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Publikationen

Suchbegriffe: DISEASE MODELS, ANIMAL - , . Treffer: 465

2021

Sistilli, G; Kalendova, V; Cajka, T; Irodenko, I; Bardova, K; Oseeva, M; Zacek, P; Kroupova, P; Horakova, O; Lackner, K; Gastaldelli, A; Kuda, O; Kopecky, J; Rossmeisl, M Krill Oil Supplementation Reduces Exacerbated Hepatic Steatosis Induced by Thermoneutral Housing in Mice with Diet-Induced Obesity.
NUTRIENTS. 2021; 13(2): Doi: 10.3390/nu13020437 [OPEN ACCESS]
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2020

Alexopoulos, SJ; Chen, SY; Brandon, AE; Salamoun, JM; Byrne, FL; Garcia, CJ; Beretta, M; Olzomer, EM; Shah, DP; Philp, AM; Hargett, SR; Lawrence, RT; Lee, B; Sligar, J; Carrive, P; Tucker, SP; Philp, A; Lackner, C; Turner, N; Cooney, GJ; Santos, WL; Hoehn, KL Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice.
Nat Commun. 2020; 11(1):2397-2397 Doi: 10.1038/s41467-020-16298-2 [OPEN ACCESS]
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Fickert, P; Rosenkranz, AR Cholemic Nephropathy Reloaded.
Semin Liver Dis. 2020; 40(1):91-100 Doi: 10.1055/s-0039-1698826 [OPEN ACCESS]
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Kasatkina, LA; Heinemann, A; Hudz, YA; Thomas, D; Sturm, EM Stearoylethanolamide interferes with retrograde endocannabinoid signalling and supports the blood-brain barrier integrity under acute systemic inflammation.
Biochem Pharmacol. 2020; 174(1):113783-113783 Doi: 10.1016/j.bcp.2019.113783
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Rambach, G; Fleischer, V; Harpf, V; Lackner, M; Meinitzer, A; Maier, H; Engesser, J; Lass-Flörl, C; Speth, C Comparative immunopathogenesis in a murine model of inhalative infection with the mucormycetes Lichtheimia corymbifera and Rhizopus arrhizus.
PLOS ONE. 2020; 15(6): e0234063-e0234063. Doi: 10.1371/journal.pone.0234063 [OPEN ACCESS]
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Szostaczuk, N; van Schothorst, EM; Sánchez, J; Priego, T; Palou, M; Bekkenkamp-Grovenstein, M; Faustmann, G; Obermayer-Pietsch, B; Tiran, B; Roob, JM; Winklhofer-Roob, BM; Keijer, J; Palou, A; Picó, C Identification of blood cell transcriptome-based biomarkers in adulthood predictive of increased risk to develop metabolic disorders using early life intervention rat models.
FASEB J. 2020; 34(7):9003-9017 Doi: 10.1096/fj.202000071RR
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2019

Bidola, P; Martins de Souza E Silva, J; Achterhold, K; Munkhbaatar, E; Jost, PJ; Meinhardt, AL; Taphorn, K; Zdora, MC; Pfeiffer, F; Herzen, J A step towards valid detection and quantification of lung cancer volume in experimental mice with contrast agent-based X-ray microtomography.
Sci Rep. 2019; 9(1):1325-1325 Doi: 10.1038/s41598-018-37394-w [OPEN ACCESS]
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Fickert, P; Wagner, M Preface - Animal models in liver disease.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(5):867-868 Doi: 10.1016/j.bbadis.2019.02.004 [OPEN ACCESS]
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Kargl, J; Zhu, X; Zhang, H; Yang, GHY; Friesen, TJ; Shipley, M; Maeda, DY; Zebala, JA; McKay-Fleisch, J; Meredith, G; Mashadi-Hossein, A; Baik, C; Pierce, RH; Redman, MW; Thompson, JC; Albelda, SM; Bolouri, H; Houghton, AM Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC.
JCI Insight. 2019; 4(24): Doi: 10.1172/jci.insight.130850 [OPEN ACCESS]
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Pipper, C; Bordag, N; Reiter, B; Economides, K; Florian, P; Birngruber, T; Sinner, F; Bodenlenz, M; Eberl, A LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation.
J Lipid Res. 2019; 60(4):758-766 Doi: 10.1194/jlr.M087221 [OPEN ACCESS]
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Primessnig, U; Bracic, T; Levijoki, J; Otsomaa, L; Pollesello, P; Falcke, M; Pieske, B; Heinzel, FR Long-term effects of Na⁺ /Ca²⁺ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction.
Eur J Heart Fail. 2019; 21(12):1543-1552 Doi: 10.1002/ejhf.1619 [OPEN ACCESS]
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Strell, C; Paulsson, J; Jin, SB; Tobin, NP; Mezheyeuski, A; Roswall, P; Mutgan, C; Mitsios, N; Johansson, H; Wickberg, SM; Svedlund, J; Nilsson, M; Hall, P; Mulder, J; Radisky, DC; Pietras, K; Bergh, J; Lendahl, U; Wärnberg, F; Östman, A Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ.
J Natl Cancer Inst. 2019; 111(9):983-995 Doi: 10.1093/jnci/djy234 [OPEN ACCESS]
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Willecke, F; Rupprecht, B; Gissler, MC; Pfeiffer, K; Anto-Michel, N; Stachon, P; Wolf, D; Hilgendorf, I; Hoppe, N; Bode, C; Zirlik, A Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation.
J Vasc Res. 2019; 56(6):308-319 Doi: 10.1159/000501615
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2018

Aringer, I; Artinger, K; Kirsch, AH; Schabhüttl, C; Jandl, K; Bärnthaler, T; Mooslechner, AA; Herzog, SA; Uhlig, M; Kirsch, A; Frank, S; Banas, M; Pollheimer, M; Eller, P; Rosenkranz, AR; Heinemann, A; Eller, K Blockade of prostaglandin E₂ receptor 4 ameliorates nephrotoxic serum nephritis.
Am J Physiol Renal Physiol. 2018; 315(6):F1869-F1880 Doi: 10.1152/ajprenal.00113.2018 [OPEN ACCESS]
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Basu, D; Hu, Y; Huggins, LA; Mullick, AE; Graham, MJ; Wietecha, T; Barnhart, S; Mogul, A; Pfeiffer, K; Zirlik, A; Fisher, EA; Bornfeldt, KE; Willecke, F; Goldberg, IJ Novel Reversible Model of Atherosclerosis and Regression Using Oligonucleotide Regulation of the LDL Receptor.
Circ Res. 2018; 122(4):560-567 Doi: 10.1161/CIRCRESAHA.117.311361 [OPEN ACCESS]
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De Grove, KC; Provoost, S; Braun, H; Blomme, EE; Teufelberger, AR; Krysko, O; Beyaert, R; Brusselle, GG; Joos, GF; Maes, T IL-33 signalling contributes to pollutant-induced allergic airway inflammation.
Clin Exp Allergy. 2018; 48(12): 1665-1675. Doi: 10.1111/cea.13261
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Frauscher, B; Kirsch, AH; Schabhüttl, C; Schweighofer, K; Kétszeri, M; Pollheimer, M; Dragun, D; Schröder, K; Rosenkranz, AR; Eller, K; Eller, P Autophagy Protects From Uremic Vascular Media Calcification.
Front Immunol. 2018; 9(5):1866-1866 Doi: 10.3389/fimmu.2018.01866 [OPEN ACCESS]
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Fuchs, CD; Paumgartner, G; Mlitz, V; Kunczer, V; Halilbasic, E; Leditznig, N; Wahlström, A; Ståhlman, M; Thüringer, A; Kashofer, K; Stojakovic, T; Marschall, HU; Trauner, M Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2^-/- mice by modulating composition, signalling and excretion of faecal bile acids.
Gut. 2018; 67(9):1683-1691 Doi: 10.1136/gutjnl-2017-314553 [OPEN ACCESS]
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Gugatschka, M; Jarvis, JC; Perkins, JD; Bubalo, V; Wiederstein-Grasser, I; Lanmüller, H; Gerstenberger, C; Karbiener, M Functional Electrical Stimulation Leads to Increased Volume of the Aged Thyroarytenoid Muscle.
Laryngoscope. 2018; 128(12):2852-2857 Doi: 10.1002/lary.27342 [OPEN ACCESS]
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Koentges, C; Pepin, ME; Müsse, C; Pfeil, K; Alvarez, SVV; Hoppe, N; Hoffmann, MM; Odening, KE; Sossalla, S; Zirlik, A; Hein, L; Bode, C; Wende, AR; Bugger, H Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans.
Basic Res Cardiol. 2018; 113(1):8-8 Doi: 10.1007/s00395-017-0666-6 [OPEN ACCESS]
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Krones, E; Pollheimer, MJ; Rosenkranz, AR; Fickert, P Cholemic nephropathy - Historical notes and novel perspectives.
Biochim Biophys Acta Mol Basis Dis. 2018; 1864(4 Pt B):1356-1366 Doi: 10.1016/j.bbadis.2017.08.028 [OPEN ACCESS]
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Manninger, M; Zweiker, D; van Hunnik, A; Alogna, A; Prassl, AJ; Schipke, J; Zeemering, S; Zirngast, B; Schönleitner, P; Schwarzl, M; Herbst, V; Thon-Gutschi, E; Huber, S; Rohrer, U; Ebner, J; Brussee, H; Pieske, BM; Heinzel, FR; Verheule, S; Antoons, G; Lueger, A; Mühlfeld, C; Plank, G; Schotten, U; Post, H; Scherr, D Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation.
Heart Rhythm. 2018; 15(9):1328-1336 Doi: 10.1016/j.hrthm.2018.05.016
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Tang, Y; Blomenkamp, KS; Fickert, P; Trauner, M; Teckman, JH NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.
PLoS One. 2018; 13(8):e0200897-e0200897 Doi: 10.1371/journal.pone.0200897 [OPEN ACCESS]
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Teufelberger, AR; Nordengrün, M; Braun, H; Maes, T; De Grove, K; Holtappels, G; O'Brien, C; Provoost, S; Hammad, H; Gonçalves, A; Beyaert, R; Declercq, W; Vandenabeele, P; Krysko, DV; Bröker, BM; Bachert, C; Krysko, O The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D.
J Allergy Clin Immunol. 2018; 141(2): 549-559. Doi: 10.1016/j.jaci.2017.05.004
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2017

Aass, T; Stangeland, L; Chambers, DJ; Hallström, S; Rossmann, C; Podesser, BK; Urban, M; Nesheim, K; Haaverstad, R; Matre, K; Grong, K Myocardial energy metabolism and ultrastructure with polarizing and depolarizing cardioplegia in a porcine model.
Eur J Cardiothorac Surg. 2017; 52(1):180-188 Doi: 10.1093/ejcts/ezx035 [OPEN ACCESS]
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Amankulor, NM; Kim, Y; Arora, S; Kargl, J; Szulzewsky, F; Hanke, M; Margineantu, DH; Rao, A; Bolouri, H; Delrow, J; Hockenbery, D; Houghton, AM; Holland, EC Mutant IDH1 regulates the tumor-associated immune system in gliomas.
Genes Dev. 2017; 31(8):774-786 Doi: 10.1101/gad.294991.116 [OPEN ACCESS]
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Artinger, K; Kirsch, AH; Aringer, I; Moschovaki-Filippidou, F; Eller, P; Rosenkranz, AR; Eller, K Innate and adaptive immunity in experimental glomerulonephritis: a pathfinder tale.
Pediatr Nephrol. 2017; 32(6):943-947 Doi: 10.1007/s00467-016-3404-7 [OPEN ACCESS]
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Barabino, S; Horwath-Winter, J; Messmer, EM; Rolando, M; Aragona, P; Kinoshita, S The role of systemic and topical fatty acids for dry eye treatment.
Prog Retin Eye Res. 2017; 61(1):23-34 Doi: 10.1016/j.preteyeres.2017.05.003
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Bast, A; Kubis, H; Holtfreter, B; Ribback, S; Martin, H; Schreiner, HC; Dominik, MJ; Breitbach, K; Dombrowski, F; Kocher, T; Steinmetz, I NADPH Oxidase Contributes to Resistance against Aggregatibacter actinomycetemcomitans-Induced Periodontitis in Mice.
Infect Immun. 2017; 85(2): Doi: 10.1128/IAI.00849-16 [OPEN ACCESS]
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Biasin, V; Wygrecka, M; Marsh, LM; Becker-Pauly, C; Brcic, L; Ghanim, B; Klepetko, W; Olschewski, A; Kwapiszewska, G Meprin β contributes to collagen deposition in lung fibrosis.
Sci Rep. 2017; 7(1):39969-39969 Doi: 10.1038/srep39969 [OPEN ACCESS]
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Bürger, C; Shirsath, N; Lang, V; Diehl, S; Kaufmann, R; Weigert, A; Han, YY; Ringel, C; Wolf, P Blocking mTOR Signalling with Rapamycin Ameliorates Imiquimod-induced Psoriasis in Mice.
Acta Derm Venereol. 2017; 97(9):1087-1094 Doi: 10.2340/00015555-2724 [OPEN ACCESS]
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Castellani, C; Singer, G; Kaiser, M; Kaiser, T; Huang, J; Sperl, D; Kashofer, K; Fauler, G; Guertl-Lackner, B; Höfler, G; Till, H Neuroblastoma causes alterations of the intestinal microbiome, gut hormones, inflammatory cytokines, and bile acid composition.
Pediatr Blood Cancer. 2017; 64(8): Doi: 10.1002/pbc.26425
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Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 Doi: 10.1002/1873-3468.12845 [OPEN ACCESS]
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Hawlitschka, A; Holzmann, C; Witt, S; Spiewok, J; Neumann, AM; Schmitt, O; Wree, A; Antipova, V Intrastriatally injected botulinum neurotoxin-A differently effects cholinergic and dopaminergic fibers in C57BL/6 mice.
Brain Res. 2017; 1676(6):46-56 Doi: 10.1016/j.brainres.2017.09.016
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Hu, Y; Yibrehu, B; Zabini, D; Kuebler, WM Animal models of sarcoidosis.
Cell Tissue Res. 2017; 367(3):651-661 Doi: 10.1007/s00441-016-2526-3
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Kaineder, K; Birngruber, T; Rauter, G; Obermüller, B; Eichler, J; Münzker, J; Al-Zoughbi, W; Mautner, SI; Torekov, SS; Hartmann, B; Kotzbeck, P; Pieber, TR Chronic intrahypothalamic rather than subcutaneous liraglutide treatment reduces body weight gain and stimulates the melanocortin receptor system.
Int J Obes (Lond). 2017; 41(8):1263-1270 Doi: 10.1038/ijo.2017.98 [OPEN ACCESS]
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Katira, BH; Giesinger, RE; Engelberts, D; Zabini, D; Kornecki, A; Otulakowski, G; Yoshida, T; Kuebler, WM; McNamara, PJ; Connelly, KA; Kavanagh, BP Adverse Heart-Lung Interactions in Ventilator-induced Lung Injury.
Am J Respir Crit Care Med. 2017; 196(11):1411-1421 Doi: 10.1164/rccm.201611-2268OC
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Kintz, E; Heiss, C; Black, I; Donohue, N; Brown, N; Davies, MR; Azadi, P; Baker, S; Kaye, PM; van der Woude, M Salmonella enterica Serovar Typhi Lipopolysaccharide O-Antigen Modification Impact on Serum Resistance and Antibody Recognition.
Infect Immun. 2017; 85(4): Doi: 10.1128/IAI.01021-16 [OPEN ACCESS]
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Kromrey, ML; Göhler, A; Friedrich, N; Kindermann, K; Hadlich, S; Puls, D; Steinmetz, I; Kühn, JP Monitoring of abdominal Staphylococcus aureus infection using magnetic resonance imaging: a murine animal model for hepatic and renal abscesses.
Eur J Clin Microbiol Infect Dis. 2017; 36(2): 373-378. Doi: 10.1007/s10096-016-2811-9
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Lubitz, AL; Sjoholm, LO; Goldberg, A; Pathak, A; Santora, T; Sharp, TE; Wallner, M; Berretta, RM; Poole, LA; Wu, J; Wolfson, MR Acute right heart failure after hemorrhagic shock and trauma pneumonectomy-a management approach: A blinded randomized controlled animal trial using inhaled nitric oxide.
J Trauma Acute Care Surg. 2017; 82(2):243-251 Doi: 10.1097/TA.0000000000001325 [OPEN ACCESS]
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Lunova, M; Schwarz, P; Nuraldeen, R; Levada, K; Kuscuoglu, D; Stützle, M; Vujić Spasić, M; Haybaeck, J; Ruchala, P; Jirsa, M; Deschemin, JC; Vaulont, S; Trautwein, C; Strnad, P Hepcidin knockout mice spontaneously develop chronic pancreatitis owing to cytoplasmic iron overload in acinar cells.
J Pathol. 2017; 241(1):104-114 Doi: 10.1002/path.4822 [OPEN ACCESS]
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Mayerhofer, R; Fröhlich, EE; Reichmann, F; Farzi, A; Kogelnik, N; Fröhlich, E; Sattler, W; Holzer, P Diverse action of lipoteichoic acid and lipopolysaccharide on neuroinflammation, blood-brain barrier disruption, and anxiety in mice.
Brain Behav Immun. 2017; 60(3):174-187 Doi: 10.1016/j.bbi.2016.10.011 [OPEN ACCESS]
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Reinisch, A; Hernandez, DC; Schallmoser, K; Majeti, R Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice.
Nat Protoc. 2017; 12(10): 2169-2188. Doi: 10.1038/nprot.2017.088 [OPEN ACCESS]
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Schrumpf, E; Jiang, X; Zeissig, S; Pollheimer, MJ; Anmarkrud, JA; Tan, C; Exley, MA; Karlsen, TH; Blumberg, RS; Melum, E The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation.
Physiol Rep. 2017; 5(4): Doi: 10.14814/phy2.13117 [OPEN ACCESS]
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Schuoler, C; Haider, TJ; Leuenberger, C; Vogel, J; Ostergaard, L; Kwapiszewska, G; Kohler, M; Gassmann, M; Huber, LC; Brock, M Aquaporin 1 controls the functional phenotype of pulmonary smooth muscle cells in hypoxia-induced pulmonary hypertension.
Basic Res Cardiol. 2017; 112(3): 30-30. Doi: 10.1007/s00395-017-0620-7 [OPEN ACCESS]
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Sharp, TE; Schena, GJ; Hobby, AR; Starosta, T; Berretta, RM; Wallner, M; Borghetti, G; Gross, P; Yu, D; Johnson, J; Feldsott, E; Trappanese, DM; Toib, A; Rabinowitz, JE; George, JC; Kubo, H; Mohsin, S; Houser, SR Cortical Bone Stem Cell Therapy Preserves Cardiac Structure and Function After Myocardial Infarction.
Circ Res. 2017; 121(11):1263-1278 Doi: 10.1161/CIRCRESAHA.117.311174 [OPEN ACCESS]
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Tanna, P; Strauss, RW; Fujinami, K; Michaelides, M Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options.
Br J Ophthalmol. 2017; 101(1): 25-30. Doi: 10.1136/bjophthalmol-2016-308823 [OPEN ACCESS]
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Toib, A; Zhang, C; Borghetti, G; Zhang, X; Wallner, M; Yang, Y; Troupes, CD; Kubo, H; Sharp, TE; Feldsott, E; Berretta, RM; Zalavadia, N; Trappanese, DM; Harper, S; Gross, P; Chen, X; Mohsin, S; Houser, SR Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.
Am J Physiol Heart Circ Physiol. 2017; 313(3):H620-H630 Doi: 10.1152/ajpheart.00167.2017 [OPEN ACCESS]
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Üçal, M; Haindl, MT; Adzemovic, MZ; Strasser, J; Theisl, L; Zeitelhofer, M; Kraitsy, K; Ropele, S; Schäfer, U; Fazekas, F; Hochmeister, S Widespread cortical demyelination of both hemispheres can be induced by injection of pro-inflammatory cytokines via an implanted catheter in the cortex of MOG-immunized rats.
Exp Neurol. 2017; 294(7):32-44 Doi: 10.1016/j.expneurol.2017.04.014
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Üçal, M; Kraitsy, K; Weidinger, A; Paier-Pourani, J; Patz, S; Fink, B; Molcanyi, M; Schäfer, U Comprehensive Profiling of Modulation of Nitric Oxide Levels and Mitochondrial Activity in the Injured Brain: An Experimental Study Based on the Fluid Percussion Injury Model in Rats.
J Neurotrauma. 2017; 34(2):475-486 Doi: 10.1089/neu.2016.4411
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