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Publikationen

Suchbegriffe: CALCIUM SIGNALING - DRUG EFFECTS , . Treffer: 47

2021

Cellini, A; Höfler, D; Arias-Loza, PA; Bandleon, S; Langsenlehner, T; Kohlhaas, M; Maack, C; Bauer, WR; Eder-Negrin, P The α2-isoform of the Na⁺/K⁺-ATPase protects against pathological remodeling and β-adrenergic desensitization after myocardial infarction.
Am J Physiol Heart Circ Physiol. 2021; 321(4):H650-H662 Doi: 10.1152/ajpheart.00808.2020
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2018

Mhatre, KN; Wakula, P; Klein, O; Bisping, E; Völkl, J; Pieske, B; Heinzel, FR Crosstalk between FGF23- and angiotensin II-mediated Ca²⁺ signaling in pathological cardiac hypertrophy.
Cell Mol Life Sci. 2018; 75(23):4403-4416 Doi: 10.1007/s00018-018-2885-x
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2017

Bondarenko, AI; Montecucco, F; Panasiuk, O; Sagach, V; Sidoryak, N; Brandt, KJ; Mach, F GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na⁺-Ca²⁺ exchanger and endoplasmic reticulum Ca²⁺ refilling.
Vascul Pharmacol. 2017; 89(2):39-48 Doi: 10.1016/j.vph.2017.01.002 [OPEN ACCESS]
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2016

Leis, HJ; Windischhofer, W Potentiation of endothelin-1-induced prostaglandin E2 formation by Ni(2+) and Sr(2+) in murine osteoblastic MC3T3-E1 cells.
J Trace Elem Med Biol. 2016; 33(3):81-86 Doi: 10.1016/j.jtemb.2015.10.001
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Pelzmann, B; Di Giuro, CM; Zorn-Pauly, K; Rossmann, C; Hallström, S; Groschner, K; Fameli, N Functional impairment of endothelial cells by the antimycotic amphotericin B.
Biochem Biophys Res Commun. 2016; 472(1):40-45 Doi: 10.1016/j.bbrc.2016.02.054
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Tiapko, O; Bacsa, B; de la Cruz, GG; Glasnov, T; Groschner, K Optopharmacological control of TRPC channels by coumarin-caged lipids is associated with a phototoxic membrane effect.
Sci China Life Sci. 2016; 59(8):802-810 Doi: 10.1007/s11427-016-5095-5 [OPEN ACCESS]
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2015

Hammer, KP; Ljubojevic, S; Ripplinger, CM; Pieske, BM; Bers, DM Cardiac myocyte alternans in intact heart: Influence of cell-cell coupling and β-adrenergic stimulation.
J Mol Cell Cardiol. 2015; 84(2):1-9 Doi: 10.1016/j.yjmcc.2015.03.012 [OPEN ACCESS]
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2014

Navarro-Dorado, J; Garcia-Alonso, M; van Breemen, C; Tejerina, T; Fameli, N Calcium oscillations in human mesenteric vascular smooth muscle.
Biochem Biophys Res Commun. 2014; 445(1): 84-88. Doi: 10.1016/j.bbrc.2014.01.150 [OPEN ACCESS]
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2013

Bondarenko, AI; Drachuk, K; Panasiuk, O; Sagach, V; Deak, AT; Malli, R; Graier, WF N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs.
Br J Pharmacol. 2013; 169(4):933-948 Doi: 10.1111/bph.12180 [OPEN ACCESS]
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Derler, I; Schindl, R; Fritsch, R; Heftberger, P; Riedl, MC; Begg, M; House, D; Romanin, C The action of selective CRAC channel blockers is affected by the Orai pore geometry.
Cell Calcium. 2013; 53(2): 139-151. Doi: 10.1016/j.ceca.2012.11.005 [OPEN ACCESS]
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González-Cobos, JC; Zhang, X; Zhang, W; Ruhle, B; Motiani, RK; Schindl, R; Muik, M; Spinelli, AM; Bisaillon, JM; Shinde, AV; Fahrner, M; Singer, HA; Matrougui, K; Barroso, M; Romanin, C; Trebak, M Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia.
Circ Res. 2013; 112(7): 1013-1025. Doi: 10.1161/CIRCRESAHA.111.300220 [OPEN ACCESS]
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Hohendanner, F; Ljubojević, S; MacQuaide, N; Sacherer, M; Sedej, S; Biesmans, L; Wakula, P; Platzer, D; Sokolow, S; Herchuelz, A; Antoons, G; Sipido, K; Pieske, B; Heinzel, FR Intracellular dyssynchrony of diastolic cytosolic [Ca²⁺] decay in ventricular cardiomyocytes in cardiac remodeling and human heart failure.
Circ Res. 2013; 113(5):527-538 Doi: 10.1161/CIRCRESAHA.113.300895 [OPEN ACCESS]
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Kargl, J; Brown, AJ; Andersen, L; Dorn, G; Schicho, R; Waldhoer, M; Heinemann, A A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function.
J Pharmacol Exp Ther. 2013; 346(1):54-66 Doi: 10.1124/jpet.113.204180 [OPEN ACCESS]
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Koenig, S; Schernthaner, M; Maechler, H; Kappe, CO; Glasnov, TN; Hoefler, G; Braune, M; Wittchow, E; Groschner, K A TRPC3 blocker, ethyl-1-(4-(2,3,3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (Pyr3), prevents stent-induced arterial remodeling.
J Pharmacol Exp Ther. 2013; 344(1):33-40 Doi: 10.1124/jpet.112.196832 [OPEN ACCESS]
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König, S; Browne, S; Doleschal, B; Schernthaner, M; Poteser, M; Mächler, H; Wittchow, E; Braune, M; Muik, M; Romanin, C; Groschner, K Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle.
Am J Physiol Heart Circ Physiol. 2013; 305(11):H1646-H1657 Doi: 10.1152/ajpheart.00365.2013 [OPEN ACCESS]
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Lichtenegger, M; Stockner, T; Poteser, M; Schleifer, H; Platzer, D; Romanin, C; Groschner, K A novel homology model of TRPC3 reveals allosteric coupling between gate and selectivity filter.
Cell Calcium. 2013; 54(3):175-185 Doi: 10.1016/j.ceca.2013.05.010 [OPEN ACCESS]
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Sivakumaran, V; Stanley, BA; Tocchetti, CG; Ballin, JD; Caceres, V; Zhou, L; Keceli, G; Rainer, PP; Lee, DI; Huke, S; Ziolo, MT; Kranias, EG; Toscano, JP; Wilson, GM; O'Rourke, B; Kass, DA; Mahaney, JE; Paolocci, N HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Antioxid Redox Signal. 2013; 19(11):1185-1197 Doi: 10.1089/ars.2012.5057 [OPEN ACCESS]
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2012

Willer, EA; Malli, R; Bondarenko, AI; Zahler, S; Vollmar, AM; Graier, WF; Fürst, R The vascular barrier-protecting hawthorn extract WS® 1442 raises endothelial calcium levels by inhibition of SERCA and activation of the IP3 pathway.
J Mol Cell Cardiol. 2012; 53(4):567-577 Doi: 10.1016/j.yjmcc.2012.07.002
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2011

Biesmans, L; Macquaide, N; Heinzel, FR; Bito, V; Smith, GL; Sipido, KR Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density.
PLoS One. 2011; 6(10):e25100-e25100 Doi: 10.1371/journal.pone.0025100 [OPEN ACCESS]
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Ljubojević, S; Walther, S; Asgarzoei, M; Sedej, S; Pieske, B; Kockskämper, J In situ calibration of nucleoplasmic versus cytoplasmic Ca²+ concentration in adult cardiomyocytes.
Biophys J. 2011; 100(10):2356-2366 Doi: 10.1016/j.bpj.2011.03.060 [OPEN ACCESS]
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2010

Bondarenko, A; Waldeck-Weiermair, M; Naghdi, S; Poteser, M; Malli, R; Graier, WF GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells.
Br J Pharmacol. 2010; 161(2): 308-320. Doi: 10.1111/j.1476-5381.2010.00744.x [OPEN ACCESS]
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Oros, A; Houtman, MJ; Neco, P; Gomez, AM; Rajamani, S; Oosterhoff, P; Attevelt, NJ; Beekman, JD; van der Heyden, MA; Ver Donck, L; Belardinelli, L; Richard, S; Antoons, G; Vos, MA; CONTICA investigators Robust anti-arrhythmic efficacy of verapamil and flunarizine against dofetilide-induced TdP arrhythmias is based upon a shared and a different mode of action.
Br J Pharmacol. 2010; 161(1):162-175 Doi: 10.1111/j.1476-5381.2010.00883.x [OPEN ACCESS]
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2009

Antoons, G; Sipido, KR Dofetilide as activator of Na/Ca exchange: new perspectives on an 'old' drug. Editorial to: "Dofetilide enhances the contractility of rat ventricular myocytes via augmentation of Na+-Ca 2+ exchange" by Xuan-Ping Zhang et al.
Cardiovasc Drugs Ther. 2009; 23(3): 189-192. Doi: 10.1007/s10557-009-6170-y [OPEN ACCESS]
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Gemes, G; Rigaud, M; Weyker, PD; Abram, SE; Weihrauch, D; Poroli, M; Zoga, V; Hogan, QH Depletion of calcium stores in injured sensory neurons: anatomic and functional correlates.
Anesthesiology. 2009; 111(2): 393-405. Doi: 10.1097/ALN.0b013e3181ae63b0 [OPEN ACCESS]
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2008

Waldeck-Weiermair, M; Zoratti, C; Osibow, K; Balenga, N; Goessnitzer, E; Waldhoer, M; Malli, R; Graier, WF Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression.
J Cell Sci. 2008; 121(Pt 10): 1704-1717. Doi: 10.1242/jcs.020958 [OPEN ACCESS]
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2007

Fian, R; Grasser, E; Treiber, F; Schmidt, R; Niederl, P; Rosker, C The contribution of TRPV4-mediated calcium signaling to calcium homeostasis in endothelial cells.
J Recept Signal Transduct Res. 2007; 27(2-3):113-124 Doi: 10.1080/10799890701402446
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Fuchs, A; Rigaud, M; Sarantopoulos, CD; Filip, P; Hogan, QH Contribution of calcium channel subtypes to the intracellular calcium signal in sensory neurons: the effect of injury.
Anesthesiology. 2007; 107(1):117-127 Doi: 10.1097/01.anes.0000267511.21864.93 [OPEN ACCESS]
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Malli, R; Frieden, M; Hunkova, M; Trenker, M; Graier, WF Ca2+ refilling of the endoplasmic reticulum is largely preserved albeit reduced Ca2+ entry in endothelial cells.
Cell Calcium. 2007; 41(1): 63-76. Doi: 10.1016/j.ceca.2006.05.001 [OPEN ACCESS]
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Sarantopoulos, CD; McCallum, JB; Rigaud, M; Fuchs, A; Kwok, WM; Hogan, QH Opposing effects of spinal nerve ligation on calcium-activated potassium currents in axotomized and adjacent mammalian primary afferent neurons.
Brain Res. 2007; 1132(1): 84-99. Doi: 10.1016/j.brainres.2006.11.055 [OPEN ACCESS]
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Schillinger, W; Teucher, N; Sossalla, S; Kettlewell, S; Werner, C; Raddatz, D; Elgner, A; Tenderich, G; Pieske, B; Ramadori, G; Schöndube, FA; Kögler, H; Kockskämper, J; Maier, LS; Schwörer, H; Smith, GL; Hasenfuss, G Negative inotropy of the gastric proton pump inhibitor pantoprazole in myocardium from humans and rabbits: evaluation of mechanisms.
Circulation. 2007; 116(1):57-66 Doi: 10.1161/CIRCULATIONAHA.106.666008 [OPEN ACCESS]
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Wiesenberger, G; Steinleitner, K; Malli, R; Graier, WF; Vormann, J; Schweyen, RJ; Stadler, JA Mg2+ deprivation elicits rapid Ca2+ uptake and activates Ca2+/calcineurin signaling in Saccharomyces cerevisiae.
Eukaryot Cell. 2007; 6(4): 592-599. Doi: 10.1128/EC.00382-06 [OPEN ACCESS]
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2006

Jost, B; Grabert, J; Patz, S; Schmidt, M; Wahle, P GABAC receptor subunit mRNA expression in the rat superior colliculus is regulated by calcium channels, neurotrophins, and GABAC receptor activity.
Brain Cell Biol. 2006; 35(4-6): 251-266. Doi: 10.1007/s11068-008-9020-0
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Zima, AV; Kockskämper, J; Blatter, LA Cytosolic energy reserves determine the effect of glycolytic sugar phosphates on sarcoplasmic reticulum Ca2+ release in cat ventricular myocytes.
J Physiol. 2006; 577(Pt 1):281-293 Doi: 10.1113/jphysiol.2006.117242 [OPEN ACCESS]
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2005

Bondarenko, A; Svichar, N; Chesler, M Role of Na+-H+ and Na+-Ca2+ exchange in hypoxia-related acute astrocyte death.
Glia. 2005; 49(1):143-152 Doi: 10.1002/glia.20107
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von Lewinski, F; Keller, BU Mitochondrial Ca2+ buffering in hypoglossal motoneurons from mouse.
Neurosci Lett. 2005; 380(3):203-208 Doi: 10.1016/j.neulet.2005.01.010
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2004

Bito, V; Heinzel, FR; Weidemann, F; Dommke, C; van der Velden, J; Verbeken, E; Claus, P; Bijnens, B; De Scheerder, I; Stienen, GJ; Sutherland, GR; Sipido, KR Cellular mechanisms of contractile dysfunction in hibernating myocardium.
Circ Res. 2004; 94(6):794-801 Doi: 10.1161/01.RES.0000124934.84048.DF [OPEN ACCESS]
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Graziani, A; Bricko, V; Carmignani, M; Graier, WF; Groschner, K Cholesterol- and caveolin-rich membrane domains are essential for phospholipase A2-dependent EDHF formation.
CARDIOVASC RES. 2004; 64(2): 234-242. Doi: 10.1016/j.cardiores.2004.06.026 [OPEN ACCESS]
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Liu, X; Groschner, K; Ambudkar, IS Distinct Ca(2+)-permeable cation currents are activated by internal Ca(2+)-store depletion in RBL-2H3 cells and human salivary gland cells, HSG and HSY.
J Membr Biol. 2004; 200(2):93-104 Doi: 10.1007/s00232-004-0698-3
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2003

Heinemann, A; Schuligoi, R; Sabroe, I; Hartnell, A; Peskar, BA Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis.
J IMMUNOL. 2003; 170(9): 4752-4758. Doi: 10.4049/jimmunol.170.9.4752 [OPEN ACCESS]
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Textor, Z; Beer, M; Anetseder, M; Kostler, H; Kagerbauer, E; Kenn, W; Hahn, D; Roewer, N Caffeine impairs intramuscular energy balance in patients susceptible to malignant hyperthermia
Muscle Nerve. 2003; 28(3):353-358 Doi: 10.1002/mus.10445
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2002

Esenabhalu, VE; Cerimagic, M; Malli, R; Osibow, K; Levak-Frank, S; Frieden, M; Sattler, W; Kostner, GM; Zechner, R; Graier, WF Tissue-specific expression of human lipoprotein lipase in the vascular system affects vascular reactivity in transgenic mice.
Br J Pharmacol. 2002; 135(1):143-154 Doi: 10.1038/sj.bjp.0704440 [OPEN ACCESS]
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Frieden, M; Malli, R; Samardzija, M; Demaurex, N; Graier, WF Subplasmalemmal endoplasmic reticulum controls K(Ca) channel activity upon stimulation with a moderate histamine concentration in a human umbilical vein endothelial cell line.
J Physiol. 2002; 540(Pt 1):73-84 Doi: 10.1113/jphysiol.2002.017053 [OPEN ACCESS]
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Schuller-Petrovic, S; Stessel, H; Brunner, F Ca2+ mobilization in saphenous vein smooth muscle cells derived from patients with primary varicosity.
Eur J Clin Invest. 2002; 32(9):649-656 Doi: 10.1046%2Fj.1365-2362.2002.01023.x
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Spitaler, MM; Hammer, A; Malli, R; Graier, WF Functional analysis of histamine receptor subtypes involved in endothelium-mediated relaxation of the human uterine artery.
Clin Exp Pharmacol Physiol. 2002; 29(8):711-716 Doi: 10.1046%2Fj.1440-1681.2002.03704.x
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2000

Frieden, M; Graier, WF Subplasmalemmal ryanodine-sensitive Ca2+ release contributes to Ca2+-dependent K+ channel activation in a human umbilical vein endothelial cell line.
J Physiol. 2000; 524 Pt 3(1):715-724 Doi: 10.1111%2Fj.1469-7793.2000.00715.x [OPEN ACCESS]
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Paltauf-Doburzynska, J; Frieden, M; Spitaler, M; Graier, WF Histamine-induced Ca2+ oscillations in a human endothelial cell line depend on transmembrane ion flux, ryanodine receptors and endoplasmic reticulum Ca2+-ATPase.
J PHYSIOL-LONDON. 2000; 524 Pt 3(6): 701-713. Doi: 10.1111%2Fj.1469-7793.2000.00701.x [OPEN ACCESS]
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1999

Mombouli, JV; Holzmann, S; Kostner, GM; Graier, WF Potentiation of Ca2+ signaling in endothelial cells by 11,12-epoxyeicosatrienoic acid.
J Cardiovasc Pharmacol. 1999; 33(5):779-784 Doi: 10.1097%2F00005344-199905000-00015
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