Suchbegriffe: APOPTOSIS - GENETICS , . Treffer: 46
Balihodzic, A; Prinz, F; Dengler, MA; Calin, GA; Jost, PJ; Pichler, M
Non-coding RNAs and ferroptosis: potential implications for cancer therapy.
Cell Death Differ. 2022; 29(6):1094-1106
Doi: 10.1038/s41418-022-00998-x
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Edwards-Hicks, J; Su, H; Mangolini, M; Yoneten, KK; Wills, J; Rodriguez-Blanco, G; Young, C; Cho, K; Barker, H; Muir, M; Guerrieri, AN; Li, XF; White, R; Manasterski, P; Mandrou, E; Wills, K; Chen, J; Abraham, E; Sateri, K; Qian, BZ; Bankhead, P; Arends, M; Gammoh, N; von, Kriegsheim, A; Patti, GJ; Sims, AH; Acosta, JC; Brunton, V; Kranc, KR; Christophorou, M; Pearce, EL; Ringshausen, I; Finch, AJ
MYC sensitises cells to apoptosis by driving energetic demand.
Nat Commun. 2022; 13(1): 4674
Doi: 10.1038/s41467-022-32368-z
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Bugger, H; Pfeil, K
Mitochondrial ROS in myocardial ischemia reperfusion and remodeling.
Biochim Biophys Acta Mol Basis Dis. 2020; 1866(7):165768-165768
Doi: 10.1016/j.bbadis.2020.165768
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Chortis, V; Taylor, AE; Doig, CL; Walsh, MD; Meimaridou, E; Jenkinson, C; Rodriguez-Blanco, G; Ronchi, CL; Jafri, A; Metherell, LA; Hebenstreit, D; Dunn, WB; Arlt, W; Foster, PA
Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma.
Endocrinology. 2018; 159(8): 2836-2849.
Doi: 10.1210/en.2018-00014
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Arzt, L; Halbwedl, I; Gogg-Kamerer, M; Popper, HH
Signal Transducer and Activator of Transcription 1 (STAT1) Knock-down Induces Apoptosis in Malignant Pleural Mesothelioma.
Pathol Oncol Res. 2017; 23(3):595-605
Doi: 10.1007/s12253-016-0157-3
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Deutsch, AJA; Rinner, B; Pichler, M; Prochazka, K; Pansy, K; Bischof, M; Fechter, K; Hatzl, S; Feichtinger, J; Wenzl, K; Frisch, MT; Stiegelbauer, V; Prokesch, A; Krogsdam, A; Sill, H; Thallinger, GG; Greinix, HT; Wang, C; Beham-Schmid, C; Neumeister, P
NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.
Cancer Res. 2017; 77(9):2375-2386
Doi: 10.1158/0008-5472.CAN-16-2320
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Thangaratnarajah, C; Dinger, K; Vohlen, C; Klaudt, C; Nawabi, J; Lopez Garcia, E; Kwapiszewska, G; Dobner, J; Nüsken, KD; van Koningsbruggen-Rietschel, S; von Hörsten, S; Dötsch, J; Alejandre Alcázar, MA
Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction.
Am J Physiol Lung Cell Mol Physiol. 2017; 313(3):L491-L506
Doi: 10.1152/ajplung.00432.2016
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Wohlkoenig, C; Leithner, K; Olschewski, A; Olschewski, H; Hrzenjak, A
TR3 is involved in hypoxia-induced apoptosis resistance in lung cancer cells downstream of HIF-1α.
Lung Cancer. 2017; 111(3):15-22
Doi: 10.1016/j.lungcan.2017.06.013
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Fisser, MC; Rommer, A; Steinleitner, K; Heller, G; Herbst, F; Wiese, M; Glimm, H; Sill, H; Wieser, R
Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.
Mol Carcinog. 2015; 54(12):1815-1819
Doi: 10.1002/mc.22252
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Hibar, DP; Stein, JL; Renteria, ME; Arias-Vasquez, A; Desrivières, S; Jahanshad, N; Toro, R; Wittfeld, K; Abramovic, L; Andersson, M; Aribisala, BS; Armstrong, NJ; Bernard, M; Bohlken, MM; Boks, MP; Bralten, J; Brown, AA; Chakravarty, MM; Chen, Q; Ching, CR; Cuellar-Partida, G; den Braber, A; Giddaluru, S; Goldman, AL; Grimm, O; Guadalupe, T; Hass, J; Woldehawariat, G; Holmes, AJ; Hoogman, M; Janowitz, D; Jia, T; Kim, S; Klein, M; Kraemer, B; Lee, PH; Olde Loohuis, LM; Luciano, M; Macare, C; Mather, KA; Mattheisen, M; Milaneschi, Y; Nho, K; Papmeyer, M; Ramasamy, A; Risacher, SL; Roiz-Santiañez, R; Rose, EJ; Salami, A; Sämann, PG; Schmaal, L; Schork, AJ; Shin, J; Strike, LT; Teumer, A; van Donkelaar, MM; van Eijk, KR; Walters, RK; Westlye, LT; Whelan, CD; Winkler, AM; Zwiers, MP; Alhusaini, S; Athanasiu, L; Ehrlich, S; Hakobjan, MM; Hartberg, CB; Haukvik, UK; Heister, AJ; Hoehn, D; Kasperaviciute, D; Liewald, DC; Lopez, LM; Makkinje, RR; Matarin, M; Naber, MA; McKay, DR; Needham, M; Nugent, AC; Pütz, B; Royle, NA; Shen, L; Sprooten, E; Trabzuni, D; van der Marel, SS; van Hulzen, KJ; Walton, E; Wolf, C; Almasy, L; Ames, D; Arepalli, S; Assareh, AA; Bastin, ME; Brodaty, H; Bulayeva, KB; Carless, MA; Cichon, S; Corvin, A; Curran, JE; Czisch, M; de Zubicaray, GI; Dillman, A; Duggirala, R; Dyer, TD; Erk, S; Fedko, IO; Ferrucci, L; Foroud, TM; Fox, PT; Fukunaga, M; Gibbs, JR; Göring, HH; Green, RC; Guelfi, S; Hansell, NK; Hartman, CA; Hegenscheid, K; Heinz, A; Hernandez, DG; Heslenfeld, DJ; Hoekstra, PJ; Holsboer, F; Homuth, G; Hottenga, JJ; Ikeda, M; Jack, CR; Jenkinson, M; Johnson, R; Kanai, R; Keil, M; Kent, JW; Kochunov, P; Kwok, JB; Lawrie, SM; Liu, X; Longo, DL; McMahon, KL; Meisenzahl, E; Melle, I; Mohnke, S; Montgomery, GW; Mostert, JC; Mühleisen, TW; Nalls, MA; Nichols, TE; Nilsson, LG; Nöthen, MM; Ohi, K; Olvera, RL; Perez-Iglesias, R; Pike, GB; Potkin, SG; Reinvang, I; Reppermund, S; Rietschel, M; Romanczuk-Seiferth, N; Rosen, GD; Rujescu, D; Schnell, K; Schofield, PR; Smith, C; Steen, VM; Sussmann, JE; Thalamuthu, A; Toga, AW; Traynor, BJ; Troncoso, J; Turner, JA; Valdés Hernández, MC; van 't Ent, D; van der Brug, M; van der Wee, NJ; van Tol, MJ; Veltman, DJ; Wassink, TH; Westman, E; Zielke, RH; Zonderman, AB; Ashbrook, DG; Hager, R; Lu, L; McMahon, FJ; Morris, DW; Williams, RW; Brunner, HG; Buckner, RL; Buitelaar, JK; Cahn, W; Calhoun, VD; Cavalleri, GL; Crespo-Facorro, B; Dale, AM; Davies, GE; Delanty, N; Depondt, C; Djurovic, S; Drevets, WC; Espeseth, T; Gollub, RL; Ho, BC; Hoffmann, W; Hosten, N; Kahn, RS; Le Hellard, S; Meyer-Lindenberg, A; Müller-Myhsok, B; Nauck, M; Nyberg, L; Pandolfo, M; Penninx, BW; Roffman, JL; Sisodiya, SM; Smoller, JW; van Bokhoven, H; van Haren, NE; Völzke, H; Walter, H; Weiner, MW; Wen, W; White, T; Agartz, I; Andreassen, OA; Blangero, J; Boomsma, DI; Brouwer, RM; Cannon, DM; Cookson, MR; de Geus, EJ; Deary, IJ; Donohoe, G; Fernández, G; Fisher, SE; Francks, C; Glahn, DC; Grabe, HJ; Gruber, O; Hardy, J; Hashimoto, R; Hulshoff Pol, HE; Jönsson, EG; Kloszewska, I; Lovestone, S; Mattay, VS; Mecocci, P; McDonald, C; McIntosh, AM; Ophoff, RA; Paus, T; Pausova, Z; Ryten, M; Sachdev, PS; Saykin, AJ; Simmons, A; Singleton, A; Soininen, H; Wardlaw, JM; Weale, ME; Weinberger, DR; Adams, HH; Launer, LJ; Seiler, S; Schmidt, R; Chauhan, G; Satizabal, CL; Becker, JT; Yanek, L; van der Lee, SJ; Ebling, M; Fischl, B; Longstreth, WT; Greve, D; Schmidt, H; Nyquist, P; Vinke, LN; van Duijn, CM; Xue, L; Mazoyer, B; Bis ...
Common genetic variants influence human subcortical brain structures.
Nature. 2015; 520(7546): 224-229.
Doi: 10.1038/nature14101
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Juntermanns, B; Sydor, S; Kaiser, GM; Jaradat, D; Mertens, JC; Sotiropoulos, GC; Swoboda, S; Neuhaus, JP; Meng, W; Mathé, Z; Baba, HA; Canbay, A; Paul, A; Fingas, CD
Polo-like kinase 3 is associated with improved overall survival in cholangiocarcinoma.
Liver Int. 2015; 35(11):2448-2457
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Lindner, E; Glatz, W; Schwab, C; El-Shabrawi, Y; Mossböck, G
Analysis of functional polymorphisms in apoptosis-related genes in primary open angle glaucoma.
Mol Vis. 2015; 21(7):1340-1344
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Ress, AL; Perakis, S; Pichler, M
microRNAs and Colorectal Cancer.
Adv Exp Med Biol. 2015; 889(6):89-103
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Ress, AL; Stiegelbauer, V; Winter, E; Schwarzenbacher, D; Kiesslich, T; Lax, S; Jahn, S; Deutsch, A; Bauernhofer, T; Ling, H; Samonigg, H; Gerger, A; Hoefler, G; Pichler, M
MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients.
Mol Carcinog. 2015; 54(11):1442-1450
Doi: 10.1002/mc.22218
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Schwamb, B; Pick, R; Fernández, SB; Völp, K; Heering, J; Dötsch, V; Bösser, S; Jung, J; Beinoraviciute-Kellner, R; Wesely, J; Zörnig, I; Hammerschmidt, M; Nowak, M; Penzel, R; Zatloukal, K; Joos, S; Rieker, RJ; Agaimy, A; Söder, S; Reid-Lombardo, KM; Kendrick, ML; Bardsley, MR; Hayashi, Y; Asuzu, DT; Syed, SA; Ordog, T; Zörnig, M
FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors.
Int J Cancer. 2015; 137(6):1318-1329
Doi: 10.1002/ijc.29498
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Troppan, K; Hofer, S; Wenzl, K; Lassnig, M; Pursche, B; Steinbauer, E; Wiltgen, M; Zulus, B; Renner, W; Beham-Schmid, C; Deutsch, A; Neumeister, P
Frequent down regulation of the tumor suppressor gene a20 in multiple myeloma.
PLoS One. 2015; 10(4):e0123922-e0123922
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Deutsch, AJ; Rinner, B; Wenzl, K; Pichler, M; Troppan, K; Steinbauer, E; Schwarzenbacher, D; Reitter, S; Feichtinger, J; Tierling, S; Prokesch, A; Scheideler, M; Krogsdam, A; Thallinger, GG; Schaider, H; Beham-Schmid, C; Neumeister, P
NR4A1-mediated apoptosis suppresses lymphomagenesis and is associated with a favorable cancer-specific survival in patients with aggressive B-cell lymphomas.
Blood. 2014; 123(15):2367-2377
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Fröhlich, LF; Mrakovcic, M; Smole, C; Lahiri, P; Zatloukal, K
Epigenetic silencing of apoptosis-inducing gene expression can be efficiently overcome by combined SAHA and TRAIL treatment in uterine sarcoma cells.
PLoS One. 2014; 9(3):e91558-e91558
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Kong, P; Racedo, SE; Macchiarulo, S; Hu, Z; Carpenter, C; Guo, T; Wang, T; Zheng, D; Morrow, BE
Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.
Hum Mol Genet. 2014; 23(16): 4215-4231.
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Pavo, N; Zimmermann, M; Pils, D; Mildner, M; Petrási, Z; Petneházy, Ö; Fuzik, J; Jakab, A; Gabriel, C; Sipos, W; Maurer, G; Gyöngyösi, M; Ankersmit, HJ
Long-acting beneficial effect of percutaneously intramyocardially delivered secretome of apoptotic peripheral blood cells on porcine chronic ischemic left ventricular dysfunction.
Biomaterials. 2014; 35(11): 3541-3550.
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Pichler, M; Ress, AL; Winter, E; Stiegelbauer, V; Karbiener, M; Schwarzenbacher, D; Scheideler, M; Ivan, C; Jahn, SW; Kiesslich, T; Gerger, A; Bauernhofer, T; Calin, GA; Hoefler, G
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Schelch, K; Hoda, MA; Klikovits, T; Münzker, J; Ghanim, B; Wagner, C; Garay, T; Laszlo, V; Setinek, U; Dome, B; Filipits, M; Pirker, C; Heffeter, P; Selzer, E; Tovari, J; Torok, S; Kenessey, I; Holzmann, K; Grasl-Kraupp, B; Marian, B; Klepetko, W; Berger, W; Hegedus, B; Grusch, M
Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.
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Thurner, EM; Krenn-Pilko, S; Langsenlehner, U; Renner, W; Gerger, A; Kapp, KS; Langsenlehner, T
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Wong, WW; Vince, JE; Lalaoui, N; Lawlor, KE; Chau, D; Bankovacki, A; Anderton, H; Metcalf, D; O'Reilly, L; Jost, PJ; Murphy, JM; Alexander, WS; Strasser, A; Vaux, DL; Silke, J
cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner.
Blood. 2014; 123(16):2562-2572
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Stiegler, P; Sereinigg, M; Puntschart, A; Bradatsch, A; Seifert-Held, T; Wiederstein-Grasser, I; Leber, B; Stadelmeyer, E; Dandachi, N; Zelzer, S; Iberer, F; Stadlbauer, V
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Doi: 10.1097/00000372-199502000-00002
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