Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: BRAF MUTATION, . Treffer: 32

2022

Dankner, M; Wang, Y; Fazelzad, R; Johnson, B; Nebhan, CA; Dagogo-Jack, I; Myall, NJ; Richtig, G; Bracht, JWP; Gerlinger, M; Shinozaki, E; Yoshino, T; Kotani, D; Fangusaro, JR; Gautschi, O; Mazieres, J; Sosman, JA; Kopetz, S; Subbiah, V; Davies, MA; Groover, AL; Sullivan, RJ; Flaherty, KT; Johnson, DB; Benedetti, A; Cescon, DW; Spreafico, A; Zogopoulos, G; Rose, AAN Clinical Activity of Mitogen-Activated Protein Kinase-Targeted Therapies in Patients With Non-V600 BRAF-Mutant Tumors.
JCO Precis Oncol. 2022; 6:e2200107 Doi: 10.1200/PO.22.00107
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2021

Brcic, I; Dawson, H; Gröchenig, HP; Högenauer, C; Kashofer, K Serrated Lesions in Inflammatory Bowel Disease: Genotype-Phenotype Correlation.
Int J Surg Pathol. 2021; 29(1):46-53 Doi: 10.1177/1066896920963798
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2019

Franck, C; Rosania, R; Franke, S; Haybaeck, J; Canbay, A; Venerito, M The BRAF Status May Predict Response to Sorafenib in Gastrointestinal Stromal Tumors Resistant to Imatinib, Sunitinib, and Regorafenib: Case Series and Review of the Literature.
Digestion. 2019; 99(2):179-184 Doi: 10.1159/000490886
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Liebs, S; Keilholz, U; Kehler, I; Schweiger, C; Haybäck, J; Nonnenmacher, A Detection of mutations in circulating cell-free DNA in relation to disease stage in colorectal cancer.
Cancer Med. 2019; 8(8):3761-3769 Doi: 10.1002/cam4.2219 [OPEN ACCESS]
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Margonis, GA; Buettner, S; Andreatos, N; Wagner, D; Sasaki, K; Barbon, C; Beer, A; Kamphues, C; Løes, IM; He, J; Pawlik, TM; Kaczirek, K; Poultsides, G; Lønning, PE; Cameron, JL; Mischinger, HJ; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Prognostic Factors Change Over Time After Hepatectomy for Colorectal Liver Metastases: A Multi-institutional, International Analysis of 1099 Patients.
ANN SURG. 2019; 269(6): 1129-1137. Doi: 10.1097/SLA.0000000000002664
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2018

Deshwar, A; Margonis, GA; Andreatos, N; Barbon, C; Wang, J; Buettner, S; Wagner, D; Sasaki, K; Beer, A; Løes, IM; Pikoulis, E; Damaskos, C; Garmpis, N; Kamphues, K; He, J; Kaczirek, K; Poultsides, G; Lønning, PE; Mischinger, HJ; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series.
Anticancer Res. 2018; 38(5):2891-2895 Doi: 10.21873/anticanres.12535 (- Case Report) [OPEN ACCESS]
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Margonis, GA; Buettner, S; Andreatos, N; Kim, Y; Wagner, D; Sasaki, K; Beer, A; Schwarz, C; Løes, IM; Smolle, M; Kamphues, C; He, J; Pawlik, TM; Kaczirek, K; Poultsides, G; Lønning, PE; Cameron, JL; Burkhart, RA; Gerger, A; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.
JAMA Surg. 2018; 153(7): e180996-e180996. Doi: 10.1001/jamasurg.2018.0996 [OPEN ACCESS]
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Margonis, GA; Buettner, S; Andreatos, N; Wagner, D; Sasaki, K; Barbon, C; Beer, A; Kamphues, C; Løes, IM; He, J; Pawlik, TM; Kaczirek, K; Poultsides, G; Lønning, PE; Cameron, JL; Mischinger, HJ; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Prognostic Factors Change Over Time After Hepatectomy for Colorectal Liver Metastases: A Multi-institutional, International Analysis of 1099 Patients.
Ann Surg. 2018; Doi: 10.1097/SLA.0000000000002664
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Posch, F; Silina, K; Leibl, S; Mündlein, A; Moch, H; Siebenhüner, A; Samaras, P; Riedl, J; Stotz, M; Szkandera, J; Stöger, H; Pichler, M; Stupp, R; van den Broek, M; Schraml, P; Gerger, A; Petrausch, U; Winder, T Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer.
Oncoimmunology. 2018; 7(2):e1378844-e1378844 Doi: 10.1080/2162402X.2017.1378844 [OPEN ACCESS]
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Veatch, JR; Lee, SM; Fitzgibbon, M; Chow, IT; Jesernig, B; Schmitt, T; Kong, YY; Kargl, J; Houghton, AM; Thompson, JA; McIntosh, M; Kwok, WW; Riddell, SR Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.
J CLIN INVEST. 2018; 128(4): 1563-1568. Doi: 10.1172/JCI98689 [OPEN ACCESS]
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2017

Fakhruddin, N; Jabbour, M; Novy, M; Tamim, H; Bahmad, H; Farhat, F; Zaatari, G; Aridi, T; Kriegshauser, G; Oberkanins, C; Mahfouz, R BRAF and NRAS Mutations in Papillary Thyroid Carcinoma and Concordance in BRAF Mutations Between Primary and Corresponding Lymph Node Metastases.
Sci Rep. 2017; 7(1): 4666-4666. Doi: 10.1038/s41598-017-04948-3 [OPEN ACCESS]
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Richtig, G; Hoeller, C; Kashofer, K; Aigelsreiter, A; Heinemann, A; Kwong, LN; Pichler, M; Richtig, E Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.
Br J Dermatol. 2017; 177(4):936-944 Doi: 10.1111/bjd.15436
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Yeh, I; Lang, UE; Durieux, E; Tee, MK; Jorapur, A; Shain, AH; Haddad, V; Pissaloux, D; Chen, X; Cerroni, L; Judson, RL; LeBoit, PE; McCalmont, TH; Bastian, BC; de la Fouchardière, A Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi.
Nat Commun. 2017; 8(1):644-644 Doi: 10.1038/s41467-017-00758-3 [OPEN ACCESS]
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2016

Richtig, G; Aigelsreiter, A; Kashofer, K; Talakic, E; Kupsa, R; Schaider, H; Richtig, E Two Case Reports of Rare BRAF Mutations in Exon 11 and Exon 15 with Discussion of Potential Treatment Options.
Case Rep Oncol. 2016; 9(3):543-546 Doi: 10.1159/000449125 (- Case Report) [OPEN ACCESS]
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van de Nes, J; Gessi, M; Sucker, A; Möller, I; Stiller, M; Horn, S; Scholz, SL; Pischler, C; Stadtler, N; Schilling, B; Zimmer, L; Hillen, U; Scolyer, RA; Buckland, ME; Lauriola, L; Pietsch, T; Waha, A; Schadendorf, D; Murali, R; Griewank, KG Targeted next generation sequencing reveals unique mutation profile of primary melanocytic tumors of the central nervous system.
J NEURO-ONCOL. 2016; 127(3): 435-444. Doi: 10.1007/s11060-015-2052-2 [OPEN ACCESS]
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Wiesner, T; Kutzner, H; Cerroni, L; Mihm, MC; Busam, KJ; Murali, R Genomic aberrations in spitzoid melanocytic tumours and their implications for diagnosis, prognosis and therapy.
Pathology. 2016; 48(2):113-131 Doi: 10.1016/j.pathol.2015.12.007 [OPEN ACCESS]
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2015

Kaczirek, K; Ciuleanu, TE; Vrbanec, D; Marton, E; Messinger, D; Liegl-Atzwanger, B; Wrba, F; Knittelfelder, R; Lindner, E; Zielinski, CC; Streubel, B; Brodowicz, T FOLFOX4 Plus Cetuximab for Patients With Previously Untreated Metastatic Colorectal Cancer According to Tumor RAS and BRAF Mutation Status: Updated Analysis of the CECOG/CORE 1.2.002 Study.
Clin Colorectal Cancer. 2015; 14(2):91-98 Doi: 10.1016/j.clcc.2014.12.003
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Langner, C Serrated and non-serrated precursor lesions of colorectal cancer.
Dig Dis. 2015; 33(1):28-37 Doi: 10.1159/000366032
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Ugurel, S; Loquai, C; Kähler, K; Hassel, J; Berking, C; Zimmer, L; Haubitz, I; Satzger, I; Müller-Brenne, T; Mikhaimer, NC; Becker, JC; Kilian, KJ; Schadendorf, D; Heinzerling, L; Kaatz, M; Utikal, J; Göppner, D; Pföhler, C; Pflugfelder, A; Mössner, R; Gutzmer, R; Dermatologic Cooperative Oncology Group (DeCOG) A multicenter DeCOG study on predictors of vemurafenib therapy outcome in melanoma: pretreatment impacts survival.
Ann Oncol. 2015; 26(3):573-582 Doi: 10.1093/annonc/mdu573 [OPEN ACCESS]
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Wiesner, T; Kutzner, H Morphological and genetic aspects of Spitz tumors].
Pathologe. 2015; 36(1): 37-43. Doi: 10.1007/s00292-014-1984-1
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Zalaudek, I; Ciarrocchi, A; Piana, S; Argenziano, G; Torricelli, F; Sancisi, V; Gandolfi, G; Longo, C; Moscarella, E; Banzi, C; Nicoli, D A novel BRAF mutation in association with primary amelanotic melanoma with oral metastases.
J Eur Acad Dermatol Venereol. 2015; 29(2):387-390 Doi: 10.1111/jdv.12358 (- Case Report)
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2014

Goldinger, SM; Zimmer, L; Schulz, C; Ugurel, S; Hoeller, C; Kaehler, KC; Schadendorf, D; Hassel, JC; Becker, J; Hauschild, A; Dummer, R; Dermatology Cooperative Oncology Group (DeCOG) Upstream mitogen-activated protein kinase (MAPK) pathway inhibition: MEK inhibitor followed by a BRAF inhibitor in advanced melanoma patients.
Eur J Cancer. 2014; 50(2):406-410 Doi: 10.1016/j.ejca.2013.09.014
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Rau, TT; Agaimy, A; Gehoff, A; Geppert, C; Jung, K; Knobloch, K; Langner, C; Lugli, A; Groenbus-Lurkin, I; Nagtegaal, ID; Rüschoff, J; Saegert, X; Sarbia, M; Schneider-Stock, R; Vieth, M; Zwarthoff, EC; Hartmann, A Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics.
Virchows Arch. 2014; 464(6):663-672 Doi: 10.1007/s00428-014-1569-7
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Saroufim, M; Novy, M; Taraif, S; Habib, RH; Loya, A; Rauscher, B; Kriegshäuser, G; Oberkanins, C; Khalifeh, I BRAF mutational epidemiology in dysplastic nevi: does different solar UV radiation exposure matter?
J Eur Acad Dermatol Venereol. 2014; 28(5): 615-625. Doi: 10.1111/jdv.12148
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2013

Busam, KJ; Sung, J; Wiesner, T; von Deimling, A; Jungbluth, A Combined BRAF(V600E)-positive melanocytic lesions with large epithelioid cells lacking BAP1 expression and conventional nevomelanocytes.
Am J Surg Pathol. 2013; 37(2):193-199 Doi: 10.1097/PAS.0b013e318263648c
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Buxhofer-Ausch, V; Ausch, C; Zeillinger, R; Oberkanins, C; Dandachi, N; Reiner-Concin, A; Kriegshäuser, G Duplex reverse-hybridization assay for the simultaneous detection of KRAS/BRAF mutations in FFPE-extracted genomic DNA from colorectal cancer specimens.
Dis Markers. 2013; 34(3):171-177 Doi: 10.3233/DMA-120960 [OPEN ACCESS]
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Griewank, KG; Westekemper, H; Murali, R; Mach, M; Schilling, B; Wiesner, T; Schimming, T; Livingstone, E; Sucker, A; Grabellus, F; Metz, C; Süsskind, D; Hillen, U; Speicher, MR; Woodman, SE; Steuhl, KP; Schadendorf, D Conjunctival melanomas harbor BRAF and NRAS mutations and copy number changes similar to cutaneous and mucosal melanomas.
Clin Cancer Res. 2013; 19(12):3143-3152 Doi: 10.1158/1078-0432.CCR-13-0163 [OPEN ACCESS]
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Hacker, E; Nagore, E; Cerroni, L; Woods, SL; Hayward, NK; Chapman, B; Montgomery, GW; Soyer, HP; Whiteman, DC; NRAS and BRAF Mutations in Cutaneous Melanoma and the Association with MC1R Genotype: Findings from Spanish and Austrian Populations.
J INVEST DERMATOL. 2013; 133(4): 1027-1033. Doi: 10.1038/jid.2012.385 [OPEN ACCESS]
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2012

Wiesner, T; Murali, R; Fried, I; Cerroni, L; Busam, K; Kutzner, H; Bastian, BC A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression.
Am J Surg Pathol. 2012; 36(6):818-830 Doi: 10.1097/PAS.0b013e3182498be5 [OPEN ACCESS]
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2009

Vilkin, A; Niv, Y; Nagasaka, T; Morgenstern, S; Levi, Z; Fireman, Z; Fuerst, F; Goel, A; Boland, CR Microsatellite instability, MLH1 promoter methylation, and BRAF mutation analysis in sporadic colorectal cancers of different ethnic groups in Israel.
Cancer. 2009; 115(4):760-769 Doi: 10.1002/cncr.24019 [OPEN ACCESS]
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2008

Houben, R; Vetter-Kauczok, CS; Ortmann, S; Rapp, UR; Broecker, EB; Becker, JC Phospho-ERK staining is a poor indicator of the mutational status of BRAF and NRAS in human melanoma.
J Invest Dermatol. 2008; 128(8):2003-2012 Doi: 10.1038/jid.2008.30 [OPEN ACCESS]
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Schrama, D; Keller, G; Houben, R; Ziegler, CG; Vetter-Kauczok, CS; Ugurel, S; Becker, JC BRAFV600E mutations in malignant melanoma are associated with increased expressions of BAALC.
J Carcinog. 2008; 7(1):1-1 Doi: 10.1186/1477-3163-7-1 [OPEN ACCESS]
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