMB HAEMOSTASIS. 2009; 101(6): 1060-1069. Doi: 10.1160/TH08-03-0164
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2008

Calayir, E; Becker, TM; Kratzer, A; Ebner, B; Panzenböck, U; Stefujl, J; Kostner, GM LXR-agonists regulate ApoM expression differentially in liver and intestine.
Curr Pharm Biotechnol. 2008; 9(6): 516-521. Doi: 10.2174/138920108786786376
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Heazell, AE; Lacey, HA; Jones, CJ; Huppertz, B; Baker, PN; Crocker, IP Effects of oxygen on cell turnover and expression of regulators of apoptosis in human placental trophoblast.
Placenta. 2008; 29(2):175-186 Doi: 10.1016/j.placenta.2007.11.002
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Osto, E; Kouroedov, A; Mocharla, P; Akhmedov, A; Besler, C; Rohrer, L; von, Eckardstein, A; Iliceto, S; Volpe, M; Lüscher, TF; Cosentino, F Inhibition of protein kinase Cbeta prevents foam cell formation by reducing scavenger receptor A expression in human macrophages.
Circulation. 2008; 118(21):2174-82 Doi: 10.1161/CIRCULATIONAHA.108.789537
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Sarkozi, R; Perco, P; Hochegger, K; Enrich, J; Wiesinger, M; Pirklbauer, M; Eder, S; Rudnicki, M; Rosenkranz, AR; Mayer, B; Mayer, G; Schramek, H Bortezomib-induced survival signals and genes in human proximal tubular cells.
J Pharmacol Exp Ther. 2008; 327(3):645-656 Doi: 10.1124/jpet.108.142604 [OPEN ACCESS]
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