Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: COMPUTATIONAL BIOLOGY - , . Treffer: 40

2019

Holzinger, A; Haibe-Kains, B; Jurisica, I Why imaging data alone is not enough: AI-based integration of imaging, omics, and clinical data.
Eur J Nucl Med Mol Imaging. 2019; 46(13):2722-2730 Doi: 10.1007/s00259-019-04382-9
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2018

Kodra, Y; Weinbach, J; Posada-de-la-Paz, M; Coi, A; Lemonnier, SL; van Enckevort, D; Roos, M; Jacobsen, A; Cornet, R; Ahmed, SF; Bros-Facer, V; Popa, V; Van Meel, M; Renault, D; von Gizycki, R; Santoro, M; Landais, P; Torreri, P; Carta, C; Mascalzoni, D; Gainotti, S; Lopez, E; Ambrosini, A; Müller, H; Reis, R; Bianchi, F; Rubinstein, YR; Lochmüller, H; Taruscio, D Recommendations for Improving the Quality of Rare Disease Registries.
Int J Environ Res Public Health. 2018; 15(8): Doi: 10.3390/ijerph15081644 [OPEN ACCESS]
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2017

Costea, PI; Zeller, G; Sunagawa, S; Pelletier, E; Alberti, A; Levenez, F; Tramontano, M; Driessen, M; Hercog, R; Jung, FE; Kultima, JR; Hayward, MR; Coelho, LP; Allen-Vercoe, E; Bertrand, L; Blaut, M; Brown, JRM; Carton, T; Cools-Portier, S; Daigneault, M; Derrien, M; Druesne, A; de Vos, WM; Finlay, BB; Flint, HJ; Guarner, F; Hattori, M; Heilig, H; Luna, RA; van Hylckama Vlieg, J; Junick, J; Klymiuk, I; Langella, P; Le Chatelier, E; Mai, V; Manichanh, C; Martin, JC; Mery, C; Morita, H; O'Toole, PW; Orvain, C; Patil, KR; Penders, J; Persson, S; Pons, N; Popova, M; Salonen, A; Saulnier, D; Scott, KP; Singh, B; Slezak, K; Veiga, P; Versalovic, J; Zhao, L; Zoetendal, EG; Ehrlich, SD; Dore, J; Bork, P Towards standards for human fecal sample processing in metagenomic studies.
Nat Biotechnol. 2017; 35(11):1069-1076 Doi: 10.1038/nbt.3960 [OPEN ACCESS]
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Crespo, N; Sánchez-Murcia, PA; Gago, F; Cejudo-Sanches, J; Galmes, MA; Fernández-Lucas, J; Mancheño, JM 2'-Deoxyribosyltransferase from Leishmania mexicana, an efficient biocatalyst for one-pot, one-step synthesis of nucleosides from poorly soluble purine bases.
Appl Microbiol Biotechnol. 2017; 101(19):7187-7200 Doi: 10.1007/s00253-017-8450-y
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Zadora, J; Singh, M; Herse, F; Przybyl, L; Haase, N; Golic, M; Yung, HW; Huppertz, B; Cartwright, JE; Whitley, G; Johnsen, GM; Levi, G; Isbruch, A; Schulz, H; Luft, FC; Müller, DN; Staff, AC; Hurst, LD; Dechend, R; Izsvák, Z Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker.
CIRCULATION. 2017; 136(19): 1824-1839. Doi: 10.1161/CIRCULATIONAHA.117.028110 [OPEN ACCESS]
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2016

Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 Doi: 10.18632/oncotarget.9418 [OPEN ACCESS]
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Moreno-Viedma, V; Amor, M; Sarabi, A; Bilban, M; Staffler, G; Zeyda, M; Stulnig, TM Common dysregulated pathways in obese adipose tissue and atherosclerosis.
Cardiovasc Diabetol. 2016; 15(1): 120-120. Doi: 10.1186/s12933-016-0441-2 [OPEN ACCESS]
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Okbay, A; Beauchamp, JP; Fontana, MA; Lee, JJ; Pers, TH; Rietveld, CA; Turley, P; Chen, GB; Emilsson, V; Meddens, SF; Oskarsson, S; Pickrell, JK; Thom, K; Timshel, P; de Vlaming, R; Abdellaoui, A; Ahluwalia, TS; Bacelis, J; Baumbach, C; Bjornsdottir, G; Brandsma, JH; Pina Concas, M; Derringer, J; Furlotte, NA; Galesloot, TE; Girotto, G; Gupta, R; Hall, LM; Harris, SE; Hofer, E; Horikoshi, M; Huffman, JE; Kaasik, K; Kalafati, IP; Karlsson, R; Kong, A; Lahti, J; van der Lee, SJ; deLeeuw, C; Lind, PA; Lindgren, KO; Liu, T; Mangino, M; Marten, J; Mihailov, E; Miller, MB; van der Most, PJ; Oldmeadow, C; Payton, A; Pervjakova, N; Peyrot, WJ; Qian, Y; Raitakari, O; Rueedi, R; Salvi, E; Schmidt, B; Schraut, KE; Shi, J; Smith, AV; Poot, RA; St Pourcain, B; Teumer, A; Thorleifsson, G; Verweij, N; Vuckovic, D; Wellmann, J; Westra, HJ; Yang, J; Zhao, W; Zhu, Z; Alizadeh, BZ; Amin, N; Bakshi, A; Baumeister, SE; Biino, G; Bønnelykke, K; Boyle, PA; Campbell, H; Cappuccio, FP; Davies, G; De Neve, JE; Deloukas, P; Demuth, I; Ding, J; Eibich, P; Eisele, L; Eklund, N; Evans, DM; Faul, JD; Feitosa, MF; Forstner, AJ; Gandin, I; Gunnarsson, B; Halldórsson, BV; Harris, TB; Heath, AC; Hocking, LJ; Holliday, EG; Homuth, G; Horan, MA; Hottenga, JJ; de Jager, PL; Joshi, PK; Jugessur, A; Kaakinen, MA; Kähönen, M; Kanoni, S; Keltigangas-Järvinen, L; Kiemeney, LA; Kolcic, I; Koskinen, S; Kraja, AT; Kroh, M; Kutalik, Z; Latvala, A; Launer, LJ; Lebreton, MP; Levinson, DF; Lichtenstein, P; Lichtner, P; Liewald, DC; LifeLines Cohort Study; Loukola, A; Madden, PA; Mägi, R; Mäki-Opas, T; Marioni, RE; Marques-Vidal, P; Meddens, GA; McMahon, G; Meisinger, C; Meitinger, T; Milaneschi, Y; Milani, L; Montgomery, GW; Myhre, R; Nelson, CP; Nyholt, DR; Ollier, WE; Palotie, A; Paternoster, L; Pedersen, NL; Petrovic, KE; Porteous, DJ; Räikkönen, K; Ring, SM; Robino, A; Rostapshova, O; Rudan, I; Rustichini, A; Salomaa, V; Sanders, AR; Sarin, AP; Schmidt, H; Scott, RJ; Smith, BH; Smith, JA; Staessen, JA; Steinhagen-Thiessen, E; Strauch, K; Terracciano, A; Tobin, MD; Ulivi, S; Vaccargiu, S; Quaye, L; van Rooij, FJ; Venturini, C; Vinkhuyzen, AA; Völker, U; Völzke, H; Vonk, JM; Vozzi, D; Waage, J; Ware, EB; Willemsen, G; Attia, JR; Bennett, DA; Berger, K; Bertram, L; Bisgaard, H; Boomsma, DI; Borecki, IB; Bültmann, U; Chabris, CF; Cucca, F; Cusi, D; Deary, IJ; Dedoussis, GV; van Duijn, CM; Eriksson, JG; Franke, B; Franke, L; Gasparini, P; Gejman, PV; Gieger, C; Grabe, HJ; Gratten, J; Groenen, PJ; Gudnason, V; van der Harst, P; Hayward, C; Hinds, DA; Hoffmann, W; Hyppönen, E; Iacono, WG; Jacobsson, B; Järvelin, MR; Jöckel, KH; Kaprio, J; Kardia, SL; Lehtimäki, T; Lehrer, SF; Magnusson, PK; Martin, NG; McGue, M; Metspalu, A; Pendleton, N; Penninx, BW; Perola, M; Pirastu, N; Pirastu, M; Polasek, O; Posthuma, D; Power, C; Province, MA; Samani, NJ; Schlessinger, D; Schmidt, R; Sørensen, TI; Spector, TD; Stefansson, K; Thorsteinsdottir, U; Thurik, AR; Timpson, NJ; Tiemeier, H; Tung, JY; Uitterlinden, AG; Vitart, V; Vollenweider, P; Weir, DR; Wilson, JF; Wright, AF; Conley, DC; Krueger, RF; Davey Smith, G; Hofman, A; Laibson, DI; Medland, SE; Meyer, MN; Yang, J; Johannesson, M; Visscher, PM; Esko, T; Koellinger, PD; Cesarini, D; Benjamin, DJ Genome-wide association study identifies 74 loci associated with educational attainment.
Nature. 2016; 533(7604): 539-542. Doi: 10.1038/nature17671 [OPEN ACCESS]
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2015

Mora, M; Angelini, C; Bignami, F; Bodin, AM; Crimi, M; Di Donato, JH; Felice, A; Jaeger, C; Karcagi, V; LeCam, Y; Lynn, S; Meznaric, M; Moggio, M; Monaco, L; Politano, L; de la Paz, MP; Saker, S; Schneiderat, P; Ensini, M; Garavaglia, B; Gurwitz, D; Johnson, D; Muntoni, F; Puymirat, J; Reza, M; Voit, T; Baldo, C; Bricarelli, FD; Goldwurm, S; Merla, G; Pegoraro, E; Renieri, A; Zatloukal, K; Filocamo, M; Lochmüller, H The EuroBioBank Network: 10 years of hands-on experience of collaborative, transnational biobanking for rare diseases.
Eur J Hum Genet. 2015; 23(9):1116-1123 Doi: 10.1038/ejhg.2014.272 [OPEN ACCESS]
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2014

Emmert-Streib, F; de Matos Simoes, R; Glazko, G; McDade, S; Haibe-Kains, B; Holzinger, A; Dehmer, M; Campbell, F Functional and genetic analysis of the colon cancer network.
BMC Bioinformatics. 2014; 15 Suppl 6(16):S6-S6 Doi: 10.1186/1471-2105-15-S6-S6 [OPEN ACCESS]
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Göhler, A; Hetzer, A; Holtfreter, B; Geisel, MH; Schmidt, CO; Steinmetz, I; Kocher, T Quantitative molecular detection of putative periodontal pathogens in clinically healthy and periodontally diseased subjects.
PLoS One. 2014; 9(7):e99244-e99244 Doi: 10.1371/journal.pone.0099244 [OPEN ACCESS]
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Heidary, M; Auer, M; Ulz, P; Heitzer, E; Petru, E; Gasch, C; Riethdorf, S; Mauermann, O; Lafer, I; Pristauz, G; Lax, S; Pantel, K; Geigl, JB; Speicher, MR The dynamic range of circulating tumor DNA in metastatic breast cancer.
Breast Cancer Res. 2014; 16(4):421-421 Doi: 10.1186/s13058-014-0421-y [OPEN ACCESS]
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Prokesch, A; Smorlesi, A; Perugini, J; Manieri, M; Ciarmela, P; Mondini, E; Trajanoski, Z; Kristiansen, K; Giordano, A; Bogner-Strauss, JG; Cinti, S Molecular aspects of adipoepithelial transdifferentiation in mouse mammary gland.
Stem Cells. 2014; 32(10):2756-2766 Doi: 10.1002/stem.1756 [OPEN ACCESS]
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Shah, MH; Bhat, V; Shetty, JS; Kumar, A Whole exome sequencing identifies a novel splice-site mutation in ADAMTS17 in an Indian family with Weill-Marchesani syndrome.
Mol Vis. 2014; 20(4):790-796 (- Case Report) [OPEN ACCESS]
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Thompson, R; Johnston, L; Taruscio, D; Monaco, L; Béroud, C; Gut, IG; Hansson, MG; 't Hoen, PB; Patrinos, GP; Dawkins, H; Ensini, M; Zatloukal, K; Koubi, D; Heslop, E; Paschall, JE; Posada, M; Robinson, PN; Bushby, K; Lochmüller, H RD-Connect: an integrated platform connecting databases, registries, biobanks and clinical bioinformatics for rare disease research.
J Gen Intern Med. 2014; 29 Suppl 3(8):S780-S787 Doi: 10.1007/s11606-014-2908-8 [OPEN ACCESS]
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Wagner, A; Mayr, C; Bach, D; Illig, R; Plaetzer, K; Berr, F; Pichler, M; Neureiter, D; Kiesslich, T MicroRNAs associated with the efficacy of photodynamic therapy in biliary tract cancer cell lines.
Int J Mol Sci. 2014; 15(11):20134-20157 Doi: 10.3390/ijms151120134 [OPEN ACCESS]
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2013

Chamakuri, N; Kunisch, K; Plank, G On boundary stimulation and optimal boundary control of the bidomain equations.
Math Biosci. 2013; 245(2):206-215 Doi: 10.1016/j.mbs.2013.07.004 [OPEN ACCESS]
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Hartler, J; Tharakan, R; Köfeler, HC; Graham, DR; Thallinger, GG Bioinformatics tools and challenges in structural analysis of lipidomics MS/MS data.
Brief Bioinform. 2013; 14(3):375-390 Doi: 10.1093/bib/bbs030 [OPEN ACCESS]
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Patz, S; Trattnig, C; Grünbacher, G; Ebner, B; Gülly, C; Novak, A; Rinner, B; Leitinger, G; Absenger, M; Tomescu, OA; Thallinger, GG; Fasching, U; Wissa, S; Archelos-Garcia, J; Schäfer, U More than cell dust: microparticles isolated from cerebrospinal fluid of brain injured patients are messengers carrying mRNAs, miRNAs, and proteins.
J Neurotrauma. 2013; 30(14):1232-1242 Doi: 10.1089/neu.2012.2596
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Ubaida Mohien, C; Colquhoun, DR; Mathias, DK; Gibbons, JG; Armistead, JS; Rodriguez, MC; Rodriguez, MH; Edwards, NJ; Hartler, J; Thallinger, GG; Graham, DR; Martinez-Barnetche, J; Rokas, A; Dinglasan, RR A bioinformatics approach for integrated transcriptomic and proteomic comparative analyses of model and non-sequenced anopheline vectors of human malaria parasites.
Mol Cell Proteomics. 2013; 12(1):120-131 Doi: 10.1074/mcp.M112.019596 [OPEN ACCESS]
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2012

Hastings, J; Schulz, S Ontologies for human behavior analysis and their application to clinical data.
Int Rev Neurobiol. 2012; 103(4):89-107 Doi: 10.1016/B978-0-12-388408-4.00005-8
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2011

Auer-Grumbach, M; Weger, M; Fink-Puches, R; Papić, L; Fröhlich, E; Auer-Grumbach, P; El Shabrawi-Caelen, L; Schabhüttl, M; Windpassinger, C; Senderek, J; Budka, H; Trajanoski, S; Janecke, AR; Haas, A; Metze, D; Pieber, TR; Guelly, C Fibulin-5 mutations link inherited neuropathies, age-related macular degeneration and hyperelastic skin.
Brain. 2011; 134(Pt 6):1839-1852 Doi: 10.1093/brain/awr076 [OPEN ACCESS]
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Bhat, V; Girimaji, SC; Mohan, G; Arvinda, HR; Singhmar, P; Duvvari, MR; Kumar, A Mutations in WDR62, encoding a centrosomal and nuclear protein, in Indian primary microcephaly families with cortical malformations.
Clin Genet. 2011; 80(6): 532-540. Doi: 10.1111/j.1399-0004.2011.01686.x
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Drozdov, I; Svejda, B; Gustafsson, BI; Mane, S; Pfragner, R; Kidd, M; Modlin, IM Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia.
PLoS One. 2011; 6(8):e22457-e22457 Doi: 10.1371/journal.pone.0022457 [OPEN ACCESS]
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Niederer, SA; Kerfoot, E; Benson, AP; Bernabeu, MO; Bernus, O; Bradley, C; Cherry, EM; Clayton, R; Fenton, FH; Garny, A; Heidenreich, E; Land, S; Maleckar, M; Pathmanathan, P; Plank, G; Rodríguez, JF; Roy, I; Sachse, FB; Seemann, G; Skavhaug, O; Smith, NP Verification of cardiac tissue electrophysiology simulators using an N-version benchmark.
Philos Transact A Math Phys Eng Sci. 2011; 369(1954): 4331-4351. Doi: 10.1098/rsta.2011.0139 [OPEN ACCESS]
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2010

Kong, SW; Hu, YW; Ho, JWK; Ikeda, S; Polster, S; John, R; Hall, JL; Bisping, E; Pieske, B; dos Remedios, CG; Pu, WT Heart Failure-Associated Changes in RNA Splicing of Sarcomere Genes
Circ Cardiovasc Genet. 2010; 3(2):138-146 Doi: 10.1161/CIRCGENETICS.109.904698 [OPEN ACCESS]
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2009

Derler, I; Fahrner, M; Carugo, O; Muik, M; Bergsmann, J; Schindl, R; Frischauf, I; Eshaghi, S; Romanin, C Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant.
J Biol Chem. 2009; 284(23): 15903-15915. Doi: 10.1074/jbc.M808312200 [OPEN ACCESS]
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Prokesch, A; Hackl, H; Hakim-Weber, R; Bornstein, SR; Trajanoski, Z Novel insights into adipogenesis from omics data.
Curr Med Chem. 2009; 16(23): 2952-2964. Doi: 10.2174/092986709788803132 [OPEN ACCESS]
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Schweiger, MR; Kerick, M; Timmermann, B; Albrecht, MW; Borodina, T; Parkhomchuk, D; Zatloukal, K; Lehrach, H Genome-wide massively parallel sequencing of formaldehyde fixed-paraffin embedded (FFPE) tumor tissues for copy-number- and mutation-analysis.
PLoS One. 2009; 4(5): e5548-e5548. Doi: 10.1371/journal.pone.0005548 [OPEN ACCESS]
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2008

Beisswanger, E; Lee, V; Kim, JJ; Rebholz-Schuhmann, D; Splendiani, A; Dameron, O; Schulz, S; Hahn, U Gene Regulation Ontology (GRO): design principles and use cases.
Stud Health Technol Inform. 2008; 136:9-14
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Viertler, C; Zatloukal, K Biobanking and Biomolecular Resources Research Infrastructure (BBMRI). Implications for pathology
Pathologe. 2008; 29 Suppl 2(10):210-213 Doi: 10.1007/s00292-008-1048-5
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2007

Hahn, U; Schulz, S Ontological foundations for biomedical sciences.
Artif Intell Med. 2007; 39(3):179-182 Doi: 10.1016/j.artmed.2006.12.006
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Schulz, S; Hahn, U Towards the ontological foundations of symbolic biological theories.
Artif Intell Med. 2007; 39(3):237-250 Doi: 10.1016/j.artmed.2006.12.001
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Vigmond, EJ; Weber Dos Santos, R; Prassl, AJ; Deo, M; Plank, G Solvers for the cardiac bidomain equations.
Prog Biophys Mol Biol. 2007; 96(1-3): 3-18. Doi: 10.1016/j.pbiomolbio.2007.07.012 [OPEN ACCESS]
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2006

Mátyás, G; Arnold, E; Carrel, T; Baumgartner, D; Boileau, C; Berger, W; Steinmann, B Identification and in silico analyses of novel TGFBR1 and TGFBR2 mutations in Marfan syndrome-related disorders.
Hum Mutat. 2006; 27(8):760-769 Doi: 10.1002/humu.20353
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2005

Wheeler, DL; Barrett, T; Benson, DA; Bryant, SH; Canese, K; Church, DM; DiCuccio, M; Edgar, R; Federhen, S; Helmberg, W; Kenton, DL; Khovayko, O; Lipman, DJ; Madden, TL; Maglott, DR; Ostell, J; Pontius, JU; Pruitt, KD; Schuler, GD; Schriml, LM; Sequeira, E; Sherry, ST; Sirotkin, K; Starchenko, G; Suzek, TO; Tatusov, R; Tatusova, TA; Wagner, L; Yaschenko, E Database resources of the National Center for Biotechnology Information.
Nucleic Acids Res. 2005; 33(Database issue):D39-D45 Doi: 10.1093/nar/gki062 [OPEN ACCESS]
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2004

Schimek, MG Penalized binary regression for gene expression profiling.
METHODS INFORM MED. 2004; 43(5): 439-444. Doi: 10.1267/METH04050439
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Wheeler, DL; Church, DM; Edgar, R; Federhen, S; Helmberg, W; Madden, TL; Pontius, JU; Schuler, GD; Schriml, LM; Sequeira, E; Suzek, TO; Tatusova, TA; Wagner, L Database resources of the National Center for Biotechnology Information: update.
Nucleic Acids Res. 2004; 32(Data): D35-D40. Doi: 10.1093/nar/gkh073 [OPEN ACCESS]
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2003

Hahn, U; Schulz, S Towards a broad-coverage biomedical ontology based on description logics.
Pac Symp Biocomput. 2003; 90(3):577-588 [OPEN ACCESS]
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2000

Feolo, M; Helmberg, W; Sherry, S; Maglott, DR NCBI genetic resources supporting immunogenetic research.
Rev Immunogenet. 2000; 2(4): 461-467.
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