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Publikationen

Suchbegriffe: DNA-BINDING PROTEINS - GENETICS , . Treffer: 65

2022

Nakauchi, Y; Azizi, A; Thomas, D; Corces, MR; Reinisch, A; Sharma, R; Cruz, Hernandez, D; Köhnke, T; Karigane, D; Fan, A; Martinez-Krams, D; Stafford, M; Kaur, S; Dutta, R; Phan, P; Ediriwickrema, A; McCarthy, E; Ning, Y; Phillips, T; Ellison, CK; Guler, GD; Bergamaschi, A; Ku, CJ; Levy, S; Majeti, R The Cell Type-Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia.
Blood Cancer Discov. 2022; 3(4):346-367 Doi: 10.1158/2643-3230.BCD-21-0143 [OPEN ACCESS]
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2021

Robier, C; Hoefler, G; Aubell, K; Hubmann, E Acquired elliptocytosis as presenting sign of a myelodysplastic syndrome associated with deletion of chromosome 20 and mutations in TET2, DNMT3A, and U2AF1.
Ann Hematol. 2021; 100(8):2111-2112 Doi: 10.1007/s00277-020-04368-w (- Case Report)
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2020

Ali, MZ; Blatterer, J; Khan, MA; Schaflinger, E; Petek, E; Ahmad, S; Khan, E; Windpassinger, C Identification of a novel protein truncating mutation p.Asp98* in XPC associated with xeroderma pigmentosum in a consanguineous Pakistani family.
Mol Genet Genomic Med. 2020; 8(2):e1060 Doi: 10.1002/mgg3.1060 (- Case Report) [OPEN ACCESS]
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2017

Deutsch, AJA; Rinner, B; Pichler, M; Prochazka, K; Pansy, K; Bischof, M; Fechter, K; Hatzl, S; Feichtinger, J; Wenzl, K; Frisch, MT; Stiegelbauer, V; Prokesch, A; Krogsdam, A; Sill, H; Thallinger, GG; Greinix, HT; Wang, C; Beham-Schmid, C; Neumeister, P NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.
Cancer Res. 2017; 77(9):2375-2386 Doi: 10.1158/0008-5472.CAN-16-2320 [OPEN ACCESS]
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2016

Gomez-Escobar, N; Almobadel, N; Alzahrani, O; Feichtinger, J; Planells-Palop, V; Alshehri, Z; Thallinger, GG; Wakeman, JA; McFarlane, RJ Translin and Trax differentially regulate telomere-associated transcript homeostasis.
Oncotarget. 2016; 7(23): 33809-33820. Doi: 10.18632/oncotarget.9278 [OPEN ACCESS]
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Hartmann, L; Dutta, S; Opatz, S; Vosberg, S; Reiter, K; Leubolt, G; Metzeler, KH; Herold, T; Bamopoulos, SA; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Hopfner, KP; Graf, A; Krebs, S; Blum, H; Middeke, JM; Stölzel, F; Thiede, C; Wolf, S; Bohlander, SK; Preiss, C; Chen-Wichmann, L; Wichmann, C; Sauerland, MC; Büchner, T; Berdel, WE; Wörmann, BJ; Braess, J; Hiddemann, W; Spiekermann, K; Greif, PA ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
Nat Commun. 2016; 7(1): 11733-11733. Doi: 10.1038/ncomms11733 [OPEN ACCESS]
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2015

Fisser, MC; Rommer, A; Steinleitner, K; Heller, G; Herbst, F; Wiese, M; Glimm, H; Sill, H; Wieser, R Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.
Mol Carcinog. 2015; 54(12):1815-1819 Doi: 10.1002/mc.22252 [OPEN ACCESS]
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Rockstroh, D; Landgraf, K; Wagner, IV; Gesing, J; Tauscher, R; Lakowa, N; Kiess, W; Bühligen, U; Wojan, M; Till, H; Blüher, M; Körner, A Direct evidence of brown adipocytes in different fat depots in children.
PLoS One. 2015; 10(2):e0117841-e0117841 Doi: 10.1371/journal.pone.0117841 [OPEN ACCESS]
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Wenzl, K; Troppan, K; Neumeister, P; Deutsch, AJ The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.
Curr Drug Targets. 2015; 16(1):38-46 Doi: 10.2174/1389450115666141120112818
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2014

Deutsch, AJ; Rinner, B; Wenzl, K; Pichler, M; Troppan, K; Steinbauer, E; Schwarzenbacher, D; Reitter, S; Feichtinger, J; Tierling, S; Prokesch, A; Scheideler, M; Krogsdam, A; Thallinger, GG; Schaider, H; Beham-Schmid, C; Neumeister, P NR4A1-mediated apoptosis suppresses lymphomagenesis and is associated with a favorable cancer-specific survival in patients with aggressive B-cell lymphomas.
Blood. 2014; 123(15):2367-2377 Doi: 10.1182/blood-2013-08-518878 [OPEN ACCESS]
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Goessweiner-Mohr, N; Fercher, C; Arends, K; Birner-Gruenberger, R; Laverde-Gomez, D; Huebner, J; Grohmann, E; Keller, W The type IV secretion protein TraK from the Enterococcus conjugative plasmid pIP501 exhibits a novel fold.
Acta Crystallogr D Biol Crystallogr. 2014; 70(Pt 4):1124-1135 Doi: 10.1107/S1399004714001606 [OPEN ACCESS]
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2013

Dorronsoro, A; Lang, V; Jakobsson, E; Ferrin, I; Salcedo, JM; Fernández-Rueda, J; Fechter, K; Rodriguez, MS; Trigueros, C Identification of the NF-κB inhibitor A20 as a key regulator for human adipogenesis.
Cell Death Dis. 2013; 4(1):e972-e972 Doi: 10.1038/cddis.2013.494 [OPEN ACCESS]
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Mairinger, F; Vollbrecht, C; Mairinger, T; Popper, H The issue of studies evaluating biomarkers which predict outcome after pemetrexed-based chemotherapy in malignant pleural mesothelioma.
J Thorac Oncol. 2013; 8(8):e80-e82 Doi: 10.1097/JTO.0b013e31829b1cf9 [OPEN ACCESS]
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Stulnig, G; Frisch, MT; Crnkovic, S; Stiegler, P; Sereinigg, M; Stacher, E; Olschewski, H; Olschewski, A; Frank, S Docosahexaenoic acid (DHA)-induced heme oxygenase-1 attenuates cytotoxic effects of DHA in vascular smooth muscle cells.
Atherosclerosis. 2013; 230(2):406-413 Doi: 10.1016/j.atherosclerosis.2013.08.002
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Szkandera, J; Absenger, G; Liegl-Atzwanger, B; Pichler, M; Stotz, M; Gerger, S; Zacherl, M; Renner, W; Haijun, M; Leithner, A; Gerger, A Common gene variants in RAD51, XRCC2 and XPD are not associated with clinical outcome in soft-tissue sarcoma patients.
Cancer Epidemiol. 2013; 37(6):1003-1009 Doi: 10.1016/j.canep.2013.10.003
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Zebisch, A; Hoefler, G; Quehenberger, F; Wölfler, A; Sill, H Mutant DNMT3A in acute myeloid leukemia: guilty of inducing genetic instability?
Leukemia. 2013; 27(8): 1777-1778. Doi: 10.1038/leu.2013.48 [OPEN ACCESS]
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2011

Demuth, I; Dutrannoy, V; Marques, W; Neitzel, H; Schindler, D; Dimova, PS; Chrzanowska, KH; Bojinova, V; Gregorek, H; Graul-Neumann, LM; von Moers, A; Schulze, I; Nicke, M; Bora, E; Cankaya, T; Oláh, É; Kiss, C; Bessenyei, B; Szakszon, K; Gruber-Sedlmayr, U; Kroisel, PM; Sodia, S; Goecke, TO; Dörk, T; Digweed, M; Sperling, K; de Sá, J; Lourenco, CM; Varon, R New mutations in the ATM gene and clinical data of 25 AT patients.
Neurogenetics. 2011; 12(4):273-282 Doi: 10.1007/s10048-011-0299-0
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Kohlmann, A; Klein, HU; Weissmann, S; Bresolin, S; Chaplin, T; Cuppens, H; Haschke-Becher, E; Garicochea, B; Grossmann, V; Hanczaruk, B; Hebestreit, K; Gabriel, C; Iacobucci, I; Jansen, JH; te Kronnie, G; van de Locht, L; Martinelli, G; McGowan, K; Schweiger, MR; Timmermann, B; Vandenberghe, P; Young, BD; Dugas, M; Haferlach, T The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories.
Leukemia. 2011; 25(12): 1840-1848. Doi: 10.1038/leu.2011.155 [OPEN ACCESS]
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Langsenlehner, T; Renner, W; Gerger, A; Hofmann, G; Thurner, EM; Kapp, KS; Langsenlehner, U Association between single nucleotide polymorphisms in the gene for XRCC1 and radiation-induced late toxicity in prostate cancer patients.
Radiother Oncol. 2011; 98(3):387-393 Doi: 10.1016/j.radonc.2011.01.021
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Schrama, D; Scherer, D; Schneider, M; Zapatka, M; Bröcker, EB; Schadendorf, D; Ugurel, S; Kumar, R; Becker, JC ERCC5 p.Asp1104His and ERCC2 p.Lys751Gln Polymorphisms Are Independent Prognostic Factors for the Clinical Course of Melanoma.
J Invest Dermatol. 2011; 131(6):1280-1290 Doi: 10.1038/jid.2011.35 [OPEN ACCESS]
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Tatton-Brown, K; Hanks, S; Ruark, E; Zachariou, A; Duarte, Sdel V; Ramsay, E; Snape, K; Murray, A; Perdeaux, ER; Seal, S; Loveday, C; Banka, S; Clericuzio, C; Flinter, F; Magee, A; McConnell, V; Patton, M; Raith, W; Rankin, J; Splitt, M; Strenger, V; Taylor, C; Wheeler, P; Temple, KI; Cole, T; Childhood Overgrowth Collaboration; Douglas, J; Rahman, N Germline mutations in the oncogene EZH2 cause Weaver syndrome and increased human height.
Oncotarget. 2011; 2(12):1127-1133 Doi: 10.18632/oncotarget.385 [OPEN ACCESS]
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2010

Georgiadis, A; Tschernutter, M; Bainbridge, JW; Balaggan, KS; Mowat, F; West, EL; Munro, PM; Thrasher, AJ; Matter, K; Balda, MS; Ali, RR The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice.
PLoS One. 2010; 5(12): e15730-e15730. Doi: 10.1371/journal.pone.0015730 [OPEN ACCESS]
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Houlden, H; Schneider, SA; Paudel, R; Melchers, A; Schwingenschuh, P; Edwards, M; Hardy, J; Bhatia, KP THAP1 mutations (DYT6) are an additional cause of early-onset dystonia.
Neurology. 2010; 74(10): 846-850. Doi: 10.1212/WNL.0b013e3181d5276d [OPEN ACCESS]
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Landgraeber, S; von Knoch, M; Loer, F; Wegner, A; Tsokos, M; Schmid, KW; Totsch, M ERCC1 expression in aseptic loosening after total hip replacement
J BIOMED MATER RES PART A. 2010; 92A(2): 556-562. Doi: 10.1002/jbm.a.32391
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Meyer, NH; Tripsianes, K; Vincendeau, M; Madl, T; Kateb, F; Brack-Werner, R; Sattler, M Structural basis for homodimerization of the Src-associated during mitosis, 68-kDa protein (Sam68) Qua1 domain.
J Biol Chem. 2010; 285(37): 28893-28901. Doi: 10.1074/jbc.M110.126185 [OPEN ACCESS]
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2009

Kratzer, A; Buchebner, M; Pfeifer, T; Becker, TM; Uray, G; Miyazaki, M; Miyazaki-Anzai, S; Ebner, B; Chandak, PG; Kadam, RS; Calayir, E; Rathke, N; Ahammer, H; Radovic, B; Trauner, M; Hoefler, G; Kompella, UB; Fauler, G; Levi, M; Levak-Frank, S; Kostner, GM; Kratky, D Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.
J Lipid Res. 2009; 50(2): 312-326. Doi: 10.1194/jlr.M800376-JLR200 [OPEN ACCESS]
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Mihajlovic, S; Lang, S; Sut, MV; Strohmaier, H; Gruber, CJ; Koraimann, G; Cabezón, E; Moncalián, G; de la Cruz, F; Zechner, EL Plasmid r1 conjugative DNA processing is regulated at the coupling protein interface.
J Bacteriol. 2009; 191(22): 6877-6887. Doi: 10.1128/JB.00918-09 [OPEN ACCESS]
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Wygrecka, M; Marsh, LM; Morty, RE; Henneke, I; Guenther, A; Lohmeyer, J; Markart, P; Preissner, KT Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung.
Blood. 2009; 113(22): 5588-5598. Doi: 10.1182/blood-2008-08-170837 [OPEN ACCESS]
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2008

Hochrainer, K; Kroismayr, R; Baranyi, U; Binder, BR; Lipp, J Highly homologous HERC proteins localize to endosomes and exhibit specific interactions with hPLIC and Nm23B.
Cell Mol Life Sci. 2008; 65(13):2105-2117 Doi: 10.1007/s00018-008-8148-5
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Ralmer, N; Hoefler, G; Hogenauer, C; Lackner, C; Steinke, V; Sengteller, M; Friedl, W; Aretz, S; Propping, P; Mangold, E; Walldorf, C Compound heterozygosity for two MSH6 mutations in a patient with early onset colorectal cancer, vitiligo and systemic lupus erythematosus.
AM J MED GENET PART A. 2008; 146A(10): 1314-1319. Doi: 10.1002/ajmg.a.32210 (- Case Report)
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2007

Ali, A; Christie, PT; Grigorieva, IV; Harding, B; Van Esch, H; Ahmed, SF; Bitner-Glindzicz, M; Blind, E; Bloch, C; Christin, P; Clayton, P; Gecz, J; Gilbert-Dussardier, B; Guillen-Navarro, E; Hackett, A; Halac, I; Hendy, GN; Lalloo, F; Mache, CJ; Mughal, Z; Ong, AC; Rinat, C; Shaw, N; Smithson, SF; Tolmie, J; Weill, J; Nesbit, MA; Thakker, RV Functional characterization of GATA3 mutations causing the hypoparathyroidism-deafness-renal (HDR) dysplasia syndrome: insight into mechanisms of DNA binding by the GATA3 transcription factor.
HUM MOL GENET. 2007; 16(3): 265-275. Doi: 10.1093/hmg/ddl454 [OPEN ACCESS]
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2006

Marschall, HU; Wagner, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjövall, J; Trauner, M Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.
J Lipid Res. 2006; 47(3):582-592 Doi: 10.1194/jlr.M500427-JLR200 [OPEN ACCESS]
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Olaussen, KA; Dunant, A; Fouret, P; Brambilla, E; André, F; Haddad, V; Taranchon, E; Filipits, M; Pirker, R; Popper, HH; Stahel, R; Sabatier, L; Pignon, JP; Tursz, T; Le Chevalier, T; Soria, JC; IALT Bio Investigators DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy.
N ENGL J MED. 2006; 355: 983-991. Doi: 10.1056/NEJMoa060570 [OPEN ACCESS]
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Strehl, S; König, M; Meyer, C; Schneider, B; Harbott, J; Jäger, U; von Bergh, AR; Loncarevic, IF; Jarosova, M; Schmidt, HH; Moore, SD; Marschalek, R; Haas, OA Molecular dissection of t(11;17) in acute myeloid leukemia reveals a variety of gene fusions with heterogeneous fusion transcripts and multiple splice variants.
Genes Chromosomes Cancer. 2006; 45(11):1041-1049 Doi: 10.1002/gcc.20372
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Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Halilbasic, E; Denk, H; Marschall, HU; Trauner, M Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(5):G923-G932 Doi: 10.1152/ajpgi.00490.2005 [OPEN ACCESS]
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2005

Claudel, T; Staels, B; Kuipers, F The Farnesoid X receptor: a molecular link between bile acid and lipid and glucose metabolism.
Arterioscler Thromb Vasc Biol. 2005; 25(10): 2020-2030. Doi: 10.1161/01.ATV.0000178994.21828.a7 [OPEN ACCESS]
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Einspieler, C; Kerr, AM; Prechtl, HF Is the early development of girls with Rett disorder really normal?
PEDIAT RES. 2005; 57(5 Pt 1): 696-700. Doi: 10.1203/01.PDR.0000155945.94249.0A [OPEN ACCESS]
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Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M Cytokine-independent repression of rodent Ntcp in obstructive cholestasis.
Hepatology. 2005; 41(3):470-477 Doi: 10.1002/hep.20594 [OPEN ACCESS]
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Item, CB; Turhani, D; Thurnher, D; Yerit, K; Sinko, K; Wittwer, G; Adeyemo, WL; Frei, K; Erginel-Unaltuna, N; Watzinger, F; Ewers, R Van Der Woude syndrome: variable penetrance of a novel mutation (p.Arg 84Gly) of the IRF6 gene in a Turkish family.
Int J Mol Med. 2005; 15(2):247-251 Doi: 10.3892/ijmm.15.2.247 (- Case Report)
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Nebral, K; Schmidt, HH; Haas, OA; Strehl, S NUP98 is fused to topoisomerase (DNA) IIbeta 180 kDa (TOP2B) in a patient with acute myeloid leukemia with a new t(3;11)(p24;p15).
Clin Cancer Res. 2005; 11(18):6489-6494 Doi: 10.1158/1078-0432.CCR-05-0150 (- Case Report) [OPEN ACCESS]
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2004

Hendriks, YM; Wagner, A; Morreau, H; Menko, F; Stormorken, A; Quehenberger, F; Sandkuijl, L; Møller, P; Genuardi, M; Van Houwelingen, H; Tops, C; Van Puijenbroek, M; Verkuijlen, P; Kenter, G; Van Mil, A; Meijers-Heijboer, H; Tan, GB; Breuning, MH; Fodde, R; Wijnen, JT; Bröcker-Vriends, AH; Vasen, H Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.
Gastroenterology. 2004; 127(1):17-25 Doi: 10.1053/j.gastro.2004.03.068
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Item, CB; Turhani, D; Thurnher, D; Sinko, K; Yerit, K; Galev, K; Wittwer, G; Lanre Adeyemo, W; Klemens, F; Ewers, R; Watzinger, F Gene symbol: IRF6. Disease: Van der Woude syndrome.
Hum Genet. 2004; 115(2):175-175
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Oberkofler, H; Schraml, E; Krempler, F; Patsch, W Restoration of sterol-regulatory-element-binding protein-1c gene expression in HepG2 cells by peroxisome-proliferator-activated receptor-gamma co-activator-1alpha.
Biochem J. 2004; 381(Pt 2): 357-363. Doi: 10.1042/BJ20040173 [OPEN ACCESS]
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Prüfert, K; Winkler, C; Paulin-Levasseur, M; Krohne, G The lamina-associated polypeptide 2 (LAP2) genes of zebrafish and chicken: no LAP2alpha isoform is synthesised by non-mammalian vertebrates.
Eur J Cell Biol. 2004; 83(8): 403-411. Doi: 10.1078/0171-9335-00402
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Schrem, H; Klempnauer, J; Borlak, J Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation.
Pharmacol Rev. 2004; 56(2): 291-330. Doi: 10.1124/pr.56.2.5
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Wagner, EM; Kratky, D; Haemmerle, G; Hrzenjak, A; Kostner, GM; Steyrer, E; Zechner, R Defective uptake of triglyceride-associated fatty acids in adipose tissue causes the SREBP-1c-mediated induction of lipogenesis.
J LIPID RES. 2004; 45(2): 356-365. Doi: 10.1194/jlr.M300293-JLR200 [OPEN ACCESS]
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Zatkova, A; Ullmann, R; Rouillard, JM; Lamb, BJ; Kuick, R; Hanash, SM; Schnittger, S; Schoch, C; Fonatsch, C; Wimmer, K Distinct sequences on 11q13.5 and 11q23-24 are frequently coamplified with MLL in complexly organized 11q amplicons in AML/MDS patients.
Genes Chromosomes Cancer. 2004; 39(4):263-276 Doi: 10.1002/gcc.20002
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2003

Karaghiosoff, M; Steinborn, R; Kovarik, P; Kriegshäuser, G; Baccarini, M; Donabauer, B; Reichart, U; Kolbe, T; Bogdan, C; Leanderson, T; Levy, D; Decker, T; Müller, M Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.
Nat Immunol. 2003; 4(5):471-477 Doi: 10.1038/ni910
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Pfeifhofer, C; Kofler, K; Gruber, T; Tabrizi, NG; Lutz, C; Maly, K; Leitges, M; Baier, G Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells.
J Exp Med. 2003; 197(11):1525-1535 Doi: 10.1084/jem.20020234 [OPEN ACCESS]
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Plecko, B; Stöckler-Ipsiroglu, S; Gruber, S; Mlynarik, V; Moser, E; Simbrunner, J; Ebner, F; Bernert, G; Harrer, G; Gal, A; Prayer, D Degree of hypomyelination and magnetic resonance spectroscopy findings in patients with Pelizaeus Merzbacher phenotype.
Neuropediatrics. 2003; 34(3):127-136 Doi: 10.1055/s-2003-41276
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