Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: CARDIAC HYPERTROPHY, . Treffer: 45

2023

Messerer, J; Wrede, C; Schipke, J; Brandenberger, C; Abdellatif, M; Eisenberg, T; Madeo, F; Sedej, S; Mühlfeld, C Spermidine supplementation influences mitochondrial number and morphology in the heart of aged mice.
J Anat. 2023; 242(1):91-101 Doi: 10.1111/joa.13618 [OPEN ACCESS]
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2022

Abdellatif, M; Madeo, F; Kroemer, G; Sedej, S Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.
Autophagy. 2022; 18(10):2500-2502 Doi: 10.1080/15548627.2022.2095835 [OPEN ACCESS]
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Ljubojević-Holzer, S; Kraler, S; Djalinac, N; Abdellatif, M; Voglhuber, J; Schipke, J; Schmidt, M; Kling, KM; Franke, GT; Herbst, V; Zirlik, A; von, Lewinski, D; Scherr, D; Rainer, PP; Kohlhaas, M; Nickel, A; Mühlfeld, C; Maack, C; Sedej, S Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.
Cardiovasc Res. 2022; 118(6):1492-1505 Doi: 10.1093/cvr/cvab112 [OPEN ACCESS]
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2021

Del, Gaudio, I; Rubinelli, L; Sasset, L; Wadsack, C; Hla, T; Di, Lorenzo, A Endothelial Spns2 and ApoM Regulation of Vascular Tone and Hypertension Via Sphingosine-1-Phosphate.
J Am Heart Assoc. 2021; 10(14): e021261 Doi: 10.1161/JAHA.121.021261 [OPEN ACCESS]
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Gross, P; Johnson, J; Romero, CM; Eaton, DM; Poulet, C; Sanchez-Alonso, J; Lucarelli, C; Ross, J; Gibb, AA; Garbincius, JF; Lambert, J; Varol, E; Yang, Y; Wallner, M; Feldsott, EA; Kubo, H; Berretta, RM; Yu, D; Rizzo, V; Elrod, J; Sabri, A; Gorelik, J; Chen, X; Houser, SR Interaction of the Joining Region in Junctophilin-2 With the L-Type Ca2+ Channel Is Pivotal for Cardiac Dyad Assembly and Intracellular Ca2+ Dynamics.
Circ Res. 2021; 128(1):92-114 Doi: 10.1161/CIRCRESAHA.119.315715 [OPEN ACCESS]
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Helmstadter, KG; Ljubojevic-Holzer, S; Wood, BM; Taheri, KD; Sedej, S; Erickson, JR; Bossuyt, J; Bers, DM CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes.
Basic Res Cardiol. 2021; 116(1):11-11 Doi: 10.1007/s00395-021-00850-2 [OPEN ACCESS]
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2019

Gollmer, J; Zirlik, A; Bugger, H Established and Emerging Mechanisms of Diabetic Cardiomyopathy.
J Lipid Atheroscler. 2019; 8(1):26-47 Doi: 10.12997/jla.2019.8.1.26 [OPEN ACCESS]
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2018

Diehl, P; Gaul, DS; Sogl, J; Flierl, U; Henstridge, D; Pahla, J; Bugger, H; Emmert, MY; Ruschitzka, F; Bode, C; Lüscher, TF; Moser, M; Matter, CM; Peter, K; Winnik, S The effect of oxygen in Sirt3-mediated myocardial protection: a proof-of-concept study in cultured cardiomyoblasts.
J Thromb Thrombolysis. 2018; 46(1): 102-112. Doi: 10.1007/s11239-018-1677-3
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Harper, SC; Johnson, J; Borghetti, G; Zhao, H; Wang, T; Wallner, M; Kubo, H; Feldsott, EA; Yang, Y; Joo, Y; Gou, X; Sabri, AK; Gupta, P; Myzithras, M; Khalil, A; Franti, M; Houser, SR GDF11 Decreases Pressure Overload-Induced Hypertrophy, but Can Cause Severe Cachexia and Premature Death.
Circ Res. 2018; 123(11):1220-1231 Doi: 10.1161/CIRCRESAHA.118.312955 [OPEN ACCESS]
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2017

Troupes, CD; Wallner, M; Borghetti, G; Zhang, C; Mohsin, S; von Lewinski, D; Berretta, RM; Kubo, H; Chen, X; Soboloff, J; Houser, S Role of STIM1 (Stromal Interaction Molecule 1) in Hypertrophy-Related Contractile Dysfunction.
Circ Res. 2017; 121(2):125-136 Doi: 10.1161/CIRCRESAHA.117.311094 [OPEN ACCESS]
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2016

Bugger, H; Witt, CN; Bode, C Mitochondrial sirtuins in the heart.
Heart Fail Rev. 2016; 21(5): 519-528. Doi: 10.1007/s10741-016-9570-7
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Eisenberg, T; Abdellatif, M; Schroeder, S; Primessnig, U; Stekovic, S; Pendl, T; Harger, A; Schipke, J; Zimmermann, A; Schmidt, A; Tong, M; Ruckenstuhl, C; Dammbrueck, C; Gross, AS; Herbst, V; Magnes, C; Trausinger, G; Narath, S; Meinitzer, A; Hu, Z; Kirsch, A; Eller, K; Carmona-Gutierrez, D; Büttner, S; Pietrocola, F; Knittelfelder, O; Schrepfer, E; Rockenfeller, P; Simonini, C; Rahn, A; Horsch, M; Moreth, K; Beckers, J; Fuchs, H; Gailus-Durner, V; Neff, F; Janik, D; Rathkolb, B; Rozman, J; de Angelis, MH; Moustafa, T; Haemmerle, G; Mayr, M; Willeit, P; von Frieling-Salewsky, M; Pieske, B; Scorrano, L; Pieber, T; Pechlaner, R; Willeit, J; Sigrist, SJ; Linke, WA; Mühlfeld, C; Sadoshima, J; Dengjel, J; Kiechl, S; Kroemer, G; Sedej, S; Madeo, F Cardioprotection and lifespan extension by the natural polyamine spermidine.
Nat Med. 2016; 22(12):1428-1438 Doi: 10.1038/nm.4222 [OPEN ACCESS]
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Kirschmer, N; Bandleon, S; von Ehrlich-Treuenstätt, V; Hartmann, S; Schaaf, A; Lamprecht, AK; Miranda-Laferte, E; Langsenlehner, T; Ritter, O; Eder, P TRPC4α and TRPC4β Similarly Affect Neonatal Cardiomyocyte Survival during Chronic GPCR Stimulation.
PLoS One. 2016; 11(12):e0168446-e0168446 Doi: 10.1371/journal.pone.0168446 [OPEN ACCESS]
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Koentges, C; Bode, C; Bugger, H SIRT3 in Cardiac Physiology and Disease.
Front Cardiovasc Med. 2016; 3(1):38-38 Doi: 10.3389/fcvm.2016.00038 [OPEN ACCESS]
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Kooij, V; Viswanathan, MC; Lee, DI; Rainer, PP; Schmidt, W; Kronert, WA; Harding, SE; Kass, DA; Bernstein, SI; Van Eyk, JE; Cammarato, A Profilin modulates sarcomeric organization and mediates cardiomyocyte hypertrophy.
Cardiovasc Res. 2016; 110(2):238-248 Doi: 10.1093/cvr/cvw050 [OPEN ACCESS]
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2015

Braun, M; Hettinger, N; Koentges, C; Pfeil, K; Cimolai, MC; Hoffmann, MM; Osterholt, M; Doenst, T; Bode, C; Bugger, H Myocardial mitochondrial and contractile function are preserved in mice lacking adiponectin.
PLoS One. 2015; 10(3): e0119416-e0119416. Doi: 10.1371/journal.pone.0119416 [OPEN ACCESS]
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Koentges, C; Pfeil, K; Schnick, T; Wiese, S; Dahlbock, R; Cimolai, MC; Meyer-Steenbuck, M; Cenkerova, K; Hoffmann, MM; Jaeger, C; Odening, KE; Kammerer, B; Hein, L; Bode, C; Bugger, H SIRT3 deficiency impairs mitochondrial and contractile function in the heart.
Basic Res Cardiol. 2015; 110(4): 36-36. Doi: 10.1007/s00395-015-0493-6
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Ljubojevic, S; Bers, DM Nuclear calcium in cardiac myocytes.
J Cardiovasc Pharmacol. 2015; 65(3):211-217 Doi: 10.1097/FJC.0000000000000174 [OPEN ACCESS]
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Mayer, SC; Gilsbach, R; Preissl, S; Monroy Ordonez, EB; Schnick, T; Beetz, N; Lother, A; Rommel, C; Ihle, H; Bugger, H; Rühle, F; Schrepper, A; Schwarzer, M; Heilmann, C; Bönisch, U; Gupta, SK; Wilpert, J; Kretz, O; von Elverfeldt, D; Orth, J; Aktories, K; Beyersdorf, F; Bode, C; Stiller, B; Krüger, M; Thum, T; Doenst, T; Stoll, M; Hein, L Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure.
Circ Res. 2015; 117(7): 622-633. Doi: 10.1161/CIRCRESAHA.115.306721 [OPEN ACCESS]
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Wende, AR; O'Neill, BT; Bugger, H; Riehle, C; Tuinei, J; Buchanan, J; Tsushima, K; Wang, L; Caro, P; Guo, A; Sloan, C; Kim, BJ; Wang, X; Pereira, RO; McCrory, MA; Nye, BG; Benavides, GA; Darley-Usmar, VM; Shioi, T; Weimer, BC; Abel, ED Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.
Mol Cell Biol. 2015; 35(5): 831-846. Doi: 10.1128/MCB.01109-14 [OPEN ACCESS]
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2014

Bisping, E; Wakula, P; Poteser, M; Heinzel, FR Targeting cardiac hypertrophy: toward a causal heart failure therapy.
J Cardiovasc Pharmacol. 2014; 64(4):293-305 Doi: 10.1097/FJC.0000000000000126 [OPEN ACCESS]
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2012

Bisping, E; Ikeda, S; Sedej, M; Wakula, P; McMullen, JR; Tarnavski, O; Sedej, S; Izumo, S; Pu, WT; Pieske, B Transcription factor GATA4 is activated but not required for insulin-like growth factor 1 (IGF1)-induced cardiac hypertrophy.
J Biol Chem. 2012; 287(13):9827-9834 Doi: 10.1074/jbc.M111.338749 [OPEN ACCESS]
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Goonasekera, SA; Hammer, K; Auger-Messier, M; Bodi, I; Chen, X; Zhang, H; Reiken, S; Elrod, JW; Correll, RN; York, AJ; Sargent, MA; Hofmann, F; Moosmang, S; Marks, AR; Houser, SR; Bers, DM; Molkentin, JD Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice.
J Clin Invest. 2012; 122(1):280-290 Doi: 10.1172/JCI58227 [OPEN ACCESS]
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Larson, JE; Rainer, PP; Watts, VL; Yang, R; Miller, KL; Phan, A; Barouch, LA Dependence of β3-adrenergic signaling on the adipokine leptin in cardiac myocytes.
Int J Obes (Lond). 2012; 36(6):876-879 Doi: 10.1038/ijo.2011.137 [OPEN ACCESS]
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2011

Klaiber, M; Dankworth, B; Kruse, M; Hartmann, M; Nikolaev, VO; Yang, RB; Völker, K; Gassner, B; Oberwinkler, H; Feil, R; Freichel, M; Groschner, K; Skryabin, BV; Frantz, S; Birnbaumer, L; Pongs, O; Kuhn, M A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide.
Proc Natl Acad Sci U S A. 2011; 108(45):18500-18505 Doi: 10.1073/pnas.1103300108 [OPEN ACCESS]
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Riehle, C; Wende, AR; Zaha, VG; Pires, KM; Wayment, B; Olsen, C; Bugger, H; Buchanan, J; Wang, X; Moreira, AB; Doenst, T; Medina-Gomez, G; Litwin, SE; Lelliott, CJ; Vidal-Puig, A; Abel, ED PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy.
Circ Res. 2011; 109(7): 783-793. Doi: 10.1161/CIRCRESAHA.111.243964 [OPEN ACCESS]
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2010

Rohini, A; Agrawal, N; Koyani, CN; Singh, R Molecular targets and regulators of cardiac hypertrophy.
Pharmacol Res. 2010; 61(4):269-280 Doi: 10.1016/j.phrs.2009.11.012
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2008

Bito, V; Heinzel, FR; Biesmans, L; Antoons, G; Sipido, KR Crosstalk between L-type Ca2+ channels and the sarcoplasmic reticulum: alterations during cardiac remodelling.
Cardiovasc Res. 2008; 77(2): 315-324. Doi: 10.1093/cvr/cvm063 [OPEN ACCESS]
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Jacobshagen, C; Grüber, M; Teucher, N; Schmidt, AG; Unsöld, BW; Toischer, K; Nguyen, VP; Maier, LS; Kögler, H; Hasenfuss, G Celecoxib modulates hypertrophic signalling and prevents load-induced cardiac dysfunction.
Eur J Heart Fail. 2008; 10(4): 334-342. Doi: 10.1016/j.ejheart.2008.02.013 [OPEN ACCESS]
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2007

Antoons, G; Volders, PG; Stankovicova, T; Bito, V; Stengl, M; Vos, MA; Sipido, KR Window Ca2+ current and its modulation by Ca2+ release in hypertrophied cardiac myocytes from dogs with chronic atrioventricular block.
J Physiol. 2007; 579(Pt 1):147-160 Doi: 10.1113/jphysiol.2006.124222 [OPEN ACCESS]
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Sipido, KR; Bito, V; Antoons, G; Volders, PG; Vos, MA Na/Ca exchange and cardiac ventricular arrhythmias.
Ann N Y Acad Sci. 2007; 1099(6 Suppl):339-348 Doi: 10.1196/annals.1387.066
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2006

Bisping, E; Ikeda, S; Kong, SW; Tarnavski, O; Bodyak, N; McMullen, JR; Rajagopal, S; Son, JK; Ma, Q; Springer, Z; Kang, PM; Izumo, S; Pu, WT Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure.
Proc Natl Acad Sci U S A. 2006; 103(39):14471-14476 Doi: 10.1073/pnas.0602543103 [OPEN ACCESS]
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2004

McMullen, JR; Shioi, T; Huang, WY; Zhang, L; Tarnavski, O; Bisping, E; Schinke, M; Kong, S; Sherwood, MC; Brown, J; Riggi, L; Kang, PM; Izumo, S The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway.
J Biol Chem. 2004; 279(6):4782-4793 Doi: 10.1074/jbc.M310405200 [OPEN ACCESS]
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2003

Dash, R; Schmidt, AG; Pathak, A; Gerst, MJ; Biniakiewicz, D; Kadambi, VJ; Hoit, BD; Abraham, WT; Kranias, EG Differential regulation of p38 mitogen-activated protein kinase mediates gender-dependent catecholamine-induced hypertrophy.
Cardiovasc Res. 2003; 57(3): 704-714. Doi: 10.1016/S0008-6363(02)00772-1 [OPEN ACCESS]
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Gattenlohner, S; Waller, C; Ertl, G; Bultmann, BD; Muller-Hermelink, HK; Marx, A NCAM(CD56) and RUNX1(AML1) are up-regulated in human ischemic cardiomyopathy and a rat model of chronic cardiac ischemia.
Am J Pathol. 2003; 163(3):1081-1090 Doi: 10.1016/S0002-9440(10)63467-0 [OPEN ACCESS]
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Lorenz, M; Hauser, AC; Püspök-Schwarz, M; Kotanko, P; Arias, I; Zodl, H; Kramar, R; Paschke, E; Voigtländer, T; Sunder-Plassmann, G Anderson-Fabry disease in Austria.
Wien Klin Wochenschr. 2003; 115(7-8):235-240 Doi: 10.1007/BF03040321 (- Case Report)
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Sato, Y; Schmidt, AG; Kiriazis, H; Hoit, BD; Kranias, EG Compensated hypertrophy of cardiac ventricles in aged transgenic FVB/N mice overexpressing calsequestrin.
Mol Cell Biochem. 2003; 242(1-2): 19-25. Doi: 10.1023/A:1021196402952
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Song, Q; Schmidt, AG; Hahn, HS; Carr, AN; Frank, B; Pater, L; Gerst, M; Young, K; Hoit, BD; McConnell, BK; Haghighi, K; Seidman, CE; Seidman, JG; Dorn, GW; Kranias, EG Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.
J Clin Invest. 2003; 111(6): 859-867. Doi: 10.1172/JCI16738 [OPEN ACCESS]
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2002

Fiedler, B; Lohmann, SM; Smolenski, A; Linnemuller, S; Pieske, B; Schroder, F; Molkentin, JD; Drexler, H; Wollert, KC Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes.
Proc Natl Acad Sci U S A. 2002; 99(17):11363-11368 Doi: 10.1073/pnas.162100799 [OPEN ACCESS]
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2001

Sato, Y; Kiriazis, H; Yatani, A; Schmidt, AG; Hahn, H; Ferguson, DG; Sako, H; Mitarai, S; Honda, R; Mesnard-Rouiller, L; Frank, KF; Beyermann, B; Wu, G; Fujimori, K; Dorn, GW; Kranias, EG Rescue of contractile parameters and myocyte hypertrophy in calsequestrin overexpressing myocardium by phospholamban ablation.
J Biol Chem. 2001; 276(12): 9392-9399. Doi: 10.1074/jbc.M006889200 [OPEN ACCESS]
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Ver Heyen, M; Heymans, S; Antoons, G; Reed, T; Periasamy, M; Awede, B; Lebacq, J; Vangheluwe, P; Dewerchin, M; Collen, D; Sipido, K; Carmeliet, P; Wuytack, F Replacement of the muscle-specific sarcoplasmic reticulum Ca(2+)-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart.
Circ Res. 2001; 89(9):838-846 Doi: 10.1161/hh2101.098466 [OPEN ACCESS]
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2000

Brittsan, AG; Carr, AN; Schmidt, AG; Kranias, EG Maximal inhibition of SERCA2 Ca(2+) affinity by phospholamban in transgenic hearts overexpressing a non-phosphorylatable form of phospholamban.
J Biol Chem. 2000; 275(16): 12129-12135. Doi: 10.1074/jbc.275.16.12129 [OPEN ACCESS]
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Janssen, PM; Zeitz, O; Keweloh, B; Siegel, U; Maier, LS; Barckhausen, P; Pieske, B; Prestle, J; Lehnart, SE; Hasenfuss, G Influence of cyclosporine A on contractile function, calcium handling, and energetics in isolated human and rabbit myocardium.
Cardiovasc Res. 2000; 47(1):99-107 Doi: 10.1016/S0008-6363(00)00052-3 [OPEN ACCESS]
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Zvaritch, E; Backx, PH; Jirik, F; Kimura, Y; de Leon, S; Schmidt, AG; Hoit, BD; Lester, JW; Kranias, EG; MacLennan, DH The transgenic expression of highly inhibitory monomeric forms of phospholamban in mouse heart impairs cardiac contractility.
J Biol Chem. 2000; 275(20): 14985-14991. Doi: 10.1074/jbc.275.20.14985 [OPEN ACCESS]
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1990

Gasser, R Calcium antagonists: pharmacologic agents in search of new clinical indications.
ANGIOLOGY. 1990; 41(1): 36-43. Doi: 10.1177/000331979004100106
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