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Tomin, T; Schittmayer, M; Sedej, S; Bugger, H; Gollmer, J; Honeder, S; Darnhofer, B; Liesinger, L; Zuckermann, A; Rainer, PP; Birner-Gruenberger, R
Mass Spectrometry-Based Redox and Protein Profiling of Failing Human Hearts.
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Kargl, J; Zhu, X; Zhang, H; Yang, GHY; Friesen, TJ; Shipley, M; Maeda, DY; Zebala, JA; McKay-Fleisch, J; Meredith, G; Mashadi-Hossein, A; Baik, C; Pierce, RH; Redman, MW; Thompson, JC; Albelda, SM; Bolouri, H; Houghton, AM
Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC.
JCI Insight. 2019; 4(24):
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Nonn, O; Güttler, J; Forstner, D; Maninger, S; Zadora, J; Balogh, A; Frolova, A; Glasner, A; Herse, F; Gauster, M
Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction.
Int J Mol Sci. 2019; 20(3):
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Schwarz, S; Gögele, C; Ondruschka, B; Hammer, N; Kohl, B; Schulze-Tanzil, G
Migrating Myofibroblastic Iliotibial Band-Derived Fibroblasts Represent a Promising Cell Source for Ligament Reconstruction.
Int J Mol Sci. 2019; 20(8):
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Strell, C; Paulsson, J; Jin, SB; Tobin, NP; Mezheyeuski, A; Roswall, P; Mutgan, C; Mitsios, N; Johansson, H; Wickberg, SM; Svedlund, J; Nilsson, M; Hall, P; Mulder, J; Radisky, DC; Pietras, K; Bergh, J; Lendahl, U; Wärnberg, F; Östman, A
Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ.
J Natl Cancer Inst. 2019; 111(9):983-995
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Hiden, U; Eyth, CP; Majali-Martinez, A; Desoye, G; Tam-Amersdorfer, C; Huppertz, B; Ghaffari Tabrizi-Wizsy, N
Expression of matrix metalloproteinase 12 is highly specific for non-proliferating invasive trophoblasts in the first trimester and temporally regulated by oxygen-dependent mechanisms including HIF-1A.
Histochem Cell Biol. 2018; 149(1):31-42
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Strutz, J; Cvitic, S; Hackl, H; Kashofer, K; Appel, HM; Thüringer, A; Desoye, G; Koolwijk, P; Hiden, U
Gestational diabetes alters microRNA signatures in human feto-placental endothelial cells depending on fetal sex.
Clin Sci (Lond). 2018; 132(22):2437-2449
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Tsibulak, I; Wieser, V; Degasper, C; Shivalingaiah, G; Wenzel, S; Sprung, S; Lax, SF; Marth, C; Fiegl, H; Zeimet, AG
BRCA1 and BRCA2 mRNA-expression prove to be of clinical impact in ovarian cancer.
Br J Cancer. 2018; 119(6):683-692
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Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.
Nat Genet. 2017; 49(7):993-1004
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Chao, MP; Gentles, AJ; Chatterjee, S; Lan, F; Reinisch, A; Corces, MR; Xavy, S; Shen, J; Haag, D; Chanda, S; Sinha, R; Morganti, RM; Nishimura, T; Ameen, M; Wu, H; Wernig, M; Wu, JC; Majeti, R
Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Cell Stem Cell. 2017; 20(3): 329-344.
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Heitzer, E; Sunitsch, S; Gilg, MM; Lohberger, B; Rinner, B; Kashofer, K; Stündl, N; Ulz, P; Szkandera, J; Leithner, A; Liegl-Atzwanger, B
Expanded molecular profiling of myxofibrosarcoma reveals potentially actionable targets.
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Hlavaty, J; Wolfesberger, B; Hauck, M; Obermayer-Pietsch, B; Fuchs-Baumgartinger, A; Miller, I; Walter, I
Ezrin and moesin expression in canine and feline osteosarcoma.
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Jäger, D; Barth, TFE; Brüderlein, S; Scheuerle, A; Rinner, B; von Witzleben, A; Lechel, A; Meyer, P; Mayer-Steinacker, R; Baer, AV; Schultheiss, M; Wirtz, CR; Möller, P; Mellert, K
HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas.
Sci Rep. 2017; 7(1):2032-2032
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Karlsson, J; Kroneis, T; Jonasson, E; Larsson, E; Ståhlberg, A
Transcriptomic Characterization of the Human Cell Cycle in Individual Unsynchronized Cells.
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Schütte, M; Risch, T; Abdavi-Azar, N; Boehnke, K; Schumacher, D; Keil, M; Yildiriman, R; Jandrasits, C; Borodina, T; Amstislavskiy, V; Worth, CL; Schweiger, C; Liebs, S; Lange, M; Warnatz, HJ; Butcher, LM; Barrett, JE; Sultan, M; Wierling, C; Golob-Schwarzl, N; Lax, S; Uranitsch, S; Becker, M; Welte, Y; Regan, JL; Silvestrov, M; Kehler, I; Fusi, A; Kessler, T; Herwig, R; Landegren, U; Wienke, D; Nilsson, M; Velasco, JA; Garin-Chesa, P; Reinhard, C; Beck, S; Schäfer, R; Regenbrecht, CR; Henderson, D; Lange, B; Haybaeck, J; Keilholz, U; Hoffmann, J; Lehrach, H; Yaspo, ML
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Nat Commun. 2017; 8(2):14262-14262
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Nat Genet. 2017; 49(9):1373-1384
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Staiger, AM; Duppel, J; Dengler, MA; van der Kuip, H; Vöhringer, MC; Aulitzky, WE; Rosenwald, A; Ott, G; Horn, H
An analysis of the role of follicular lymphoma-associated fibroblasts to promote tumor cell viability following drug-induced apoptosis.
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von der Heide, EK; Neumann, M; Vosberg, S; James, AR; Schroeder, MP; Ortiz-Tanchez, J; Isaakidis, K; Schlee, C; Luther, M; Jöhrens, K; Anagnostopoulos, I; Mochmann, LH; Nowak, D; Hofmann, WK; Greif, PA; Baldus, CD
Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients.
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Barghash, A; Golob-Schwarzl, N; Helms, V; Haybaeck, J; Kessler, SM
Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma.
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Björklund, ÅK; Forkel, M; Picelli, S; Konya, V; Theorell, J; Friberg, D; Sandberg, R; Mjösberg, J
The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing.
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Harada, Y; Izumi, H; Noguchi, H; Kuma, A; Kawatsu, Y; Kimura, T; Kitada, S; Uramoto, H; Wang, KY; Sasaguri, Y; Hijioka, H; Miyawaki, A; Oya, R; Nakayama, T; Kohno, K; Yamada, S
Strong expression of polypeptide N-acetylgalactosaminyltransferase 3 independently predicts shortened disease-free survival in patients with early stage oral squamous cell carcinoma.
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ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
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He, JC; Yao, W; Wang, JM; Schemmer, P; Yang, Y; Liu, Y; Qian, YW; Qi, WP; Zhang, J; Shen, Q; Yang, T
TACC3 overexpression in cholangiocarcinoma correlates with poor prognosis and is a potential anti-cancer molecular drug target for HDAC inhibitors.
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Kienesberger, S; Cox, LM; Livanos, A; Zhang, XS; Chung, J; Perez-Perez, GI; Gorkiewicz, G; Zechner, EL; Blaser, MJ
Gastric Helicobacter pylori Infection Affects Local and Distant Microbial Populations and Host Responses.
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Klanert, G; Jadhav, V; Shanmukam, V; Diendorfer, A; Karbiener, M; Scheideler, M; Bort, JH; Grillari, J; Hackl, M; Borth, N
A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines.
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Ohtsuka, M; Ling, H; Ivan, C; Pichler, M; Matsushita, D; Goblirsch, M; Stiegelbauer, V; Shigeyasu, K; Zhang, X; Chen, M; Vidhu, F; Bartholomeusz, GA; Toiyama, Y; Kusunoki, M; Doki, Y; Mori, M; Song, S; Gunther, JR; Krishnan, S; Slaby, O; Goel, A; Ajani, JA; Radovich, M; Calin, GA
H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.
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Spinner, S; Crispatzu, G; Yi, JH; Munkhbaatar, E; Mayer, P; Höckendorf, U; Müller, N; Li, Z; Schader, T; Bendz, H; Hartmann, S; Yabal, M; Pechloff, K; Heikenwalder, M; Kelly, GL; Strasser, A; Peschel, C; Hansmann, ML; Ruland, J; Keller, U; Newrzela, S; Herling, M; Jost, PJ
Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance.
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Epidermal elafin expression is an indicator of poor prognosis in cutaneous graft-versus-host disease.
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Dorn, I; Klich, K; Arauzo-Bravo, MJ; Radstaak, M; Santourlidis, S; Ghanjati, F; Radke, TF; Psathaki, OE; Hargus, G; Kramer, J; Einhaus, M; Kim, JB; Kögler, G; Wernet, P; Schöler, HR; Schlenke, P; Zaehres, H
Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin.
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Hackl, H; Steinleitner, K; Lind, K; Hofer, S; Tosic, N; Pavlovic, S; Suvajdzic, N; Sill, H; Wieser, R
A gene expression profile associated with relapse of cytogenetically normal acute myeloid leukemia is enriched for leukemia stem cell genes.
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Microarray profiling of preselected CHO host cell subclones identifies gene expression patterns associated with increased production capacity.
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Doi: 10.1002/biot.201400857
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Schwarzenbacher, D; Stiegelbauer, V; Deutsch, A; Ress, AL; Aigelsreiter, A; Schauer, S; Wagner, K; Langsenlehner, T; Resel, M; Gerger, A; Ling, H; Ivan, C; Calin, GA; Hoefler, G; Rinner, B; Pichler, M
Low spinophilin expression enhances aggressive biological behavior of breast cancer.
Oncotarget. 2015; 6(13):11191-11202
Doi: 10.18632/oncotarget.3586
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Siwetz, M; Dieber-Rotheneder, M; Cervar-Zivkovic, M; Kummer, D; Kremshofer, J; Weiss, G; Herse, F; Huppertz, B; Gauster, M
Placental fractalkine is up-regulated in severe early-onset preeclampsia.
Am J Pathol. 2015; 185(5):1334-1343
Doi: 10.1016/j.ajpath.2015.01.019
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Wende, AR; O'Neill, BT; Bugger, H; Riehle, C; Tuinei, J; Buchanan, J; Tsushima, K; Wang, L; Caro, P; Guo, A; Sloan, C; Kim, BJ; Wang, X; Pereira, RO; McCrory, MA; Nye, BG; Benavides, GA; Darley-Usmar, VM; Shioi, T; Weimer, BC; Abel, ED
Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.
Mol Cell Biol. 2015; 35(5): 831-846.
Doi: 10.1128/MCB.01109-14
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Zuckermann, M; Hovestadt, V; Knobbe-Thomsen, CB; Zapatka, M; Northcott, PA; Schramm, K; Belic, J; Jones, DT; Tschida, B; Moriarity, B; Largaespada, D; Roussel, MF; Korshunov, A; Reifenberger, G; Pfister, SM; Lichter, P; Kawauchi, D; Gronych, J
Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling.
Nat Commun. 2015; 6(3):7391-7391
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Beer, L; Seemann, R; Ristl, R; Ellinger, A; Kasiri, MM; Mitterbauer, A; Zimmermann, M; Gabriel, C; Gyöngyösi, M; Klepetko, W; Mildner, M; Ankersmit, HJ
High dose ionizing radiation regulates micro RNA and gene expression changes in human peripheral blood mononuclear cells.
BMC Genomics. 2014; 15(10):814-814
Doi: 10.1186/1471-2164-15-814
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Biasin, V; Chwalek, K; Wilhelm, J; Best, J; Marsh, LM; Ghanim, B; Klepetko, W; Fink, L; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G
Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.
Int J Biochem Cell Biol. 2014; 54(3):137-148
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El-Heliebi, A; Kroneis, T; Wagner, K; Meditz, K; Kolb, D; Feichtinger, J; Thallinger, GG; Quehenberger, F; Liegl-Atzwanger, B; Rinner, B
Resolving tumor heterogeneity: genes involved in chordoma cell development identified by low-template analysis of morphologically distinct cells.
PLoS One. 2014; 9(2):e87663-e87663
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Emmert-Streib, F; de Matos Simoes, R; Glazko, G; McDade, S; Haibe-Kains, B; Holzinger, A; Dehmer, M; Campbell, F
Functional and genetic analysis of the colon cancer network.
BMC Bioinformatics. 2014; 15 Suppl 6(16):S6-S6
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Filipits, M; Nielsen, TO; Rudas, M; Greil, R; Stöger, H; Jakesz, R; Bago-Horvath, Z; Dietze, O; Regitnig, P; Gruber-Rossipal, C; Müller-Holzner, E; Singer, CF; Mlineritsch, B; Dubsky, P; Bauernhofer, T; Hubalek, M; Knauer, M; Trapl, H; Fesl, C; Schaper, C; Ferree, S; Liu, S; Cowens, JW; Gnant, M; Austrian Breast and Colorectal Cancer Study Group
The PAM50 risk-of-recurrence score predicts risk for late distant recurrence after endocrine therapy in postmenopausal women with endocrine-responsive early breast cancer.
Clin Cancer Res. 2014; 20(5):1298-1305
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Fink, SE; Gandhi, MK; Nourse, JP; Keane, C; Jones, K; Crooks, P; Jöhrens, K; Korfel, A; Schmidt, H; Neumann, S; Tiede, A; Jäger, U; Dührsen, U; Neuhaus, R; Dreyling, M; Borchert, K; Südhoff, T; Riess, H; Anagnostopoulos, I; Trappe, RU
A comprehensive analysis of the cellular and EBV-specific microRNAome in primary CNS PTLD identifies different patterns among EBV-associated tumors.
Am J Transplant. 2014; 14(11):2577-2587
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Ghaffari-Tabrizi-Wizsy, N; Cvitic, S; Tam-Amersdorfer, C; Bilban, M; Majali-Martinez, A; Schramke, K; Desoye, G; Hiden, U
Different Preference of Degradome in Invasion versus Angiogenesis.
Cells Tissues Organs. 2014; 200(3-4):181-194
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Lee, W; Teckie, S; Wiesner, T; Ran, L; Prieto Granada, CN; Lin, M; Zhu, S; Cao, Z; Liang, Y; Sboner, A; Tap, WD; Fletcher, JA; Huberman, KH; Qin, LX; Viale, A; Singer, S; Zheng, D; Berger, MF; Chen, Y; Antonescu, CR; Chi, P
PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.
Nat Genet. 2014; 46(11): 1227-1232.
Doi: 10.1038/ng.3095
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Lichtenegger, S; Bina, I; Roier, S; Bauernfeind, S; Keidel, K; Schild, S; Anthony, M; Reidl, J
Characterization of lactate utilization and its implication on the physiology of Haemophilus influenzae.
Int J Med Microbiol. 2014; 304(3-4): 490-498.
Doi: 10.1016/j.ijmm.2014.02.010
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Maccani, A; Hackl, M; Leitner, C; Steinfellner, W; Graf, AB; Tatto, NE; Karbiener, M; Scheideler, M; Grillari, J; Mattanovich, D; Kunert, R; Borth, N; Grabherr, R; Ernst, W
Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation.
Appl Microbiol Biotechnol. 2014; 98(17):7535-7548
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Pandey, V; Sultan, M; Kashofer, K; Ralser, M; Amstislavskiy, V; Starmann, J; Osprian, I; Grimm, C; Hache, H; Yaspo, ML; Sültmann, H; Trauner, M; Denk, H; Zatloukal, K; Lehrach, H; Wierling, C
Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains.
PLoS One. 2014; 9(10):e111006-e111006
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Peintinger, F
Using molecular profiles to tailor treatment in breast cancer: are they ready for prime time?
Curr Opin Obstet Gynecol. 2014; 26(1):21-26
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Rao, S; Tortola, L; Perlot, T; Wirnsberger, G; Novatchkova, M; Nitsch, R; Sykacek, P; Frank, L; Schramek, D; Komnenovic, V; Sigl, V; Aumayr, K; Schmauss, G; Fellner, N; Handschuh, S; Glösmann, M; Pasierbek, P; Schlederer, M; Resch, GP; Ma, Y; Yang, H; Popper, H; Kenner, L; Kroemer, G; Penninger, JM
A dual role for autophagy in a murine model of lung cancer.
Nat Commun. 2014; 5(5):3056-3056
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Rolny, IS; Minnaard, J; Racedo, SM; Pérez, PF
Murine model of Bacillus cereus gastrointestinal infection.
J Med Microbiol. 2014; 63(Pt 12): 1741-1749.
Doi: 10.1099/jmm.0.079939-0
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Sapienza, MR; Fuligni, F; Agostinelli, C; Tripodo, C; Righi, S; Laginestra, MA; Pileri, A; Mancini, M; Rossi, M; Ricci, F; Gazzola, A; Melle, F; Mannu, C; Ulbar, F; Arpinati, M; Paulli, M; Maeda, T; Gibellini, D; Pagano, L; Pimpinelli, N; Santucci, M; Cerroni, L; Croce, CM; Facchetti, F; Piccaluga, PP; Pileri, SA; AIRC 5xMille consortium ‘Genetics-driven targeted management of lymphoid malignancies and the Italian Registry on Blastic Plasmacytoid Dendritic Cell Neoplasm
Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition.
Leukemia. 2014; 28(8):1606-1616
Doi: 10.1038/leu.2014.64
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