Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: ADENOSINE TRIPHOSPHATE - METABOLISM , . Treffer: 57

2022

Gross, D; Bischof, H; Maier, S; Sporbeck, K; Birkenfeld, AL; Malli, R; Ruth, P; Proikas-Cezanne, T; Lukowski, R IKCa channels control breast cancer metabolism including AMPK-driven autophagy.
Cell Death Dis. 2022; 13(10): 902 Doi: 10.1038/s41419-022-05329-z [OPEN ACCESS]
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2020

Kolleritsch, S; Kien, B; Schoiswohl, G; Diwoky, C; Schreiber, R; Heier, C; Maresch, LK; Schweiger, M; Eichmann, TO; Stryeck, S; Krenn, P; Tomin, T; Schittmayer, M; Kolb, D; Rülicke, T; Hoefler, G; Wolinski, H; Madl, T; Birner-Gruenberger, R; Haemmerle, G Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice.
Cardiovasc Res. 2020; 116(2):339-352 Doi: 10.1093/cvr/cvz119 [OPEN ACCESS]
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2016

Madreiter-Sokolowski, CT; Gottschalk, B; Parichatikanond, W; Eroglu, E; Klec, C; Waldeck-Weiermair, M; Malli, R; Graier, WF Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria.
Cell Physiol Biochem. 2016; 39(4):1404-1420 Doi: 10.1159/000447844 [OPEN ACCESS]
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Pelzmann, B; Di Giuro, CM; Zorn-Pauly, K; Rossmann, C; Hallström, S; Groschner, K; Fameli, N Functional impairment of endothelial cells by the antimycotic amphotericin B.
Biochem Biophys Res Commun. 2016; 472(1):40-45 Doi: 10.1016/j.bbrc.2016.02.054
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Zierer, BK; Rübbelke, M; Tippel, F; Madl, T; Schopf, FH; Rutz, DA; Richter, K; Sattler, M; Buchner, J Importance of cycle timing for the function of the molecular chaperone Hsp90.
Nat Struct Mol Biol. 2016; 23(11):1020-1028 Doi: 10.1038/nsmb.3305 [OPEN ACCESS]
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2015

Bao, Y; Ledderose, C; Graf, AF; Brix, B; Birsak, T; Lee, A; Zhang, J; Junger, WG mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis.
J Cell Biol. 2015; 210(7):1153-1164 Doi: 10.1083/jcb.201503066 [OPEN ACCESS]
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Fritsch, M; Koliaki, C; Livingstone, R; Phielix, E; Bierwagen, A; Meisinger, M; Jelenik, T; Strassburger, K; Zimmermann, S; Brockmann, K; Wolff, C; Hwang, JH; Szendroedi, J; Roden, M Time course of postprandial hepatic phosphorus metabolites in lean, obese, and type 2 diabetes patients.
Am J Clin Nutr. 2015; 102(5): 1051-1058. Doi: 10.3945/ajcn.115.107599 [OPEN ACCESS]
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Wende, AR; O'Neill, BT; Bugger, H; Riehle, C; Tuinei, J; Buchanan, J; Tsushima, K; Wang, L; Caro, P; Guo, A; Sloan, C; Kim, BJ; Wang, X; Pereira, RO; McCrory, MA; Nye, BG; Benavides, GA; Darley-Usmar, VM; Shioi, T; Weimer, BC; Abel, ED Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.
Mol Cell Biol. 2015; 35(5): 831-846. Doi: 10.1128/MCB.01109-14 [OPEN ACCESS]
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2014

Alderson, TR; Kim, JH; Cai, K; Frederick, RO; Tonelli, M; Markley, JL The specialized Hsp70 (HscA) interdomain linker binds to its nucleotide-binding domain and stimulates ATP hydrolysis in both cis and trans configurations.
Biochemistry. 2014; 53(46): 7148-59. Doi: 10.1021/bi5010552 [OPEN ACCESS]
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Bao, Y; Ledderose, C; Seier, T; Graf, AF; Brix, B; Chong, E; Junger, WG Mitochondria regulate neutrophil activation by generating ATP for autocrine purinergic signaling.
J Biol Chem. 2014; 289(39):26794-26803 Doi: 10.1074/jbc.M114.572495 [OPEN ACCESS]
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Geier, O; Weng, AM; Toepell, A; Hahn, D; Spindler, M; Beer, M; Köstler, H Acquisition-weighted chemical shift imaging improves SLOOP quantification of human cardiac phosphorus metabolites.
Z Med Phys. 2014; 24(1):49-54 Doi: 10.1016/j.zemedi.2013.01.002
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Loibl, M; Klein, I; Prattes, M; Schmidt, C; Kappel, L; Zisser, G; Gungl, A; Krieger, E; Pertschy, B; Bergler, H The drug diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1.
J Biol Chem. 2014; 289(7): 3913-3922. Doi: 10.1074/jbc.M113.536110 [OPEN ACCESS]
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Valkovič, L; Gajdošík, M; Traussnigg, S; Wolf, P; Chmelík, M; Kienbacher, C; Bogner, W; Krebs, M; Trauner, M; Trattnig, S; Krššák, M Application of localized ³¹P MRS saturation transfer at 7 T for measurement of ATP metabolism in the liver: reproducibility and initial clinical application in patients with non-alcoholic fatty liver disease.
Eur Radiol. 2014; 24(7): 1602-1609. Doi: 10.1007/s00330-014-3141-x
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Vishnu, N; Jadoon Khan, M; Karsten, F; Groschner, LN; Waldeck-Weiermair, M; Rost, R; Hallström, S; Imamura, H; Graier, WF; Malli, R ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release.
Mol Biol Cell. 2014; 25(3):368-379 Doi: 10.1091/mbc.E13-07-0433 [OPEN ACCESS]
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2013

Bosche, B; Schäfer, M; Graf, R; Härtel, FV; Schäfer, U; Noll, T Lithium prevents early cytosolic calcium increase and secondary injurious calcium overload in glycolytically inhibited endothelial cells.
Biochem Biophys Res Commun. 2013; 434(2):268-272 Doi: 10.1016/j.bbrc.2013.03.047
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Fickert, P; Pollheimer, MJ; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thüringer, A; Zollner, G; Denk, H; Trauner, M Differential effects of norUDCA and UDCA in obstructive cholestasis in mice.
J Hepatol. 2013; 58(6):1201-1208 Doi: 10.1016/j.jhep.2013.01.026 [OPEN ACCESS]
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Forbes, JM; Ke, BX; Nguyen, TV; Henstridge, DC; Penfold, SA; Laskowski, A; Sourris, KC; Groschner, LN; Cooper, ME; Thorburn, DR; Coughlan, MT Deficiency in mitochondrial complex I activity due to Ndufs6 gene trap insertion induces renal disease.
Antioxid Redox Signal. 2013; 19(4):331-343 Doi: 10.1089/ars.2012.4719
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Nikam, A; Patankar, JV; Lackner, C; Schöck, E; Kratky, D; Zatloukal, K; Abuja, PM Transition between acute and chronic hepatotoxicity in mice is associated with impaired energy metabolism and induction of mitochondrial heme oxygenase-1.
PLoS One. 2013; 8(6):e66094-e66094 Doi: 10.1371/journal.pone.0066094 [OPEN ACCESS]
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Sivakumaran, V; Stanley, BA; Tocchetti, CG; Ballin, JD; Caceres, V; Zhou, L; Keceli, G; Rainer, PP; Lee, DI; Huke, S; Ziolo, MT; Kranias, EG; Toscano, JP; Wilson, GM; O'Rourke, B; Kass, DA; Mahaney, JE; Paolocci, N HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Antioxid Redox Signal. 2013; 19(11):1185-1197 Doi: 10.1089/ars.2012.5057 [OPEN ACCESS]
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Stadlbauer, V; Stiegler, P; Taeubl, P; Sereinigg, M; Puntschart, A; Bradatsch, A; Curcic, P; Seifert-Held, T; Zmugg, G; Stojakovic, T; Leopold, B; Blattl, D; Horki, V; Mayrhauser, U; Wiederstein-Grasser, I; Leber, B; Jürgens, G; Tscheliessnigg, K; Hallström, S Energy status of pig donor organs after ischemia is independent of donor type.
J Surg Res. 2013; 180(2):356-367 Doi: 10.1016/j.jss.2012.05.025
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2012

Alam, MR; Groschner, LN; Parichatikanond, W; Kuo, L; Bondarenko, AI; Rost, R; Waldeck-Weiermair, M; Malli, R; Graier, WF Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells.
J Biol Chem. 2012; 287(41):34445-34454 Doi: 10.1074/jbc.M112.392084 [OPEN ACCESS]
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2010

Chandak, PG; Radovic, B; Aflaki, E; Kolb, D; Buchebner, M; Fröhlich, E; Magnes, C; Sinner, F; Haemmerle, G; Zechner, R; Tabas, I; Levak-Frank, S; Kratky, D Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
J Biol Chem. 2010; 285(26):20192-20201 Doi: 10.1074/jbc.M110.107854 [OPEN ACCESS]
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2009

Beer, M; Winkelmann, V; Becker, JC; Terheyden, P; Stenzel, M; Brocker, EB; Hahn, D; Kostler, H Spectroscopic imaging of the human liver using 3D CSI: optimization and application in patients with metastatic uvea melanoma
Rofo. 2009; 181(1):60-66 Doi: 10.1055/s-2008-1027887 [OPEN ACCESS]
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Boudina, S; Bugger, H; Sena, S; O'Neill, BT; Zaha, VG; Ilkun, O; Wright, JJ; Mazumder, PK; Palfreyman, E; Tidwell, TJ; Theobald, H; Khalimonchuk, O; Wayment, B; Sheng, X; Rodnick, KJ; Centini, R; Chen, D; Litwin, SE; Weimer, BE; Abel, ED Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.
Circulation. 2009; 119(9): 1272-1283. Doi: 10.1161/CIRCULATIONAHA.108.792101 [OPEN ACCESS]
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Bugger, H; Chen, D; Riehle, C; Soto, J; Theobald, HA; Hu, XX; Ganesan, B; Weimer, BC; Abel, ED Tissue-specific remodeling of the mitochondrial proteome in type 1 diabetic akita mice.
Diabetes. 2009; 58(9): 1986-1997. Doi: 10.2337/db09-0259 [OPEN ACCESS]
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Schicker, K; Hussl, S; Chandaka, GK; Kosenburger, K; Yang, JW; Waldhoer, M; Sitte, HH; Boehm, S A membrane network of receptors and enzymes for adenine nucleotides and nucleosides.
Biochim Biophys Acta. 2009; 1793(2): 325-334. Doi: 10.1016/j.bbamcr.2008.09.014 [OPEN ACCESS]
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Sedej, S; Gurung, IS; Binz, T; Rupnik, M Phosphatidylinositol-4,5-bisphosphate-dependent Facilitation of the ATP-dependent Secretory Activity in Mouse Pituitary Cells.
Ann N Y Acad Sci. 2009; 1152(1): 165-173. Doi: 10.1111/j.1749-6632.2008.04002.x
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Stadlbauer, V; Mookerjee, RP; Wright, GAK; Davies, NA; Jurgens, G; Hallstrom, S; Jalan, R Role of Toll-like receptors 2, 4, and 9 in mediating neutrophil dysfunction in alcoholic hepatitis.
AMER J PHYSIOL-GASTROINTEST L. 2009; 296(1): G15-G22. Doi: 10.1152/ajpgi.90512.2008 [OPEN ACCESS]
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2006

Kostler, H; Landschutz, W; Koeppe, S; Seyfarth, T; Lipke, C; Sandstede, J; Spindler, M; von Kienlin, M; Hahn, D; Beer, M Age and gender dependence of human cardiac phosphorus metabolites determined by SLOOP P-31 MR spectroscopy
Magn Reson Med. 2006; 56(4):907-911 Doi: 10.1002/mrm.21027
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2004

Beer, M; Spindler, M; Sandstede, JJW; Remmert, H; Beer, S; Kostler, H; Hahn, D Detection of myocardial infarctions by acquisition-weighted P-31-MR spectroscopy in humans
J Magn Reson Imaging. 2004; 20(5):798-802 Doi: 10.1002/jmri.20185
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Bretner, M; Schalinski, S; Haag, A; Lang, M; Schmitz, H; Baier, A; Behrens, SE; Kulikowski, T; Borowski, P Synthesis and evaluation of ATP-binding site directed potential inhibitors of nucleoside triphosphatases/helicases and polymerases of hepatitis C and other selected Flaviviridae viruses.
Antivir Chem Chemother. 2004; 15(1): 35-42. Doi: 10.1177/095632020401500104
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2003

Esenabhalu, VE; Schaeffer, G; Graier, WF Free fatty acid overload attenuates Ca2+ signaling and NO production in endothelial cells.
Antioxid Redox Signal. 2003; 5(2):147-153 Doi: 10.1089/152308603764816505
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Ugurel, S; Tilgen, W; Reinhold, U Chemosensitivity testing in malignant melanoma.
Recent Results Cancer Res. 2003; 161(8):81-92 Doi: 10.1007/978-3-642-19022-3_8
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Wascher, TC; Boes, U Ischemia in type 2 diabetes: tissue selectivity of sulfonylureas and clinical implications.
Metabolism. 2003; 52(8 Suppl 1):3-5 Doi: 10.1016/S0026-0495(03)00211-7
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Zima, AV; Kockskämper, J; Mejia-Alvarez, R; Blatter, LA Pyruvate modulates cardiac sarcoplasmic reticulum Ca2+ release in rats via mitochondria-dependent and -independent mechanisms.
J Physiol. 2003; 550(Pt 3):765-783 Doi: 10.1113/jphysiol.2003.040345 [OPEN ACCESS]
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2002

Stevens, B; Porta, S; Haak, LL; Gallo, V; Fields, RD Adenosine: a neuron-glial transmitter promoting myelination in the CNS in response to action potentials.
Neuron. 2002; 36(5):855-868 Doi: 10.1016%2FS0896-6273%2802%2901067-X [OPEN ACCESS]
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2001

Beer, M; Sandstede, J; Weilbach, F; Spindler, M; Buchner, S; Krug, A; Kostler, H; Pabst, T; Kenn, W; Landschutz, W; von Kienlin, M; Toyka, KV; Ertl, G; Gold, R; Hahn, D Cardiac metabolism and function in patients with multiple sclerosis: A combined P-31-MR-spectroscopy and MRI study
Rofo. 2001; 173(5):399-404 Doi: 10.1055/s-2001-13339
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Kostler, H; Beer, M; Landschutz, W; Buchner, S; Sandstede, J; Pabst, T; Kenn, W; Neubauer, S; von Kienlin, M; Hahn, D P-31-MR spectroscopy of all regions of the human heart at 1.5T with acquisition-weighted chemical shift imaging.
Rofo. 2001; 173(12):1093-1098 Doi: 10.1055/s-2001-18888
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2000

Beer, M; Sandstede, J; Landschutz, W; Viehrig, M; Harre, K; Horn, M; Meininger, M; Pabst, T; Kenn, W; Haase, A; von Kienlin, M; Neubauer, S; Hahn, D Altered energy metabolism after myocardial infarction assessed by P-31-MR-spectroscopy in humans
Eur Radiol. 2000; 10(8):1323-1328 Doi: 10.1007/s003300000316
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Pagel, PS; Toller, WG; Gross, ER; Gare, M; Kersten, JR; Warltier, DC K(ATP) channels mediate the beneficial effects of chronic ethanol ingestion.
AMER J PHYSIOL-HEART CIRC PHY 2000 279: H2574-H2579. Doi: 10.1152/ajpheart.2000.279.5.H2574 [OPEN ACCESS]
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Toller, WG; Gross, ER; Kersten, JR; Pagel, PS; Gross, GJ; Warltier, DC Sarcolemmal and mitochondrial adenosine triphosphate- dependent potassium channels: mechanism of desflurane-induced cardioprotection.
Anesthesiology. 2000; 92(6):1731-1739 Doi: 10.1097/00000542-200006000-00033 [OPEN ACCESS]
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1999

Toller, WG; Kersten, JR; Pagel, PS; Hettrick, DA; Warltier, DC Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs.
Anesthesiology. 1999; 91(5):1437-1446 Doi: 10.1097/00000542-199911000-00037 [OPEN ACCESS]
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1998

Grisold, M; Köppel, H; Gasser, R First description of the effect of a non-sulfonylurea compound, tetramethylpyrazine, on coronary response to desoxyglucose-induced ischemia.
Acta Med Austriaca. 1998; 25(1):16-20
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1997

Trauner, M Molecular alterations of canalicular transport systems in experimental models of cholestasis: possible functional correlations.
Yale J Biol Med. 1997; 70(4):365-378 [OPEN ACCESS]
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1996

Köppel, H; Gasser, R; Klein, W; Holzmann, S ACE inhibitors with SH groups have no effect of ATP-dependent K channels--a dissertation
Acta Med Austriaca. 1996; 23(3):109-112
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Olschewski, A; Bräu, ME; Olschewski, H; Hempelmann, G; Vogel, W ATP-dependent potassium channel in rat cardiomyocytes is blocked by lidocaine. Possible impact on the antiarrhythmic action of lidocaine.
Circulation. 1996; 93(4):656-659 Doi: 10.1161/01.CIR.93.4.656 [OPEN ACCESS]
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1995

Hay, JC; Fisette, PL; Jenkins, GH; Fukami, K; Takenawa, T; Anderson, RA; Martin, TF ATP-dependent inositide phosphorylation required for Ca(2+)-activated secretion.
Nature. 1995; 374(6518):173-177 Doi: 10.1038/374173a0
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Martin, TF; Hay, JC; Banerjee, A; Barry, VA; Ann, K; Yom, HC; Porter, BW; Kowalchyk, JA Late ATP-dependent and Ca++-activated steps of dense core granule exocytosis.
Cold Spring Harb Symp Quant Biol. 1995; 60(6518):197-204 Doi: 10.1101/SQB.1995.060.01.022
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Schulz, R; Post, H; Sakka, S; Wallbridge, DR; Heusch, G Intraischemic preconditioning. Increased tolerance to sustained low-flow ischemia by a brief episode of no-flow ischemia without intermittent reperfusion.
Circ Res. 1995; 76(6):942-950 Doi: 10.1161/01.RES.76.6.942 [OPEN ACCESS]
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Schulz, R; Rose, J; Post, H; Heusch, G Involvement of endogenous adenosine in ischaemic preconditioning in swine.
Pflugers Arch. 1995; 430(2):273-282 Doi: 10.1007/BF00374659
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