Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: APOPTOSIS - DRUG EFFECTS , . Treffer: 156

2018

Durchschein, C; Hufner, A; Rinner, B; Stallinger, A; Deutsch, A; Lohberger, B; Bauer, R; Kretschmer, N Synthesis of Novel Shikonin Derivatives and Pharmacological Effects of Cyclopropylacetylshikonin on Melanoma Cells.
Molecules. 2018; 23(11): [OPEN ACCESS]
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Jahanafrooz, Z; Stallinger, A; Anders, I; Kleinegger, F; Lohberger, B; Durchschein, C; Bauer, R; Deutsch, A; Rinner, B; Kretschmer, N Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells.
Phytomedicine. 2018; 49(11):32-40
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Kretschmer, N; Deutsch, A; Durchschein, C; Rinner, B; Stallinger, A; Higareda-Almaraz, JC; Scheideler, M; Lohberger, B; Bauer, R Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction.
Molecules. 2018; 23(11): [OPEN ACCESS]
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Lohberger, B; Wagner, S; Wohlmuther, J; Kaltenegger, H; Stuendl, N; Leithner, A; Rinner, B; Kunert, O; Bauer, R; Kretschmer, N Periplocin, the most anti-proliferative constituent of Periploca sepium, specifically kills liposarcoma cells by death receptor mediated apoptosis.
Phytomedicine. 2018; 51:162-170
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2017

Bonyadi Rad, E; Mostofi, S; Katschnig, M; Schmutz, P; Pawelkiewicz, M; Willumeit-Römer, R; Schäfer, U; Weinberg, A Differential apoptotic response of MC3T3-E1 pre-osteoblasts to biodegradable magnesium alloys in an in vitro direct culture model.
J Mater Sci Mater Med. 2017; 28(10):155-155 [OPEN ACCESS]
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Enzenhofer, E; Kadletz, L; Stanisz, I; Kotowski, U; Seemann, R; Schmid, R; Thurnher, D; Heiduschka, G Effect of the histone deacetylase inhibitor resminostat on head and neck squamous cell carcinoma cell lines.
Head Neck. 2017; 39(5):900-907
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Madreiter-Sokolowski, CT; Sokolowski, AA; Graier, WF Dosis Facit Sanitatem-Concentration-Dependent Effects of Resveratrol on Mitochondria.
Nutrients. 2017; 9(10): [OPEN ACCESS]
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Račkauskas, R; Zhou, D; Ūselis, S; Strupas, K; Herr, I; Schemmer, P Sulforaphane sensitizes human cholangiocarcinoma to cisplatin via the downregulation of anti-apoptotic proteins.
Oncol Rep. 2017; 37(6):3660-3666 [OPEN ACCESS]
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2016

Arriga, R; Caratelli, S; Coppola, A; Spagnoli, GC; Venditti, A; Amadori, S; Lanzilli, G; Lauro, D; Palomba, P; Sconocchia, T; Del Principe, MI; Maurillo, L; Buccisano, F; Capuani, B; Ferrone, S; Sconocchia, G Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage.
Oncotarget. 2016; 7(2): 2070-2079. [OPEN ACCESS]
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Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591
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Koyani, CN; Kitz, K; Rossmann, C; Bernhart, E; Huber, E; Trummer, C; Windischhofer, W; Sattler, W; Malle, E Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death.
Biochem Pharmacol. 2016; 104:29-41 [OPEN ACCESS]
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Madreiter-Sokolowski, CT; Gottschalk, B; Parichatikanond, W; Eroglu, E; Klec, C; Waldeck-Weiermair, M; Malli, R; Graier, WF Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria.
Cell Physiol Biochem. 2016; 39(4):1404-1420 [OPEN ACCESS]
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Scheipl, S; Barnard, M; Cottone, L; Jorgensen, M; Drewry, DH; Zuercher, WJ; Turlais, F; Ye, H; Leite, AP; Smith, JA; Leithner, A; Möller, P; Brüderlein, S; Guppy, N; Amary, F; Tirabosco, R; Strauss, SJ; Pillay, N; Flanagan, AM EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen.
J Pathol. 2016; 239(3):320-334 [OPEN ACCESS]
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Schneider, S; Thurnher, D; Kadletz, L; Seemann, R; Brunner, M; Kotowski, U; Schmid, R; Lill, C; Heiduschka, G Effects of neratinib and combination with irradiation and chemotherapy in head and neck cancer cells.
Oral Dis. 2016; 22(8):797-804
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Vogl, F; Humpolickova, J; Amaro, M; Koller, D; Kofeler, H; Zenzmaier, E; Hof, M; Hermetter, A Role of protein kinase C delta in apoptotic signaling of oxidized phospholipids in RAW 264.7 macrophages
BBA-MOL CELL BIOL L. 2016; 1861(4): 320-330.
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2015

Aguiriano-Moser, V; Svejda, B; Li, ZX; Sturm, S; Stuppner, H; Ingolic, E; Höger, H; Siegl, V; Meier-Allard, N; Sadjak, A; Pfragner, R Ursolic acid from Trailliaedoxa gracilis induces apoptosis in medullary thyroid carcinoma cells.
Mol Med Rep. 2015; 12(4):5003-5011 [OPEN ACCESS]
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Dehghan Esmatabadi, MJ; Farhangi, B; Safari, Z; Kazerooni, H; Shirzad, H; Zolghadr, F; Sadeghizadeh, M Dendrosomal curcumin inhibits metastatic potential of human SW480 colon cancer cells through Down-regulation of Claudin1, Zeb1 and Hef1-1 gene expression.
Asian Pac J Cancer Prev. 2015; 16(6):2473-2481 [OPEN ACCESS]
PubMed

 

Fischer, C; Leithner, K; Wohlkoenig, C; Quehenberger, F; Bertsch, A; Olschewski, A; Olschewski, H; Hrzenjak, A Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization.
Mol Cancer. 2015; 14(8):4-4 [OPEN ACCESS]
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Fisser, MC; Rommer, A; Steinleitner, K; Heller, G; Herbst, F; Wiese, M; Glimm, H; Sill, H; Wieser, R Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.
Mol Carcinog. 2015; 54(12):1815-1819 [OPEN ACCESS]
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Froehlich, EV; Rinner, B; Deutsch, AJ; Meditz, K; Knausz, H; Troppan, K; Scheipl, S; Wibmer, C; Leithner, A; Liegl, B; Lohberger, B Examination of survivin expression in 50 chordoma specimens--A histological and in vitro study.
J Orthop Res. 2015; 33(5):771-778 [OPEN ACCESS]
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Fuchs, R; Schwach, G; Stracke, A; Meier-Allard, N; Absenger, M; Ingolic, E; Haas, HS; Pfragner, R; Sadjak, A The anti-hypertensive drug prazosin induces apoptosis in the medullary thyroid carcinoma cell line TT.
Anticancer Res. 2015; 35(1):31-38 [OPEN ACCESS]
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Fuchs, R; Stracke, A; Ebner, N; Zeller, CW; Raninger, AM; Schittmayer, M; Kueznik, T; Absenger-Novak, M; Birner-Gruenberger, R The cytotoxicity of the α1-adrenoceptor antagonist prazosin is linked to an endocytotic mechanism equivalent to transport-P.
Toxicology. 2015; 338(6):17-29 [OPEN ACCESS]
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Haymerle, G; Thurnher, D; Kadletz, L; Stanisz, I; Brunner, M; Kotowski, U; Enzenhofer, E; Heiduschka, G Assessment of caroverine as a potential chemotherapeutical agent in HNSCC cell lines.
Eur Arch Otorhinolaryngol. 2015; 272(11):3451-3456
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Lohberger, B; Kretschmer, N; Bernhart, E; Rinner, B; Stuendl, N; Kaltenegger, H; Kahl, S; Bauer, R; Leithner, A 25-O-acetyl-23,24-dihydro-cucurbitacin F induces cell cycle G2/M arrest and apoptosis in human soft tissue sarcoma cells.
J Ethnopharmacol. 2015; 164(36):265-272
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Lohberger, B; Leithner, A; Stuendl, N; Kaltenegger, H; Kullich, W; Steinecker-Frohnwieser, B Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation.
BMC Cancer. 2015; 15(3):891-891 [OPEN ACCESS]
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Mangmool, S; Hemplueksa, P; Parichatikanond, W; Chattipakorn, N Epac is required for GLP-1R-mediated inhibition of oxidative stress and apoptosis in cardiomyocytes.
Mol Endocrinol. 2015; 29(4): 583-596. [OPEN ACCESS]
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Mayr, C; Neureiter, D; Pichler, M; Berr, F; Wagner, A; Kiesslich, T; Namberger, K Cytotoxic effects of chemokine receptor 4 inhibition by AMD3100 in biliary tract cancer cells: Potential drug synergism with gemcitabine.
Mol Med Rep. 2015; 12(2):2247-2252 [OPEN ACCESS]
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Mayr, C; Wagner, A; Neureiter, D; Pichler, M; Jakab, M; Illig, R; Berr, F; Kiesslich, T The green tea catechin epigallocatechin gallate induces cell cycle arrest and shows potential synergism with cisplatin in biliary tract cancer cells.
BMC Complement Altern Med. 2015; 15(6):194-194 [OPEN ACCESS]
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Meindl, C; Kueznik, T; Bösch, M; Roblegg, E; Fröhlich, E Intracellular calcium levels as screening tool for nanoparticle toxicity.
J Appl Toxicol. 2015; 35(10):1150-1159 [OPEN ACCESS]
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Ramprecht, C; Jaritz, H; Streith, I; Zenzmaier, E; Köfeler, H; Hofmann-Wellenhof, R; Schaider, H; Hermetter, A Toxicity of oxidized phosphatidylcholines in cultured human melanoma cells.
Chem Phys Lipids. 2015; 189(136):39-47
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Riedl, S; Leber, R; Rinner, B; Schaider, H; Lohner, K; Zweytick, D Human lactoferricin derived di-peptides deploying loop structures induce apoptosis specifically in cancer cells through targeting membranous phosphatidylserine.
Biochim Biophys Acta. 2015; 1848(11 Pt A):2918-2931 [OPEN ACCESS]
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2014

Forster, T; Rausch, V; Zhang, Y; Isayev, O; Heilmann, K; Schoensiegel, F; Liu, L; Nessling, M; Richter, K; Labsch, S; Nwaeburu, CC; Mattern, J; Gladkich, J; Giese, N; Werner, J; Schemmer, P; Gross, W; Gebhard, MM; Gerhauser, C; Schaefer, M; Herr, I Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication.
Oncotarget. 2014; 5(6):1621-1634 [OPEN ACCESS]
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Fröhlich, E; Meindl, C; Wagner, K; Leitinger, G; Roblegg, E Use of whole genome expression analysis in the toxicity screening of nanoparticles.
Toxicol Appl Pharmacol. 2014; 280(2):272-284 [OPEN ACCESS]
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Heiduschka, G; Bigenzahn, J; Brunner, M; Thurnher, D Resveratrol synergistically enhances the effect of etoposide in HNSCC cell lines.
Acta Otolaryngol. 2014; 134(10): 1071-1078.
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Heiduschka, G; Lill, C; Schneider, S; Seemann, R; Kornek, G; Schmid, R; Kotowski, U; Thurnher, D The effect of cilengitide in combination with irradiation and chemotherapy in head and neck squamous cell carcinoma cell lines.
Strahlenther Onkol. 2014; 190(5): 472-479.
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Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12):2393-2403 [OPEN ACCESS]
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Kiesslich, T; Mayr, C; Wachter, J; Bach, D; Fuereder, J; Wagner, A; Alinger, B; Pichler, M; Di Fazio, P; Ocker, M; Berr, F; Neureiter, D Activated hedgehog pathway is a potential target for pharmacological intervention in biliary tract cancer.
Mol Cell Biochem. 2014; 396(1-2):257-268
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Koyani, CN; Windischhofer, W; Rossmann, C; Jin, G; Kickmaier, S; Heinzel, FR; Groschner, K; Alavian-Ghavanini, A; Sattler, W; Malle, E 15-deoxy-Δ¹²,¹⁴-PGJ₂ promotes inflammation and apoptosis in cardiomyocytes via the DP2/MAPK/TNFα axis.
Int J Cardiol. 2014; 173(3):472-480 [OPEN ACCESS]
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Quan, P; Moinfar, F; Kufferath, I; Absenger, M; Kueznik, T; Denk, H; Zatloukal, K; Haybaeck, J Effects of targeting endometrial stromal sarcoma cells via histone deacetylase and PI3K/AKT/mTOR signaling.
Anticancer Res. 2014; 34(6):2883-2897
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Schelch, K; Hoda, MA; Klikovits, T; Münzker, J; Ghanim, B; Wagner, C; Garay, T; Laszlo, V; Setinek, U; Dome, B; Filipits, M; Pirker, C; Heffeter, P; Selzer, E; Tovari, J; Torok, S; Kenessey, I; Holzmann, K; Grasl-Kraupp, B; Marian, B; Klepetko, W; Berger, W; Hegedus, B; Grusch, M Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.
Am J Respir Crit Care Med. 2014; 190(7):763-772
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Schneditz, G; Rentner, J; Roier, S; Pletz, J; Herzog, KA; Bücker, R; Troeger, H; Schild, S; Weber, H; Breinbauer, R; Gorkiewicz, G; Högenauer, C; Zechner, EL Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis.
Proc Natl Acad Sci U S A. 2014; 111(36):13181-13186 [OPEN ACCESS]
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Veith, C; Zakrzewicz, D; Dahal, BK; Bálint, Z; Murmann, K; Wygrecka, M; Seeger, W; Schermuly, RT; Weissmann, N; Kwapiszewska, G Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.
Thromb Haemost. 2014; 112(6):1288-1303
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2013

Carmona-Gutierrez, D; Alavian-Ghavanini, A; Habernig, L; Bauer, MA; Hammer, A; Rossmann, C; Zimmermann, AS; Ruckenstuhl, C; Büttner, S; Eisenberg, T; Sattler, W; Malle, E; Madeo, F The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast.
Cell Cycle. 2013; 12(11):1704-1712 [OPEN ACCESS]
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Cekauskas, A; Bruns, H; Manikas, M; Herr, I; Gross, ML; Zorn, M; Jankevicius, F; Strupas, K; Schemmer, P Sulforaphane decreases kidney injury after transplantation in rats: role of mitochondrial damage.
Ann Transplant. 2013; 18(3-4):488-496 [OPEN ACCESS]
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Fröhlich, E; Meindl, C; Höfler, A; Leitinger, G; Roblegg, E Combination of small size and carboxyl functionalisation causes cytotoxicity of short carbon nanotubes.
Nanotoxicology. 2013; 7(7):1211-1224 [OPEN ACCESS]
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Glehr, M; Fritsch-Breisach, M; Lohberger, B; Walzer, SM; Moazedi-Fuerst, F; Rinner, B; Gruber, G; Graninger, W; Leithner, A; Windhager, R Influence of resveratrol on rheumatoid fibroblast-like synoviocytes analysed with gene chip transcription.
Phytomedicine. 2013; 20(3-4):310-318
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Halasiddappa, LM; Koefeler, H; Futerman, AH; Hermetter, A Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases.
PLoS One. 2013; 8(7):e70002-e70002 [OPEN ACCESS]
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Hofer, D; Schwach, G; Ghaffari Tabrizi-Wizsy, N; Sadjak, A; Sturm, S; Stuppner, H; Pfragner, R Christia vespertilionis plant extracts as novel antiproliferative agent against human neuroendocrine tumor cells.
Oncol Rep. 2013; 29(6):2219-2226 [OPEN ACCESS]
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Kargl, J; Haybaeck, J; Stančić, A; Andersen, L; Marsche, G; Heinemann, A; Schicho, R O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms.
J Mol Med (Berl). 2013; 91(4):449-458 [OPEN ACCESS]
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Menon, DR; Wels, C; Bonyadi Rad, E; Joshi, S; Knausz, H; Lade-Keller, J; Brandner, JM; Schaider, H TGF-β1 and TNF-α differentially regulate Twist1 mediated resistance towards BRAF/MEK inhibition in melanoma.
Pigment Cell Melanoma Res. 2013; 26(6):912-916
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