Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: EOSINOPHILS, . Treffer: 80

2020

Kienzl, M; Hasenoehrl, C; Valadez-Cosmes, P; Maitz, K; Sarsembayeva, A; Sturm, E; Heinemann, A; Kargl, J; Schicho, R IL-33 reduces tumor growth in models of colorectal cancer with the help of eosinophils
ONCOIMMUNOLOGY. 2020; 9(1): 1776059
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Kluin-Nelemans, HC; Reiter, A; Illerhaus, A; van Anrooij, B; Hartmann, K; Span, LFR; Gorska, A; Niedoszytko, M; Lange, M; Scaffidi, L; Zanotti, R; Bonadonna, P; Perkins, C; Elena, C; Malcovati, L; Shoumariyeh, K; von Bubnoff, N; Parente, R; Triggiani, M; Schwaab, J; Jawhar, M; Caroppo, F; Fortina, AB; Brockow, K; Zink, A; Fuchs, D; Kilbertus, A; Yavuz, AS; Doubek, M; Mattsson, M; Hagglund, H; Panse, J; Sabato, V; Aberer, E; Niederwieser, D; Breynaert, C; Várkonyi, J; Kennedy, V; Lortholary, O; Jakob, T; Hermine, O; Rossignol, J; Arock, M; Gotlib, J; Valent, P; Sperr, WR Prognostic impact of eosinophils in mastocytosis: analysis of 2350 patients collected in the ECNM Registry.
Leukemia. 2020; 34(4):1090-1101 [OPEN ACCESS]
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Knuplez, E; Curcic, S; Theiler, A; Bärnthaler, T; Trakaki, A; Trieb, M; Holzer, M; Heinemann, A; Zimmermann, R; Sturm, EM; Marsche, G Lysophosphatidylcholines inhibit human eosinophil activation and suppress eosinophil migration in vivo.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 158686-158686. [OPEN ACCESS]
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Knuplez, E; Krier-Burris, R; Cao, Y; Marsche, G; O'Sullivan, J; Bochner, BS Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.
J Leukoc Biol. 2020; 108(1):43-58
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2019

Durchschein, F; Eherer, A; Grill, M; Sturm, EM; Pommer, V; Langner, C; Högenauer, C; Schicho, R Involvement of EP2 and EP4 Receptors in Eosinophilic Esophagitis: A Pilot Study.
Dig Dis Sci. 2019; 64(10):2806-2814 [OPEN ACCESS]
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Roula, D; Theiler, A; Luschnig, P; Sturm, GJ; Tomazic, PV; Marsche, G; Heinemann, A; Sturm, EM Apolipoprotein A-IV acts as an endogenous anti-inflammatory protein and is reduced in treatment-naïve allergic patients and allergen-challenged mice.
Allergy. 2019; [OPEN ACCESS]
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Theiler, A; Bärnthaler, T; Platzer, W; Richtig, G; Peinhaupt, M; Rittchen, S; Kargl, J; Ulven, T; Marsh, LM; Marsche, G; Schuligoi, R; Sturm, EM; Heinemann, A Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival.
J Allergy Clin Immunol. 2019; 144(3):764-776 [OPEN ACCESS]
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Trakaki, A; Sturm, GJ; Pregartner, G; Scharnagl, H; Eichmann, TO; Trieb, M; Knuplez, E; Holzer, M; Stadler, JT; Heinemann, A; Sturm, EM; Marsche, G Allergic rhinitis is associated with complex alterations in high-density lipoprotein composition and function.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(10):1280-1292 [OPEN ACCESS]
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2018

Gungl, A; Biasin, V; Wilhelm, J; Olschewski, A; Kwapiszewska, G; Marsh, LM Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner.
Front Immunol. 2018; 9(10):2018-2018 [OPEN ACCESS]
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Peinhaupt, M; Roula, D; Theiler, A; Sedej, M; Schicho, R; Marsche, G; Sturm, EM; Sabroe, I; Rothenberg, ME; Heinemann, A DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator.
J Leukoc Biol. 2018; 104(1): 159-171. [OPEN ACCESS]
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2017

Peinhaupt, M; Sturm, EM; Heinemann, A Prostaglandins and Their Receptors in Eosinophil Function and As Therapeutic Targets.
Front Med (Lausanne). 2017; 4(9):104-104 [OPEN ACCESS]
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2016

Frei, RB; Luschnig, P; Parzmair, GP; Peinhaupt, M; Schranz, S; Fauland, A; Wheelock, CE; Heinemann, A; Sturm, EM Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice.
Allergy. 2016; 71(7):944-956 [OPEN ACCESS]
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Radnai, B; Sturm, EM; Stančić, A; Jandl, K; Labocha, S; Ferreirós, N; Grill, M; Hasenoehrl, C; Gorkiewicz, G; Marsche, G; Heinemann, Á; Högenauer, C; Schicho, R Eosinophils Contribute to Intestinal Inflammation via Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CRTH2, in Experimental Crohn's Disease.
J Crohns Colitis. 2016; 10(9):1087-1095 [OPEN ACCESS]
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2015

Fattahi, F; Vonk, JM; Bulkmans, N; Fleischeuer, R; Gouw, A; Grünberg, K; Mauad, T; Popper, H; Felipe-Silva, A; Vrugt, B; Wright, JL; Yang, HM; Kocks, JW; Hylkema, MN; Postma, DS; Timens, W; Ten Hacken, NH Old dilemma: asthma with irreversible airway obstruction or COPD.
Virchows Arch. 2015; 467(5):583-593 [OPEN ACCESS]
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Harbaum, L; Pollheimer, MJ; Kornprat, P; Lindtner, RA; Bokemeyer, C; Langner, C Peritumoral eosinophils predict recurrence in colorectal cancer.
Mod Pathol. 2015; 28(3):403-413 [OPEN ACCESS]
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Schlager, S; Goeritzer, M; Jandl, K; Frei, R; Vujic, N; Kolb, D; Strohmaier, H; Dorow, J; Eichmann, TO; Rosenberger, A; Wölfler, A; Lass, A; Kershaw, EE; Ceglarek, U; Dichlberger, A; Heinemann, A; Kratky, D Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.
J Leukoc Biol. 2015; 98(5):837-850 [OPEN ACCESS]
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Sturm, EM; Parzmair, GP; Radnai, B; Frei, RB; Sturm, GJ; Hammer, A; Schuligoi, R; Lippe, IT; Heinemann, A Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils.
Eur J Immunol. 2015; 45(5):1548-1559 [OPEN ACCESS]
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2014

Konya, V; Blättermann, S; Jandl, K; Platzer, W; Ottersbach, PA; Marsche, G; Gütschow, M; Kostenis, E; Heinemann, A A biased non-Gαi OXE-R antagonist demonstrates that Gαi protein subunit is not directly involved in neutrophil, eosinophil, and monocyte activation by 5-oxo-ETE.
J Immunol. 2014; 192(10):4774-4782 [OPEN ACCESS]
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Konya, V; Peinhaupt, M; Heinemann, A Adhesion of eosinophils to endothelial cells or substrates under flow conditions.
Methods Mol Biol. 2014; 1178(5):143-156
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Luschnig, P; Frei, R; Lang-Loidolt, D; Rozsasi, A; Tomazic, PV; Lippe, IT; Schuligoi, R; Heinemann, A Altered inhibitory function of the E-type prostanoid receptor 4 in eosinophils and monocytes from aspirin-intolerant patients.
Pharmacology. 2014; 94(5-6):280-286
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Massone, C; Cerroni, L; Heidrun, N; Brunasso, AM; Nunzi, E; Gulia, A; Ambros-Rudolph, CM Histopathological diagnosis of atopic eruption of pregnancy and polymorphic eruption of pregnancy: a study on 41 cases.
Am J Dermatopathol. 2014; 36(10):812-821
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Sturm, EM; Radnai, B; Jandl, K; Stančić, A; Parzmair, GP; Högenauer, C; Kump, P; Wenzl, H; Petritsch, W; Pieber, TR; Schuligoi, R; Marsche, G; Ferreirós, N; Heinemann, A; Schicho, R Opposing roles of prostaglandin D2 receptors in ulcerative colitis.
J Immunol. 2014; 193(2):827-839 [OPEN ACCESS]
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Wutte, N; Palfner, M; Auer, H; Ruckenbauer, G; Valentin, T; Seeber, K; Aberer, W; Krause, R; Hoenigl, M Toxocarosis and putative DRESS syndrome in an oncological patient: a case report.
Wien Klin Wochenschr. 2014; 126 Suppl 1(2):S51-S55 (- Case Report)
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2013

Dyer, KD; Garcia-Crespo, KE; Percopo, CM; Sturm, EM; Rosenberg, HF Protocols for identifying, enumerating, and assessing mouse eosinophils.
Methods Mol Biol. 2013; 1032(12):59-77
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Sturm, EM; Dyer, KD; Percopo, CM; Heinemann, A; Rosenberg, HF Chemotaxis of bone marrow derived eosinophils in vivo: a novel method to explore receptor-dependent trafficking in the mouse.
Eur J Immunol. 2013; 43(8):2217-2228 [OPEN ACCESS]
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Wiednig, M; Beham-Schmid, C; Kranzelbinder, B; Aberer, E Clonal mast cell proliferation in pruriginous skin in hypereosinophilic syndrome.
Dermatology. 2013; 227(1):67-71 (- Case Report) [OPEN ACCESS]
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2012

Fazekas, T; Pruckner, N; Lawitschka, A; Seidel, MG; Eickhoff, P; Pötschger, U; Szpfalusi, Z; Gadner, H; Peters, C Non-atopic IgE and eosinophil cationic protein after allogeneic hematopoietic stem cell transplantation in children.
Ann Hematol. 2012; 91(6):949-956
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Schröder, R; Xue, L; Konya, V; Martini, L; Kampitsch, N; Whistler, JL; Ulven, T; Heinemann, A; Pettipher, R; Kostenis, E PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2.
PLoS One. 2012; 7(3):e33329-e33329 [OPEN ACCESS]
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Sedej, M; Schröder, R; Bell, K; Platzer, W; Vukoja, A; Kostenis, E; Heinemann, A; Waldhoer, M D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells.
J Allergy Clin Immunol. 2012; 129(2): 500.e1- 500.e9
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2011

Konya, V; Philipose, S; Bálint, Z; Olschewski, A; Marsche, G; Sturm, EM; Schicho, R; Peskar, BA; Schuligoi, R; Heinemann, A Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors.
Eur J Immunol. 2011; 41(8):2379-2389 [OPEN ACCESS]
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Luschnig-Schratl, P; Sturm, EM; Konya, V; Philipose, S; Marsche, G; Fröhlich, E; Samberger, C; Lang-Loidolt, D; Gattenlöhner, S; Lippe, IT; Peskar, BA; Schuligoi, R; Heinemann, A EP4 receptor stimulation down-regulates human eosinophil function.
Cell Mol Life Sci. 2011; 68(21): 3573-3587. [OPEN ACCESS]
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Müller, CS; El Shabrawi-Caelen, L "Follicular Swiss cheese" pattern--another histopathologic clue to alopecia areata.
J Cutan Pathol. 2011; 38(2):185-189
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Sturm, EM; Schuligoi, R; Konya, V; Sturm, GJ; Heinemann, A Inhibitory effect of prostaglandin I2 on bone marrow kinetics of eosinophils in the guinea pig.
J Leukoc Biol. 2011; 90(2):285-291 [OPEN ACCESS]
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2010

Kash, N; Ginter-Hanselmayer, G; Cerroni, L Cutaneous mycotic infections with pseudolymphomatous infiltrates.
AMER J DERMATOPATHOL. 2010; 32(5): 514-517.
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Konya, V; Sturm, EM; Schratl, P; Beubler, E; Marsche, G; Schuligoi, R; Lippe, IT; Peskar, BA; Heinemann, A Endothelium-derived prostaglandin I(2) controls the migration of eosinophils.
J Allergy Clin Immunol. 2010; 125(5): 1105-1113.
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Schuligoi, R; Sturm, E; Luschnig, P; Konya, V; Philipose, S; Sedej, M; Waldhoer, M; Peskar, BA; Heinemann, A CRTH2 and D-type prostanoid receptor antagonists as novel therapeutic agents for inflammatory diseases.
Pharmacology. 2010; 85(6): 372-382. [OPEN ACCESS]
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2009

Schratl, P; Heinemann, A Differential involvement of Ca2+ and actin filament in leukocyte shape change.
Pharmacology. 2009; 83(3): 131-140.
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Schuligoi, R; Sedej, M; Waldhoer, M; Vukoja, A; Sturm, EM; Lippe, IT; Peskar, BA; Heinemann, A Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.
J Leukoc Biol. 2009; 85(1): 136-145. [OPEN ACCESS]
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2008

Bush, A; Eber, E The value of FeNO measurement in asthma management: the motion for Yes, it's NO--or, the wrong end of the Stick!
PAEDIATR RESPIR REV. 2008; 9(2): 127-131.
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Royer, JF; Schratl, P; Carrillo, JJ; Jupp, R; Barker, J; Weyman-Jones, C; Beri, R; Sargent, C; Schmidt, JA; Lang-Loidolt, D; Heinemann, A A novel antagonist of prostaglandin D2 blocks the locomotion of eosinophils and basophils.
Eur J Clin Invest. 2008; 38(9):663-671
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Sturm, EM; Schratl, P; Schuligoi, R; Konya, V; Sturm, GJ; Lippe, IT; Peskar, BA; Heinemann, A Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors.
J Immunol. 2008; 181(10): 7273-7283. [OPEN ACCESS]
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2007

Batra, J; Pratap Singh, T; Mabalirajan, U; Sinha, A; Prasad, R; Ghosh, B Association of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels.
Thorax. 2007; 62(1): 16-22. [OPEN ACCESS]
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Cerroni, L; Borroni, RG; Massone, C; Chott, A; Kerl, H Cutaneous B-cell pseudolymphoma at the site of vaccination.
AMER J DERMATOPATHOL. 2007; 29(6): 538-542. (- Case Report)
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Lackner, A; Raggam, RB; Stammberger, H; Beham, A; Braun, H; Kleinhappl, B; Buzina, W; Kittinger, C; Reinisch, S; Berghold, A; Freudenschuss, K; Barth, S; Marth, E The role of interleukin-16 in eosinophilic chronic rhinosinusitis.
Eur Arch Otorhinolaryngol. 2007; 264(8): 887-893.
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Royer, JF; Schratl, P; Lorenz, S; Kostenis, E; Ulven, T; Schuligoi, R; Peskar, BA; Heinemann, A A novel antagonist of CRTH2 blocks eosinophil release from bone marrow, chemotaxis and respiratory burst.
Allergy. 2007; 62(12): 1401-1409. [OPEN ACCESS]
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Schratl, P; Royer, JF; Kostenis, E; Ulven, T; Sturm, EM; Waldhoer, M; Hoefler, G; Schuligoi, R; Lippe, IT; Peskar, BA; Heinemann, A The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking.
J Immunol. 2007; 179(7):4792-4799 [OPEN ACCESS]
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Schuligoi, R; Schmidt, R; Geisslinger, G; Kollroser, M; Peskar, BA; Heinemann, A PGD2 metabolism in plasma: kinetics and relationship with bioactivity on DP1 and CRTH2 receptors.
Biochem Pharmacol. 2007; 74(1): 107-117.
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2006

Hauer, A Cow's milk allergy. Immune mechanisms and clinical manifestations
MONATSSCHR KINDERHEILK 2006 154: 406-+.
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Mathiesen, JM; Christopoulos, A; Ulven, T; Royer, JF; Campillo, M; Heinemann, A; Pardo, L; Kostenis, E On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2.
Mol Pharmacol. 2006; 69(4):1441-1453 [OPEN ACCESS]
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Schratl, P; Sturm, EM; Royer, JF; Sturm, GJ; Lippe, IT; Peskar, BA; Heinemann, A Hierarchy of eosinophil chemoattractants: role of p38 mitogen-activated protein kinase.
EUR J IMMUNOL. 2006; 36(9): 2401-2409. [OPEN ACCESS]
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