Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: ANTINEOPLASTIC AGENTS - PHARMACOLOGY , . Treffer: 89

2018

Alvarez, MJ; Subramaniam, PS; Tang, LH; Grunn, A; Aburi, M; Rieckhof, G; Komissarova, EV; Hagan, EA; Bodei, L; Clemons, PA; Dela Cruz, FS; Dhall, D; Diolaiti, D; Fraker, DA; Ghavami, A; Kaemmerer, D; Karan, C; Kidd, M; Kim, KM; Kim, HC; Kunju, LP; Langel, U; Li, Z; Lee, J; Li, H; LiVolsi, V; Pfragner, R; Schwach, G; Rainey, AR; Realubit, RB; Remotti, H; Regberg, J; Roses, R; Rustgi, A; Sepulveda, AR; Serra, S; Shi, CJ; Yuan, XP; Barberis, M; Bergamaschi, R; Chinnaiyan, AM; Detre, T; Ezzat, S; Frilling, A; Hommann, M; Jaeger, D; Kim, MK; Knudsen, BS; Kung, AL; Leahy, E; Metz, DC; Milsom, JW; Park, YS; Reidy-Lagunes, D; Schreiber, S; Washington, K; Wiedenmann, B; Modlin, I; Califano, A A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors.
Nat Genet. 2018; 50(7):979-989 [OPEN ACCESS]
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Li, M; Zhang, F; Su, Y; Zhou, J; Wang, W Nanoparticles designed to regulate tumor microenvironment for cancer therapy.
Life Sci. 2018; 201: 37-44.
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Mohsin, NU; Seebacher, W; Faist, J; Hochegger, P; Kaiser, M; Mäser, P; Belaj, F; Saf, R; Kretschmer, N; Alajlani, M; Turek, I; Brantner, A; Bauer, R; Bucar, F; Weis, R Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities.
Eur J Med Chem. 2018; 143(8):97-106
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Mutgan, AC; Besikcioglu, HE; Wang, S; Friess, H; Ceyhan, GO; Demir, IE Insulin/IGF-driven cancer cell-stroma crosstalk as a novel therapeutic target in pancreatic cancer.
Mol Cancer. 2018; 17(1): 66-66. [OPEN ACCESS]
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Presser, A; Lainer, G; Kretschmer, N; Schuehly, W; Saf, R; Kaiser, M; Kalt, MM Synthesis of Jacaranone-Derived Nitrogenous Cyclohexadienones and Their Antiproliferative and Antiprotozoal Activities.
Molecules. 2018; 23(11): [OPEN ACCESS]
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2017

Enzenhofer, E; Kadletz, L; Stanisz, I; Kotowski, U; Seemann, R; Schmid, R; Thurnher, D; Heiduschka, G Effect of the histone deacetylase inhibitor resminostat on head and neck squamous cell carcinoma cell lines.
Head Neck. 2017; 39(5):900-907
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Lohberger, B; Stuendl, N; Leithner, A; Rinner, B; Sauer, S; Kashofer, K; Liegl-Atzwanger, B Establishment of a novel cellular model for myxofibrosarcoma heterogeneity.
Sci Rep. 2017; 7(9):44700-44700 [OPEN ACCESS]
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Madreiter-Sokolowski, CT; Sokolowski, AA; Graier, WF Dosis Facit Sanitatem-Concentration-Dependent Effects of Resveratrol on Mitochondria.
Nutrients. 2017; 9(10): [OPEN ACCESS]
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Schanza, LM; Seles, M; Stotz, M; Fosselteder, J; Hutterer, GC; Pichler, M; Stiegelbauer, V MicroRNAs Associated with Von Hippel-Lindau Pathway in Renal Cell Carcinoma: A Comprehensive Review.
Int J Mol Sci. 2017; 18(11): [OPEN ACCESS]
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Wallner, M; Khafaga, M; Kolesnik, E; Vafiadis, A; Schwantzer, G; Eaton, DM; Curcic, P; Köstenberger, M; Knez, I; Rainer, PP; Pichler, M; Pieske, B; Lewinski, DV Istaroxime, a potential anticancer drug in prostate cancer, exerts beneficial functional effects in healthy and diseased human myocardium.
Oncotarget. 2017; 8(30):49264-49274 [OPEN ACCESS]
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2016

Arriga, R; Caratelli, S; Coppola, A; Spagnoli, GC; Venditti, A; Amadori, S; Lanzilli, G; Lauro, D; Palomba, P; Sconocchia, T; Del Principe, MI; Maurillo, L; Buccisano, F; Capuani, B; Ferrone, S; Sconocchia, G Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage.
Oncotarget. 2016; 7(2): 2070-2079. [OPEN ACCESS]
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Fan, P; Zhang, Y; Liu, L; Zhao, Z; Yin, Y; Xiao, X; Bauer, N; Gladkich, J; Mattern, J; Gao, C; Schemmer, P; Gross, W; Herr, I Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.
Cell Death Dis. 2016; 7(6):e2246-e2246 [OPEN ACCESS]
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He, JC; Yao, W; Wang, JM; Schemmer, P; Yang, Y; Liu, Y; Qian, YW; Qi, WP; Zhang, J; Shen, Q; Yang, T TACC3 overexpression in cholangiocarcinoma correlates with poor prognosis and is a potential anti-cancer molecular drug target for HDAC inhibitors.
Oncotarget. 2016; 7(46):75441-75456 [OPEN ACCESS]
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Mayr, C; Wagner, A; Loeffelberger, M; Bruckner, D; Jakab, M; Berr, F; Di Fazio, P; Ocker, M; Neureiter, D; Pichler, M; Kiesslich, T The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells.
Oncotarget. 2016; 7(1):745-758 [OPEN ACCESS]
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Pacifico, S; Piccolella, S; Galasso, S; Fiorentino, A; Kretschmer, N; Pan, SP; Bauer, R; Monaco, P Influence of harvest season on chemical composition and bioactivity of wild rue plant hydroalcoholic extracts.
Food Chem Toxicol. 2016; 90(2):102-111
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Perakis, SO; Thomas, JE; Pichler, M Non-coding RNAs Enabling Prognostic Stratification and Prediction of Therapeutic Response in Colorectal Cancer Patients.
Adv Exp Med Biol. 2016; 937(4):183-204
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Sadovnik, I; Hoelbl-Kovacic, A; Herrmann, H; Eisenwort, G; Cerny-Reiterer, S; Warsch, W; Hoermann, G; Greiner, G; Blatt, K; Peter, B; Stefanzl, G; Berger, D; Bilban, M; Herndlhofer, S; Sill, H; Sperr, WR; Streubel, B; Mannhalter, C; Holyoake, TL; Sexl, V; Valent, P Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.
Clin Cancer Res. 2016; 22(8):2051-2061 [OPEN ACCESS]
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Scheipl, S; Barnard, M; Cottone, L; Jorgensen, M; Drewry, DH; Zuercher, WJ; Turlais, F; Ye, H; Leite, AP; Smith, JA; Leithner, A; Möller, P; Brüderlein, S; Guppy, N; Amary, F; Tirabosco, R; Strauss, SJ; Pillay, N; Flanagan, AM EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen.
J Pathol. 2016; 239(3):320-334 [OPEN ACCESS]
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Uttarkar, S; Piontek, T; Dukare, S; Schomburg, C; Schlenke, P; Berdel, WE; Müller-Tidow, C; Schmidt, TJ; Klempnauer, KH Small-Molecule Disruption of the Myb/p300 Cooperation Targets Acute Myeloid Leukemia Cells.
Mol Cancer Ther. 2016; 15(12):2905-2915 [OPEN ACCESS]
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2015

Dehghan Esmatabadi, MJ; Farhangi, B; Safari, Z; Kazerooni, H; Shirzad, H; Zolghadr, F; Sadeghizadeh, M Dendrosomal curcumin inhibits metastatic potential of human SW480 colon cancer cells through Down-regulation of Claudin1, Zeb1 and Hef1-1 gene expression.
Asian Pac J Cancer Prev. 2015; 16(6):2473-2481 [OPEN ACCESS]
PubMed

 

Fischer, C; Leithner, K; Wohlkoenig, C; Quehenberger, F; Bertsch, A; Olschewski, A; Olschewski, H; Hrzenjak, A Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization.
Mol Cancer. 2015; 14(8):4-4 [OPEN ACCESS]
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Fisser, MC; Rommer, A; Steinleitner, K; Heller, G; Herbst, F; Wiese, M; Glimm, H; Sill, H; Wieser, R Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.
Mol Carcinog. 2015; 54(12):1815-1819 [OPEN ACCESS]
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Fuchs, R; Schwach, G; Stracke, A; Meier-Allard, N; Absenger, M; Ingolic, E; Haas, HS; Pfragner, R; Sadjak, A The anti-hypertensive drug prazosin induces apoptosis in the medullary thyroid carcinoma cell line TT.
Anticancer Res. 2015; 35(1):31-38 [OPEN ACCESS]
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Fuchs, R; Stracke, A; Ebner, N; Zeller, CW; Raninger, AM; Schittmayer, M; Kueznik, T; Absenger-Novak, M; Birner-Gruenberger, R The cytotoxicity of the α1-adrenoceptor antagonist prazosin is linked to an endocytotic mechanism equivalent to transport-P.
Toxicology. 2015; 338(6):17-29 [OPEN ACCESS]
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Lohberger, B; Kretschmer, N; Bernhart, E; Rinner, B; Stuendl, N; Kaltenegger, H; Kahl, S; Bauer, R; Leithner, A 25-O-acetyl-23,24-dihydro-cucurbitacin F induces cell cycle G2/M arrest and apoptosis in human soft tissue sarcoma cells.
J Ethnopharmacol. 2015; 164(36):265-272
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Mayr, C; Neureiter, D; Pichler, M; Berr, F; Wagner, A; Kiesslich, T; Namberger, K Cytotoxic effects of chemokine receptor 4 inhibition by AMD3100 in biliary tract cancer cells: Potential drug synergism with gemcitabine.
Mol Med Rep. 2015; 12(2):2247-2252 [OPEN ACCESS]
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Mayr, C; Neureiter, D; Wagner, A; Pichler, M; Kiesslich, T The role of polycomb repressive complexes in biliary tract cancer.
Expert Opin Ther Targets. 2015; 19(3):363-375
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Mayr, C; Wagner, A; Neureiter, D; Pichler, M; Jakab, M; Illig, R; Berr, F; Kiesslich, T The green tea catechin epigallocatechin gallate induces cell cycle arrest and shows potential synergism with cisplatin in biliary tract cancer cells.
BMC Complement Altern Med. 2015; 15(6):194-194 [OPEN ACCESS]
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Wenzl, K; Troppan, K; Neumeister, P; Deutsch, AJ The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.
Curr Drug Targets. 2015; 16(1):38-46
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2014

Adam, C; Baeurle, A; Brodsky, JL; Wipf, P; Schrama, D; Becker, JC; Houben, R The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.
PLoS One. 2014; 9(4):e92041-e92041 [OPEN ACCESS]
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Fröhlich, E; Wahl, R The current role of targeted therapies to induce radioiodine uptake in thyroid cancer.
CANCER TREAT REV. 2014; 40(5): 665-674.
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Heiduschka, G; Lill, C; Schneider, S; Seemann, R; Kornek, G; Schmid, R; Kotowski, U; Thurnher, D The effect of cilengitide in combination with irradiation and chemotherapy in head and neck squamous cell carcinoma cell lines.
Strahlenther Onkol. 2014; 190(5): 472-479.
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Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12):2393-2403 [OPEN ACCESS]
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Kiesslich, T; Mayr, C; Wachter, J; Bach, D; Fuereder, J; Wagner, A; Alinger, B; Pichler, M; Di Fazio, P; Ocker, M; Berr, F; Neureiter, D Activated hedgehog pathway is a potential target for pharmacological intervention in biliary tract cancer.
Mol Cell Biochem. 2014; 396(1-2):257-268
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Krstic, J; Maslovaric, I; Santibanez, JF Novel patents and cancer therapies for transforming growth factor-beta and urokinase type plasminogen activator: potential use of their interplay in tumorigenesis.
Recent Pat Anticancer Drug Discov. 2014; 9(3): 354-371.
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Kutasy, B; Friedmacher, F; Duess, JW; Puri, P Prenatal administration of retinoic acid increases the trophoblastic insulin-like growth factor 2 protein expression in the nitrofen model of congenital diaphragmatic hernia.
Pediatr Surg Int. 2014; 30(2): 137-142.
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Schelch, K; Hoda, MA; Klikovits, T; Münzker, J; Ghanim, B; Wagner, C; Garay, T; Laszlo, V; Setinek, U; Dome, B; Filipits, M; Pirker, C; Heffeter, P; Selzer, E; Tovari, J; Torok, S; Kenessey, I; Holzmann, K; Grasl-Kraupp, B; Marian, B; Klepetko, W; Berger, W; Hegedus, B; Grusch, M Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.
Am J Respir Crit Care Med. 2014; 190(7):763-772
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Smolle, E; Taucher, V; Petru, E; Haybaeck, J Targeted treatment of ovarian cancer--the multiple - kinase - inhibitor sorafenib as a potential option.
Anticancer Res. 2014; 34(4):1519-1530
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Walter, I; Wolfesberger, B; Miller, I; Mair, G; Burger, S; Gallè, B; Steinborn, R Human osteosarcoma cells respond to sorafenib chemotherapy by downregulation of the tumor progression factors S100A4, CXCR4 and the oncogene FOS.
Oncol Rep. 2014; 31(3):1147-1156 [OPEN ACCESS]
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2013

Lohberger, B; Rinner, B; Stuendl, N; Kaltenegger, H; Steinecker-Frohnwieser, B; Bernhart, E; Bonyadi Rad, E; Weinberg, AM; Leithner, A; Bauer, R; Kretschmer, N Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.
PLoS One. 2013; 8(6):e66300-e66300 [OPEN ACCESS]
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Okic-Djordjevic, I; Trivanovic, D; Krstic, J; Jaukovic, A; Mojsilovic, S; Santibanez, JF; Terzic, M; Vesovic, D; Bugarski, D GE132+Natural: Novel promising dietetic supplement with antiproliferative influence on prostate, colon, and breast cancer cells.
J BUON. 2013; 18(2): 504-510.
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Shirsath, N; Rathos, M; Chaudhari, U; Sivaramakrishnan, H; Joshi, K Potentiation of anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the cyclin-dependent kinase inhibitor P276-00 in human non-small-cell lung cancer cell lines.
Lung Cancer. 2013; 82(2):214-221
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van Oosterwijk, JG; Meijer, D; van Ruler, MA; van den Akker, BE; Oosting, J; Krenács, T; Picci, P; Flanagan, AM; Liegl-Atzwanger, B; Leithner, A; Athanasou, N; Daugaard, S; Hogendoorn, PC; Bovée, JV Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.
Am J Pathol. 2013; 182(4):1347-1356 [OPEN ACCESS]
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2012

Deutsch, AJ; Angerer, H; Fuchs, TE; Neumeister, P The nuclear orphan receptors NR4A as therapeutic target in cancer therapy.
Anticancer Agents Med Chem. 2012; 12(9):1001-1014
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Hoda, MA; Münzker, J; Ghanim, B; Schelch, K; Klikovits, T; Laszlo, V; Sahin, E; Bedeir, A; Lackner, A; Dome, B; Setinek, U; Filipits, M; Eisenbauer, M; Kenessey, I; Török, S; Garay, T; Hegedus, B; Catania, A; Taghavi, S; Klepetko, W; Berger, W; Grusch, M Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells.
Br J Cancer. 2012; 107(12):1978-1986 [OPEN ACCESS]
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Kiesslich, T; Berr, F; Alinger, B; Kemmerling, R; Pichler, M; Ocker, M; Neureiter, D Current status of therapeutic targeting of developmental signalling pathways in oncology.
Curr Pharm Biotechnol. 2012; 13(11):2184-2220
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Ning, Y; Labonte, MJ; Zhang, W; Bohanes, PO; Gerger, A; Yang, D; Benhaim, L; Paez, D; Rosenberg, DO; Nagulapalli Venkata, KC; Louie, SG; Petasis, NA; Ladner, RD; Lenz, HJ The CXCR2 antagonist, SCH-527123, shows antitumor activity and sensitizes cells to oxaliplatin in preclinical colon cancer models.
Mol Cancer Ther. 2012; 11(6):1353-1364 [OPEN ACCESS]
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Rausch, V; Liu, L; Apel, A; Rettig, T; Gladkich, J; Labsch, S; Kallifatidis, G; Kaczorowski, A; Groth, A; Gross, W; Gebhard, MM; Schemmer, P; Werner, J; Salnikov, AV; Zentgraf, H; Büchler, MW; Herr, I Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment.
J Pathol. 2012; 227(3):325-335
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Schwach, G; Thamyongkit, P; Reith, LM; Svejda, B; Knör, G; Pfragner, R; Schoefberger, W A water soluble tri-cationic porphyrin-EDTA conjugate induces apoptosis in human neuroendocrine tumor cell lines.
Bioorg Chem. 2012; 40(1): 108-113. [OPEN ACCESS]
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Shirsath, NP; Manohar, SM; Joshi, KS P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines.
Mol Cancer. 2012; 11:77-77 [OPEN ACCESS]
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