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Publikationen

Suchbegriffe: CARDIOTONIC AGENTS - PHARMACOLOGY , . Treffer: 33

2017

Wallner, M; Khafaga, M; Kolesnik, E; Vafiadis, A; Schwantzer, G; Eaton, DM; Curcic, P; Köstenberger, M; Knez, I; Rainer, PP; Pichler, M; Pieske, B; Lewinski, DV Istaroxime, a potential anticancer drug in prostate cancer, exerts beneficial functional effects in healthy and diseased human myocardium.
Oncotarget. 2017; 8(30):49264-49274 Doi: 10.18632/oncotarget.17540 [OPEN ACCESS]
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Wetzel, J; Pilz, S; Grübler, MR; Fahrleitner-Pammer, A; Dimai, HP; von Lewinski, D; Kolesnik, E; Perl, S; Trummer, C; Schwetz, V; Meinitzer, A; Belyavskiy, E; Völkl, J; Catena, C; Brandenburg, V; März, W; Pieske, B; Brussee, H; Tomaschitz, A; Verheyen, ND Plasma parathyroid hormone and cardiovascular disease in treatment-naive patients with primary hyperparathyroidism: The EPATH trial.
J Clin Hypertens (Greenwich). 2017; 19(11):1173-1180 Doi: 10.1111/jch.13064 [OPEN ACCESS]
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2016

Eisenberg, T; Abdellatif, M; Schroeder, S; Primessnig, U; Stekovic, S; Pendl, T; Harger, A; Schipke, J; Zimmermann, A; Schmidt, A; Tong, M; Ruckenstuhl, C; Dammbrueck, C; Gross, AS; Herbst, V; Magnes, C; Trausinger, G; Narath, S; Meinitzer, A; Hu, Z; Kirsch, A; Eller, K; Carmona-Gutierrez, D; Büttner, S; Pietrocola, F; Knittelfelder, O; Schrepfer, E; Rockenfeller, P; Simonini, C; Rahn, A; Horsch, M; Moreth, K; Beckers, J; Fuchs, H; Gailus-Durner, V; Neff, F; Janik, D; Rathkolb, B; Rozman, J; de Angelis, MH; Moustafa, T; Haemmerle, G; Mayr, M; Willeit, P; von Frieling-Salewsky, M; Pieske, B; Scorrano, L; Pieber, T; Pechlaner, R; Willeit, J; Sigrist, SJ; Linke, WA; Mühlfeld, C; Sadoshima, J; Dengjel, J; Kiechl, S; Kroemer, G; Sedej, S; Madeo, F Cardioprotection and lifespan extension by the natural polyamine spermidine.
Nat Med. 2016; 22(12):1428-1438 Doi: 10.1038/nm.4222 [OPEN ACCESS]
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2015

Wallner, M; Kolesnik, E; Ablasser, K; Khafaga, M; Wakula, P; Ljubojevic, S; Thon-Gutschi, EM; Sourij, H; Kapl, M; Edmunds, NJ; Kuzmiski, JB; Griffith, DA; Knez, I; Pieske, B; von Lewinski, D Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium: GLP-1R mediated effects in human myocardium.
J Mol Cell Cardiol. 2015; 89(Pt B):365-375 Doi: 10.1016/j.yjmcc.2015.09.018
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2013

Schwarzl, M; Seiler, S; Wallner, M; von, Lewinski, D; Huber, S; Maechler, H; Steendijk, P; Zelzer, S; Truschnig-Wilders, M; Obermayer-Pietsch, B; Lueger, A; Pieske, BM; Post, H Mild hypothermia attenuates circulatory and pulmonary dysfunction during experimental endotoxemia.
Crit Care Med. 2013; 41(12):e401-10 Doi: 10.1097/CCM.0b013e31829791da
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Sivakumaran, V; Stanley, BA; Tocchetti, CG; Ballin, JD; Caceres, V; Zhou, L; Keceli, G; Rainer, PP; Lee, DI; Huke, S; Ziolo, MT; Kranias, EG; Toscano, JP; Wilson, GM; O'Rourke, B; Kass, DA; Mahaney, JE; Paolocci, N HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Antioxid Redox Signal. 2013; 19(11):1185-1197 Doi: 10.1089/ars.2012.5057 [OPEN ACCESS]
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Slavic, S; Lauer, D; Sommerfeld, M; Kemnitz, UR; Grzesiak, A; Trappiel, M; Thöne-Reineke, C; Baulmann, J; Paulis, L; Kappert, K; Kintscher, U; Unger, T; Kaschina, E Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome.
J Mol Med (Berl). 2013; 91(7):811-823 Doi: 10.1007/s00109-013-1034-0
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2012

Papp, Z; Édes, I; Fruhwald, S; De Hert, SG; Salmenperä, M; Leppikangas, H; Mebazaa, A; Landoni, G; Grossini, E; Caimmi, P; Morelli, A; Guarracino, F; Schwinger, RH; Meyer, S; Algotsson, L; Wikström, BG; Jörgensen, K; Filippatos, G; Parissis, JT; González, MJ; Parkhomenko, A; Yilmaz, MB; Kivikko, M; Pollesello, P; Follath, F Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan.
Int J Cardiol. 2012; 159(2):82-87 Doi: 10.1016/j.ijcard.2011.07.022 [OPEN ACCESS]
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2011

Yang, LZ; Kockskämper, J; Khan, S; Suarez, J; Walther, S; Doleschal, B; Unterer, G; Khafaga, M; Mächler, H; Heinzel, FR; Dillmann, WH; Pieske, B; Spiess, J cAMP- and Ca²(+) /calmodulin-dependent protein kinases mediate inotropic, lusitropic and arrhythmogenic effects of urocortin 2 in mouse ventricular myocytes.
Br J Pharmacol. 2011; 162(2):544-556 Doi: 10.1111/j.1476-5381.2010.01067.x [OPEN ACCESS]
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2010

von Lewinski, D; Rainer, PP; Gasser, R; Huber, MS; Khafaga, M; Wilhelm, B; Haas, T; Mächler, H; Rössl, U; Pieske, B Glucose-transporter-mediated positive inotropic effects in human myocardium of diabetic and nondiabetic patients.
Metabolism. 2010; 59(7):1020-1028 Doi: 10.1016/j.metabol.2009.10.025
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2007

Toller, W; Knez, I Medical support and surgery of the failing heart: levosimendan.
Scand J Surg. 2007; 96(2):121-124 Doi: 10.1177/145749690709600206 [OPEN ACCESS]
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von Lewinski, D; Bisping, E; Elgner, A; Kockskämper, J; Pieske, B Mechanistic insight into the functional and toxic effects of Strophanthidin in the failing human myocardium.
Eur J Heart Fail. 2007; 9(11):1086-1094 Doi: 10.1016/j.ejheart.2007.08.004 [OPEN ACCESS]
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2006

Dos Santos, RW; Otaviano Campos, F; Neumann Ciuffo, L; Nygren, A; Giles, W; Koch, H ATX-II effects on the apparent location of M cells in a computational model of a human left ventricular wedge.
J Cardiovasc Electrophysiol. 2006; 17 Suppl 1: S86-S95. Doi: 10.1111/j.1540-8167.2006.00389.x
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Toller, WG; Stranz, C Levosimendan, a new inotropic and vasodilator agent.
ANESTHESIOLOGY. 2006; 104(3): 556-569. Doi: 10.1097/00000542-200603000-00024 [OPEN ACCESS]
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2005

von Lewinski, D; Bruns, S; Walther, S; Kögler, H; Pieske, B Insulin causes Ca2+i-dependent and Ca2+i-independent positive inotropic effects in failing human myocardium.
Circulation. 2005; 111(20):2588-2595 Doi: 10.1161/CIRCULATIONAHA.104.497461 [OPEN ACCESS]
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2004

Kockskämper, J; Ahmmed, GU; Zima, AV; Sheehan, KA; Glitsch, HG; Blatter, LA Palytoxin disrupts cardiac excitation-contraction coupling through interactions with P-type ion pumps.
Am J Physiol Cell Physiol. 2004; 287(2):C527-C538 Doi: 10.1152/ajpcell.00541.2003 [OPEN ACCESS]
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2003

Schillinger, W; Ohler, A; Emami, S; Müller, F; Christians, C; Janssen, PM; Kögler, H; Teucher, N; Pieske, B; Seidler, T; Hasenfuss, G The functional effect of adenoviral Na+/Ca2+ exchanger overexpression in rabbit myocytes depends on the activity of the Na+/K+-ATPase.
Cardiovasc Res. 2003; 57(4):996-1003 Doi: 10.1016/S0008-6363(02)00829-5 [OPEN ACCESS]
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von Lewinski, D; Voss, K; Hülsmann, S; Kögler, H; Pieske, B Insulin-like growth factor-1 exerts Ca2+-dependent positive inotropic effects in failing human myocardium.
Circ Res. 2003; 92(2):169-176 Doi: 10.1161/01.RES.0000051885.70159.12 [OPEN ACCESS]
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2002

Podesser, BK; Schirnhofer, J; Bernecker, OY; Kröner, A; Franz, M; Semsroth, S; Fellner, B; Neumüller, J; Hallström, S; Wolner, E Optimizing ischemia/reperfusion in the failing rat heart--improved myocardial protection with acute ACE inhibition.
CIRCULATION 2002 106: I277-I283. Doi: 10.1161/01.cir.0000032903.33237.40 [OPEN ACCESS]
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2001

Baudet, S; Weisser, J; Janssen, AP; Beulich, K; Bieligk, U; Pieske, B; Noireaud, J; Janssen, PM; Hasenfuss, G; Prestle, J Increased basal contractility of cardiomyocytes overexpressing protein kinase C epsilon and blunted positive inotropic response to endothelin-1.
Cardiovasc Res. 2001; 50(3):486-494 Doi: 10.1016/S0008-6363(01)00225-5 [OPEN ACCESS]
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Ver Heyen, M; Heymans, S; Antoons, G; Reed, T; Periasamy, M; Awede, B; Lebacq, J; Vangheluwe, P; Dewerchin, M; Collen, D; Sipido, K; Carmeliet, P; Wuytack, F Replacement of the muscle-specific sarcoplasmic reticulum Ca(2+)-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart.
Circ Res. 2001; 89(9):838-846 Doi: 10.1161/hh2101.098466 [OPEN ACCESS]
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2000

Maier, LS; Schwan, C; Schillinger, W; Minami, K; Schütt, U; Pieske, B Gingerol, isoproterenol and ouabain normalize impaired post-rest behavior but not force-frequency relation in failing human myocardium.
Cardiovasc Res. 2000; 45(4):913-924 Doi: 10.1016/S0008-6363(99)00387-9 [OPEN ACCESS]
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1999

Köppel, H; Holzmann, S; Pilger, E; Klein, W; Gasser, R Minimal effects of levosimendan on coronary artery smooth muscle tone.
CARDIOVASC DRUG THER 1999 13: 357-358. Doi: 10.1023%2FA%3A1007719818929
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1998

Hasenfuss, G; Pieske, B; Castell, M; Kretschmann, B; Maier, LS; Just, H Influence of the novel inotropic agent levosimendan on isometric tension and calcium cycling in failing human myocardium.
Circulation. 1998; 98(20):2141-2147 Doi: 10.1161/01.CIR.98.20.2141 [OPEN ACCESS]
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Holubarsch, C; Lüdemann, J; Wiessner, S; Ruf, T; Schulte-Baukloh, H; Schmidt-Schweda, S; Pieske, B; Posival, H; Just, H Shortening versus isometric contractions in isolated human failing and non-failing left ventricular myocardium: dependency of external work and force on muscle length, heart rate and inotropic stimulation.
Cardiovasc Res. 1998; 37(1):46-57 Doi: 10.1016/S0008-6363(97)00215-0 [OPEN ACCESS]
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Pieske, B; Trost, S; Schutt, K; Minami, K; Just, H; Hasenfuss, G Influence of Forskolin on the force-frequency behavior in nonfailing and end-stage failing human myocardium
BASIC RES CARDIOL. 1998; 93: 66-75. Doi: 10.1007/s003950050222
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Takigawa, T; Alzheimer, C; Quasthoff, S; Grafe, P A special blocker reveals the presence and function of the hyperpolarization-activated cation current IH in peripheral mammalian nerve fibres.
Neuroscience. 1998; 82(3):631-634 Doi: 10.1016/S0306-4522(97)00383-7
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1996

Herzig, JW; Chiesi, M; Depersin, H; Grüninger, S; Hasenfuss, G; Kubalek, R; Leutert, T; Pieske, B; Pioch, K; Wenk, P; Holubarsch, C Ca2+ sensitization in idiopathic dilated human myocardium. Differential in vitro effects of (+)-(5-methyl-6-phenyl)-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazoci ne-2,4-dione, a novel purely Ca2+sensitizing agent, and (+)-5-(1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinolin-6-yl)-6-meth yl-3, 6-dihydro-2H-1,3,4-thiadiazin-2-one on skinned fibres and isolated ventricular strips.
Arzneimittelforschung. 1996; 46(6):586-593
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1995

Hasenfuss, G; Pieske, B; Kretschmann, B; Holubarsch, C; Alpert, NR; Just, H Effects of calcium sensitizers on intracellular calcium handling and myocardial energetics.
J Cardiovasc Pharmacol. 1995; 26 Suppl 1(4): S45-S51. Doi: 10.1097/00005344-199506261-00006
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1990

Böhm, M; Gierschik, P; Jakobs, KH; Pieske, B; Schnabel, P; Ungerer, M; Erdmann, E Increase of Gi alpha in human hearts with dilated but not ischemic cardiomyopathy.
Circulation. 1990; 82(4):1249-1265 Doi: 10.1161/01.CIR.82.4.1249 [OPEN ACCESS]
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1989

Böhm, M; Diet, F; Pieske, B; Erdmann, E Screening of positive inotropic agents in isolated cardiac preparations from different sources.
J Pharmacol Methods. 1989; 21(1):33-44 Doi: 10.1016/0160-5402(89)90020-X
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Schreibmayer, W; Tritthart, HA; Schindler, H The cardiac sodium channel shows a regular substate pattern indicating synchronized activity of several ion pathways instead of one.
Biochim Biophys Acta. 1989; 986(1):172-186 Doi: 10.1016/0005-2736(89)90288-5
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1988

Näbauer, M; Böhm, M; Brown, L; Diet, F; Eichhorn, M; Kemkes, B; Pieske, B; Erdmann, E Positive inotropic effects in isolated ventricular myocardium from non-failing and terminally failing human hearts.
Eur J Clin Invest. 1988; 18(6):600-606 Doi: 10.1111/j.1365-2362.1988.tb01274.x
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