Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Publikationen
Suchbegriffe: GIRK1, . Treffer: 20
2022
Pelzmann, B; Hatab, A; Scheruebel, S; Langthaler, S; Rienmueller, T; Sokolowski, A; Gorischek, A; Platzer, D; Zorn-Pauly, K; Jahn, SW; Bauernhofer, T; Schreibmayer, W
Consequences of somatic mutations of GIRK1 detected in primary malign tumors on expression and function of G-protein activated, inwardly rectifying, K+ channels.
Front Oncol. 2022; 12:998907
Doi: 10.3389/fonc.2022.998907
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2019
Schratter, G; Scheruebel, S; Langthaler, S; Ester, K; Pelzmann, B; Ghaffari-Tabrizi-Wizsy, N; Rezania, S; Gorischek, A; Platzer, D; Zorn-Pauly, K; Ahammer, H; Prokesch, A; Stanzer, S; Devaney, TTJ; Schmidt, K; Jahn, SW; Prassl, R; Bauernhofer, T; Schreibmayer, W;
GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A.
SCI REP. 2019; 9: 19277
Doi: 10.1038/s41598-019-55683-w
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2016
Kammerer, S; Sokolowski, A; Hackl, H; Platzer, D; Jahn, SW; El-Heliebi, A; Schwarzenbacher, D; Stiegelbauer, V; Pichler, M; Rezania, S; Fiegl, H; Peintinger, F; Regitnig, P; Hoefler, G; Schreibmayer, W; Bauernhofer, T
KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients.
Oncotarget. 2016; 7(51):84705-84717
Doi: 10.18632/oncotarget.13224
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Rezania, S; Kammerer, S; Li, C; Steinecker-Frohnwieser, B; Gorischek, A; DeVaney, TT; Verheyen, S; Passegger, CA; Tabrizi-Wizsy, NG; Hackl, H; Platzer, D; Zarnani, AH; Malle, E; Jahn, SW; Bauernhofer, T; Schreibmayer, W
Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.
BMC Cancer. 2016; 16(1):628-628
Doi: 10.1186/s12885-016-2664-8
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2013
Treiber, F; Rosker, C; Keren-Raifman, T; Steinecker, B; Gorischek, A; Dascal, N; Schreibmayer, W
Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase.
Biochim Biophys Acta. 2013; 1828(4):1214-1221
Doi: 10.1016/j.bbamem.2012.12.016
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2010
Wagner, V; Stadelmeyer, E; Riederer, M; Regitnig, P; Gorischek, A; Devaney, T; Schmidt, K; Tritthart, HA; Hirschberg, K; Bauernhofer, T; Schreibmayer, W
Cloning and characterisation of GIRK1 variants resulting from alternative RNA editing of the KCNJ3 gene transcript in a human breast cancer cell line.
J Cell Biochem. 2010; 110(3):598-608
Doi: 10.1002/jcb.22564
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2009
Müllner, C; Steinecker, B; Gorischek, A; Schreibmayer, W
Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase.
FEBS J. 2009; 276(21): 6218-6226.
Doi: 10.1111/j.1742-4658.2009.07325.x
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2008
Grasser, E; Steinecker, B; Ahammer, H; Schreibmayer, W
Subunit stoichiometry of heterologously expressed G-protein activated inwardly rectifying potassium channels analysed by fluorescence intensity ratio measurement.
Pflugers Arch. 2008; 455(6): 1017-1024.
Doi: 10.1007/s00424-007-0358-4
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2007
Steinecker, B; Rosker, C; Schreibmayer, W
The GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels.
J Recept Signal Transduct Res. 2007; 27(5-6): 369-382.
Doi: 10.1080/10799890701713073
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2004
Milovic, S; Steinecker-Frohnwieser, B; Schreibmayer, W; Weigl, LG
The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus.
J BIOL CHEM. 2004; 279(33): 34240-34249.
Doi: 10.1074/jbc.M403448200
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2003
Ivanina, T; Rishal, I; Varon, D; Mullner, C; Frohnwieser-Steinecke, B; Schreibmayer, W; Dessauer, CW; Dascal, N
Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel.
J Biol Chem. 2003; 278(31):29174-29183
Doi: 10.1074/jbc.M304518200
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Müllner, C; Yakubovich, D; Dessauer, CW; Platzer, D; Schreibmayer, W
Single channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation.
Biophys J. 2003; 84(2 Pt 1):1399-1409
Doi: 10.1016/S0006-3495(03)74954-6
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2001
Weigl, LG; Schreibmayer, W
G protein-gated inwardly rectifying potassium channels are targets for volatile anesthetics.
Mol Pharmacol. 2001; 60(2):282-289
Doi: 10.1124/mol.60.2.282
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2000
Lohberger, B; Groschner, K; Tritthart, H; Schreibmayer, W
IK.ACh activation by arachidonic acid occurs via a G-protein-independent pathway mediated by the GIRK1 subunit.
Pflugers Arch. 2000; 441(2-3):251-256
Doi: 10.1007/s004240000405
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Müllner, C; Vorobiov, D; Bera, AK; Uezono, Y; Yakubovich, D; Frohnwieser-Steinecker, B; Dascal, N; Schreibmayer, W
Heterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinase.
J Gen Physiol. 2000; 115(5):547-558
Doi: 10.1085%2Fjgp.115.5.547
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1999
Jeglitsch, G; Ramos, P; Encabo, A; Tritthart, HA; Esterbauer, H; Groschner, K; Schreibmayer, W
The cardiac acetylcholine-activated, inwardly rectifying K+-channel subunit GIRK1 gives rise to an inward current induced by free oxygen radicals.
Free Radic Biol Med. 1999; 26(3-4):253-259
Doi: 10.1016/S0891-5849(98)00178-6
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1998
Luchian, T; Schreibmayer, W
Ion permeation through a G-protein activated (GIRK1/GIRK5) inwardly rectifying potassium channel.
BBA, BIOMEMBRANES. 1998; 1368(2): 167-170.
Doi: 10.1016/S0005-2736(97)00248-4
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1997
Luchian, T; Dascal, N; Dessauer, C; Platzer, D; Davidson, N; Lester, HA; Schreibmayer, W
A C-terminal peptide of the GIRK1 subunit directly blocks the G protein-activated K+ channel (GIRK) expressed in Xenopus oocytes.
J Physiol. 1997; 505 ( Pt 1)(3):13-22
Doi: 10.1111%2Fj.1469-7793.1997.013bc.x
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1996
Schreibmayer, W; Dessauer, CW; Vorobiov, D; Gilman, AG; Lester, HA; Davidson, N; Dascal, N
Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits.
NATURE. 1996; 380(6575): 624-627.
Doi: 10.1038/380624a0
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1994
Karschin, C; Schreibmayer, W; Dascal, N; Lester, H; Davidson, N; Karschin, A
Distribution and localization of a G protein-coupled inwardly rectifying K+ channel in the rat.
FEBS Lett. 1994; 348(2):139-144
Doi: 10.1016%2F0014-5793%2894%2900590-7
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