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Publikationen

Suchbegriffe: DEMYELINATION, . Treffer: 79

2022

Sibgatulin, R; Güllmar, D; Deistung, A; Enzinger, C; Ropele, S; Reichenbach, JR Magnetic susceptibility anisotropy in normal appearing white matter in multiple sclerosis from single-orientation acquisition.
Neuroimage Clin. 2022; 35:103059 Doi: 10.1016/j.nicl.2022.103059 [OPEN ACCESS]
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Zeitelhofer, M; Hochmeister, S; Adzemovic, MZ Editorial: Neuropathology of Autoimmune Inflammatory Demyelination Disorders
FRONT NEUROL. 2022; 13: 925216 Doi: 10.3389/fneur.2022.925216 [OPEN ACCESS]
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2021

Haindl, MT; Üçal, M; Klaus, B; Tögl, L; Dohrmann, J; Adzemovic, MZ; Enzinger, C; Hochmeister, S Anti-CD20 treatment effectively attenuates cortical pathology in a rat model of widespread cortical demyelination.
J NEUROINFLAMM. 2021; 18(1): 138 Doi: 10.1186/s12974-021-02189-w [OPEN ACCESS]
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Üçal, M; Haindl, MT; Adzemovic, MZ; Zeitelhofer, M; Schaefer, U; Fazekas, F; Hochmeister, S Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines.
J Vis Exp. 2021; Doi: 10.3791/57879
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Wiendl, H; Gold, R; Berger, T; Derfuss, T; Linker, R; Mäurer, M; Aktas, O; Baum, K; Berghoff, M; Bittner, S; Chan, A; Czaplinski, A; Deisenhammer, F; Di, Pauli, F; Du, Pasquier, R; Enzinger, C; Fertl, E; Gass, A; Gehring, K; Gobbi, C; Goebels, N; Guger, M; Haghikia, A; Hartung, HP; Heidenreich, F; Hoffmann, O; Kallmann, B; Kleinschnitz, C; Klotz, L; Leussink, VI; Leutmezer, F; Limmroth, V; Lünemann, JD; Lutterotti, A; Meuth, SG; Meyding-Lamadé, U; Platten, M; Rieckmann, P; Schmidt, S; Tumani, H; Weber, F; Weber, MS; Zettl, UK; Ziemssen, T; Zipp, F, , ‘Multiple, Sclerosis, Therapy, Consensus, Group’, (MSTCG) Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper).
Ther Adv Neurol Disord. 2021; 14: 17562864211039648 Doi: 10.1177/17562864211039648 [OPEN ACCESS]
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Wiendl, H; Gold, R; Berger, T; Derfuss, T; Linker, R; Mäurer, M; Stangel, M; Aktas, O; Baum, K; Berghoff, M; Bittner, S; Chan, A; Czaplinski, A; Deisenhammer, F; Di, Pauli, F; Du, Pasquier, R; Enzinger, C; Fertl, E; Gass, A; Gehring, K; Gobbi, C; Goebels, N; Guger, M; Haghikia, A; Hartung, HP; Heidenreich, F; Hoffmann, O; Hunter, ZR; Kallmann, B; Kleinschnitz, C; Klotz, L; Leussink, V; Leutmezer, F; Limmroth, V; Lünemann, JD; Lutterotti, A; Meuth, SG; Meyding-Lamadé, U; Platten, M; Rieckmann, P; Schmidt, S; Tumani, H; Weber, MS; Weber, F; Zettl, UK; Ziemssen, T; Zipp, F, , die, Multiple, Sklerose, Therapie, Konsensus, Gruppe, (MSTKG) [Multiple sclerosis treatment consensus group (MSTCG): position paper on disease-modifying treatment of multiple sclerosis 2021 (white paper)].
Nervenarzt. 2021; 92(8): 773-801. Doi: 10.1007/s00115-021-01157-2 [OPEN ACCESS]
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2020

Hochmeister, S; Aeinehband, S; Dorris, C; Berglund, R; Haindl, MT; Velikic, V; Gustafsson, SA; Olsson, T; Piehl, F; Jagodic, M; Zeitelhofer, M; Adzemovic, MZ Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA (Mhc2ta).
FRONT NEUROL. 2020; 11: 600401 Doi: 10.3389/fneur.2020.600401 [OPEN ACCESS]
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Hochmeister, S; Gattringer, T; Asslaber, M; Stangl, V; Haindl, MT; Enzinger, C; Höftberger, R A Fulminant Case of Demyelinating Encephalitis With Extensive Cortical Involvement Associated With Anti-MOG Antibodies.
Front Neurol. 2020; 11: 31-31. Doi: 10.3389/fneur.2020.00031 (- Case Report) [OPEN ACCESS]
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Höftberger, R; Guo, Y; Flanagan, EP; Lopez-Chiriboga, AS; Endmayr, V; Hochmeister, S; Joldic, D; Pittock, SJ; Tillema, JM; Gorman, M; Lassmann, H; Lucchinetti, CF The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody.
Acta Neuropathol. 2020; 139(5):875-892 Doi: 10.1007/s00401-020-02132-y (- Case Report) [OPEN ACCESS]
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2019

Filippi, M; Brück, W; Chard, D; Fazekas, F; Geurts, JJG; Enzinger, C; Hametner, S; Kuhlmann, T; Preziosa, P; Rovira, À; Schmierer, K; Stadelmann, C; Rocca, MA; Attendees of the Correlation between Pathological and MRI findings in MS workshop Association between pathological and MRI findings in multiple sclerosis.
LANCET NEUROL. 2019; 18(2): 198-210. Doi: 10.1016/S1474-4422(18)30451-4
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Rattay, TW; Lindig, T; Baets, J; Smets, K; Deconinck, T; Söhn, AS; Hörtnagel, K; Eckstein, KN; Wiethoff, S; Reichbauer, J; Döbler-Neumann, M; Krägeloh-Mann, I; Auer-Grumbach, M; Plecko, B; Münchau, A; Wilken, B; Janauschek, M; Giese, AK; De Bleecker, JL; Ortibus, E; Debyser, M; Lopez de Munain, A; Pujol, A; Bassi, MT; D'Angelo, MG; De Jonghe, P; Züchner, S; Bauer, P; Schöls, L; Schüle, R FAHN/SPG35: a narrow phenotypic spectrum across disease classifications.
Brain. 2019; 142(6): 1561-1572. Doi: 10.1093/brain/awz102 [OPEN ACCESS]
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2018

De Stefano, N; Giorgio, A; Tintoré, M; Pia Amato, M; Kappos, L; Palace, J; Yousry, T; Rocca, MA; Ciccarelli, O; Enzinger, C; Frederiksen, J; Filippi, M; Vrenken, H; Rovira, À; MAGNIMS study group Radiologically isolated syndrome or subclinical multiple sclerosis: MAGNIMS consensus recommendations.
Mult Scler. 2018; 24(2):214-221 Doi: 10.1177/1352458517717808
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Farinazzo, A; Angiari, S; Turano, E; Bistaffa, E; Dusi, S; Ruggieri, S; Bonafede, R; Mariotti, R; Constantin, G; Bonetti, B Nanovesicles from adipose-derived mesenchymal stem cells inhibit T lymphocyte trafficking and ameliorate chronic experimental autoimmune encephalomyelitis.
Sci Rep. 2018; 8(1): 7473-7473. Doi: 10.1038/s41598-018-25676-2 [OPEN ACCESS]
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Filippi, M; Preziosa, P; Meani, A; Ciccarelli, O; Mesaros, S; Rovira, A; Frederiksen, J; Enzinger, C; Barkhof, F; Gasperini, C; Brownlee, W; Drulovic, J; Montalban, X; Cramer, SP; Pichler, A; Hagens, M; Ruggieri, S; Martinelli, V; Miszkiel, K; Tintore, M; Comi, G; Dekker, I; Uitdehaag, B; Dujmovic-Basuroski, I; Rocca, MA Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study
LANCET NEUROL. 2018; 17(2): 133-142. Doi: 10.1016/S1474-4422(17)30469-6
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Lang, J; Biebl, A; Gruber, A; Maier-Hiebl, B; Hainfellner, JA; Höftberger, R; Gelpi, E Teaching Case 5-2018: Integrated morphological and immunological work-up of neurosurgical specimen allows accurate diagnosis of neuroinflammatory lesions: an example of acute disseminated encephalomyelitis (ADEM) associated with anti-MOG antibodies.
Clin Neuropathol. 2018; 37(5):206-208 Doi: 10.5414/NP301136 [OPEN ACCESS]
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Leitinger, M; Varosanec, MV; Pikija, S; Wass, RE; Bandke, D; Weis, S; Studnicka, M; Grinzinger, S; McCoy, MR; Hauer, L; Sellner, J Fatal Necrotizing Encephalopathy after Treatment with Nivolumab for Squamous Non-Small Cell Lung Cancer: Case Report and Review of the Literature.
Front Immunol. 2018; 9(1): 108-108. Doi: 10.3389/fimmu.2018.00108 (- Case Report) [OPEN ACCESS]
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2017

Brownlee, WJ; Hardy, TA; Fazekas, F; Miller, DH Diagnosis of multiple sclerosis: progress and challenges.
Lancet. 2017; 389(10076):1336-1346 Doi: 10.1016/S0140-6736(16)30959-X
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Üçal, M; Haindl, MT; Adzemovic, MZ; Strasser, J; Theisl, L; Zeitelhofer, M; Kraitsy, K; Ropele, S; Schäfer, U; Fazekas, F; Hochmeister, S Widespread cortical demyelination of both hemispheres can be induced by injection of pro-inflammatory cytokines via an implanted catheter in the cortex of MOG-immunized rats.
Exp Neurol. 2017; 294(7):32-44 Doi: 10.1016/j.expneurol.2017.04.014
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2015

Louapre, C; Govindarajan, ST; Giannì, C; Langkammer, C; Sloane, JA; Kinkel, RP; Mainero, C Beyond focal cortical lesions in MS: An in vivo quantitative and spatial imaging study at 7T.
Neurology. 2015; 85(19): 1702-1709. Doi: 10.1212/WNL.0000000000002106 [OPEN ACCESS]
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Rittchen, S; Boyd, A; Burns, A; Park, J; Fahmy, TM; Metcalfe, S; Williams, A Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF).
Biomaterials. 2015; 56: 78-85. Doi: 10.1016/j.biomaterials.2015.03.044 [OPEN ACCESS]
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2014

Bosticardo, M; Musio, S; Fontana, E; Angiari, S; Draghici, E; Constantin, G; Poliani, PL; Pedotti, R; Villa, A Development of central nervous system autoimmunity is impaired in the absence of Wiskott-Aldrich syndrome protein.
PLoS One. 2014; 9(1): e86942-e86942. Doi: 10.1371/journal.pone.0086942 [OPEN ACCESS]
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Seiler, S; Ropele, S; Schmidt, R Magnetization transfer imaging for in vivo detection of microstructural tissue changes in aging and dementia: a short literature review.
J Alzheimers Dis. 2014; 42 Suppl 3(5):S229-S237 Doi: 10.3233/JAD-132750
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2013

Adzemovic, MZ; Zeitelhofer, M; Hochmeister, S; Gustafsson, SA; Jagodic, M Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage.
Exp Neurol. 2013; 249(12):39-48 Doi: 10.1016/j.expneurol.2013.08.002 [OPEN ACCESS]
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Fazekas, F; Bajenaru, O; Berger, T; Fabjan, TH; Ledinek, AH; Jakab, G; Komoly, S; Kobys, T; Kraus, J; Kurča, E; Kyriakides, T; Lisý, L; Milanov, I; Nehrych, T; Moskovko, S; Panayiotou, P; Jazbec, SŠ; Sokolova, L; Taláb, R; Traykov, L; Turčáni, P; Vass, K; Vella, N; Voloshyná, N; Havrdová, E How does fingolimod (gilenya(®)) fit in the treatment algorithm for highly active relapsing-remitting multiple sclerosis?
Front Neurol. 2013; 4(2):10-10 Doi: 10.3389/fneur.2013.00010 [OPEN ACCESS]
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Koelblinger, C; Fruehwald-Pallamar, J; Kubin, K; Wallner-Blazek, M; van den Hauwe, L; Macedo, L; Puchner, SB; Thurnher, MM Atypical idiopathic inflammatory demyelinating lesions (IIDL): conventional and diffusion-weighted MR imaging (DWI) findings in 42 cases.
Eur J Radiol. 2013; 82(11):1996-2004 Doi: 10.1016/j.ejrad.2013.07.026
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2012

Adzemovic, MZ; Ockinger, J; Zeitelhofer, M; Hochmeister, S; Beyeen, AD; Paulson, A; Gillett, A; Hedreul, MT; Covacu, R; Lassmann, H; Olsson, T; Jagodic, M Expression of Ccl11 Associates with Immune Response Modulation and Protection against Neuroinflammation in Rats.
PLoS One. 2012; 7(7):e39794-e39794 Doi: 10.1371/journal.pone.0039794 [OPEN ACCESS]
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Fairless, R; Williams, SK; Hoffmann, DB; Stojic, A; Hochmeister, S; Schmitz, F; Storch, MK; Diem, R Preclinical retinal neurodegeneration in a model of multiple sclerosis.
J Neurosci. 2012; 32(16): 5585-5597. Doi: 10.1523/JNEUROSCI.5705-11.2012 [OPEN ACCESS]
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2011

Valsasina, P; Rocca, MA; Absinta, M; Sormani, MP; Mancini, L; De Stefano, N; Rovira, A; Gass, A; Enzinger, C; Barkhof, F; Wegner, C; Matthews, PM; Filippi, M A multicentre study of motor functional connectivity changes in patients with multiple sclerosis.
Eur J Neurosci. 2011; 33(7): 1256-1263. Doi: 10.1111/j.1460-9568.2011.07623.x
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2010

Grauer, O; Wolff, D; Bertz, H; Greinix, H; Kühl, JS; Lawitschka, A; Lee, SJ; Pavletic, SZ; Holler, E; Kleiter, I Neurological manifestations of chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: report from the Consensus Conference on Clinical Practice in chronic graft-versus-host disease.
Brain. 2010; 133(10): 2852-2865. Doi: 10.1093/brain/awq245 [OPEN ACCESS]
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Mader, S; Lutterotti, A; Di Pauli, F; Kuenz, B; Schanda, K; Aboul-Enein, F; Khalil, M; Storch, MK; Jarius, S; Kristoferitsch, W; Berger, T; Reindl, M Patterns of Antibody Binding to Aquaporin-4 Isoforms in Neuromyelitis Optica
PLOS ONE. 2010; 5(5): e10455-e10455. Doi: 10.1371/journal.pone.0010455 [OPEN ACCESS]
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Nusshold, C; Kollroser, M; Köfeler, H; Rechberger, G; Reicher, H; Ullen, A; Bernhart, E; Waltl, S; Kratzer, I; Hermetter, A; Hackl, H; Trajanoski, Z; Hrzenjak, A; Malle, E; Sattler, W Hypochlorite modification of sphingomyelin generates chlorinated lipid species that induce apoptosis and proteome alterations in dopaminergic PC12 neurons in vitro.
Free Radic Biol Med. 2010; 48(12): 1588-1600. Doi: 10.1016/j.freeradbiomed.2010.02.037 [OPEN ACCESS]
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van den Elskamp, IJ; Knol, DL; Vrenken, H; Karas, G; Meijerman, A; Filippi, M; Kappos, L; Fazekas, F; Wagner, K; Pohl, C; Sandbrink, R; Polman, CH; Uitdehaag, BMJ; Barkhof, F Lesional magnetization transfer ratio: a feasible outcome for remyelinating treatment trials in multiple sclerosis.
Mult Scler. 2010; 16(6):660-669 Doi: 10.1177/1352458510364630
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2009

Constantin, G; Marconi, S; Rossi, B; Angiari, S; Calderan, L; Anghileri, E; Gini, B; Bach, SD; Martinello, M; Bifari, F; Galiè, M; Turano, E; Budui, S; Sbarbati, A; Krampera, M; Bonetti, B Adipose-derived mesenchymal stem cells ameliorate chronic experimental autoimmune encephalomyelitis.
Stem Cells. 2009; 27(10): 2624-2635. Doi: 10.1002/stem.194 [OPEN ACCESS]
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Foster, CA; Mechtcheriakova, D; Storch, MK; Balatoni, B; Howard, LM; Bornancin, F; Wlachos, A; Sobanov, J; Kinnunen, A; Baumruker, T FTY720 rescue therapy in the dark agouti rat model of experimental autoimmune encephalomyelitis: expression of central nervous system genes and reversal of blood-brain-barrier damage.
Brain Pathol. 2009; 19(2):254-266 Doi: 10.1111/j.1750-3639.2008.00182.x
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2008

Auer-Grumbach, M; Fischer, C; Papić, L; John, E; Plecko, B; Bittner, RE; Bernert, G; Pieber, TR; Miltenberger, G; Schwarz, R; Windpassinger, C; Grill, F; Timmerman, V; Speicher, MR; Janecke, AR Two novel mutations in the GDAP1 and PRX genes in early onset Charcot-Marie-Tooth syndrome.
Neuropediatrics. 2008; 39(1):33-38 Doi: 10.1055/s-2008-1077085 [OPEN ACCESS]
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de Graaf, KL; Barth, S; Herrmann, MM; Storch, MK; Wiesmüller, KH; Weissert, R Characterization of the encephalitogenic immune response in a model of multiple sclerosis.
Eur J Immunol. 2008; 38(1):299-308 Doi: 10.1002/eji.200737475 [OPEN ACCESS]
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2007

Balatoni, B; Storch, MK; Swoboda, EM; Schönborn, V; Koziel, A; Lambrou, GN; Hiestand, PC; Weissert, R; Foster, CA FTY720 sustains and restores neuronal function in the DA rat model of MOG-induced experimental autoimmune encephalomyelitis.
Brain Res Bull. 2007; 74(5):307-316 Doi: 10.1016/j.brainresbull.2007.06.023
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Seifert, T; Bauer, J; Weissert, R; Fazekas, F; Storch, MK Notch1 and its ligand Jagged1 are present in remyelination in a T-cell- and antibody-mediated model of inflammatory demyelination.
Acta Neuropathol (Berl). 2007; 113(2): 195-203. Doi: 10.1007/s00401-006-0170-9
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2006

Storch, MK; Bauer, J; Linington, C; Olsson, T; Weissert, R; Lassmann, H Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatability complex (MHC) haplotype-related.
J Neuropathol Exp Neurol. 2006; 65(12):1137-1142 Doi: 10.1097/01.jnen.0000248547.13176.9d [OPEN ACCESS]
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2005

Enzinger, C; Strasser-Fuchs, S; Ropele, S; Kapeller, P; Kleinert, R; Fazekas, F Tumefactive demyelinating lesions: conventional and advanced magnetic resonance imaging.
MULT SCLER. 2005; 11: 135-139. Doi: 10.1191/1352http://dx.doi.org/10.1191/1352458505ms1145oa (- Case Report)
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Filippi, M; Falini, A; Arnold, DL; Fazekas, F; Gonen, O; Simon, JH; Dousset, V; Savoiardo, M; Wolinsky, JS; White Matter Study Group Magnetic resonance techniques for the in vivo assessment of multiple sclerosis pathology: consensus report of the white matter study group.
J Magn Reson Imaging. 2005; 21(6):669-675 Doi: 10.1002/jmri.20336
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2004

Maier, K; Rau, CR; Storch, MK; Sättler, MB; Demmer, I; Weissert, R; Taheri, N; Kuhnert, AV; Bähr, M; Diem, R Ciliary neurotrophic factor protects retinal ganglion cells from secondary cell death during acute autoimmune optic neuritis in rats.
Brain Pathol. 2004; 14(4):378-387 Doi: 10.1111/j.1750-3639.2004.tb00081.x
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2003

Neuhaus, O; Archelos, JJ; Hartung, HP Immunomodulation in multiple sclerosis: from immunosuppression to neuroprotection.
Trends Pharmacol Sci. 2003; 24(3):131-138 Doi: 10.1016%2FS0165-6147%2803%2900028-2
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Plecko, B; Stöckler-Ipsiroglu, S; Gruber, S; Mlynarik, V; Moser, E; Simbrunner, J; Ebner, F; Bernert, G; Harrer, G; Gal, A; Prayer, D Degree of hypomyelination and magnetic resonance spectroscopy findings in patients with Pelizaeus Merzbacher phenotype.
Neuropediatrics. 2003; 34(3):127-136 Doi: 10.1055/s-2003-41276
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Suneetha, LM; Singh, SS; Vani, M; Vardhini, D; Scollard, D; Archelos, JJ; Srinivasulu, M; Suneetha, S Mycobacterium leprae binds to a major human peripheral nerve glycoprotein myelin P zero (P0).
Neurochem Res. 2003; 28(9):1393-1399 Doi: 10.1023%2FA%3A1024904717612
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Weissert, R; Wiendl, H; Pfrommer, H; Storch, MK; Schreiner, B; Barth, S; Seifert, T; Melms, A; Dichgans, J; Weller, M Action of treosulfan in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis and human lymphocytes.
J NEUROIMMUNOL 2003 144: 28-37. Doi: 10.1016%2Fj.jneuroim.2003.08.028
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2002

Storch, MK; Weissert, R; Steffer, A; Birnbacher, R; Wallström, E; Dahlman, I; Ostensson, CG; Linington, C; Olsson, T; Lassmann, H MHC gene related effects on microglia and macrophages in experimental autoimmune encephalomyelitis determine the extent of axonal injury.
Brain Pathol. 2002; 12(3):287-299 Doi: 10.1111/j.1750-3639.2002.tb00443.x
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2001

Andorfer, B; Kieseier, BC; Mathey, E; Armati, P; Pollard, J; Oka, N; Hartung, HP Expression and distribution of transcription factor NF-kappaB and inhibitor IkappaB in the inflamed peripheral nervous system.
J Neuroimmunol. 2001; 116(2):226-232 Doi: 10.1016%2FS0165-5728%2801%2900306-X
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Kiefer, R; Kieseier, BC; Stoll, G; Hartung, HP The role of macrophages in immune-mediated damage to the peripheral nervous system
PROG NEUROBIOL. 2001; 64(2): 109-127. Doi: 10.1016/S0301-0082(00)00060-5
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Kornek, B; Storch, MK; Bauer, J; Djamshidian, A; Weissert, R; Wallstroem, E; Stefferl, A; Zimprich, F; Olsson, T; Linington, C; Schmidbauer, M; Lassmann, H Distribution of a calcium channel subunit in dystrophic axons in multiple sclerosis and experimental autoimmune encephalomyelitis.
Brain. 2001; 124(Pt 6):1114-1124 Doi: 10.1093/brain/124.6.1114 [OPEN ACCESS]
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