Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: DOSE-RESPONSE RELATIONSHIP, DRUG - , . Treffer: 369

2020

Alexopoulos, SJ; Chen, SY; Brandon, AE; Salamoun, JM; Byrne, FL; Garcia, CJ; Beretta, M; Olzomer, EM; Shah, DP; Philp, AM; Hargett, SR; Lawrence, RT; Lee, B; Sligar, J; Carrive, P; Tucker, SP; Philp, A; Lackner, C; Turner, N; Cooney, GJ; Santos, WL; Hoehn, KL Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice.
Nat Commun. 2020; 11(1):2397-2397 Doi: 10.1038/s41467-020-16298-2 [OPEN ACCESS]
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Isayama, T; Mildenhall, L; Schmölzer, GM; Kim, HS; Rabi, Y; Ziegler, C; Liley, HG; INTERNATIONAL LIAISON COMMITTEE ON RESUSCITATION NEWBORN LIFE SUPPORT TASK FORCE The Route, Dose, and Interval of Epinephrine for Neonatal Resuscitation: A Systematic Review.
Pediatrics. 2020; 146(4): Doi: 10.1542/peds.2020-0586
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2019

Lechleitner, M; Clodi, M; Abrahamian, H; Brath, H; Brix, J; Drexel, H; Fasching, P; Föger, B; Francesconi, C; Fröhlich-Reiterer, E; Harreiter, J; Hofer, SE; Hoppichler, F; Huber, J; Kaser, S; Kautzky-Willer, A; Ludvik, B; Luger, A; Mader, JK; Paulweber, B; Pieber, T; Prager, R; Rami-Merhar, B; Resl, M; Riedl, M; Roden, M; Saely, CH; Schelkshorn, C; Schernthaner, G; Sourij, H; Stechemesser, L; Stingl, H; Toplak, H; Wascher, TC; Weitgasser, R; Winhofer-Stöckl, Y; Zlamal-Fortunat, S [Insulin therapy of type 2 diabetes mellitus (Update 2019)].
Wien Klin Wochenschr. 2019; 131(Suppl 1):39-46 Doi: 10.1007/s00508-019-1492-7
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Tomaniak, M; Chichareon, P; Onuma, Y; Deliargyris, EN; Takahashi, K; Kogame, N; Modolo, R; Chang, CC; Rademaker-Havinga, T; Storey, RF; Dangas, GD; Bhatt, DL; Angiolillo, DJ; Hamm, C; Valgimigli, M; Windecker, S; Steg, PG; Vranckx, P; Serruys, PW; GLOBAL LEADERS Trial Investigators Benefit and Risks of Aspirin in Addition to Ticagrelor in Acute Coronary Syndromes: A Post Hoc Analysis of the Randomized GLOBAL LEADERS Trial.
JAMA Cardiol. 2019; 4(11):1092-1101 Doi: 10.1001/jamacardio.2019.3355 [OPEN ACCESS]
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Traussnigg, S; Schattenberg, JM; Demir, M; Wiegand, J; Geier, A; Teuber, G; Hofmann, WP; Kremer, AE; Spreda, F; Kluwe, J; Petersen, J; Boettler, T; Rainer, F; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Fickert, P; Trauner, M; Austrian/German NAFLD-norUDCA study group Norursodeoxycholic acid versus placebo in the treatment of non-alcoholic fatty liver disease: a double-blind, randomised, placebo-controlled, phase 2 dose-finding trial.
Lancet Gastroenterol Hepatol. 2019; 4(10):781-793 Doi: 10.1016/S2468-1253(19)30184-0
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2018

Aygören-Pürsün, E; Bygum, A; Grivcheva-Panovska, V; Magerl, M; Graff, J; Steiner, UC; Fain, O; Huissoon, A; Kinaciyan, T; Farkas, H; Lleonart, R; Longhurst, HJ; Rae, W; Triggiani, M; Aberer, W; Cancian, M; Zanichelli, A; Smith, WB; Baeza, ML; Du-Thanh, A; Gompels, M; Gonzalez-Quevedo, T; Greve, J; Guilarte, M; Katelaris, C; Dobo, S; Cornpropst, M; Clemons, D; Fang, L; Collis, P; Sheridan, W; Maurer, M; Cicardi, M Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema.
NEW ENGL J MED. 2018; 379(4): 352-362. Doi: 10.1056/NEJMoa1716995 [OPEN ACCESS]
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Katanić, J; Pferschy-Wenzig, EM; Mihailović, V; Boroja, T; Pan, SP; Nikles, S; Kretschmer, N; Rosić, G; Selaković, D; Joksimović, J; Bauer, R Phytochemical analysis and anti-inflammatory effects of Filipendula vulgaris Moench extracts.
Food Chem Toxicol. 2018; 122(11):151-162 Doi: 10.1016/j.fct.2018.10.001
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Kukolj, T; Trivanović, D; Djordjević, IO; Mojsilović, S; Krstić, J; Obradović, H; Janković, S; Santibanez, JF; Jauković, A; Bugarski, D Lipopolysaccharide can modify differentiation and immunomodulatory potential of periodontal ligament stem cells via ERK1,2 signaling.
J Cell Physiol. 2018; 233(1): 447-462. Doi: 10.1002/jcp.25904
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Leonardi, C; Maari, C; Philipp, S; Goldblum, O; Zhang, L; Burkhardt, N; Ball, S; Mallbris, L; Gonzalez, P; Fernández-Peñas, P; Puig, L Maintenance of skin clearance with ixekizumab treatment of psoriasis: Three-year results from the UNCOVER-3 study.
J Am Acad Dermatol. 2018; 79(5):824-830 Doi: 10.1016/j.jaad.2018.05.032
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Mohsin, NU; Seebacher, W; Faist, J; Hochegger, P; Kaiser, M; Mäser, P; Belaj, F; Saf, R; Kretschmer, N; Alajlani, M; Turek, I; Brantner, A; Bauer, R; Bucar, F; Weis, R Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities.
Eur J Med Chem. 2018; 143(8):97-106 Doi: 10.1016/j.ejmech.2017.11.025
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Obeid, R; Schön, C; Wilhelm, M; Pietrzik, K; Pilz, S The effectiveness of daily supplementation with 400 or 800 µg/day folate in reaching protective red blood folate concentrations in non-pregnant women: a randomized trial.
Eur J Nutr. 2018; 57(5):1771-1780 Doi: 10.1007/s00394-017-1461-8 [OPEN ACCESS]
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2017

Bondarenko, AI; Montecucco, F; Panasiuk, O; Sagach, V; Sidoryak, N; Brandt, KJ; Mach, F GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na+-Ca2+ exchanger and endoplasmic reticulum Ca2+ refilling.
Vascul Pharmacol. 2017; 89(2):39-48 Doi: 10.1016/j.vph.2017.01.002 [OPEN ACCESS]
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Davies, M; Pieber, TR; Hartoft-Nielsen, ML; Hansen, OKH; Jabbour, S; Rosenstock, J Effect of Oral Semaglutide Compared With Placebo and Subcutaneous Semaglutide on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial.
JAMA. 2017; 318(15):1460-1470 Doi: 10.1001/jama.2017.14752 [OPEN ACCESS]
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Donnerer, J; Liebmann, I Effects of Allyl Isothiocyanate, Acetaminophen, and Dipyrone in the Guinea-Pig Ileum.
PHARMACOLOGY. 2017; 99(1-2): 79-83. Doi: 10.1159/000452164
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Fickert, P; Hirschfield, GM; Denk, G; Marschall, HU; Altorjay, I; Färkkilä, M; Schramm, C; Spengler, U; Chapman, R; Bergquist, A; Schrumpf, E; Nevens, F; Trivedi, P; Reiter, FP; Tornai, I; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Trauner, M; European PSC norUDCA Study Group norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis.
J Hepatol. 2017; 67(3):549-558 Doi: 10.1016/j.jhep.2017.05.009 [OPEN ACCESS]
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Halb, L; Amann, BJ; Bornemann-Cimenti, H [Use of intracutaneous or subcutaneous botulinum toxin for postherpetic neuralgia].
Nervenarzt. 2017; 88(4):408-414 Doi: 10.1007/s00115-016-0250-6 [OPEN ACCESS]
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Hasun, M; Dörler, J; Edlinger, M; Alber, H; Von Lewinski, D; Eber, B; Roithinger, FX; Berger, R; Siostrzonek, P; Grimm, G; Benzer, W; Wintersteller, W; Huber, K; Schuchlenz, H; Weidinger, F; Austrian Acute PCI Investigators In-Hospital Outcome Comparing Bivalirudin to Heparin in Real-World Primary Percutaneous Coronary Intervention.
Am J Cardiol. 2017; 120(12):2135-2140 Doi: 10.1016/j.amjcard.2017.08.037
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Hawlitschka, A; Holzmann, C; Witt, S; Spiewok, J; Neumann, AM; Schmitt, O; Wree, A; Antipova, V Intrastriatally injected botulinum neurotoxin-A differently effects cholinergic and dopaminergic fibers in C57BL/6 mice.
Brain Res. 2017; 1676(6):46-56 Doi: 10.1016/j.brainres.2017.09.016
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Lebl, R; Thonhofer, M; Tysoe, C; Pabst, BM; Schalli, M; Weber, P; Paschke, E; Stütz, AE; Tschernutter, M; Windischhofer, W; Withers, SG A Morita-Baylis-Hillman based route to C-5a-chain-extended 4-epi-isofagomine type glycosidase inhibitors.
Carbohydr Res. 2017; 442(15):31-40 Doi: 10.1016/j.carres.2017.03.003
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Lin, S; Hoffmann, K; Gao, C; Petrulionis, M; Herr, I; Schemmer, P Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma.
J PINEAL RES. 2017; 62(3): Doi: 10.1111/jpi.12398
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Madreiter-Sokolowski, CT; Sokolowski, AA; Graier, WF Dosis Facit Sanitatem-Concentration-Dependent Effects of Resveratrol on Mitochondria.
Nutrients. 2017; 9(10): Doi: 10.3390/nu9101117 [OPEN ACCESS]
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Majali-Martinez, A; Velicky, P; Pollheimer, J; Knöfler, M; Yung, HW; Burton, GJ; Tabrizi-Wizsy, NG; Lang, U; Hiden, U; Desoye, G; Dieber-Rotheneder, M Endothelin-1 down-regulates matrix metalloproteinase 14 and 15 expression in human first trimester trophoblasts via endothelin receptor type B.
Hum Reprod. 2017; 32(1):46-54 Doi: 10.1093/humrep/dew295 [OPEN ACCESS]
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Minto, C; Vecchio, MG; Lamprecht, M; Gregori, D Definition of a tolerable upper intake level of niacin: a systematic review and meta-analysis of the dose-dependent effects of nicotinamide and nicotinic acid supplementation.
Nutr Rev. 2017; 75(6):471-490 Doi: 10.1093/nutrit/nux011
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Moser, O; Tschakert, G; Mueller, A; Groeschl, W; Pieber, TR; Koehler, G; Eckstein, ML; Bracken, RM; Hofmann, P Atypical blood glucose response to continuous and interval exercise in a person with type 1 diabetes: a case report.
J Med Case Rep. 2017; 11(1):176-176 Doi: 10.1186/s13256-017-1355-7 (- Case Report) [OPEN ACCESS]
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Pabinger, I; Fries, D; Schöchl, H; Streif, W; Toller, W Tranexamic acid for treatment and prophylaxis of bleeding and hyperfibrinolysis.
Wien Klin Wochenschr. 2017; 129(9-10):303-316 Doi: 10.1007/s00508-017-1194-y [OPEN ACCESS]
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Palkovits, S; Seidel, G; Pertl, L; Malle, EM; Hausberger, S; Makk, J; Singer, C; Osterholt, J; Herzog, SA; Haas, A; Weger, M MACULAR CHOROIDAL VOLUME CHANGES AFTER INTRAVITREAL BEVACIZUMAB FOR EXUDATIVE AGE-RELATED MACULAR DEGENERATION.
Retina. 2017; 37(12):2262-2268 Doi: 10.1097/IAE.0000000000001480
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Pilz, S; Hahn, A; Schön, C; Wilhelm, M; Obeid, R Effect of Two Different Multimicronutrient Supplements on Vitamin D Status in Women of Childbearing Age: A Randomized Trial.
Nutrients. 2017; 9(1): Doi: 10.3390/nu9010030 [OPEN ACCESS]
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Ruiz-Santaquiteria, M; Sánchez-Murcia, PA; Toro, MA; de Lucio, H; Gutiérrez, KJ; de Castro, S; Carneiro, FAC; Gago, F; Jiménez-Ruiz, A; Camarasa, MJ; Velázquez, S First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity.
Eur J Med Chem. 2017; 135(19):49-59 Doi: 10.1016/j.ejmech.2017.04.020 [OPEN ACCESS]
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Tiffner, K; Boulgaropoulos, B; Höfferer, C; Birngruber, T; Porksen, N; Linnebjerg, H; Garhyan, P; Lam, ECQ; Knadler, MP; Pieber, TR; Sinner, F Quantification of Basal Insulin Peglispro and Human Insulin in Adipose Tissue Interstitial Fluid by Open-Flow Microperfusion.
Diabetes Technol Ther. 2017; 19(5):305-314 Doi: 10.1089/dia.2016.0384
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Wallner, M; Khafaga, M; Kolesnik, E; Vafiadis, A; Schwantzer, G; Eaton, DM; Curcic, P; Köstenberger, M; Knez, I; Rainer, PP; Pichler, M; Pieske, B; Lewinski, DV Istaroxime, a potential anticancer drug in prostate cancer, exerts beneficial functional effects in healthy and diseased human myocardium.
Oncotarget. 2017; 8(30):49264-49274 Doi: 10.18632/oncotarget.17540 [OPEN ACCESS]
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Zhang, J; Li, Y; Li, G; Ma, X; Wang, H; Goswami, N; Hinghofer-Szalkay, H; Chang, H; Gao, Y Identification of the optimal dose and calpain system regulation of tetramethylpyrazine on the prevention of skeletal muscle atrophy in hindlimb unloading rats.
Biomed Pharmacother. 2017; 96(10):513-523 Doi: 10.1016/j.biopha.2017.10.012
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2016

Abrahamian, H; Kautzky-Willer, A; Rießland-Seifert, A; Fasching, P; Ebenbichler, C; Hofmann, P; Toplak, H [Mental disorders and diabetes mellitus].
Wien Klin Wochenschr. 2016; 128 Suppl 2(4):S170-S178 Doi: 10.1007/s00508-015-0939-8 [OPEN ACCESS]
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Alesutan, I; Feger, M; Tuffaha, R; Castor, T; Musculus, K; Buehling, SS; Heine, CL; Kuro-O, M; Pieske, B; Schmidt, K; Tomaschitz, A; Maerz, W; Pilz, S; Meinitzer, A; Voelkl, J; Lang, F Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine.
Cardiovasc Res. 2016; 110(3):408-418 Doi: 10.1093/cvr/cvw062 [OPEN ACCESS]
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Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591 Doi: 10.1159/000441849
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Bethel, MA; Harrison, P; Sourij, H; Sun, Y; Tucker, L; Kennedy, I; White, S; Hill, L; Oulhaj, A; Coleman, RL; Holman, RR Randomized controlled trial comparing impact on platelet reactivity of twice-daily with once-daily aspirin in people with Type 2 diabetes.
Diabet Med. 2016; 33(2):224-230 Doi: 10.1111/dme.12828
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Bosche, B; Molcanyi, M; Noll, T; Rej, S; Zatschler, B; Doeppner, TR; Hescheler, J; Müller, DJ; Macdonald, RL; Härtel, FV A differential impact of lithium on endothelium-dependent but not on endothelium-independent vessel relaxation.
Prog Neuropsychopharmacol Biol Psychiatry. 2016; 67(4):98-106 Doi: 10.1016/j.pnpbp.2016.02.004
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Clodi, M; Abrahamian, H; Drexel, H; Fasching, P; Föger, B; Francesconi, C; Hoppichler, F; Kaser, S; Kautzky-Willer, A; Lechleitner, M; Ludvik, B; Prager, R; Fröhlich-Reiterer, E; Roden, M; Säly, C; Schernthaner, G; Sourij, H; Toplak, H; Wascher, TC; Weitgasser, R [Antihyperglycemic treatment guidelines for diabetes mellitus type 2].
Wien Klin Wochenschr. 2016; 128 Suppl 2(4):S45-S53 Doi: 10.1007/s00508-016-0991-z [OPEN ACCESS]
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Dejaco, C; Matteson, EL; Buttgereit, F Diagnostics and treatment of polymyalgia rheumatica].
Z Rheumatol. 2016; 75(7):687-700 Doi: 10.1007/s00393-016-0105-3
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Díez-Dacal, B; Sánchez-Gómez, FJ; Sánchez-Murcia, PA; Milackova, I; Zimmerman, T; Ballekova, J; García-Martín, E; Agúndez, JA; Gharbi, S; Gago, F; Stefek, M; Pérez-Sala, D Molecular Interactions and Implications of Aldose Reductase Inhibition by PGA1 and Clinically Used Prostaglandins.
Mol Pharmacol. 2016; 89(1):42-52 Doi: 10.1124/mol.115.100693 [OPEN ACCESS]
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Eder, C; Schenk, S; Trifinopoulos, J; Külekci, B; Kienzl, M; Schildböck, S; Ogon, M Does intrawound application of vancomycin influence bone healing in spinal surgery?
Eur Spine J. 2016; 25(4): 1021-1028. Doi: 10.1007/s00586-015-3943-9
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Eigentler, TK; Gutzmer, R; Hauschild, A; Heinzerling, L; Schadendorf, D; Nashan, D; Hölzle, E; Kiecker, F; Becker, J; Sunderkötter, C; Moll, I; Richtig, E; Pönitzsch, I; Pehamberger, H; Kaufmann, R; Pföhler, C; Vogt, T; Berking, C; Praxmarer, M; Garbe, C; Dermatologic Cooperative Oncology Group (DeCOG) Adjuvant treatment with pegylated interferon α-2a versus low-dose interferon α-2a in patients with high-risk melanoma: a randomized phase III DeCOG trial.
Ann Oncol. 2016; 27(8):1625-1632 Doi: 10.1093/annonc/mdw225 [OPEN ACCESS]
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Ewig, S; Höffken, G; Kern, WV; Rohde, G; Flick, H; Krause, R; Ott, S; Bauer, T; Dalhoff, K; Gatermann, S; Kolditz, M; Krüger, S; Lorenz, J; Pletz, M; de Roux, A; Schaaf, B; Schaberg, T; Schütte, H; Welte, T [Management of Adult Community-acquired Pneumonia and Prevention - Update 2016].
Pneumologie. 2016; 70(3):151-200 Doi: 10.1055/s-0042-101873
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Fabian, E; Bordag, N; Herold, M; Kamp, H; Krennrich, G; Looser, R; Ma-Hock, L; Mellert, W; Montoya, G; Peter, E; Prokudin, A; Spitzer, M; Strauss, V; Walk, T; Zbranek, R; van Ravenzwaay, B Metabolite profiles of rats in repeated dose toxicological studies after oral and inhalative exposure.
Toxicol Lett. 2016; 255: 11-23. Doi: 10.1016/j.toxlet.2016.05.003
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Fan, P; Liu, L; Yin, Y; Zhao, Z; Zhang, Y; Amponsah, PS; Xiao, X; Bauer, N; Abukiwan, A; Nwaeburu, CC; Gladkich, J; Gao, C; Schemmer, P; Gross, W; Herr, I MicroRNA-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer.
Cancer Lett. 2016; 373(1):130-137 Doi: 10.1016/j.canlet.2016.01.038
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Goldinger, SM; Gobbi Bischof, S; Fink-Puches, R; Klemke, CD; Dréno, B; Bagot, M; Dummer, R Efficacy and Safety of APO866 in Patients With Refractory or Relapsed Cutaneous T-Cell Lymphoma: A Phase 2 Clinical Trial.
JAMA Dermatol. 2016; 152(7):837-839 Doi: 10.1001/jamadermatol.2016.0401 [OPEN ACCESS]
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Holman, RR; Bethel, MA; George, J; Sourij, H; Doran, Z; Keenan, J; Khurmi, NS; Mentz, RJ; Oulhaj, A; Buse, JB; Chan, JC; Iqbal, N; Kundu, S; Maggioni, AP; Marso, SP; Öhman, P; Pencina, MJ; Poulter, N; Porter, LE; Ramachandran, A; Zinman, B; Hernandez, AF Rationale and design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial.
Am Heart J. 2016; 174(6):103-110 Doi: 10.1016/j.ahj.2015.12.009 [OPEN ACCESS]
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Khan, AA; Morrison, A; Kendler, DL; Rizzoli, R; Hanley, DA; Felsenberg, D; McCauley, LK; O'Ryan, F; Reid, IR; Ruggiero, SL; Taguchi, A; Tetradis, S; Watts, NB; Brandi, ML; Peters, E; Guise, T; Eastell, R; Cheung, AM; Morin, SN; Masri, B; Cooper, C; Morgan, SL; Obermayer-Pietsch, B; Langdahl, BL; Dabagh, RA; Davison, KS; Sándor, GK; Josse, RG; Bhandari, M; El Rabbany, M; Pierroz, DD; Sulimani, R; Saunders, DP; Brown, JP; Compston, J; International Task Force on Osteonecrosis of the Jaw Case-Based Review of Osteonecrosis of the Jaw (ONJ) and Application of the International Recommendations for Management From the International Task Force on ONJ.
J Clin Densitom. 2016; 20(1):8-24 Doi: 10.1016/j.jocd.2016.09.005
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Kollerits, B; Drechsler, C; Krane, V; Lamina, C; März, W; Dieplinger, H; Ritz, E; Wanner, C; Kronenberg, F; German Diabetes and Dialysis Study Investigators Lipoprotein(a) concentrations, apolipoprotein(a) isoforms and clinical endpoints in haemodialysis patients with type 2 diabetes mellitus: results from the 4D Study.
Nephrol Dial Transplant. 2016; 31(11):1901-1908 Doi: 10.1093/ndt/gfv428 [OPEN ACCESS]
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Mader, JK; Jensen, L; Ingwersen, SH; Christiansen, E; Heller, S; Pieber, TR Pharmacokinetic Properties of Liraglutide as Adjunct to Insulin in Subjects with Type 1 Diabetes Mellitus.
Clin Pharmacokinet. 2016; 55(11):1457-1463 Doi: 10.1007/s40262-016-0413-4 [OPEN ACCESS]
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Mayr, C; Wagner, A; Loeffelberger, M; Bruckner, D; Jakab, M; Berr, F; Di Fazio, P; Ocker, M; Neureiter, D; Pichler, M; Kiesslich, T The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells.
Oncotarget. 2016; 7(1):745-758 Doi: 10.18632/oncotarget.6378 [OPEN ACCESS]
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