Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: BLOOD-BRAIN BARRIER, . Treffer: 74

2018

Bernhart, E; Kogelnik, N; Prasch, J; Gottschalk, B; Goeritzer, M; Depaoli, MR; Reicher, H; Nusshold, C; Plastira, I; Hammer, A; Fauler, G; Malli, R; Graier, WF; Malle, E; Sattler, W 2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.
Redox Biol. 2018; 15: 441-451.
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Farzi, A; Fröhlich, EE; Holzer, P Gut Microbiota and the Neuroendocrine System.
Neurotherapeutics. 2018; 15(1): 5-22. [OPEN ACCESS]
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Zandl-Lang, M; Fanaee-Danesh, E; Sun, Y; Albrecher, NM; Gali, CC; Čančar, I; Kober, A; Tam-Amersdorfer, C; Stracke, A; Storck, SM; Saeed, A; Stefulj, J; Pietrzik, CU; Wilson, MR; Björkhem, I; Panzenboeck, U Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Biochim Biophys Acta. 2018; 1863(1):40-60
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2017

Baranyi, A; Amouzadeh-Ghadikolai, O; Lewinski, DV; Breitenecker, RJ; Stojakovic, T; März, W; Robier, C; Rothenhäusler, HB; Mangge, H; Meinitzer, A Beta-trace Protein as a new non-invasive immunological Marker for Quinolinic Acid-induced impaired Blood-Brain Barrier Integrity.
Sci Rep. 2017; 7:43642-43642 [OPEN ACCESS]
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Bode, GH; Coué, G; Freese, C; Pickl, KE; Sanchez-Purrà, M; Albaiges, B; Borrós, S; van Winden, EC; Tziveleka, LA; Sideratou, Z; Engbersen, JFJ; Singh, S; Albrecht, K; Groll, J; Möller, M; Pötgens, AJG; Schmitz, C; Fröhlich, E; Grandfils, C; Sinner, FM; Kirkpatrick, CJ; Steinbusch, HWM; Frank, HG; Unger, RE; Martinez-Martinez, P An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood-brain barrier uptake.
Nanomedicine. 2017; 13(3):1289-1300
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Kober, AC; Manavalan, APC; Tam-Amersdorfer, C; Holmér, A; Saeed, A; Fanaee-Danesh, E; Zandl, M; Albrecher, NM; Björkhem, I; Kostner, GM; Dahlbäck, B; Panzenboeck, U Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier.
Biochim Biophys Acta. 2017; 1862(6): 573-588.
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Lelu, S; Afadzi, M; Berg, S; Aslund, AK; Torp, SH; Sattler, W; de L Davies, C Primary Porcine Brain Endothelial Cells as In Vitro Model to Study Effects of Ultrasound and Microbubbles on Blood-Brain Barrier Function.
IEEE Trans Ultrason Ferroelectr Freq Control. 2017; 64(1): 281-290.
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Mayerhofer, R; Fröhlich, EE; Reichmann, F; Farzi, A; Kogelnik, N; Fröhlich, E; Sattler, W; Holzer, P Diverse action of lipoteichoic acid and lipopolysaccharide on neuroinflammation, blood-brain barrier disruption, and anxiety in mice.
Brain Behav Immun. 2017; 60:174-187 [OPEN ACCESS]
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Strenger, V; Farowski, F; Müller, C; Hofer, N; Dornbusch, HJ; Sperl, D; Lackner, H; Benesch, M; Urban, C Low penetration of caspofungin into cerebrospinal fluid following intravenous administration of standard doses.
Int J Antimicrob Agents. 2017; 50(2): 272-275.
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Voortman, MM; Pekar, T; Bachmayer, D; Archelos, JJ; Stojakovic, T; Scharnagl, H; Ropele, S; Pichler, A; Enzinger, C; Fuchs, S; Fazekas, F; Seifert-Held, T; Khalil, M Serum netrin-1 in relation to gadolinium-enhanced magnetic resonance imaging in early multiple sclerosis.
Mult Scler J Exp Transl Clin. 2017; 3(3): 2055217317727294-2055217317727294. [OPEN ACCESS]
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2016

Bosche, B; Molcanyi, M; Rej, S; Doeppner, TR; Obermann, M; Müller, DJ; Das, A; Hescheler, J; Macdonald, RL; Noll, T; Härtel, FV Low-Dose Lithium Stabilizes Human Endothelial Barrier by Decreasing MLC Phosphorylation and Universally Augments Cholinergic Vasorelaxation Capacity in a Direct Manner.
Front Physiol. 2016; 7: 593-593. [OPEN ACCESS]
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Fröhlich, EE; Farzi, A; Mayerhofer, R; Reichmann, F; Jačan, A; Wagner, B; Zinser, E; Bordag, N; Magnes, C; Fröhlich, E; Kashofer, K; Gorkiewicz, G; Holzer, P Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication.
Brain Behav Immun. 2016; 56(5):140-155 [OPEN ACCESS]
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Holzer, P Neuropeptides, Microbiota, and Behavior.
Int Rev Neurobiol. 2016; 131: 67-89.
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Leigh, R; Christensen, S; Campbell, BC; Marks, MP; Albers, GW; Lansberg, MG; DEFUSE 2 Investigators Pretreatment blood-brain barrier disruption and post-endovascular intracranial hemorrhage.
Neurology. 2016; 87(3): 263-269. [OPEN ACCESS]
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Nusshold, C; Üllen, A; Kogelnik, N; Bernhart, E; Reicher, H; Plastira, I; Glasnov, T; Zangger, K; Rechberger, G; Kollroser, M; Fauler, G; Wolinski, H; Weksler, BB; Romero, IA; Kohlwein, SD; Couraud, PO; Malle, E; Sattler, W Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
Free Radic Biol Med. 2016; 90: 59-74. [OPEN ACCESS]
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Rosenberg, GA; Wallin, A; Wardlaw, JM; Markus, HS; Montaner, J; Wolfson, L; Iadecola, C; Zlokovic, BV; Joutel, A; Dichgans, M; Duering, M; Schmidt, R; Korczyn, AD; Grinberg, LT; Chui, HC; Hachinski, V Consensus statement for diagnosis of subcortical small vessel disease
J CEREBR BLOOD F MET. 2016; 36(1): 6-25. [OPEN ACCESS]
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Sadovnick, AD; Traboulsee, AL; Bernales, CQ; Ross, JP; Forwell, AL; Yee, IM; Guillot-Noel, L; Fontaine, B; Cournu-Rebeix, I; Alcina, A; Fedetz, M; Izquierdo, G; Matesanz, F; Hilven, K; Dubois, B; Goris, A; Astobiza, I; Alloza, I; Antigüedad, A; Vandenbroeck, K; Akkad, DA; Aktas, O; Blaschke, P; Buttmann, M; Chan, A; Epplen, JT; Gerdes, LA; Kroner, A; Kubisch, C; Kümpfel, T; Lohse, P; Rieckmann, P; Zettl, UK; Zipp, F; Bertram, L; Lill, CM; Fernandez, O; Urbaneja, P; Leyva, L; Alvarez-Cermeño, JC; Arroyo, R; Garagorri, AM; García-Martínez, A; Villar, LM; Urcelay, E; Malhotra, S; Montalban, X; Comabella, M; Berger, T; Fazekas, F; Reindl, M; Schmied, MC; Zimprich, A; Vilariño-Güell, C Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients.
G3 (Bethesda). 2016; 6(7):2073-2079 [OPEN ACCESS]
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2015

Üllen, A; Nusshold, C; Glasnov, T; Saf, R; Cantillo, D; Eibinger, G; Reicher, H; Fauler, G; Bernhart, E; Hallstrom, S; Kogelnik, N; Zangger, K; Oliver Kappe, C; Malle, E; Sattler, W Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin.
Biochem Pharmacol. 2015; 93(4): 470-481. [OPEN ACCESS]
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2014

Birngruber, T; Ghosh, A; Hochmeister, S; Asslaber, M; Kroath, T; Pieber, TR; Sinner, F Long-term implanted cOFM probe causes minimal tissue reaction in the brain.
PLoS One. 2014; 9(3):e90221-e90221 [OPEN ACCESS]
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Birngruber, T; Raml, R; Gladdines, W; Gatschelhofer, C; Gander, E; Ghosh, A; Kroath, T; Gaillard, PJ; Pieber, TR; Sinner, F Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx,(®) /Doxil(®) -A Cerebral Open Flow Microperfusion Pilot Study.
J Pharm Sci. 2014; 103(7):1945-1948
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Chirackal Manavalan, AP; Kober, A; Metso, J; Lang, I; Becker, T; Hasslitzer, K; Zandl, M; Fanaee-Danesh, E; Pippal, JB; Sachdev, V; Kratky, D; Stefulj, J; Jauhiainen, M; Panzenboeck, U Phospholipid transfer protein is expressed in cerebrovascular endothelial cells and involved in high density lipoprotein biogenesis and remodeling at the blood-brain barrier.
J Biol Chem. 2014; 289(8):4683-4698 [OPEN ACCESS]
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Ghosh, A; Birngruber, T; Sattler, W; Kroath, T; Ratzer, M; Sinner, F; Pieber, TR Assessment of blood-brain barrier function and the neuroinflammatory response in the rat brain by using cerebral open flow microperfusion (cOFM).
PLoS One. 2014; 9(5):e98143-e98143 [OPEN ACCESS]
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Strenger, V; Meinitzer, A; Donnerer, J; Hofer, N; Dornbusch, HJ; Wanz, U; Seidel, MG; Sperl, D; Lackner, H; Schwinger, W; Sovinz, P; Benesch, M; Urban, C Amphotericin B transfer to CSF following intravenous administration of liposomal amphotericin B.
J Antimicrob Chemother. 2014; 69(9):2522-2526 [OPEN ACCESS]
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2013

Birngruber, T; Ghosh, A; Perez-Yarza, V; Kroath, T; Ratzer, M; Pieber, TR; Sinner, F Cerebral open flow microperfusion: a new in vivo technique for continuous measurement of substance transport across the intact blood-brain barrier.
Clin Exp Pharmacol Physiol. 2013; 40(12):864-871
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Hofrichter, J; Krohn, M; Schumacher, T; Lange, C; Feistel, B; Walbroel, B; Heinze, HJ; Crockett, S; Sharbel, TF; Pahnke, J Reduced Alzheimer's disease pathology by St. John's Wort treatment is independent of hyperforin and facilitated by ABCC1 and microglia activation in mice.
Curr Alzheimer Res. 2013; 10(10):1057-1069 [OPEN ACCESS]
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Kitic, M; Hochmeister, S; Wimmer, I; Bauer, J; Misu, T; Mader, S; Reindl, M; Fujihara, K; Lassmann, H; Bradl, M Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats.
Acta Neuropathol Commun. 2013; 1(11):5-5 [OPEN ACCESS]
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Löhr, M; Molcanyi, M; Poggenborg, J; Spuentrup, E; Runge, M; Röhn, G; Härtig, W; Hescheler, J; Hampl, JA Intracerebral administration of heat-inactivated Staphylococcus epidermidis enhances oncolysis and prolongs survival in a 9L orthotopic gliosarcoma model.
Cell Physiol Biochem. 2013; 31(4-5): 614-624. [OPEN ACCESS]
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Meister, S; Zlatev, I; Stab, J; Docter, D; Baches, S; Stauber, RH; Deutsch, M; Schmidt, R; Ropele, S; Windisch, M; Langer, K; Wagner, S; von Briesen, H; Weggen, S; Pietrzik, CU Nanoparticulate flurbiprofen reduces amyloid-β42 generation in an in vitro blood-brain barrier model.
Alzheimers Res Ther. 2013; 5(6):51-51 [OPEN ACCESS]
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Raber, G; Raber, T; Raml, R; Murko, M; Magnes, C; Francesconi, KA Determination of the trypanocidal drug melarsoprol and its conversion products in biological fluids with HPLC-ICPMS/ESMS.
Talanta. 2013; 116(10):876-881
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Üllen, A; Singewald, E; Konya, V; Fauler, G; Reicher, H; Nusshold, C; Hammer, A; Kratky, D; Heinemann, A; Holzer, P; Malle, E; Sattler, W Myeloperoxidase-derived oxidants induce blood-brain barrier dysfunction in vitro and in vivo.
PLoS One. 2013; 8(5):e64034-e64034 [OPEN ACCESS]
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2012

Fairless, R; Williams, SK; Hoffmann, DB; Stojic, A; Hochmeister, S; Schmitz, F; Storch, MK; Diem, R Preclinical retinal neurodegeneration in a model of multiple sclerosis.
J Neurosci. 2012; 32(16): 5585-5597. [OPEN ACCESS]
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Löhr, M; Molcanyi, M; Stenzel, W; Seifert, H; Tzouras, G; Röhn, G; Mohseni, D; Hampl, JA A novel experimental in vivo model of cerebral immunomodulation induced by inactivated Staphylococcus epidermidis.
J Neurosci Methods. 2012; 203(1): 89-95.
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Ullen, A; Fauler, G; Bernhart, E; Nusshold, C; Reicher, H; Leis, HJ; Malle, E; Sattler, W Phloretin ameliorates 2-chlorohexadecanal-mediated brain microvascular endothelial cell dysfunction in vitro.
Free Radic Biol Med. 2012; 53(9):1770-1781 [OPEN ACCESS]
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2011

Etschmaier, K; Becker, T; Eichmann, TO; Schweinzer, C; Scholler, M; Tam-Amersdorfer, C; Poeckl, M; Schuligoi, R; Kober, A; Chirackal Manavalan, AP; Rechberger, GN; Streith, IE; Zechner, R; Zimmermann, R; Panzenboeck, U Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers.
J Neurochem. 2011; 119(5): 1016-1028. [OPEN ACCESS]
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Schweinzer, C; Kober, A; Lang, I; Etschmaier, K; Scholler, M; Kresse, A; Sattler, W; Panzenboeck, U Processing of endogenous AβPP in blood-brain barrier endothelial cells is modulated by liver-X receptor agonists and altered cellular cholesterol homeostasis.
J Alzheimers Dis. 2011; 27(2):341-360
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2009

Holzer, P Opioid receptors in the gastrointestinal tract.
Regul Pept. 2009; 155(1-3): 11-17. [OPEN ACCESS]
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Kratzer, I; Bernhart, E; Wintersperger, A; Hammer, A; Waltl, S; Malle, E; Sperk, G; Wietzorrek, G; Dieplinger, H; Sattler, W Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier.
J Neurochem. 2009; 108(3): 707-718. [OPEN ACCESS]
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Schoderboeck, L; Adzemovic, M; Nicolussi, EM; Crupinschi, C; Hochmeister, S; Fischer, MT; Lassmann, H; Bradl, M The "window of susceptibility" for inflammation in the immature central nervous system is characterized by a leaky blood-brain barrier and the local expression of inflammatory chemokines.
Neurobiol Dis. 2009; 35(3): 368-375. [OPEN ACCESS]
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2008

Vellinga, MM; Oude Engberink, RD; Seewann, A; Pouwels, PJ; Wattjes, MP; van der Pol, SM; Pering, C; Polman, CH; de Vries, HE; Geurts, JJ; Barkhof, F Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement.
Brain. 2008; 131(Pt 3): 800-807. [OPEN ACCESS]
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2007

Bálint, Z; Krizbai, IA; Wilhelm, I; Farkas, AE; Párducz, A; Szegletes, Z; Váró, G Changes induced by hyperosmotic mannitol in cerebral endothelial cells: an atomic force microscopic study.
Eur Biophys J. 2007; 36(2):113-120
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Kratzer, I; Wernig, K; Panzenboeck, U; Bernhart, E; Reicher, H; Wronski, R; Windisch, M; Hammer, A; Malle, E; Zimmer, A; Sattler, W Apolipoprotein A-I coating of protamine-oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood-brain barrier.
J Control Release. 2007; 117(3): 301-311. [OPEN ACCESS]
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Mathey, EK; Derfuss, T; Storch, MK; Williams, KR; Hales, K; Woolley, DR; Al-Hayani, A; Davies, SN; Rasband, MN; Olsson, T; Moldenhauer, A; Velhin, S; Hohlfeld, R; Meinl, E; Linington, C Neurofascin as a novel target for autoantibody-mediated axonal injury.
J Exp Med. 2007; 204(10):2363-2372 [OPEN ACCESS]
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Meaney, S; Heverin, M; Panzenboeck, U; Ekström, L; Axelsson, M; Andersson, U; Diczfalusy, U; Pikuleva, I; Wahren, J; Sattler, W; Björkhem, I Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid.
J Lipid Res. 2007; 48(4): 944-951. [OPEN ACCESS]
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Panzenboeck, U; Andersson, U; Hansson, M; Sattler, W; Meaney, S; Björkhem, I On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis.
J Lipid Res. 2007; 48(5): 1167-1174. [OPEN ACCESS]
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Thoeringer, CK; Wultsch, T; Shahbazian, A; Painsipp, E; Holzer, P Multidrug-resistance gene 1-type p-glycoprotein (MDR1 p-gp) inhibition by tariquidar impacts on neuroendocrine and behavioral processing of stress.
Psychoneuroendocrinology. 2007; 32(8-10): 1028-1040. [OPEN ACCESS]
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Tokic, V; Barisic, I; Huzjak, N; Petkovic, G; Fumic, K; Paschke, E Enzyme replacement therapy in two patients with an advanced severe (Hurler) phenotype of mucopolysaccharidosis I.
Eur J Pediatr. 2007; 166(7):727-732 (- Case Report)
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Wilhelm, I; Farkas, AE; Nagyoszi, P; Váró, G; Bálint, Z; Végh, GA; Couraud, PO; Romero, IA; Weksler, B; Krizbai, IA Regulation of cerebral endothelial cell morphology by extracellular calcium.
Phys Med Biol. 2007; 52(20):6261-6274
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Wright, G; Davies, NA; Shawcross, DL; Hodges, SJ; Zwingmann, C; Brooks, HF; Mani, AR; Harry, D; Stadlbauer, V; Zou, Z; Zou, Z; Williams, R; Davies, C; Moore, KP; Jalan, R Endotoxemia produces coma and brain swelling in bile duct ligated rats.
Hepatology. 2007; 45(6):1517-1526 [OPEN ACCESS]
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2006

Hochmeister, S; Grundtner, R; Bauer, J; Engelhardt, B; Lyck, R; Gordon, G; Korosec, T; Kutzelnigg, A; Berger, JJ; Bradl, M; Bittner, RE; Lassmann, H Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis.
J Neuropathol Exp Neurol. 2006; 65(9): 855-865.
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Lumenta, DB; Plesnila, N; Kläsner, B; Baethmann, A; Pruneau, D; Schmid-Elsaesser, R; Zausinger, S Neuroprotective effects of a postischemic treatment with a bradykinin B2 receptor antagonist in a rat model of temporary focal cerebral ischemia.
Brain Res. 2006; 1069(1):227-234
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