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Publikationen

Suchbegriffe: APOB, . Treffer: 106

2022

Degoricija, V; Klobučar, I; Potočnjak, I; Dokoza, Terešak, S; Vidović, L; Pregartner, G; Berghold, A; Habisch, H; Madl, T; Frank, S Cholesterol Content of Very-Low-Density Lipoproteins Is Associated with 1-Year Mortality in Acute Heart Failure Patients.
BIOMOLECULES. 2022; 12(10): Doi: 10.3390/biom12101542 [OPEN ACCESS]
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Holzer, M; Ljubojevic-Holzer, S; Souza, Junior, DR; Stadler, JT; Rani, A; Scharnagl, H; Ronsein, GE; Marsche, G HDL Isolated by Immunoaffinity, Ultracentrifugation, or Precipitation is Compositionally and Functionally Distinct.
J Lipid Res. 2022; 63(12):100307 Doi: 10.1016/j.jlr.2022.100307 [OPEN ACCESS]
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Marchini, T; Malchow, S; Caceres, L; El Rabih, AA; Hansen, S; Mwinyella, T; Spiga, L; Piepenburg, S; Horstmann, H; Olawale, T; Li, XW; Mitre, LS; Gissler, MC; Bugger, H; Zirlik, A; Heidt, T; Hilgendorf, I; Stachon, P; Muehlen, CV; Bode, C; Wolf, D Circulating Autoantibodies Recognizing Immunodominant Epitopes From Human Apolipoprotein B Associate With Cardiometabolic Risk Factors, but Not With Atherosclerotic Disease
FRONT CARDIOVASC MED. 2022; 9: 826729 Doi: 10.3389/fcvm.2022.826729 [OPEN ACCESS]
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Pott, J; Gådin, JR; Theusch, E; Kleber, ME; Delgado, GE; Kirsten, H; Hauck, SM; Burkhardt, R; Scharnagl, H; Krauss, RM; Loeffler, M; März, W; Thiery, J; Silveira, A; Van't, Hooft, FM; Scholz, M Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2.
Hum Mol Genet. 2022; 31(6):999-1011 Doi: 10.1093/hmg/ddab279 [OPEN ACCESS]
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Silbernagel, G; Scharnagl, H; Saely, CH; Reinthaler, M; Rief, M; Kleber, ME; Larcher, B; Chapman, J; Schaefer, JR; Drexel, H; März, W The LDL Apolipoprotein B-to-LDL Cholesterol Ratio: Association with Cardiovascular Mortality and a Biomarker of Small, Dense LDLs.
Biomedicines. 2022; 10(6): 1302 Doi: 10.3390/biomedicines10061302 [OPEN ACCESS]
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Stadler, JT; Lackner, S; Mörkl, S; Meier-Allard, N; Scharnagl, H; Rani, A; Mangge, H; Zelzer, S; Holasek, SJ; Marsche, G Anorexia Nervosa Is Associated with a Shift to Pro-Atherogenic Low-Density Lipoprotein Subclasses.
Biomedicines. 2022; 10(4): Doi: 10.3390/biomedicines10040895 [OPEN ACCESS]
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Stadler, JT; Mangge, H; Rani, A; Curcic, P; Herrmann, M; Prüller, F; Marsche, G Low HDL Cholesterol Efflux Capacity Indicates a Fatal Course of COVID-19.
Antioxidants (Basel). 2022; 11(10): Doi: 10.3390/antiox11101858 [OPEN ACCESS]
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2021

Fallah, S; Marsche, G; Mohamadinarab, M; Mohassel Azadi, S; Ghasri, H; Fadaei, R; Moradi, N Impaired cholesterol efflux capacity in patients with Helicobacter pylori infection and its relation with inflammation.
J Clin Lipidol. 2020; 15(1):218-226 Doi: 10.1016/j.jacl.2020.11.005
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2020

Leskelä, J; Pietiäinen, M; Safer, A; Lehto, M; Metso, J; Malle, E; Buggle, F; Becher, H; Sundvall, J; Grau, AJ; Pussinen, PJ; Palm, F Serum lipopolysaccharide neutralizing capacity in ischemic stroke.
PLoS One. 2020; 15(2): e0228806-e0228806. Doi: 10.1371/journal.pone.0228806 [OPEN ACCESS]
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Ritsch, A; Duerr, A; Kahler, P; Hunjadi, M; Stojakovic, T; Silbernagel, G; Scharnagl, H; Kleber, ME; März, W Cholesterol Efflux Capacity and Cardiovascular Disease: The Ludwigshafen Risk and Cardiovascular Health (LURIC) Study.
Biomedicines. 2020; 8(11): Doi: 10.3390/biomedicines8110524 [OPEN ACCESS]
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Silbernagel, G; Scharnagl, H; Kleber, ME; Hoffmann, MM; Delgado, G; Stojakovic, T; Gary, T; Zeng, L; Ritsch, A; Zewinger, S; Speer, T; Schunkert, H; Landmesser, U; März, W; Grammer, TB, ;Meta-Analyses, of, Glucose, and, Insulin-related, traits, Consortium, (MAGIC);Meta-Analyses, of, Glucose, and, Insulin-related, traits, Consortium, (MAGIC) Common APOC3 variants are associated with circulating ApoC-III and VLDL cholesterol but not with total apolipoprotein B and coronary artery disease.
Atherosclerosis. 2020; 311:84-90 Doi: 10.1016/j.atherosclerosis.2020.08.017
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Vujić, N; Korbelius, M; Sachdev, V; Rainer, S; Zimmer, A; Huber, A; Radović, B; Kratky, D Intestine-specific DGAT1 deficiency improves atherosclerosis in apolipoprotein E knockout mice by reducing systemic cholesterol burden.
Atherosclerosis. 2020; 310:26-36 Doi: 10.1016/j.atherosclerosis.2020.07.030 [OPEN ACCESS]
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Wolf, D; Gerhardt, T; Winkels, H; Michel, NA; Pramod, AB; Ghosheh, Y; Brunel, S; Buscher, K; Miller, J; McArdle, S; Baas, L; Kobiyama, K; Vassallo, M; Ehinger, E; Dileepan, T; Ali, A; Schell, M; Mikulski, Z; Sidler, D; Kimura, T; Sheng, X; Horstmann, H; Hansen, S; Mitre, LS; Stachon, P; Hilgendorf, I; Gaddis, DE; Hedrick, C; Benedict, CA; Peters, B; Zirlik, A; Sette, A; Ley, K Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B₁₀₀-Reactive CD4⁺ T-Regulatory Cells.
Circulation. 2020; 142(13):1279-1293 Doi: 10.1161/CIRCULATIONAHA.119.042863 [OPEN ACCESS]
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2019

Blom, WAM; Koppenol, WP; Hiemstra, H; Stojakovic, T; Scharnagl, H; Trautwein, EA A low-fat spread with added plant sterols and fish omega-3 fatty acids lowers serum triglyceride and LDL-cholesterol concentrations in individuals with modest hypercholesterolaemia and hypertriglyceridaemia.
Eur J Nutr. 2019; 58(4):1615-1624 Doi: 10.1007/s00394-018-1706-1 [OPEN ACCESS]
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Hollstein, T; Vogt, A; Grenkowitz, T; Stojakovic, T; März, W; Laufs, U; Bölükbasi, B; Steinhagen-Thiessen, E; Scharnagl, H; Kassner, U Treatment with PCSK9 inhibitors reduces atherogenic VLDL remnants in a real-world study.
Vascul Pharmacol. 2019; 116:8-15 Doi: 10.1016/j.vph.2019.03.002
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Trakaki, A; Sturm, GJ; Pregartner, G; Scharnagl, H; Eichmann, TO; Trieb, M; Knuplez, E; Holzer, M; Stadler, JT; Heinemann, A; Sturm, EM; Marsche, G Allergic rhinitis is associated with complex alterations in high-density lipoprotein composition and function.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(10):1280-1292 Doi: 10.1016/j.bbalip.2019.06.007 [OPEN ACCESS]
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Trieb, M; Kornej, J; Knuplez, E; Hindricks, G; Thiele, H; Sommer, P; Scharnagl, H; Dagres, N; Dinov, B; Bollmann, A; Husser, D; Marsche, G; Buettner, P Atrial fibrillation is associated with alterations in HDL function, metabolism, and particle number.
Basic Res Cardiol. 2019; 114(4): 27-27. Doi: 10.1007/s00395-019-0735-0
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2018

Contreras-Duarte, S; Chen, P; Andía, M; Uribe, S; Irarrázaval, P; Kopp, S; Kern, S; Marsche, G; Busso, D; Wadsack, C; Rigotti, A Attenuation of atherogenic apo B-48-dependent hyperlipidemia and high density lipoprotein remodeling induced by vitamin C and E combination and their beneficial effect on lethal ischemic heart disease in mice.
Biol Res. 2018; 51(1): 34-34. Doi: 10.1186/s40659-018-0183-6 [OPEN ACCESS]
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Dieberger, AM; de Rooij, SR; Korosi, A; Vrijkotte, TGM Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring.
Nutrients. 2018; 10(8): Doi: 10.3390/nu10081026 [OPEN ACCESS]
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Lindquist, C; Bjørndal, B; Rossmann, CR; Svardal, A; Hallström, S; Berge, RK A fatty acid analogue targeting mitochondria exerts a plasma triacylglycerol lowering effect in rats with impaired carnitine biosynthesis.
PLoS One. 2018; 13(3): e0194978-e0194978. Doi: 10.1371/journal.pone.0194978 [OPEN ACCESS]
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Schwetz, V; Scharnagl, H; Trummer, C; Stojakovic, T; Pandis, M; Grübler, MR; Verheyen, N; Gaksch, M; Zittermann, A; Aberer, F; Lerchbaum, E; Obermayer-Pietsch, B; Pieber, TR; März, W; Tomaschitz, A; Pilz, S Vitamin D supplementation and lipoprotein metabolism: A randomized controlled trial.
J Clin Lipidol. 2018; 12(3):588-596.e4 Doi: 10.1016/j.jacl.2018.03.079
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Untersteller, K; Meissl, S; Trieb, M; Emrich, IE; Zawada, AM; Holzer, M; Knuplez, E; Fliser, D; Heine, GH; Marsche, G HDL functionality and cardiovascular outcome among nondialysis chronic kidney disease patients.
J Lipid Res. 2018; 59(7):1256-1265 Doi: 10.1194/jlr.P085076 [OPEN ACCESS]
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2017

März, W; Grammer, TB; Delgado, G; Kleber, ME [Congenital disorders of lipoprotein metabolism].
Herz. 2017; 42(5):449-458 Doi: 10.1007/s00059-017-4578-x [OPEN ACCESS]
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Peters, J; Martinez, N; Lehofer, B; Prassl, R Low-density lipoproteins investigated under high hydrostatic pressure by elastic incoherent neutron scattering.
Eur Phys J E Soft Matter. 2017; 40(7):68-68 Doi: 10.1140/epje/i2017-11558-8 [OPEN ACCESS]
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Schaefermeier, P; Heinze, S Hippocampal Characteristics and Invariant Sequence Elements Distribution of GLRA2 and GLRA3 C-to-U Editing.
Mol Syndromol. 2017; 8(2):85-92 Doi: 10.1159/000453300 [OPEN ACCESS]
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2016

Grenkowitz, T; Kassner, U; Wühle-Demuth, M; Salewsky, B; Rosada, A; Zemojtel, T; Hopfenmüller, W; Isermann, B; Borucki, K; Heigl, F; Laufs, U; Wagner, S; Kleber, ME; Binner, P; März, W; Steinhagen-Thiessen, E; Demuth, I Clinical characterization and mutation spectrum of German patients with familial hypercholesterolemia.
Atherosclerosis. 2016; 253(19-20):88-93 Doi: 10.1016/j.atherosclerosis.2016.08.037
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Hörl, G; Froehlich, H; Ferstl, U; Ledinski, G; Binder, J; Cvirn, G; Stojakovic, T; Trauner, M; Koidl, C; Tafeit, E; Amrein, K; Scharnagl, H; Jürgens, G; Hallström, S Simvastatin Efficiently Lowers Small LDL-IgG Immune Complex Levels: A Therapeutic Quality beyond the Lipid-Lowering Effect.
PLoS One. 2016; 11(2):e0148210-e0148210 Doi: 10.1371/journal.pone.0148210 [OPEN ACCESS]
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Löffler, T; Schweinzer, C; Flunkert, S; Sántha, M; Windisch, M; Steyrer, E; Hutter-Paier, B Brain cortical cholesterol metabolism is highly affected by human APP overexpression in mice.
Mol Cell Neurosci. 2016; 74(2):34-41 Doi: 10.1016/j.mcn.2016.03.004
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Pertl, L; Kern, S; Weger, M; Hausberger, S; Trieb, M; Gasser-Steiner, V; Haas, A; Scharnagl, H; Heinemann, A; Marsche, G High-Density Lipoprotein Function in Exudative Age-Related Macular Degeneration.
PLoS One. 2016; 11(5):e0154397-e0154397 Doi: 10.1371/journal.pone.0154397 [OPEN ACCESS]
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Potočnjak, I; Degoricija, V; Trbušić, M; Terešak, SD; Radulović, B; Pregartner, G; Berghold, A; Tiran, B; Marsche, G; Frank, S Metrics of High-Density Lipoprotein Function and Hospital Mortality in Acute Heart Failure Patients.
PLoS One. 2016; 11(6):e0157507-e0157507 Doi: 10.1371/journal.pone.0157507 [OPEN ACCESS]
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Trieb, M; Horvath, A; Birner-Gruenberger, R; Spindelboeck, W; Stadlbauer, V; Taschler, U; Curcic, S; Stauber, RE; Holzer, M; Pasterk, L; Heinemann, A; Marsche, G Liver disease alters high-density lipoprotein composition, metabolism and function.
Biochim Biophys Acta. 2016; 1861(7):630-638 Doi: 10.1016/j.bbalip.2016.04.013 [OPEN ACCESS]
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2015

UK10K Consortium; Walter, K; Min, JL; Huang, J; Crooks, L; Memari, Y; McCarthy, S; Perry, JR; Xu, C; Futema, M; Lawson, D; Iotchkova, V; Schiffels, S; Hendricks, AE; Danecek, P; Li, R; Floyd, J; Wain, LV; Barroso, I; Humphries, SE; Hurles, ME; Zeggini, E; Barrett, JC; Plagnol, V; Richards, JB; Greenwood, CM; Timpson, NJ; Durbin, R; Soranzo, N The UK10K project identifies rare variants in health and disease.
Nature. 2015; 526(7571):82-90 Doi: 10.1038/nature14962 [OPEN ACCESS]
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2014

Delporte, C; Boudjeltia, KZ; Noyon, C; Furtmüller, PG; Nuyens, V; Slomianny, MC; Madhoun, P; Desmet, JM; Raynal, P; Dufour, D; Koyani, CN; Reyé, F; Rousseau, A; Vanhaeverbeek, M; Ducobu, J; Michalski, JC; Nève, J; Vanhamme, L; Obinger, C; Malle, E; Van Antwerpen, P Impact of myeloperoxidase-LDL interactions on enzyme activity and subsequent posttranslational oxidative modifications of apoB-100.
J Lipid Res. 2014; 55(4):747-757 Doi: 10.1194/jlr.M047449 [OPEN ACCESS]
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Hörl, G; Ledinski, G; Kager, G; Hallström, S; Tafeit, E; Koestenberger, M; Jürgens, G; Cvirn, G In vitro oxidation of LDL by ozone.
Chem Phys Lipids. 2014; 183(7):18-21 Doi: 10.1016/j.chemphyslip.2014.05.002
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2013

Bauer, R; Plieschnig, JA; Finkes, T; Riegler, B; Hermann, M; Schneider, WJ The developing chicken yolk sac acquires nutrient transport competence by an orchestrated differentiation process of its endodermal epithelial cells.
J Biol Chem. 2013; 288(2): 1088-1098. Doi: 10.1074/jbc.M112.393090 [OPEN ACCESS]
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Gautier, T; de Haan, W; Grober, J; Ye, D; Bahr, MJ; Claudel, T; Nijstad, N; Van Berkel, TJ; Havekes, LM; Manns, MP; Willems, SM; Hogendoorn, PC; Lagrost, L; Kuipers, F; Van Eck, M; Rensen, PC; Tietge, UJ Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice.
J Lipid Res. 2013; 54(8):2195-2205 Doi: 10.1194/jlr.M038141 [OPEN ACCESS]
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Kostner, KM; März, W; Kostner, GM When should we measure lipoprotein (a)?
Eur Heart J. 2013; 34(42):3268-3276 Doi: 10.1093/eurheartj/eht053 [OPEN ACCESS]
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Löffler, T; Flunkert, S; Havas, D; Sántha, M; Hutter-Paier, B; Steyrer, E; Windisch, M Impact of ApoB-100 expression on cognition and brain pathology in wild-type and hAPPsl mice.
Neurobiol Aging. 2013; 34(10):2379-2388 Doi: 10.1016/j.neurobiolaging.2013.04.008
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2011

Mikl, C; Peters, J; Trapp, M; Kornmueller, K; Schneider, WJ; Prassl, R Softness of Atherogenic Lipoproteins: A Comparison of Very Low Density Lipoprotein (VLDL) and Low Density Lipoprotein (LDL) Using Elastic Incoherent Neutron Scattering (EINS)
J Am Chem Soc. 2011; 133(34):13213-13215 Doi: 10.1021/ja203679g [OPEN ACCESS]
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2009

Prassl, R; Laggner, P Molecular structure of low density lipoprotein: current status and future challenges
Eur Biophys J. 2009; 38(2):145-158 Doi: 10.1007/s00249-008-0368-y
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2007

Scharnagl, H; Stojakovic, T; Winkler, K; Rosinger, S; März, W; Boehm, BO The HMG-CoA reductase inhibitor cerivastatin lowers advanced glycation end products in patients with type 2 diabetes.
EXP CLIN ENDOCRINOL DIABETES. 2007; 115(6): 372-375. Doi: 10.1055/s-2007-973830
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Sundl, I; Guardiola, M; Khoschsorur, G; Solà, R; Vallvé, JC; Godàs, G; Masana, L; Maritschnegg, M; Meinitzer, A; Cardinault, N; Roob, JM; Rock, E; Winklhofer-Roob, BM; Ribalta, J Increased concentrations of circulating vitamin E in carriers of the apolipoprotein A5 gene - 1131T>C variant and associations with plasma lipids and lipid peroxidation.
J LIPID RES. 2007; 48(11): 2506-2513. Doi: 10.1194/jlr.M700285-JLR200 [OPEN ACCESS]
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Widhalm, K; Dirisamer, A; Lindemayr, A; Kostner, G Diagnosis of families with familial hypercholesterolaemia and/or Apo B-100 defect by means of DNA analysis of LDL-receptor gene mutations.
J Inherit Metab Dis. 2007; 30(2): 239-247. Doi: 10.1007/s10545-007-0563-5
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2006

Johs, A; Hammel, M; Waldner, I; May, RP; Laggner, P; Prassl, R Modular structure of solubilized human apolipoprotein B-100 - Low resolution model revealed by small angle neutron scattering
J Biol Chem. 2006; 281(28):19732-19739 Doi: 10.1074/jbc.M601688200 [OPEN ACCESS]
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Krisko, A; Piantanida, I; Kveder, M; Pifat, G; Lee, A; Greilberger, J; Kipmen-Korgun, D; Jürgens, G The effect of heparin on structural and functional properties of low density lipoproteins.
BIOPHYS CHEM. 2006; 119(3): 234-239. Doi: 10.1016/j.bpc.2005.09.011
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2005

Tancevski, I; Frank, S; Massoner, P; Stanzl, U; Schgoer, W; Wehinger, A; Fievet, C; Eller, P; Patsch, JR; Ritsch, A Increased plasma levels of LDL cholesterol in rabbits after adenoviral overexpression of human scavenger receptor class B type I.
J MOL MED-JMM. 2005; 83(11): 927-932. Doi: 10.1007/s00109-005-0695-8
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2004

März, W; Scharnagl, H; Hoffmann, MM; Boehm, BO; Winkelmann, BR The apolipoprotein E polymorphism is associated with circulating C-reactive protein (the Ludwigshafen risk and cardiovascular health study).
Eur Heart J. 2004; 25(23):2109-2119 Doi: 10.1016/j.ehj.2004.08.024 [OPEN ACCESS]
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Soufi, M; Sattler, AM; Maerz, W; Starke, A; Herzum, M; Maisch, B; Schaefer, JR A new but frequent mutation of apoB-100-apoB His3543Tyr.
Atherosclerosis. 2004; 174(1):11-16 Doi: 10.1016/j.atherosclerosis.2003.12.021
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Wetzka, B; Hoffmann, MM; Friedrich, I; Baumstark, MW; Zahradnik, HP; März, W; Winkler, K Transient remnant removal disease in acute fatty liver of pregnancy.
Hypertens Pregnancy. 2004; 23(2):143-153 Doi: 10.1081/PRG-120028290 (- Case Report)
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Winkler, K; Abletshauser, C; Friedrich, I; Hoffmann, MM; Wieland, H; März, W Fluvastatin slow-release lowers platelet-activating factor acetyl hydrolase activity: a placebo-controlled trial in patients with type 2 diabetes.
J Clin Endocrinol Metab. 2004; 89(3):1153-1159 Doi: 10.1210/jc.2003-031494 [OPEN ACCESS]
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