Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: CELL LINE, TUMOR - , . Treffer: 340

2017

Arzt, L; Halbwedl, I; Gogg-Kamerer, M; Popper, HH Signal Transducer and Activator of Transcription 1 (STAT1) Knock-down Induces Apoptosis in Malignant Pleural Mesothelioma.
Pathol Oncol Res. 2017; 23(3):595-605 [OPEN ACCESS]
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Bayraktar, R; Pichler, M; Kanlikilicer, P; Ivan, C; Bayraktar, E; Kahraman, N; Aslan, B; Oguztuzun, S; Ulasli, M; Arslan, A; Calin, G; Lopez-Berestein, G; Ozpolat, B MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase.
Oncotarget. 2017; 8(7):11641-11658 [OPEN ACCESS]
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Castellani, C; Singer, G; Kaiser, M; Kaiser, T; Huang, J; Sperl, D; Kashofer, K; Fauler, G; Guertl-Lackner, B; Höfler, G; Till, H Neuroblastoma causes alterations of the intestinal microbiome, gut hormones, inflammatory cytokines, and bile acid composition.
Pediatr Blood Cancer. 2017; 64(8):
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Chao, MP; Gentles, AJ; Chatterjee, S; Lan, F; Reinisch, A; Corces, MR; Xavy, S; Shen, J; Haag, D; Chanda, S; Sinha, R; Morganti, RM; Nishimura, T; Ameen, M; Wu, H; Wernig, M; Wu, JC; Majeti, R Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Cell Stem Cell. 2017; 20(3): 329-344. [OPEN ACCESS]
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Deutsch, AJA; Rinner, B; Pichler, M; Prochazka, K; Pansy, K; Bischof, M; Fechter, K; Hatzl, S; Feichtinger, J; Wenzl, K; Frisch, MT; Stiegelbauer, V; Prokesch, A; Krogsdam, A; Sill, H; Thallinger, GG; Greinix, HT; Wang, C; Beham-Schmid, C; Neumeister, P NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.
Cancer Res. 2017; 77(9):2375-2386 [OPEN ACCESS]
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Ding, X; Su, Y; Wang, C; Zhang, F; Chen, K; Wang, Y; Li, M; Wang, W Synergistic Suppression of Tumor Angiogenesis by the Co-delivering of Vascular Endothelial Growth Factor Targeted siRNA and Candesartan Mediated by Functionalized Carbon Nanovectors.
ACS Appl Mater Interfaces. 2017; 9(28): 23353-23369.
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Edlinger, L; Berger-Becvar, A; Menzl, I; Hoermann, G; Greiner, G; Grundschober, E; Bago-Horvath, Z; Al-Zoughbi, W; Hoefler, G; Brostjan, C; Gille, L; Moriggl, R; Spittler, A; Sexl, V; Hoelbl-Kovacic, A Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1.
Br J Haematol. 2017; 179(2):229-241 [OPEN ACCESS]
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El-Heliebi, A; Kashofer, K; Fuchs, J; Jahn, SW; Viertler, C; Matak, A; Sedlmayr, P; Hoefler, G Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.
Histochem Cell Biol. 2017; 148(2):105-115 [OPEN ACCESS]
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Enzenhofer, E; Kadletz, L; Stanisz, I; Kotowski, U; Seemann, R; Schmid, R; Thurnher, D; Heiduschka, G Effect of the histone deacetylase inhibitor resminostat on head and neck squamous cell carcinoma cell lines.
Head Neck. 2017; 39(5):900-907
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Görtz, M; Galli, U; Longerich, T; Zöller, M; Erb, U; Schemmer, P De novo synthesis of C4.4A in hepatocellular carcinoma promotes migration and invasion of tumor cells.
Oncol Rep. 2017; 38(5):2697-2704 [OPEN ACCESS]
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Hlavaty, J; Wolfesberger, B; Hauck, M; Obermayer-Pietsch, B; Fuchs-Baumgartinger, A; Miller, I; Walter, I Ezrin and moesin expression in canine and feline osteosarcoma.
Histol Histopathol. 2017; 32(8):805-816
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Jäger, D; Barth, TFE; Brüderlein, S; Scheuerle, A; Rinner, B; von Witzleben, A; Lechel, A; Meyer, P; Mayer-Steinacker, R; Baer, AV; Schultheiss, M; Wirtz, CR; Möller, P; Mellert, K HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas.
Sci Rep. 2017; 7(1):2032-2032 [OPEN ACCESS]
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Kroneis, T; Jonasson, E; Andersson, D; Dolatabadi, S; Ståhlberg, A Global preamplification simplifies targeted mRNA quantification.
Sci Rep. 2017; 7(2):45219-45219 [OPEN ACCESS]
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Lin, S; Hoffmann, K; Gao, C; Petrulionis, M; Herr, I; Schemmer, P Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma.
J PINEAL RES. 2017; 62(3):
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Lohberger, B; Stuendl, N; Leithner, A; Rinner, B; Sauer, S; Kashofer, K; Liegl-Atzwanger, B Establishment of a novel cellular model for myxofibrosarcoma heterogeneity.
Sci Rep. 2017; 7(9):44700-44700 [OPEN ACCESS]
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Nelson, ME; Lahiri, S; Chow, JD; Byrne, FL; Hargett, SR; Breen, DS; Olzomer, EM; Wu, LE; Cooney, GJ; Turner, N; James, DE; Slack-Davis, JK; Lackner, C; Caldwell, SH; Hoehn, KL Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.
Nat Commun. 2017; 8(6):14689-14689 [OPEN ACCESS]
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Pfanzagl, B; Mechtcheriakova, D; Meshcheryakova, A; Aberle, SW; Pfragner, R; Jensen-Jarolim, E Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R.
Sci Rep. 2017; 7(1):1313-1313 [OPEN ACCESS]
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Planells-Palop, V; Hazazi, A; Feichtinger, J; Jezkova, J; Thallinger, G; Alsiwiehri, NO; Almutairi, M; Parry, L; Wakeman, JA; McFarlane, RJ Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis.
Mol Cancer. 2017; 16(1): 84-84. [OPEN ACCESS]
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Račkauskas, R; Zhou, D; Ūselis, S; Strupas, K; Herr, I; Schemmer, P Sulforaphane sensitizes human cholangiocarcinoma to cisplatin via the downregulation of anti-apoptotic proteins.
Oncol Rep. 2017; 37(6):3660-3666
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Richtig, G; Aigelsreiter, A; Schwarzenbacher, D; Ress, AL; Adiprasito, JB; Stiegelbauer, V; Hoefler, G; Schauer, S; Kiesslich, T; Kornprat, P; Winder, T; Eisner, F; Gerger, A; Stoeger, H; Stauber, R; Lackner, C; Pichler, M SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types.
PLoS One. 2017; 12(11):e0187814-e0187814 [OPEN ACCESS]
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Riedl, A; Schlederer, M; Pudelko, K; Stadler, M; Walter, S; Unterleuthner, D; Unger, C; Kramer, N; Hengstschläger, M; Kenner, L; Pfeiffer, D; Krupitza, G; Dolznig, H Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses.
J Cell Sci. 2017; 130(1):203-218 [OPEN ACCESS]
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Rinner, B; Gandolfi, G; Meditz, K; Frisch, MT; Wagner, K; Ciarrocchi, A; Torricelli, F; Koivuniemi, R; Niklander, J; Liegl-Atzwanger, B; Lohberger, B; Heitzer, E; Ghaffari-Tabrizi-Wizsy, N; Zweytick, D; Zalaudek, I MUG-Mel2, a novel highly pigmented and well characterized NRAS mutated human melanoma cell line.
Sci Rep. 2017; 7(1):2098-2098 [OPEN ACCESS]
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Ritter, C; Fan, K; Paschen, A; Reker Hardrup, S; Ferrone, S; Nghiem, P; Ugurel, S; Schrama, D; Becker, JC Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma.
Sci Rep. 2017; 7(1):2290-2290 [OPEN ACCESS]
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Salar-Behzadi, S; Wu, S; Mercuri, A; Meindl, C; Stranzinger, S; Fröhlich, E Effect of the pulmonary deposition and in vitro permeability on the prediction of plasma levels of inhaled budesonide formulation.
Int J Pharm. 2017; 532(1):337-344
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Sheffield, NC; Pierron, G; Klughammer, J; Datlinger, P; Schönegger, A; Schuster, M; Hadler, J; Surdez, D; Guillemot, D; Lapouble, E; Freneaux, P; Champigneulle, J; Bouvier, R; Walder, D; Ambros, IM; Hutter, C; Sorz, E; Amaral, AT; de Álava, E; Schallmoser, K; Strunk, D; Rinner, B; Liegl-Atzwanger, B; Huppertz, B; Leithner, A; de Pinieux, G; Terrier, P; Laurence, V; Michon, J; Ladenstein, R; Holter, W; Windhager, R; Dirksen, U; Ambros, PF; Delattre, O; Kovar, H; Bock, C; Tomazou, EM DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.
Nat Med. 2017; 23(3):386-395 [OPEN ACCESS]
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Sinha, S; Thomas, D; Chan, S; Gao, Y; Brunen, D; Torabi, D; Reinisch, A; Hernandez, D; Chan, A; Rankin, EB; Bernards, R; Majeti, R; Dill, DL Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data.
Nat Commun. 2017; 8(2):15580-15580 [OPEN ACCESS]
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Stiegelbauer, V; Vychytilova-Faltejskova, P; Karbiener, M; Pehserl, AM; Reicher, A; Resel, M; Heitzer, E; Ivan, C; Bullock, M; Ling, H; Deutsch, A; Wulf-Goldenberg, A; Adiprasito, JB; Stoeger, H; Haybaeck, J; Svoboda, M; Stotz, M; Hoefler, G; Slaby, O; Calin, GA; Gerger, A; Pichler, M miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5.
Clin Cancer Res. 2017; 23(17):5255-5266 [OPEN ACCESS]
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Taniguchi, K; Moroishi, T; de Jong, PR; Krawczyk, M; Grebbin, BM; Luo, H; Xu, RH; Golob-Schwarzl, N; Schweiger, C; Wang, K; Di Caro, G; Feng, Y; Fearon, ER; Raz, E; Kenner, L; Farin, HF; Guan, KL; Haybaeck, J; Datz, C; Zhang, K; Karin, M YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
Proc Natl Acad Sci U S A. 2017; 114(7):1643-1648 [OPEN ACCESS]
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Tetyczka, C; Griesbacher, M; Absenger-Novak, M; Fröhlich, E; Roblegg, E Development of nanostructured lipid carriers for intraoral delivery of Domperidone.
Int J Pharm. 2017; 526(1-2):188-198
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Trapp, EK; Majunke, L; Zill, B; Sommer, H; Andergassen, U; Koch, J; Harbeck, N; Mahner, S; Friedl, TWP; Janni, W; Rack, B; Alunni-Fabbroni, M LKB1 pro-oncogenic activity triggers cell survival in circulating tumor cells.
Mol Oncol. 2017; 11(11):1508-1526 [OPEN ACCESS]
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Triebl, A; Trötzmüller, M; Hartler, J; Stojakovic, T; Köfeler, HC Lipidomics by ultrahigh performance liquid chromatography-high resolution mass spectrometry and its application to complex biological samples.
J CHROMATOGR B. 2017; 1053(4): 72-80. [OPEN ACCESS]
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Wohlkoenig, C; Leithner, K; Olschewski, A; Olschewski, H; Hrzenjak, A TR3 is involved in hypoxia-induced apoptosis resistance in lung cancer cells downstream of HIF-1α.
Lung Cancer. 2017; 111(3):15-22
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2016

Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591
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Boehnke, K; Iversen, PW; Schumacher, D; Lallena, MJ; Haro, R; Amat, J; Haybaeck, J; Liebs, S; Lange, M; Schäfer, R; Regenbrecht, CR; Reinhard, C; Velasco, JA Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures.
J Biomol Screen. 2016; 21(9):931-941 [OPEN ACCESS]
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Fan, P; Liu, L; Yin, Y; Zhao, Z; Zhang, Y; Amponsah, PS; Xiao, X; Bauer, N; Abukiwan, A; Nwaeburu, CC; Gladkich, J; Gao, C; Schemmer, P; Gross, W; Herr, I MicroRNA-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer.
Cancer Lett. 2016; 373(1):130-137
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Fan, P; Zhang, Y; Liu, L; Zhao, Z; Yin, Y; Xiao, X; Bauer, N; Gladkich, J; Mattern, J; Gao, C; Schemmer, P; Gross, W; Herr, I Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.
Cell Death Dis. 2016; 7(6):e2246-e2246 [OPEN ACCESS]
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Gellner, V; Tomazic, PV; Lohberger, B; Meditz, K; Heitzer, E; Mokry, M; Koele, W; Leithner, A; Liegl-Atzwanger, B; Rinner, B Establishment of clival chordoma cell line MUG-CC1 and lymphoblastoid cells as a model for potential new treatment strategies.
Sci Rep. 2016; 6(7):24195-24195 [OPEN ACCESS]
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Gomez-Escobar, N; Almobadel, N; Alzahrani, O; Feichtinger, J; Planells-Palop, V; Alshehri, Z; Thallinger, GG; Wakeman, JA; McFarlane, RJ Translin and Trax differentially regulate telomere-associated transcript homeostasis.
Oncotarget. 2016; 7(23): 33809-33820. [OPEN ACCESS]
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Harada, Y; Izumi, H; Noguchi, H; Kuma, A; Kawatsu, Y; Kimura, T; Kitada, S; Uramoto, H; Wang, KY; Sasaguri, Y; Hijioka, H; Miyawaki, A; Oya, R; Nakayama, T; Kohno, K; Yamada, S Strong expression of polypeptide N-acetylgalactosaminyltransferase 3 independently predicts shortened disease-free survival in patients with early stage oral squamous cell carcinoma.
Tumour Biol. 2016; 37(1):1357-1368 [OPEN ACCESS]
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Hartmann, L; Dutta, S; Opatz, S; Vosberg, S; Reiter, K; Leubolt, G; Metzeler, KH; Herold, T; Bamopoulos, SA; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Hopfner, KP; Graf, A; Krebs, S; Blum, H; Middeke, JM; Stölzel, F; Thiede, C; Wolf, S; Bohlander, SK; Preiss, C; Chen-Wichmann, L; Wichmann, C; Sauerland, MC; Büchner, T; Berdel, WE; Wörmann, BJ; Braess, J; Hiddemann, W; Spiekermann, K; Greif, PA ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
Nat Commun. 2016; 7:11733-11733 [OPEN ACCESS]
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Hatzl, S; Geiger, O; Kuepper, MK; Caraffini, V; Seime, T; Furlan, T; Nussbaumer, E; Wieser, R; Pichler, M; Scheideler, M; Nowek, K; Jongen-Lavrencic, M; Quehenberger, F; Wölfler, A; Troppmair, J; Sill, H; Zebisch, A Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.
Cancer Res. 2016; 76(12):3644-3654 [OPEN ACCESS]
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He, JC; Yao, W; Wang, JM; Schemmer, P; Yang, Y; Liu, Y; Qian, YW; Qi, WP; Zhang, J; Shen, Q; Yang, T TACC3 overexpression in cholangiocarcinoma correlates with poor prognosis and is a potential anti-cancer molecular drug target for HDAC inhibitors.
Oncotarget. 2016; 7(46):75441-75456 [OPEN ACCESS]
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Jagadeeshan, S; Subramanian, A; Tentu, S; Beesetti, S; Singhal, M; Raghavan, S; Surabhi, RP; Mavuluri, J; Bhoopalan, H; Biswal, J; Pitani, RS; Chidambaram, S; Sundaram, S; Malathi, R; Jeyaraman, J; Nair, AS; Venkatraman, G; Rayala, SK P21-activated kinase 1 (Pak1) signaling influences therapeutic outcome in pancreatic cancer.
Ann Oncol. 2016; 27(8):1546-1556
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Jakobs, A; Uttarkar, S; Schomburg, C; Steinmann, S; Coulibaly, A; Schlenke, P; Berdel, WE; Müller-Tidow, C; Schmidt, TJ; Klempnauer, KH An isoform-specific C/EBPβ inhibitor targets acute myeloid leukemia cells.
Leukemia. 2016; 30(7):1612-1615
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Jeric, I; Maurer, G; Cavallo, AL; Raguz, J; Desideri, E; Tarkowski, B; Parrini, M; Fischer, I; Zatloukal, K; Baccarini, M A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nat Commun. 2016; 7(12):13781-13781 [OPEN ACCESS]
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Kadletz, L; Bigenzahn, J; Thurnher, D; Stanisz, I; Erovic, BM; Schneider, S; Schmid, R; Seemann, R; Birner, P; Heiduschka, G Evaluation of Polo-like kinase 1 as a potential therapeutic target in Merkel cell carcinoma.
Head Neck. 2016; 38 Suppl 1(8):E1918-E1925
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Kargl, J; Andersen, L; Hasenöhrl, C; Feuersinger, D; Stančić, A; Fauland, A; Magnes, C; El-Heliebi, A; Lax, S; Uranitsch, S; Haybaeck, J; Heinemann, A; Schicho, R GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis.
Br J Pharmacol. 2016; 173(1):142-154 [OPEN ACCESS]
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Koyani, CN; Kitz, K; Rossmann, C; Bernhart, E; Huber, E; Trummer, C; Windischhofer, W; Sattler, W; Malle, E Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death.
Biochem Pharmacol. 2016; 104:29-41 [OPEN ACCESS]
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Kumar, AS; Jagadeeshan, S; Subramanian, A; Chidambaram, SB; Surabhi, RP; Singhal, M; Bhoopalan, H; Sekar, S; Pitani, RS; Duvuru, P; Venkatraman, G; Rayala, SK Molecular Mechanism of Regulation of MTA1 Expression by Granulocyte Colony-stimulating Factor.
J Biol Chem. 2016; 291(23):12310-12321 [OPEN ACCESS]
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Leithner, K; Hirschmugl, B; Li, Y; Tang, B; Papp, R; Nagaraj, C; Stacher, E; Stiegler, P; Lindenmann, J; Olschewski, A; Olschewski, H; Hrzenjak, A TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers.
PLoS One. 2016; 11(6):e0157453-e0157453 [OPEN ACCESS]
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