Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: COLORECTAL NEOPLASMS - GENETICS , . Treffer: 71

2018

Deshwar, A; Margonis, GA; Andreatos, N; Barbon, C; Wang, J; Buettner, S; Wagner, D; Sasaki, K; Beer, A; Løes, IM; Pikoulis, E; Damaskos, C; Garmpis, N; Kamphues, K; He, J; Kaczirek, K; Poultsides, G; Lønning, PE; Mischinger, HJ; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series.
Anticancer Res. 2018; 38(5):2891-2895 (- Case Report) [OPEN ACCESS]
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2017

Cătană, CS; Pichler, M; Giannelli, G; Mader, RM; Berindan-Neagoe, I Non-coding RNAs, the Trojan horse in two-way communication between tumor and stroma in colorectal and hepatocellular carcinoma.
Oncotarget. 2017; 8(17):29519-29534 [OPEN ACCESS]
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El-Heliebi, A; Kashofer, K; Fuchs, J; Jahn, SW; Viertler, C; Matak, A; Sedlmayr, P; Hoefler, G Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.
Histochem Cell Biol. 2017; 148(2):105-115 [OPEN ACCESS]
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Goblirsch, M; Richtig, G; Slaby, O; Berindan-Neagoe, I; Gerger, A; Pichler, M MicroRNAs as a tool to aid stratification of colorectal cancer patients and to guide therapy.
Pharmacogenomics. 2017; 18(10):1027-1038
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Kriegshäuser, G; Enko, D; Zitt, M; Oberwalder, M; Oberkanins, C; Öfner, D; Zeillinger, R; Maximilian Müller, H Comparison of a prototype reverse hybridization assay and MethyLight for detection of SFRP2 promotor methylation in fecal DNA.
Int J Biol Markers. 2017; 32(4):e467-e470-e467-e470 [OPEN ACCESS]
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Pichler, M; Stiegelbauer, V; Vychytilova-Faltejskova, P; Ivan, C; Ling, H; Winter, E; Zhang, X; Goblirsch, M; Wulf-Goldenberg, A; Ohtsuka, M; Haybaeck, J; Svoboda, M; Okugawa, Y; Gerger, A; Hoefler, G; Goel, A; Slaby, O; Calin, GA Genome-Wide miRNA Analysis Identifies miR-188-3p as a Novel Prognostic Marker and Molecular Factor Involved in Colorectal Carcinogenesis.
Clin Cancer Res. 2017; 23(5):1323-1333 [OPEN ACCESS]
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Plath, J; Siebenhofer, A; Koné, I; Hechtner, M; Schulz-Rothe, S; Beyer, M; Gerlach, FM; Guethlin, C Frequency of a positive family history of colorectal cancer in general practice: a cross-sectional study.
Fam Pract. 2017; 34(1):30-35 [OPEN ACCESS]
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Rigoutsos, I; Lee, SK; Nam, SY; Anfossi, S; Pasculli, B; Pichler, M; Jing, Y; Rodriguez-Aguayo, C; Telonis, AG; Rossi, S; Ivan, C; Catela Ivkovic, T; Fabris, L; Clark, PM; Ling, H; Shimizu, M; Redis, RS; Shah, MY; Zhang, X; Okugawa, Y; Jung, EJ; Tsirigos, A; Huang, L; Ferdin, J; Gafà, R; Spizzo, R; Nicoloso, MS; Paranjape, AN; Shariati, M; Tiron, A; Yeh, JJ; Teruel-Montoya, R; Xiao, L; Melo, SA; Menter, D; Jiang, ZQ; Flores, ER; Negrini, M; Goel, A; Bar-Eli, M; Mani, SA; Liu, CG; Lopez-Berestein, G; Berindan-Neagoe, I; Esteller, M; Kopetz, S; Lanza, G; Calin, GA N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration.
Genome Biol. 2017; 18(1):98-98 [OPEN ACCESS]
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Rössler, O; Betge, J; Harbaum, L; Mrak, K; Tschmelitsch, J; Langner, C Tumor size, tumor location, and antitumor inflammatory response are associated with lymph node size in colorectal cancer patients.
Mod Pathol. 2017; 30(6):897-904 [OPEN ACCESS]
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Schütte, M; Risch, T; Abdavi-Azar, N; Boehnke, K; Schumacher, D; Keil, M; Yildiriman, R; Jandrasits, C; Borodina, T; Amstislavskiy, V; Worth, CL; Schweiger, C; Liebs, S; Lange, M; Warnatz, HJ; Butcher, LM; Barrett, JE; Sultan, M; Wierling, C; Golob-Schwarzl, N; Lax, S; Uranitsch, S; Becker, M; Welte, Y; Regan, JL; Silvestrov, M; Kehler, I; Fusi, A; Kessler, T; Herwig, R; Landegren, U; Wienke, D; Nilsson, M; Velasco, JA; Garin-Chesa, P; Reinhard, C; Beck, S; Schäfer, R; Regenbrecht, CR; Henderson, D; Lange, B; Haybaeck, J; Keilholz, U; Hoffmann, J; Lehrach, H; Yaspo, ML Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Nat Commun. 2017; 8(2):14262-14262 [OPEN ACCESS]
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Shen, P; Pichler, M; Chen, M; Calin, GA; Ling, H To Wnt or Lose: The Missing Non-Coding Linc in Colorectal Cancer.
Int J Mol Sci. 2017; 18(9): [OPEN ACCESS]
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Stiegelbauer, V; Vychytilova-Faltejskova, P; Karbiener, M; Pehserl, AM; Reicher, A; Resel, M; Heitzer, E; Ivan, C; Bullock, M; Ling, H; Deutsch, A; Wulf-Goldenberg, A; Adiprasito, JB; Stoeger, H; Haybaeck, J; Svoboda, M; Stotz, M; Hoefler, G; Slaby, O; Calin, GA; Gerger, A; Pichler, M miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5.
Clin Cancer Res. 2017; 23(17):5255-5266 [OPEN ACCESS]
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Taniguchi, K; Moroishi, T; de Jong, PR; Krawczyk, M; Grebbin, BM; Luo, H; Xu, RH; Golob-Schwarzl, N; Schweiger, C; Wang, K; Di Caro, G; Feng, Y; Fearon, ER; Raz, E; Kenner, L; Farin, HF; Guan, KL; Haybaeck, J; Datz, C; Zhang, K; Karin, M YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
Proc Natl Acad Sci U S A. 2017; 114(7):1643-1648 [OPEN ACCESS]
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2016

Bonin, S; Donada, M; Bussolati, G; Nardon, E; Annaratone, L; Pichler, M; Chiaravalli, AM; Capella, C; Hoefler, G; Stanta, G A synonymous EGFR polymorphism predicting responsiveness to anti-EGFR therapy in metastatic colorectal cancer patients.
Tumour Biol. 2016; 37(6):7295-7303
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Ling, H; Pickard, K; Ivan, C; Isella, C; Ikuo, M; Mitter, R; Spizzo, R; Bullock, M; Braicu, C; Pileczki, V; Vincent, K; Pichler, M; Stiegelbauer, V; Hoefler, G; Almeida, MI; Hsiao, A; Zhang, X; Primrose, J; Packham, G; Liu, K; Bojja, K; Gafà, R; Xiao, L; Rossi, S; Song, JH; Vannini, I; Fanini, F; Kopetz, S; Zweidler-McKay, P; Wang, X; Ionescu, C; Irimie, A; Fabbri, M; Lanza, G; Hamilton, SR; Berindan-Neagoe, I; Medico, E; Mirnezami, A; Calin, GA; Nicoloso, MS The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.
Gut. 2016; 65(6):977-989 [OPEN ACCESS]
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Mlecnik, B; Bindea, G; Kirilovsky, A; Angell, HK; Obenauf, AC; Tosolini, M; Church, SE; Maby, P; Vasaturo, A; Angelova, M; Fredriksen, T; Mauger, S; Waldner, M; Berger, A; Speicher, MR; Pagès, F; Valge-Archer, V; Galon, J The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.
Sci Transl Med. 2016; 8(327):327ra26-327ra26
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Ohtsuka, M; Ling, H; Ivan, C; Pichler, M; Matsushita, D; Goblirsch, M; Stiegelbauer, V; Shigeyasu, K; Zhang, X; Chen, M; Vidhu, F; Bartholomeusz, GA; Toiyama, Y; Kusunoki, M; Doki, Y; Mori, M; Song, S; Gunther, JR; Krishnan, S; Slaby, O; Goel, A; Ajani, JA; Radovich, M; Calin, GA H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.
EBioMedicine. 2016; 13(3):113-124 [OPEN ACCESS]
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Pehserl, AM; Ress, AL; Stanzer, S; Resel, M; Karbiener, M; Stadelmeyer, E; Stiegelbauer, V; Gerger, A; Mayr, C; Scheideler, M; Hutterer, GC; Bauernhofer, T; Kiesslich, T; Pichler, M Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells.
Int J Mol Sci. 2016; 17(12): [OPEN ACCESS]
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Perakis, SO; Thomas, JE; Pichler, M Non-coding RNAs Enabling Prognostic Stratification and Prediction of Therapeutic Response in Colorectal Cancer Patients.
Adv Exp Med Biol. 2016; 937(4):183-204
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Weber, ML; Schneider, DT; Offenmüller, S; Kaatsch, P; Einsiedel, HG; Benesch, M; Claviez, A; Ebinger, M; Kramm, C; Kratz, C; Lawlor, J; Leuschner, I; Merkel, S; Metzler, M; Nustede, R; Petsch, S; Seeger, KH; Schlegel, PG; Suttorp, M; Zolk, O; Brecht, IB Pediatric Colorectal Carcinoma is Associated With Excellent Outcome in the Context of Cancer Predisposition Syndromes.
Pediatr Blood Cancer. 2016; 63(4):611-617
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2015

Bochis, OV; Irimie, A; Pichler, M; Berindan-Neagoe, I The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer.
J Gastrointestin Liver Dis. 2015; 24(2):225-234 [OPEN ACCESS]
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Kaczirek, K; Ciuleanu, TE; Vrbanec, D; Marton, E; Messinger, D; Liegl-Atzwanger, B; Wrba, F; Knittelfelder, R; Lindner, E; Zielinski, CC; Streubel, B; Brodowicz, T FOLFOX4 Plus Cetuximab for Patients With Previously Untreated Metastatic Colorectal Cancer According to Tumor RAS and BRAF Mutation Status: Updated Analysis of the CECOG/CORE 1.2.002 Study.
Clin Colorectal Cancer. 2015; 14(2):91-98
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Ress, AL; Perakis, S; Pichler, M microRNAs and Colorectal Cancer.
Adv Exp Med Biol. 2015; 889(6):89-103
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Ress, AL; Stiegelbauer, V; Winter, E; Schwarzenbacher, D; Kiesslich, T; Lax, S; Jahn, S; Deutsch, A; Bauernhofer, T; Ling, H; Samonigg, H; Gerger, A; Hoefler, G; Pichler, M MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients.
Mol Carcinog. 2015; 54(11):1442-1450
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Setaffy, L; Langner, C Microsatellite instability in colorectal cancer: clinicopathological significance.
Pol J Pathol. 2015; 66(3):203-218 [OPEN ACCESS]
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Smolle, MA; Pichler, M; Haybaeck, J; Gerger, A Genetic markers of recurrence in colorectal cancer.
Pharmacogenomics. 2015; 16(11):1315-1328
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Thomas, J; Ohtsuka, M; Pichler, M; Ling, H MicroRNAs: Clinical Relevance in Colorectal Cancer.
Int J Mol Sci. 2015; 16(12):28063-28076 [OPEN ACCESS]
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2014

Benhaim, L; Gerger, A; Bohanes, P; Paez, D; Wakatsuki, T; Yang, D; Labonte, MJ; Ning, Y; El-Khoueiry, R; Loupakis, F; Zhang, W; Laurent-Puig, P; Lenz, HJ Gender-specific profiling in SCN1A polymorphisms and time-to-recurrence in patients with stage II/III colorectal cancer treated with adjuvant 5-fluoruracil chemotherapy.
Pharmacogenomics J. 2014; 14(2):135-141
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Mohan, S; Heitzer, E; Ulz, P; Lafer, I; Lax, S; Auer, M; Pichler, M; Gerger, A; Eisner, F; Hoefler, G; Bauernhofer, T; Geigl, JB; Speicher, MR Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing.
PLoS Genet. 2014; 10(3):e1004271-e1004271 [OPEN ACCESS]
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Pichler, M; Ress, AL; Winter, E; Stiegelbauer, V; Karbiener, M; Schwarzenbacher, D; Scheideler, M; Ivan, C; Jahn, SW; Kiesslich, T; Gerger, A; Bauernhofer, T; Calin, GA; Hoefler, G MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients.
Br J Cancer. 2014; 110(6):1614-1621 [OPEN ACCESS]
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Rau, TT; Agaimy, A; Gehoff, A; Geppert, C; Jung, K; Knobloch, K; Langner, C; Lugli, A; Groenbus-Lurkin, I; Nagtegaal, ID; Rüschoff, J; Saegert, X; Sarbia, M; Schneider-Stock, R; Vieth, M; Zwarthoff, EC; Hartmann, A Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics.
Virchows Arch. 2014; 464(6):663-672
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Ress, AL; Stiegelbauer, V; Schwarzenbacher, D; Deutsch, A; Perakis, S; Ling, H; Ivan, C; Calin, GA; Rinner, B; Gerger, A; Pichler, M Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer.
Oncotarget. 2014; 5(18):8492-8502 [OPEN ACCESS]
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Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Nojima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Heitzer, E; Geigl, JB; Windpassinger, C; Hoefler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.
Nat Commun. 2014; 5(10):5191-5191 [OPEN ACCESS]
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Stiegelbauer, V; Perakis, S; Deutsch, A; Ling, H; Gerger, A; Pichler, M MicroRNAs as novel predictive biomarkers and therapeutic targets in colorectal cancer.
World J Gastroenterol. 2014; 20(33):11727-11735 [OPEN ACCESS]
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2013

Bindea, G; Mlecnik, B; Tosolini, M; Kirilovsky, A; Waldner, M; Obenauf, AC; Angell, H; Fredriksen, T; Lafontaine, L; Berger, A; Bruneval, P; Fridman, WH; Becker, C; Pagès, F; Speicher, MR; Trajanoski, Z; Galon, J Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.
Immunity. 2013; 39(4):782-795 [OPEN ACCESS]
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Buxhofer-Ausch, V; Ausch, C; Zeillinger, R; Oberkanins, C; Dandachi, N; Reiner-Concin, A; Kriegshäuser, G Duplex reverse-hybridization assay for the simultaneous detection of KRAS/BRAF mutations in FFPE-extracted genomic DNA from colorectal cancer specimens.
Dis Markers. 2013; 34(3):171-177 [OPEN ACCESS]
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Dijkstra, JR; Heideman, DA; Meijer, GA; Boers, JE; 't Hart, NA; Diebold, J; Hirschmann, A; Hoefler, G; Winter, G; Miltenberger-Miltenyi, G; Pereira, SV; Richman, SD; Quirke, P; Rouleau, EL; Guinebretiere, JM; Tejpar, S; Biesmans, B; van Krieken, JH KRAS mutation analysis on low percentage of colon cancer cells: the importance of quality assurance.
Virchows Arch. 2013; 462(1):39-46
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Gasch, C; Bauernhofer, T; Pichler, M; Langer-Freitag, S; Reeh, M; Seifert, AM; Mauermann, O; Izbicki, JR; Pantel, K; Riethdorf, S Heterogeneity of Epidermal Growth Factor Receptor Status and Mutations of KRAS/PIK3CA in Circulating Tumor Cells of Patients with Colorectal Cancer.
Clin Chem. 2013; 59(1):252-260 [OPEN ACCESS]
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Heitzer, E; Auer, M; Gasch, C; Pichler, M; Ulz, P; Hoffmann, EM; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Lackner, C; Höfler, G; Eisner, F; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing.
Cancer Res. 2013; 73(10):2965-2975 [OPEN ACCESS]
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Heitzer, E; Auer, M; Hoffmann, EM; Pichler, M; Gasch, C; Ulz, P; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Mohan, S; Pristauz, G; Lackner, C; Höfler, G; Eisner, F; Petru, E; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer.
Int J Cancer. 2013; 133(2):346-356 [OPEN ACCESS]
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Röhr, C; Kerick, M; Fischer, A; Kühn, A; Kashofer, K; Timmermann, B; Daskalaki, A; Meinel, T; Drichel, D; Börno, ST; Nowka, A; Krobitsch, S; McHardy, AC; Kratsch, C; Becker, T; Wunderlich, A; Barmeyer, C; Viertler, C; Zatloukal, K; Wierling, C; Lehrach, H; Schweiger, MR High-throughput miRNA and mRNA sequencing of paired colorectal normal, tumor and metastasis tissues and bioinformatic modeling of miRNA-1 therapeutic applications.
PLoS One. 2013; 8(7):e67461-e67461 [OPEN ACCESS]
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Szkandera, J; Winder, T; Stotz, M; Weissmueller, M; Langsenlehner, T; Pichler, M; Samonigg, H; Renner, W; Gerger, A; Absenger, G A common gene variant in PLS3 predicts colon cancer recurrence in women.
Tumour Biol. 2013; 34(4):2183-2188
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2012

Dijkstra, JR; Opdam, FJ; Boonyaratanakornkit, J; Schönbrunner, ER; Shahbazian, M; Edsjö, A; Hoefler, G; Jung, A; Kotsinas, A; Gorgoulis, VG; Lpez-Ros, F; de Stricker, K; Rouleau, E; Biesmans, B; van Krieken, JH Implementation of formalin-fixed, paraffin-embedded cell line pellets as high-quality process controls in quality assessment programs for KRAS mutation analysis.
J Mol Diagn. 2012; 14(3):187-191 [OPEN ACCESS]
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van Krieken, JH; Hoefler, G The times have changed: molecular pathology is here to stay. A commentary on: analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma, by Lee et al. In this issue.
VIRCHOWS ARCH. 2012; 460(2): 129-130. [OPEN ACCESS]
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2011

Gerger, A; El-Khoueiry, A; Zhang, W; Yang, D; Singh, H; Bohanes, P; Ning, Y; Winder, T; Labonte, MJ; Wilson, PM; Benhaim, L; Paez, D; El-Khoueiry, R; Absenger, G; Lenz, HJ Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.
Clin Cancer Res. 2011; 17(17):5783-5792 [OPEN ACCESS]
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Hofmann, G; Langsenlehner, U; Langsenlehner, T; Glehr, M; Gerger, A; Absenger, G; Szkandera, J; Fuerst, F; Samonigg, H; Krippl, P; Renner, W Single nucleotide polymorphisms of integrin alpha-2 and beta-3 genes are not associated with relapse-free and overall survival in colorectal cancer patients.
Anticancer Res. 2011; 31(4):1373-1377
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Langner, C Non-serrated precursor lesions of colorectal tumours.
Pathologe. 2011; 32 Suppl 2(1):206-210
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Winder, T; Bohanes, P; Zhang, W; Yang, D; Power, DG; Ning, Y; Gerger, A; Wilson, PM; Tang, LH; Shah, M; Lee, AS; Lenz, HJ GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.
Ann Oncol. 2011; 22(11):2431-2439 [OPEN ACCESS]
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2010

Knechtel, G; Szkandera, J; Stotz, M; Hofmann, G; Langsenlehner, U; Krippl, P; Samonigg, H; Renner, W; Langner, C; Dehchamani, D; Gerger, A Single nucleotide polymorphisms in the hypoxia-inducible factor-1 gene and colorectal cancer risk.
Mol Carcinog. 2010; 49(9):805-809
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Szkandera, J; Knechtel, G; Stotz, M; Hofmann, G; Langsenlehner, U; Krippl, P; Langsenlehner, T; Dehchamani, D; Samonigg, H; Renner, W; Gerger, A Association of hypoxia-inducible factor 1-alpha gene polymorphisms and colorectal cancer prognosis.
Anticancer Res. 2010; 30(6):2393-2397
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