Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: BREAST NEOPLASMS - GENETICS , . Treffer: 93

2020

Lord, SR; Collins, JM; Cheng, WC; Haider, S; Wigfield, S; Gaude, E; Fielding, BA; Pinnick, KE; Harjes, U; Segaran, A; Jha, P; Hoefler, G; Pollak, MN; Thompson, AM; Roy, PG; English, R; Adams, RF; Frezza, C; Buffa, FM; Karpe, F; Harris, AL Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.
Br J Cancer. 2020; 122(2):258-265 Doi: 10.1038/s41416-019-0665-5 [OPEN ACCESS]
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2018

Alunni-Fabbroni, M; Majunke, L; Trapp, EK; Tzschaschel, M; Mahner, S; Fasching, PA; Fehm, T; Schneeweiss, A; Beck, T; Lorenz, R; Friedl, TWP; Janni, W; Rack, B; SUCCESS Study Group Whole blood microRNAs as potential biomarkers in post-operative early breast cancer patients.
BMC Cancer. 2018; 18(1):141-141 Doi: 10.1186/s12885-018-4020-7 [OPEN ACCESS]
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2017

Bayraktar, R; Pichler, M; Kanlikilicer, P; Ivan, C; Bayraktar, E; Kahraman, N; Aslan, B; Oguztuzun, S; Ulasli, M; Arslan, A; Calin, G; Lopez-Berestein, G; Ozpolat, B MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase.
Oncotarget. 2017; 8(7): 11641-11658. Doi: 10.18632/oncotarget.14264 [OPEN ACCESS]
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Loibner, M; Oberauner-Wappis, L; Viertler, C; Groelz, D; Zatloukal, K Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation.
J Vis Exp. 2017; 8(130): Doi: 10.3791/55885 [OPEN ACCESS]
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Singer, CF; Tan, YY; Fitzal, F; Steger, GG; Egle, D; Reiner, A; Rudas, M; Moinfar, F; Gruber, C; Petru, E; Bartsch, R; Tendl, KA; Fuchs, D; Seifert, M; Exner, R; Balic, M; Bago-Horvath, Z; Filipits, M; Gnant, M; Austrian Breast and Colorectal Cancer Study Group Pathological Complete Response to Neoadjuvant Trastuzumab Is Dependent on HER2/CEP17 Ratio in HER2-Amplified Early Breast Cancer.
Clin Cancer Res. 2017; 23(14):3676-3683 Doi: 10.1158/1078-0432.CCR-16-2373 [OPEN ACCESS]
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Tiran, V; Stanzer, S; Heitzer, E; Meilinger, M; Rossmann, C; Lax, S; Tsybrovskyy, O; Dandachi, N; Balic, M Genetic profiling of putative breast cancer stem cells from malignant pleural effusions.
PLoS One. 2017; 12(4):e0175223-e0175223 Doi: 10.1371/journal.pone.0175223 [OPEN ACCESS]
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Trapp, EK; Majunke, L; Zill, B; Sommer, H; Andergassen, U; Koch, J; Harbeck, N; Mahner, S; Friedl, TWP; Janni, W; Rack, B; Alunni-Fabbroni, M LKB1 pro-oncogenic activity triggers cell survival in circulating tumor cells.
Mol Oncol. 2017; 11(11):1508-1526 Doi: 10.1002/1878-0261.12111 [OPEN ACCESS]
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2016

Belic, J; Koch, M; Ulz, P; Auer, M; Gerhalter, T; Mohan, S; Fischereder, K; Petru, E; Bauernhofer, T; Geigl, JB; Speicher, MR; Heitzer, E mFast-SeqS as a Monitoring and Pre-screening Tool for Tumor-Specific Aneuploidy in Plasma DNA.
Adv Exp Med Biol. 2016; 924:147-155 Doi: 10.1007/978-3-319-42044-8_28
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Cerk, S; Schwarzenbacher, D; Adiprasito, JB; Stotz, M; Hutterer, GC; Gerger, A; Ling, H; Calin, GA; Pichler, M Current Status of Long Non-Coding RNAs in Human Breast Cancer.
Int J Mol Sci. 2016; 17(9): Doi: 10.3390/ijms17091485 [OPEN ACCESS]
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Endris, V; Stenzinger, A; Pfarr, N; Penzel, R; Möbs, M; Lenze, D; Darb-Esfahani, S; Hummel, M; Sabine-Merkelbach-Bruse, M; Jung, A; Lehmann, U; Kreipe, H; Kirchner, T; Büttner, R; Jochum, W; Höfler, G; Dietel, M; Weichert, W; Schirmacher, P NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial.
Virchows Arch. 2016; 468(6):697-705 Doi: 10.1007/s00428-016-1919-8
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Jueckstock, J; Rack, B; Friedl, TW; Scholz, C; Steidl, J; Trapp, E; Tesch, H; Forstbauer, H; Lorenz, R; Rezai, M; Häberle, L; Alunni-Fabbroni, M; Schneeweiss, A; Beckmann, MW; Lichtenegger, W; Fasching, PA; Pantel, K; Janni, W; SUCCESS Study Group Detection of circulating tumor cells using manually performed immunocytochemistry (MICC) does not correlate with outcome in patients with early breast cancer - Results of the German SUCCESS-A- trial.
BMC Cancer. 2016; 16(10):401-401 Doi: 10.1186/s12885-016-2454-3 [OPEN ACCESS]
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Kammerer, S; Jahn, SW; Winter, E; Eidenhammer, S; Rezania, S; Regitnig, P; Pichler, M; Schreibmayer, W; Bauernhofer, T Critical evaluation of KCNJ3 gene product detection in human breast cancer: mRNA in situ hybridisation is superior to immunohistochemistry.
J Clin Pathol. 2016; 69(12):1116-1121 Doi: 10.1136/jclinpath-2016-203798 [OPEN ACCESS]
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Oberauner-Wappis, L; Loibner, M; Viertler, C; Groelz, D; Wyrich, R; Zatloukal, K Protocol for HER2 FISH determination on PAXgene-fixed and paraffin-embedded tissue in breast cancer.
Int J Exp Pathol. 2016; 97(2):202-206 Doi: 10.1111/iep.12185 [OPEN ACCESS]
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Rack, B; Zombirt, E; Trapp, E; Jückstock, J; Andergassen, U; Neugebauer, J; Kost, B; Weissenbacher, T; Jeschke, U; Schindlbeck, C; Janni, W; Alunni-Fabbroni, M Comparison of HER2 Expression in Primary Tumor and Disseminated Tumor Cells in the Bone Marrow of Breast Cancer Patients.
Oncology. 2016; 90(4):232-238 Doi: 10.1159/000442986 [OPEN ACCESS]
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Rasoulzadeh, Z; Ghods, R; Kazemi, T; Mirzadegan, E; Ghaffari-Tabrizi-Wizsy, N; Rezania, S; Kazemnejad, S; Arefi, S; Ghasemi, J; Vafaei, S; Mahmoudi, AR; Zarnani, AH Placental Kisspeptins Differentially Modulate Vital Parameters of Estrogen Receptor-Positive and -Negative Breast Cancer Cells.
PLoS One. 2016; 11(4):e0153684-e0153684 Doi: 10.1371/journal.pone.0153684 [OPEN ACCESS]
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Rezania, S; Kammerer, S; Li, C; Steinecker-Frohnwieser, B; Gorischek, A; DeVaney, TT; Verheyen, S; Passegger, CA; Tabrizi-Wizsy, NG; Hackl, H; Platzer, D; Zarnani, AH; Malle, E; Jahn, SW; Bauernhofer, T; Schreibmayer, W Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.
BMC Cancer. 2016; 16(1):628-628 Doi: 10.1186/s12885-016-2664-8 [OPEN ACCESS]
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Sigl, V; Owusu-Boaitey, K; Joshi, PA; Kavirayani, A; Wirnsberger, G; Novatchkova, M; Kozieradzki, I; Schramek, D; Edokobi, N; Hersl, J; Sampson, A; Odai-Afotey, A; Lazaro, C; Gonzalez-Suarez, E; Pujana, MA; Cimba, F; Heyn, H; Vidal, E; Cruickshank, J; Berman, H; Sarao, R; Ticevic, M; Uribesalgo, I; Tortola, L; Rao, S; Tan, Y; Pfeiler, G; Lee, EY; Bago-Horvath, Z; Kenner, L; Popper, H; Singer, C; Khokha, R; Jones, LP; Penninger, JM RANKL/RANK control Brca1 mutation- .
Cell Res. 2016; 26(7):761-774 Doi: 10.1038/cr.2016.69 [OPEN ACCESS]
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Todenhöfer, T; Hennenlotter, J; Dorner, N; Kühs, U; Aufderklamm, S; Rausch, S; Bier, S; Mischinger, J; Schellbach, D; Hauch, S; Feniuk, N; Bedke, J; Gakis, G; Stenzl, A; Schwentner, C Transcripts of circulating tumor cells detected by a breast cancer-specific platform correlate with clinical stage in bladder cancer patients.
J Cancer Res Clin Oncol. 2016; 142(5):1013-1020 Doi: 10.1007/s00432-016-2129-0
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2015

Benhaim, L; Zhang, W; Wakatsuki, T; Yang, D; Gerger, A; Bohanes, P; Paez, D; Loupakis, F; LaBonte, MJ; Ning, Y; El-Khoueiry, R; Ladner, R; Wilson, P; Zhang, H; Giamas, G; Stebbing, J; Lenz, HJ Genetic variants of kinase suppressors of Ras (KSR1) to predict survival in patients with ERα-positive advanced breast cancer.
Pharmacogenomics J. 2015; 15(3):235-240 Doi: 10.1038/tpj.2014.58
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Fitzal, F; Filipits, M; Rudas, M; Greil, R; Dietze, O; Samonigg, H; Lax, S; Herz, W; Dubsky, P; Bartsch, R; Kronenwett, R; Gnant, M The genomic expression test EndoPredict is a prognostic tool for identifying risk of local recurrence in postmenopausal endocrine receptor-positive, her2neu-negative breast cancer patients randomised within the prospective ABCSG 8 trial.
Br J Cancer. 2015; 112(8):1405-1410 Doi: 10.1038/bjc.2015.98 [OPEN ACCESS]
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Lebo, PB; Quehenberger, F; Kamolz, LP; Lumenta, DB The Angelina effect revisited: Exploring a media-related impact on public awareness.
Cancer. 2015; 121(22):3959-3964 Doi: 10.1002/cncr.29461 [OPEN ACCESS]
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Leitner, L; Jürets, A; Itariu, BK; Keck, M; Prager, G; Langer, F; Grablowitz, V; Zeyda, M; Stulnig, TM Osteopontin promotes aromatase expression and estradiol production in human adipocytes.
Breast Cancer Res Treat. 2015; 154(1):63-69 Doi: 10.1007/s10549-015-3603-0
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Li, C; Rezania, S; Kammerer, S; Sokolowski, A; Devaney, T; Gorischek, A; Jahn, S; Hackl, H; Groschner, K; Windpassinger, C; Malle, E; Bauernhofer, T; Schreibmayer, W Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line.
Sci Rep. 2015; 5(2):8364-8364 Doi: 10.1038/srep08364 [OPEN ACCESS]
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Schwarzenbacher, D; Stiegelbauer, V; Deutsch, A; Ress, AL; Aigelsreiter, A; Schauer, S; Wagner, K; Langsenlehner, T; Resel, M; Gerger, A; Ling, H; Ivan, C; Calin, GA; Hoefler, G; Rinner, B; Pichler, M Low spinophilin expression enhances aggressive biological behavior of breast cancer.
Oncotarget. 2015; 6(13):11191-11202 Doi: 10.18632/oncotarget.3586 [OPEN ACCESS]
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2014

Filipits, M; Nielsen, TO; Rudas, M; Greil, R; Stöger, H; Jakesz, R; Bago-Horvath, Z; Dietze, O; Regitnig, P; Gruber-Rossipal, C; Müller-Holzner, E; Singer, CF; Mlineritsch, B; Dubsky, P; Bauernhofer, T; Hubalek, M; Knauer, M; Trapl, H; Fesl, C; Schaper, C; Ferree, S; Liu, S; Cowens, JW; Gnant, M; Austrian Breast and Colorectal Cancer Study Group The PAM50 risk-of-recurrence score predicts risk for late distant recurrence after endocrine therapy in postmenopausal women with endocrine-responsive early breast cancer.
Clin Cancer Res. 2014; 20(5):1298-1305 Doi: 10.1158/1078-0432.CCR-13-1845 [OPEN ACCESS]
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Peintinger, F Using molecular profiles to tailor treatment in breast cancer: are they ready for prime time?
Curr Opin Obstet Gynecol. 2014; 26(1):21-26 Doi: 10.1097/GCO.0000000000000041
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Province, MA; Goetz, MP; Brauch, H; Flockhart, DA; Hebert, JM; Whaley, R; Suman, VJ; Schroth, W; Winter, S; Zembutsu, H; Mushiroda, T; Newman, WG; Lee, MT; Ambrosone, CB; Beckmann, MW; Choi, JY; Dieudonné, AS; Fasching, PA; Ferraldeschi, R; Gong, L; Haschke-Becher, E; Howell, A; Jordan, LB; Hamann, U; Kiyotani, K; Krippl, P; Lambrechts, D; Latif, A; Langsenlehner, U; Lorizio, W; Neven, P; Nguyen, AT; Park, BW; Purdie, CA; Quinlan, P; Renner, W; Schmidt, M; Schwab, M; Shin, JG; Stingl, JC; Wegman, P; Wingren, S; Wu, AH; Ziv, E; Zirpoli, G; Thompson, AM; Jordan, VC; Nakamura, Y; Altman, RB; Ames, MM; Weinshilboum, RM; Eichelbaum, M; Ingle, JN; Klein, TE; International Tamoxifen Pharmacogenomics Consortium CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations.
Clin Pharmacol Ther. 2014; 95(2):216-227 Doi: 10.1038/clpt.2013.186 [OPEN ACCESS]
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Singer, CF; Bennink, HJ; Natter, C; Steurer, S; Rudas, M; Moinfar, F; Appels, N; Visser, M; Kubista, E Antiestrogenic effects of the fetal estrogen estetrol in women with estrogen-receptor positive early breast cancer.
Carcinogenesis. 2014; 35(11):2447-2451 Doi: 10.1093/carcin/bgu144 [OPEN ACCESS]
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Trivanović, D; Nikolić, S; Krstić, J; Jauković, A; Mojsilović, S; Ilić, V; Okić-Djordjević, I; Santibanez, JF; Jovčić, G; Bugarski, D Characteristics of human adipose mesenchymal stem cells isolated from healthy and cancer affected people and their interactions with human breast cancer cell line MCF-7 in vitro.
Cell Biol Int. 2014; 38(2): 254-265. Doi: 10.1002/cbin.10198
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Winder, T; Giamas, G; Wilson, PM; Zhang, W; Yang, D; Bohanes, P; Ning, Y; Gerger, A; Stebbing, J; Lenz, HJ Insulin-like growth factor receptor polymorphism defines clinical outcome in estrogen receptor-positive breast cancer patients treated with tamoxifen.
Pharmacogenomics J. 2014; 14(1):28-34 Doi: 10.1038/tpj.2013.8
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2013

Absenger, G; Szkandera, J; Stotz, M; Pichler, M; Winder, T; Langsenlehner, T; Langsenlehner, U; Samonigg, H; Renner, W; Gerger, A A common and functional gene variant in the vascular endothelial growth factor a predicts clinical outcome in early-stage breast cancer.
Mol Carcinog. 2013; 52 Suppl 1(9):E96-102 Doi: 10.1002/mc.22028
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Aigner, B; Plötz, SG; Schaller, G Triple-negative breast cancer possibly transforming into malignant melanoma due to targeted therapy? A case report and review of literature.
Wien Med Wochenschr. 2013; 163(21-22): 495-498. Doi: 10.1007/s10354-013-0242-0 (- Case Report)
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Balic, M; Schwarzenbacher, D; Stanzer, S; Heitzer, E; Auer, M; Geigl, JB; Cote, RJ; Datar, RH; Dandachi, N Genetic and epigenetic analysis of putative breast cancer stem cell models.
BMC Cancer. 2013; 13(7):358-358 Doi: 10.1186/1471-2407-13-358 [OPEN ACCESS]
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Heitzer, E; Auer, M; Hoffmann, EM; Pichler, M; Gasch, C; Ulz, P; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Mohan, S; Pristauz, G; Lackner, C; Höfler, G; Eisner, F; Petru, E; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer.
Int J Cancer. 2013; 133(2):346-356 Doi: 10.1002/ijc.28030 [OPEN ACCESS]
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Heitzer, E; Lax, S; Lafer, I; Müller, SM; Pristauz, G; Ulz, P; Jahn, S; Högenauer, C; Petru, E; Speicher, MR; Geigl, JB Multiplex genetic cancer testing identifies pathogenic mutations in TP53 and CDH1 in a patient with bilateral breast and endometrial adenocarcinoma.
BMC Med Genet. 2013; 14(1):129-129 Doi: 10.1186/1471-2350-14-129 (- Case Report) [OPEN ACCESS]
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Lajin, B; Alhaj Sakur, A; Alachkar, A Association between polymorphisms in apoptotic genes and susceptibility for developing breast cancer in Syrian women.
Breast Cancer Res Treat. 2013; 138(2):611-619 Doi: 10.1007/s10549-013-2467-4
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Richtig, E; Schrama, D; Ugurel, S; Fried, I; Niederkorn, A; Massone, C; Becker, JC BRAF mutation analysis of only one single metastatic lesion can restrict the treatment of melanoma - a case report.
Br J Dermatol. 2013; 168(2):428-430 Doi: 10.1111/j.1365-2133.2012.11121.x (- Case Report)
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Stöger, H Are the new breast cancer subtypes (luminal A, B etc.) of practical impact? Yes].
Dtsch Med Wochenschr. 2013; 138(41):2096-2096 Doi: 10.1055/s-0033-1349531
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Tea, MK; Weghofer, A; Wagner, K; Singer, CF Association of BRCA1/2 mutations with FMR1 genotypes: effects on menarcheal and menopausal age.
Maturitas. 2013; 75(2):148-151 Doi: 10.1016/j.maturitas.2013.03.002
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2012

Labonte, MJ; Wilson, PM; Yang, D; Zhang, W; Ladner, RD; Ning, Y; Gerger, A; Bohanes, PO; Benhaim, L; El-Khoueiry, R; El-Khoueiry, A; Lenz, HJ The Cyclin D1 (CCND1) A870G polymorphism predicts clinical outcome to lapatinib and capecitabine in HER2-positive metastatic breast cancer.
Ann Oncol. 2012; 23(6):1455-1464 Doi: 10.1093/annonc/mdr445 [OPEN ACCESS]
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Lajin, B; Alhaj Sakur, A; Ghabreau, L; Alachkar, A Association of polymorphisms in one-carbon metabolizing genes with breast cancer risk in Syrian women.
Tumour Biol. 2012; 33(4):1133-1139 Doi: 10.1007/s13277-012-0354-y
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Mathiesen, RR; Fjelldal, R; Liestl, K; Due, EU; Geigl, JB; Riethdorf, S; Borgen, E; Rye, IH; Schneider, IJ; Obenauf, AC; Mauermann, O; Nilsen, G; Christian Lingjaerde, O; Brresen-Dale, AL; Pantel, K; Speicher, MR; Naume, B; Baumbusch, LO High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer.
Int J Cancer. 2012; 131(4):E405-E415 Doi: 10.1002/ijc.26444 [OPEN ACCESS]
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Pitroda, SP; Zhou, T; Sweis, RF; Filippo, M; Labay, E; Beckett, MA; Mauceri, HJ; Liang, H; Darga, TE; Perakis, S; Khan, SA; Sutton, HG; Zhang, W; Khodarev, NN; Garcia, JG; Weichselbaum, RR Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
PLoS One. 2012; 7(10): e46104-e46104. Doi: 10.1371/journal.pone.0046104 [OPEN ACCESS]
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Szkandera, J; Absenger, G; Stotz, M; Weissmueller, M; Winder, T; Langsenlehner, T; Samonigg, H; Renner, W; Schippinger, W; Gerger, A The Functional Polymorphism of Erythropoietin Gene rs1617640 G>T Is Not Associated with Susceptibility and Clinical Outcome of Early-stage Breast Cancer.
Anticancer Res. 2012; 32(8):3473-3478
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2011

Stacher, E; Boldt, V; Leibl, S; Halbwedl, I; Popper, HH; Ullmann, R; Tavassoli, FA; Moinfar, F Chromosomal aberrations as detected by array comparative genomic hybridization in early low-grade intraepithelial neoplasias of the breast.
Histopathology. 2011; 59(3):549-555 Doi: 10.1111/j.1365-2559.2011.03918.x
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2010

Bjelic-Radisic, V; Petru, E Hormonal contraception and breast cancer risk].
Wien Med Wochenschr. 2010; 160(19-20):483-486 Doi: 10.1007/s10354-010-0807-0
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Boldt, V; Stacher, E; Halbwedl, I; Popper, H; Hultschig, C; Moinfar, F; Ullmann, R; Tavassoli, FA Positioning of necrotic lobular intraepithelial neoplasias (LIN, grade 3) within the sequence of breast carcinoma progression.
Genes Chromosomes Cancer. 2010; 49(5):463-470 Doi: 10.1002/gcc.20756
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Gerger, A; Renner, W; Langsenlehner, T; Hofmann, G; Knechtel, G; Szkandera, J; Samonigg, H; Krippl, P; Langsenlehner, U Association of interleukin-10 gene variation with breast cancer prognosis.
Breast Cancer Res Treat. 2010; 119(3):701-705 Doi: 10.1007/s10549-009-0417-y
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Knechtel, G; Hofmann, G; Gerger, A; Renner, W; Langsenlehner, T; Szkandera, J; Wolf, G; Samonigg, H; Krippl, P; Langsenlehner, U Analysis of common germline polymorphisms as prognostic factors in patients with lymph node-positive breast cancer.
J Cancer Res Clin Oncol. 2010; 136(12):1813-1819 Doi: 10.1007/s00432-010-0839-2
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Moinfar, F Flat ductal intraepithelial neoplasia of the breast: evolution of Azzopardi's "clinging" concept.
Semin Diagn Pathol. 2010; 27(1):37-48 Doi: 10.1053/j.semdp.2009.12.005
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