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Publikationen

Suchbegriffe: BIOMARKERS, TUMOR - GENETICS , . Treffer: 76

2023

Ihrler, S; Stiefel, D; Jurmeister, P; Sandison, A; Chaston, N; Laco, J; Zidar, N; Brcic, L; Stoehr, R; Agaimy, A Salivary carcinosarcoma: insight into multistep pathogenesis indicates uniform origin as sarcomatoid variant of carcinoma ex pleomorphic adenoma with frequent heterologous elements.
Histopathology. 2023; 82(4):576-586 Doi: 10.1111/his.14840
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2022

Richards, R; Jour, G; Tafe, LJ; Pinto, A; Brčić, I; Linos, K; Kerr, DA Primary Pulmonary Round Cell Sarcomas: Multiple Potential Pitfalls for the Pathologist.
Int J Surg Pathol. 2022; 30(8):844-852 Doi: 10.1177/10668969221091586
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Robinson, I; Bertsch, A; Leithner, K; Stiegler, P; Olschewski, H; Hrzenjak, A Circulating microRNAs as molecular biomarkers for lung adenocarcinoma.
Cancer Biomark. 2022; 34(4):591-606 Doi: 10.3233/CBM-210205
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2021

Filipits, M; Rudas, M; Singer, CF; Fitzal, F; Bago-Horvath, Z; Greil, R; Balic, M; Lax, SF; Halper, S; Hulla, W; Wu, NC; Liu, X; Weidler, J; Bates, M; Hlauschek, D; Gnant, M; Dubsky, P ESR1, PGR, ERBB2, and MKi67 mRNA expression in postmenopausal women with hormone receptor-positive early breast cancer: results from ABCSG Trial 6.
ESMO Open. 2021; 6(4): 100228 Doi: 10.1016/j.esmoop.2021.100228 [OPEN ACCESS]
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Jean-Quartier, C; Jeanquartier, F; Ridvan, A; Kargl, M; Mirza, T; Stangl, T; Markaĉ, R; Jurada, M; Holzinger, A Mutation-based clustering and classification analysis reveals distinctive age groups and age-related biomarkers for glioma.
BMC MED INFORM DECIS. 2021; 21(1): 77-77. Doi: 10.1186/s12911-021-01420-1 [OPEN ACCESS]
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Schneider, R; Gademann, G; Ochel, HJ; Neumann, K; Jandrig, B; Hass, P; Walke, M; Schostak, M; Brunner, T; Christoph, F Functional and mutational analysis after radiation and cetuximab treatment on prostate carcinoma cell line DU145.
Radiat Oncol. 2021; 16(1): 137 Doi: 10.1186/s13014-021-01859-6 [OPEN ACCESS]
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2020

Benesch, M; Nemes, K; Neumayer, P; Hasselblatt, M; Timmermann, B; Bison, B; Ebetsberger-Dachs, G; Bourdeaut, F; Dufour, C; Biassoni, V; Morales La Madrid, A; Entz-Werle, N; Laithier, V; Quehenberger, F; Weis, S; Sumerauer, D; Siebert, R; Bens, S; Schneppenheim, R; Kool, M; Modena, P; Fouyssac, F; C Frühwald, M Spinal cord atypical teratoid/rhabdoid tumors in children: Clinical, genetic, and outcome characteristics in a representative European cohort.
Pediatr Blood Cancer. 2020; 67(1):e28022-e28022 Doi: 10.1002/pbc.28022
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Golob-Schwarzl, N; Puchas, P; Gogg-Kamerer, M; Weichert, W; Göppert, B; Haybaeck, J New Pancreatic Cancer Biomarkers eIF1, eIF2D, eIF3C and eIF6 Play a Major Role in Translational Control in Ductal Adenocarcinoma.
Anticancer Res. 2020; 40(6):3109-3118 Doi: 10.21873/anticanres.14292 [OPEN ACCESS]
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Matias-Guiu, X; Stanta, G; Carneiro, F; Ryska, A; Hoefler, G; Moch, H; European Society of Pathology (ESP) The leading role of pathology in assessing the somatic molecular alterations of cancer: Position Paper of the European Society of Pathology.
Virchows Arch. 2020; 476(4):491-497 Doi: 10.1007/s00428-020-02757-0 [OPEN ACCESS]
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Smolle, E; Leithner, K; Olschewski, H Oncogene addiction and tumor mutational burden in non-small-cell lung cancer: Clinical significance and limitations.
Thorac Cancer. 2020; 11(2):205-215 Doi: 10.1111/1759-7714.13246 [OPEN ACCESS]
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2019

Jilg, S; Rassner, M; Maier, J; Waldeck, S; Kehl, V; Follo, M; Philipp, U; Sauter, A; Specht, K; Mitschke, J; Lange, T; Bauer, S; Jost, PJ; Peschel, C; Duyster, J; Gaiser, T; Hohenberger, P; von Bubnoff, N Circulating cKIT and PDGFRA DNA indicates disease activity in Gastrointestinal Stromal Tumor (GIST).
Int J Cancer. 2019; 145(8):2292-2303 Doi: 10.1002/ijc.32282
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Saggini, A; Cerroni, L; Casini, B; Baciorri, F; Cota, C Primary intrafascial desmoplastic melanoma with pseudoglandular differentiation and aberrant cytokeratins expression: An exceptional presentation.
Pathol Res Pract. 2019; 215(12):152668-152668 Doi: 10.1016/j.prp.2019.152668 (- Case Report)
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2018

Alunni-Fabbroni, M; Majunke, L; Trapp, EK; Tzschaschel, M; Mahner, S; Fasching, PA; Fehm, T; Schneeweiss, A; Beck, T; Lorenz, R; Friedl, TWP; Janni, W; Rack, B; SUCCESS Study Group Whole blood microRNAs as potential biomarkers in post-operative early breast cancer patients.
BMC Cancer. 2018; 18(1):141-141 Doi: 10.1186/s12885-018-4020-7 [OPEN ACCESS]
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Gaksch, L; Kashofer, K; Heitzer, E; Quehenberger, F; Daga, S; Hofer, S; Halbwedl, I; Graf, R; Krisper, N; Hoefler, G; Zebisch, A; Sill, H; Wölfler, A Residual disease detection using targeted parallel sequencing predicts relapse in cytogenetically normal acute myeloid leukemia.
Am J Hematol. 2018; 93(1):23-30 Doi: 10.1002/ajh.24922 [OPEN ACCESS]
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Rinaldetti, S; Pfirrmann, M; Manz, K; Guilhot, J; Dietz, C; Panagiotidis, P; Spiess, B; Seifarth, W; Fabarius, A; Müller, M; Pagoni, M; Dimou, M; Dengler, J; Waller, CF; Brümmendorf, TH; Herbst, R; Burchert, A; Janβen, C; Goebeler, ME; Jost, PJ; Hanzel, S; Schafhausen, P; Prange-Krex, G; Illmer, T; Janzen, V; Klausmann, M; Eckert, R; Büschel, G; Kiani, A; Hofmann, WK; Mahon, FX; Saussele, S Effect of ABCG2, OCT1, and ABCB1 (MDR1) Gene Expression on Treatment-Free Remission in a EURO-SKI Subtrial.
Clin Lymphoma Myeloma Leuk. 2018; 18(4):266-271 Doi: 10.1016/j.clml.2018.02.004 [OPEN ACCESS]
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2017

Cuppens, T; Annibali, D; Coosemans, A; Trovik, J; Ter Haar, N; Colas, E; Garcia-Jimenez, A; Van de Vijver, K; Kruitwagen, RP; Brinkhuis, M; Zikan, M; Dundr, P; Huvila, J; Carpén, O; Haybaeck, J; Moinfar, F; Salvesen, HB; Stukan, M; Mestdagh, C; Zweemer, RP; Massuger, LF; Mallmann, MR; Wardelmann, E; Mints, M; Verbist, G; Thomas, D; Gommé, E; Hermans, E; Moerman, P; Bosse, T; Amant, F Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Clin Cancer Res. 2017; 23(5):1274-1285 Doi: 10.1158/1078-0432.CCR-16-2149 [OPEN ACCESS]
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Dandachi, N; Tiran, V; Lindenmann, J; Brcic, L; Fink-Neuboeck, N; Kashofer, K; Absenger, G; Bezan, A; Cote, RJ; Datar, R; Balic, M Frequency and clinical impact of preoperative circulating tumor cells in resectable non-metastatic lung adenocarcinomas.
Lung Cancer. 2017; 113(46):152-157 Doi: 10.1016/j.lungcan.2017.10.003
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Goblirsch, M; Richtig, G; Slaby, O; Berindan-Neagoe, I; Gerger, A; Pichler, M MicroRNAs as a tool to aid stratification of colorectal cancer patients and to guide therapy.
Pharmacogenomics. 2017; 18(10):1027-1038 Doi: 10.2217/pgs-2017-0004
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González-Vela, MDC; Curiel-Olmo, S; Derdak, S; Beltran, S; Santibañez, M; Martínez, N; Castillo-Trujillo, A; Gut, M; Sánchez-Pacheco, R; Almaraz, C; Cereceda, L; Llombart, B; Agraz-Doblas, A; Revert-Arce, J; López Guerrero, JA; Mollejo, M; Marrón, PI; Ortiz-Romero, P; Fernandez-Cuesta, L; Varela, I; Gut, I; Cerroni, L; Piris, MÁ; Vaqué, JP Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas.
J Invest Dermatol. 2017; 137(1):197-206 Doi: 10.1016/j.jid.2016.08.015 [OPEN ACCESS]
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Heitzer, E; Sunitsch, S; Gilg, MM; Lohberger, B; Rinner, B; Kashofer, K; Stündl, N; Ulz, P; Szkandera, J; Leithner, A; Liegl-Atzwanger, B Expanded molecular profiling of myxofibrosarcoma reveals potentially actionable targets.
Mod Pathol. 2017; 30(12):1698-1709 Doi: 10.1038/modpathol.2017.94 [OPEN ACCESS]
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Herold, T; Metzeler, KH; Vosberg, S; Hartmann, L; Jurinovic, V; Opatz, S; Konstandin, NP; Schneider, S; Zellmeier, E; Ksienzyk, B; Graf, A; Krebs, S; Blum, H; Cristina Sauerland, M; Büchner, T; Berdel, WE; Wörmann, BJ; Mansmann, U; Hiddemann, W; Bohlander, SK; Spiekermann, K; Greif, PA Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4.
Genes Chromosomes Cancer. 2017; 56(1): 75-86. Doi: 10.1002/gcc.22418
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Karlsson, J; Kroneis, T; Jonasson, E; Larsson, E; Ståhlberg, A Transcriptomic Characterization of the Human Cell Cycle in Individual Unsynchronized Cells.
J Mol Biol. 2017; 429(24):3909-3924 Doi: 10.1016/j.jmb.2017.10.011
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Kriegshäuser, G; Enko, D; Zitt, M; Oberwalder, M; Oberkanins, C; Öfner, D; Zeillinger, R; Maximilian Müller, H Comparison of a prototype reverse hybridization assay and MethyLight for detection of SFRP2 promotor methylation in fecal DNA.
Int J Biol Markers. 2017; 32(4):e467-e470-e467-e470 Doi: 10.5301/ijbm.5000289 [OPEN ACCESS]
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Perakis, S; Auer, M; Belic, J; Heitzer, E Advances in Circulating Tumor DNA Analysis.
Adv Clin Chem. 2017; 80(10):73-153 Doi: 10.1016/bs.acc.2016.11.005
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Pichler, M; Stiegelbauer, V; Vychytilova-Faltejskova, P; Ivan, C; Ling, H; Winter, E; Zhang, X; Goblirsch, M; Wulf-Goldenberg, A; Ohtsuka, M; Haybaeck, J; Svoboda, M; Okugawa, Y; Gerger, A; Hoefler, G; Goel, A; Slaby, O; Calin, GA Genome-Wide miRNA Analysis Identifies miR-188-3p as a Novel Prognostic Marker and Molecular Factor Involved in Colorectal Carcinogenesis.
Clin Cancer Res. 2017; 23(5):1323-1333 Doi: 10.1158/1078-0432.CCR-16-0497 [OPEN ACCESS]
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Planells-Palop, V; Hazazi, A; Feichtinger, J; Jezkova, J; Thallinger, G; Alsiwiehri, NO; Almutairi, M; Parry, L; Wakeman, JA; McFarlane, RJ Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis.
Mol Cancer. 2017; 16(1): 84-84. Doi: 10.1186/s12943-017-0653-4 [OPEN ACCESS]
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Rashed, MH; Kanlikilicer, P; Rodriguez-Aguayo, C; Pichler, M; Bayraktar, R; Bayraktar, E; Ivan, C; Filant, J; Silva, A; Aslan, B; Denizli, M; Mitra, R; Ozpolat, B; Calin, GA; Sood, AK; Abd-Ellah, MF; Helal, GK; Berestein, GL Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.
Oncotarget. 2017; 8(12):20145-20164 Doi: 10.18632/oncotarget.15525 [OPEN ACCESS]
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Richtig, G; Ehall, B; Richtig, E; Aigelsreiter, A; Gutschner, T; Pichler, M Function and Clinical Implications of Long Non-Coding RNAs in Melanoma.
Int J Mol Sci. 2017; 18(4): Doi: 10.3390/ijms18040715 [OPEN ACCESS]
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Saraggi, D; Salmaso, R; Valentini, E; Munari, G; Vindigni, V; Rugge, M; Fassan, M; Cerroni, L Pigmented trichoblastoma developed in a sebaceous nevus: HRAS mutation as a common molecular driver.
Pathol Res Pract. 2017; 213(7):860-862 Doi: 10.1016/j.prp.2017.03.012 (- Case Report)
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Schütte, M; Risch, T; Abdavi-Azar, N; Boehnke, K; Schumacher, D; Keil, M; Yildiriman, R; Jandrasits, C; Borodina, T; Amstislavskiy, V; Worth, CL; Schweiger, C; Liebs, S; Lange, M; Warnatz, HJ; Butcher, LM; Barrett, JE; Sultan, M; Wierling, C; Golob-Schwarzl, N; Lax, S; Uranitsch, S; Becker, M; Welte, Y; Regan, JL; Silvestrov, M; Kehler, I; Fusi, A; Kessler, T; Herwig, R; Landegren, U; Wienke, D; Nilsson, M; Velasco, JA; Garin-Chesa, P; Reinhard, C; Beck, S; Schäfer, R; Regenbrecht, CR; Henderson, D; Lange, B; Haybaeck, J; Keilholz, U; Hoffmann, J; Lehrach, H; Yaspo, ML Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Nat Commun. 2017; 8(2):14262-14262 Doi: 10.1038/ncomms14262 [OPEN ACCESS]
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Shen, P; Pichler, M; Chen, M; Calin, GA; Ling, H To Wnt or Lose: The Missing Non-Coding Linc in Colorectal Cancer.
Int J Mol Sci. 2017; 18(9): Doi: 10.3390/ijms18092003 [OPEN ACCESS]
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Stotz, M; Herzog, SA; Pichler, M; Smolle, M; Riedl, J; Rossmann, C; Bezan, A; Stöger, H; Renner, W; Berghold, A; Gerger, A Cancer Stem Cell Gene Variants in CD44 Predict Outcome in Stage II and Stage III Colon Cancer Patients.
Anticancer Res. 2017; 37(4):2011-2018 Doi: 10.21873/anticanres.11545 [OPEN ACCESS]
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Ulz, P; Heitzer, E; Geigl, JB; Speicher, MR Patient monitoring through liquid biopsies using circulating tumor DNA.
Int J Cancer. 2017; 141(5):887-896 Doi: 10.1002/ijc.30759 [OPEN ACCESS]
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2016

Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 Doi: 10.18632/oncotarget.9418 [OPEN ACCESS]
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Arriga, R; Caratelli, S; Coppola, A; Spagnoli, GC; Venditti, A; Amadori, S; Lanzilli, G; Lauro, D; Palomba, P; Sconocchia, T; Del Principe, MI; Maurillo, L; Buccisano, F; Capuani, B; Ferrone, S; Sconocchia, G Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage.
Oncotarget. 2016; 7(2): 2070-2079. Doi: 10.18632/oncotarget.6529 [OPEN ACCESS]
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Cerk, S; Schwarzenbacher, D; Adiprasito, JB; Stotz, M; Hutterer, GC; Gerger, A; Ling, H; Calin, GA; Pichler, M Current Status of Long Non-Coding RNAs in Human Breast Cancer.
Int J Mol Sci. 2016; 17(9): Doi: 10.3390/ijms17091485 [OPEN ACCESS]
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Hofman, P; Popper, HH Pathologists and liquid biopsies: to be or not to be?
Virchows Arch. 2016; 469(6):601-609 Doi: 10.1007/s00428-016-2004-z
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Kammerer, S; Jahn, SW; Winter, E; Eidenhammer, S; Rezania, S; Regitnig, P; Pichler, M; Schreibmayer, W; Bauernhofer, T Critical evaluation of KCNJ3 gene product detection in human breast cancer: mRNA in situ hybridisation is superior to immunohistochemistry.
J Clin Pathol. 2016; 69(12):1116-1121 Doi: 10.1136/jclinpath-2016-203798 [OPEN ACCESS]
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Ling, H; Krassnig, L; Bullock, MD; Pichler, M MicroRNAs in Testicular Cancer Diagnosis and Prognosis.
Urol Clin North Am. 2016; 43(1):127-134 Doi: 10.1016/j.ucl.2015.08.013
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Mayr, C; Beyreis, M; Wagner, A; Pichler, M; Neureiter, D; Kiesslich, T Deregulated MicroRNAs in Biliary Tract Cancer: Functional Targets and Potential Biomarkers.
Biomed Res Int. 2016; 2016(12):4805270-4805270 Doi: 10.1155/2016/4805270 [OPEN ACCESS]
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Miller, HC; Frampton, AE; Malczewska, A; Ottaviani, S; Stronach, EA; Flora, R; Kaemmerer, D; Schwach, G; Pfragner, R; Faiz, O; Kos-Kudła, B; Hanna, GB; Stebbing, J; Castellano, L; Frilling, A MicroRNAs associated with small bowel neuroendocrine tumours and their metastases.
Endocr Relat Cancer. 2016; 23(9):711-726 Doi: 10.1530/ERC-16-0044 [OPEN ACCESS]
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Perakis, SO; Thomas, JE; Pichler, M Non-coding RNAs Enabling Prognostic Stratification and Prediction of Therapeutic Response in Colorectal Cancer Patients.
Adv Exp Med Biol. 2016; 937(4):183-204 Doi: 10.1007/978-3-319-42059-2_10
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Rack, B; Zombirt, E; Trapp, E; Jückstock, J; Andergassen, U; Neugebauer, J; Kost, B; Weissenbacher, T; Jeschke, U; Schindlbeck, C; Janni, W; Alunni-Fabbroni, M Comparison of HER2 Expression in Primary Tumor and Disseminated Tumor Cells in the Bone Marrow of Breast Cancer Patients.
Oncology. 2016; 90(4):232-238 Doi: 10.1159/000442986 [OPEN ACCESS]
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Rausch, S; Hennenlotter, J; Scharpf, M; Teepe, K; Kühs, U; Aufderklamm, S; Bier, S; Mischinger, J; Gakis, G; Stenzl, A; Schwentner, C; Todenhöfer, T Prostate tumor overexpressed 1 expression in invasive urothelial carcinoma.
J Cancer Res Clin Oncol. 2016; 142(5):937-947 Doi: 10.1007/s00432-015-2107-y
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Schramm, A; Friedl, TW; Schochter, F; Scholz, C; de Gregorio, N; Huober, J; Rack, B; Trapp, E; Alunni-Fabbroni, M; Müller, V; Schneeweiss, A; Pantel, K; Meier-Stiegen, F; Hartkopf, A; Taran, FA; Wallwiener, D; Janni, W; Fehm, T Therapeutic intervention based on circulating tumor cell phenotype in metastatic breast cancer: concept of the DETECT study program.
Arch Gynecol Obstet. 2016; 293(2):271-281 Doi: 10.1007/s00404-015-3879-7
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Todenhöfer, T; Hennenlotter, J; Dorner, N; Kühs, U; Aufderklamm, S; Rausch, S; Bier, S; Mischinger, J; Schellbach, D; Hauch, S; Feniuk, N; Bedke, J; Gakis, G; Stenzl, A; Schwentner, C Transcripts of circulating tumor cells detected by a breast cancer-specific platform correlate with clinical stage in bladder cancer patients.
J Cancer Res Clin Oncol. 2016; 142(5):1013-1020 Doi: 10.1007/s00432-016-2129-0
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Trummer, O; Langsenlehner, U; Krenn-Pilko, S; Pieber, TR; Obermayer-Pietsch, B; Gerger, A; Renner, W; Langsenlehner, T Vitamin D and prostate cancer prognosis: a Mendelian randomization study.
World J Urol. 2016; 34(4):607-611 Doi: 10.1007/s00345-015-1646-9 [OPEN ACCESS]
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2015

Aoude, LG; Heitzer, E; Johansson, P; Gartside, M; Wadt, K; Pritchard, AL; Palmer, JM; Symmons, J; Gerdes, AM; Montgomery, GW; Martin, NG; Tomlinson, I; Kearsey, S; Hayward, NK POLE mutations in families predisposed to cutaneous melanoma.
Fam Cancer. 2015; 14(4):621-628 Doi: 10.1007/s10689-015-9826-8
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Botros, N; Cerroni, L; Shawwa, A; Green, PJ; Greer, W; Pasternak, S; Walsh, NM Cutaneous manifestations of angioimmunoblastic T-cell lymphoma: clinical and pathological characteristics.
Am J Dermatopathol. 2015; 37(4):274-283 Doi: 10.1097/DAD.0000000000000144
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Heitzer, E; Ulz, P; Geigl, JB Circulating tumor DNA as a liquid biopsy for cancer.
Clin Chem. 2015; 61(1):112-123 Doi: 10.1373/clinchem.2014.222679 [OPEN ACCESS]
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