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Publikationen

Suchbegriffe: ENZYME ACTIVATION - , . Treffer: 42

2019

Eroglu, E; Saravi, SSS; Sorrentino, A; Steinhorn, B; Michel, T Discordance between eNOS phosphorylation and activation revealed by multispectral imaging and chemogenetic methods.
Proc Natl Acad Sci U S A. 2019; 116(40):20210-20217 Doi: 10.1073/pnas.1910942116 [OPEN ACCESS]
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Gavin, DP; Reen, FJ; Rocha-Martin, J; Abreu-Castilla, I; Woods, DF; Foley, AM; Sánchez-Murcia, PA; Schwarz, M; O'Neill, P; Maguire, AR; O'Gara, F Genome mining and characterisation of a novel transaminase with remote stereoselectivity.
Sci Rep. 2019; 9(1):20285-20285 Doi: 10.1038/s41598-019-56612-7 [OPEN ACCESS]
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Krysko, O; Teufelberger, A; Van Nevel, S; Krysko, DV; Bachert, C Protease/antiprotease network in allergy: The role of Staphylococcus aureus protease-like proteins.
Allergy. 2019; 74(11): 2077-2086. Doi: 10.1111/all.13783
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Zhu, XG; Nicholson Puthenveedu, S; Shen, Y; La, K; Ozlu, C; Wang, T; Klompstra, D; Gultekin, Y; Chi, J; Fidelin, J; Peng, T; Molina, H; Hang, HC; Min, W; Birsoy, K CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4.
MOL CELL. 2019; 74(1): 45-58. Doi: 10.1016/j.molcel.2019.01.037 [OPEN ACCESS]
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2018

Fischer, TH; Eiringhaus, J; Dybkova, N; Saadatmand, A; Pabel, S; Weber, S; Wang, Y; Köhn, M; Tirilomis, T; Ljubojevic, S; Renner, A; Gummert, J; Maier, LS; Hasenfuß, G; El-Armouche, A; Sossalla, S Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca²⁺ leak in human heart failure.
Eur J Heart Fail. 2018; 20(12):1673-1685 Doi: 10.1002/ejhf.1297 [OPEN ACCESS]
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2016

Vogl, F; Humpolickova, J; Amaro, M; Koller, D; Kofeler, H; Zenzmaier, E; Hof, M; Hermetter, A Role of protein kinase C delta in apoptotic signaling of oxidized phospholipids in RAW 264.7 macrophages
BBA-MOL CELL BIOL L. 2016; 1861(4): 320-330. Doi: 10.1016/j.bbalip.2015.12.009
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2015

Boeszoermenyi, A; Nagy, HM; Arthanari, H; Pillip, CJ; Lindermuth, H; Luna, RE; Wagner, G; Zechner, R; Zangger, K; Oberer, M Structure of a CGI-58 motif provides the molecular basis of lipid droplet anchoring.
J Biol Chem. 2015; 290(44):26361-26372 Doi: 10.1074/jbc.M115.682203 [OPEN ACCESS]
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Murali, R; Chandramohan, R; Möller, I; Scholz, SL; Berger, M; Huberman, K; Viale, A; Pirun, M; Socci, ND; Bouvier, N; Bauer, S; Artl, M; Schilling, B; Schimming, T; Sucker, A; Schwindenhammer, B; Grabellus, F; Speicher, MR; Schaller, J; Hillen, U; Schadendorf, D; Mentzel, T; Cheng, DT; Wiesner, T; Griewank, KG Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway.
Oncotarget. 2015; 6(34):36041-36052 Doi: 10.18632/oncotarget.5936 [OPEN ACCESS]
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2013

Huber, MD; Vesely, PW; Datta, K; Gerace, L Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.
J Cell Biol. 2013; 203(3):427-436 Doi: 10.1083/jcb.201305076 [OPEN ACCESS]
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Kocić, J; Santibañez, JF; Krstić, A; Mojsilović, S; Ilić, V; Bugarski, D Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase.
Int J Biochem Cell Biol. 2013; 45(2): 464-475. Doi: 10.1016/j.biocel.2012.11.010
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2012

Veith, C; Marsh, LM; Wygrecka, M; Rutschmann, K; Seeger, W; Weissmann, N; Kwapiszewska, G Paxillin regulates pulmonary arterial smooth muscle cell function in pulmonary hypertension.
Am J Pathol. 2012; 181(5):1621-1633 Doi: 10.1016/j.ajpath.2012.07.026 [OPEN ACCESS]
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2011

Drozdov, I; Svejda, B; Gustafsson, BI; Mane, S; Pfragner, R; Kidd, M; Modlin, IM Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia.
PLoS One. 2011; 6(8):e22457-e22457 Doi: 10.1371/journal.pone.0022457 [OPEN ACCESS]
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2010

Bast, A; Erttmann, SF; Walther, R; Steinmetz, I Influence of iNOS and COX on peroxiredoxin gene expression in primary macrophages.
Free Radic Biol Med. 2010; 49(12):1881-1891 Doi: 10.1016/j.freeradbiomed.2010.09.015
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Gauster, M; Huppertz, B The paradox of caspase 8 in human villous trophoblast fusion.
Placenta. 2010; 31(2): 82-88. Doi: 10.1016/j.placenta.2009.12.007
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Gruber, A; Cornaciu, I; Lass, A; Schweiger, M; Poeschl, M; Eder, C; Kumari, M; Schoiswohl, G; Wolinski, H; Kohlwein, SD; Zechner, R; Zimmermann, R; Oberer, M The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase.
J Biol Chem. 2010; 285(16): 12289-12298. Doi: 10.1074/jbc.M109.064469 [OPEN ACCESS]
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Villar, V; Kocić, J; Santibanez, JF Spred2 inhibits TGF-beta1-induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition.
Int J Cancer. 2010; 127(1): 77-85. Doi: 10.1002/ijc.25045 [OPEN ACCESS]
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2009

Gauster, M; Siwetz, M; Huppertz, B Fusion of villous trophoblast can be visualized by localizing active caspase 8.
Placenta. 2009; 30(6): 547-550. Doi: 10.1016/j.placenta.2009.03.007
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Jost, PJ; Grabow, S; Gray, D; McKenzie, MD; Nachbur, U; Huang, DC; Bouillet, P; Thomas, HE; Borner, C; Silke, J; Strasser, A; Kaufmann, T XIAP discriminates between type I and type II FAS-induced apoptosis.
Nature. 2009; 460(7258):1035-1039 Doi: 10.1038/nature08229 [OPEN ACCESS]
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Krejsgaard, T; Vetter-Kauczok, CS; Woetmann, A; Kneitz, H; Eriksen, KW; Lovato, P; Zhang, Q; Wasik, MA; Geisler, C; Ralfkiaer, E; Becker, JC; Odum, N Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma.
Blood. 2009; 113(23):5896-5904 Doi: 10.1182/blood-2008-09-181024 [OPEN ACCESS]
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2008

Gruber-Olipitz, M; Strobel, T; Chen, WQ; Grotzer, MA; Quehenberger, F; Slavc, I; Lubec, G Synthesis, chaperoning, and metabolism of proteins are regulated by NT-3/TrkC signaling in the medulloblastoma cell line DAOY.
J PROTEOME RES. 2008; 7(5): 1932-1944. Doi: 10.1021/pr700724a
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2007

Houben, R; Ortmann, S; Schrama, D; Herold, MJ; Berberich, I; Reichardt, HM; Becker, JC Activation of the MAP kinase pathway induces apoptosis in the Merkel cell carcinoma cell line UISO.
J Invest Dermatol. 2007; 127(9):2116-2122 Doi: 10.1038/sj.jid.5700857 [OPEN ACCESS]
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Janeway, KA; Liegl, B; Harlow, A; Le, C; Perez-Atayde, A; Kozakewich, H; Corless, CL; Heinrich, NC; Fletcher, JA Pediatric KIT wild-type and platelet-derived growth factor receptor alpha-wild-type gastrointestinal stromal tumors share KIT activation but not mechanisms of genetic progression with adult gastrointestinal stromal tumors.
CANCER RES. 2007; 67(19): 9084-9088. Doi: 10.1158/0008-5472.CAN-07-1938 [OPEN ACCESS]
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Jörgl, A; Platzer, B; Taschner, S; Heinz, LX; Höcher, B; Reisner, PM; Göbel, F; Strobl, H Human Langerhans-cell activation triggered in vitro by conditionally expressed MKK6 is counterregulated by the downstream effector RelB.
Blood. 2007; 109(1):185-193 Doi: 10.1182/blood-2006-05-022954 [OPEN ACCESS]
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2006

Han, Y; Chen, YS; Liu, Z; Bodyak, N; Rigor, D; Bisping, E; Pu, WT; Kang, PM Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition.
Circ Res. 2006; 99(4):415-423 Doi: 10.1161/01.RES.0000237387.05259.a5 [OPEN ACCESS]
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Schmidinger, H; Hermetter, A; Birner-Gruenberger, R Activity-based proteomics: enzymatic activity profiling in complex proteomes.
Amino Acids. 2006; 30(4): 333-350. Doi: 10.1007/s00726-006-0305-2
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Yang, LZ; Kockskämper, J; Heinzel, FR; Hauber, M; Walther, S; Spiess, J; Pieske, B Urocortin II enhances contractility in rabbit ventricular myocytes via CRF(2) receptor-mediated stimulation of protein kinase A.
Cardiovasc Res. 2006; 69(2):402-411 Doi: 10.1016/j.cardiores.2005.10.015 [OPEN ACCESS]
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2005

Guthmann, F; Wissel, H; Schachtrup, C; Tolle, A; Rudiger, M; Spener, F; Rustow, B Inhibition of TNFalpha in vivo prevents hyperoxia-mediated activation of caspase 3 in type II cells
RESPIR RES. 2005; 6(10-11): Doi: 10.1186/1465-9921-6-10 [OPEN ACCESS]
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Hofmann, UB; Houben, R; Brocker, EB; Becker, JC Role of matrix metalloproteinases in melanoma cell invasion.
Biochimie. 2005; 87(3-4):307-314 Doi: 10.1016/j.biochi.2005.01.013
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Schicho, R; Liebmann, I; Lippe, IT Extracellular signal-regulated kinase-1 and -2 are activated by gastric luminal injury in dorsal root ganglion neurons via N-methyl-D-aspartate receptors.
NEUROSCIENCE. 2005; 134(2): 505-514. Doi: 10.1016/j.neuroscience.2005.04.021
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2004

Graziani, A; Bricko, V; Carmignani, M; Graier, WF; Groschner, K Cholesterol- and caveolin-rich membrane domains are essential for phospholipase A2-dependent EDHF formation.
CARDIOVASC RES. 2004; 64(2): 234-242. Doi: 10.1016/j.cardiores.2004.06.026 [OPEN ACCESS]
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2002

Idel, S; Ellinghaus, P; Wolfrum, C; Nofer, JR; Gloerich, J; Assmann, G; Spener, F; Seedorf, U Branched chain fatty acids induce nitric oxide-dependent apoptosis in vascular smooth muscle cells.
J Biol Chem. 2002; 277(51):49319-49325 Doi: 10.1074/jbc.M204639200 [OPEN ACCESS]
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Klinger, M; Kudlacek, O; Seidel, MG; Freissmuth, M; Sexl, V MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases.
J Biol Chem. 2002; 277(36):32490-32497 Doi: 10.1074/jbc.M200556200 [OPEN ACCESS]
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Wagner, S; Groschner, K; Mayer, B; Schmidt, K Desensitization of endothelial nitric oxide synthase by receptor agonists.
Biochem J. 2002; 364(Pt 3):863-868 Doi: 10.1042/BJ20011178 [OPEN ACCESS]
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2000

Hofmann, UB; Westphal, JR; Waas, ET; Becker, JC; Ruiter, DJ; van Muijen, GNP Coexpression of integrin alpha(v)beta3 and matrix metalloproteinase-2 (MMP-2) coincides with MMP-2 activation: correlation with melanoma progression.
J Invest Dermatol. 2000; 115(4):625-632 Doi: 10.1046/j.1523-1747.2000.00114.x [OPEN ACCESS]
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1999

Seidel, MG; Klinger, M; Freissmuth, M; Höller, C Activation of mitogen-activated protein kinase by the A(2A)-adenosine receptor via a rap1-dependent and via a p21(ras)-dependent pathway.
J Biol Chem. 1999; 274(36):25833-25841 Doi: 10.1074/jbc.274.36.25833 [OPEN ACCESS]
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1998

Hu, Y; Hochleitner, BW; Wick, G; Xu, Q Decline of shear stress-induced activation of extracellular signal-regulated kinases, but not stress-activated protein kinases, in in vitro propagated endothelial cells.
Exp Gerontol. 1998; 33(6):601-613 Doi: 10.1016/S0531-5565(98)00034-5
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Potthoff, AP; Haalck, L; Spener, F Inhibition of lipases from Chromobacterium viscosum and Rhizopus oryzae by tetrahydrolipstatin.
Biochim Biophys Acta. 1998; 1389(2):123-131 Doi: 10.1016/S0005-2760(97)00160-4
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1997

Egger, G; Kukovetz, EM; Hayn, M; Fabjan, JS Changes in the polymorphonuclear leukocyte function of blood samples induced by storage time, temperature and agitation.
J Immunol Methods. 1997; 206(1-2):61-71 Doi: 10.1016%2FS0022-1759%2897%2900085-9
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Hu, Y; Cheng, L; Hochleitner, BW; Xu, Q Activation of mitogen-activated protein kinases (ERK/JNK) and AP-1 transcription factor in rat carotid arteries after balloon injury.
Arterioscler Thromb Vasc Biol. 1997; 17(11):2808-2816 Doi: 10.1161/01.ATV.17.11.2808 [OPEN ACCESS]
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1994

Halbmayer, WM; Haushofer, A; Schön, R; Fischer, M The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects.
Blood Coagul Fibrinolysis. 1994; 5(1):51-57 Doi: 10.1097/00001721-199402000-00008
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1991

Schmidt, K; Graier, WF; Kostner, GM; Mayer, B; Böhme, E; Kukovetz, WR Oxidized low-density lipoprotein antagonizes the activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor but does not interfere with its biosynthesis.
Cell Signal. 1991; 3(4):361-367 Doi: 10.1016/0898-6568(91)90065-3
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1990

SCHMIDT, K; GRAIER, WF; KUKOVETZ, WR EDRF-formation increases cGMP-levels in cultured endothelial cells.
Adv Second Messenger Phosphoprotein Res. 1990; 24(1):455-460
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