Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: AML, . Treffer: 144

2020

Daga, S; Rosenberger, A; Kashofer, K; Heitzer, E; Quehenberger, F; Halbwedl, I; Graf, R; Krisper, N; Prietl, B; Höfler, G; Reinisch, A; Zebisch, A; Sill, H; Wölfler, A Sensitive and broadly applicable residual disease detection in acute myeloid leukemia using flow cytometry-based leukemic cell enrichment followed by mutational profiling.
Am J Hematol. 2020;
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Dutta, S; Pregartner, G; Rücker, FG; Heitzer, E; Zebisch, A; Bullinger, L; Berghold, A; Döhner, K; Sill, H Functional Classification of TP53 Mutations in Acute Myeloid Leukemia.
Cancers (Basel). 2020; 12(3): [OPEN ACCESS]
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Geissler, K; Jäger, E; Barna, A; Gurbisz, M; Graf, T; Graf, E; Nösslinger, T; Pfeilstöcker, M; Tüchler, H; Sliwa, T; Keil, F; Geissler, C; Heibl, S; Thaler, J; Machherndl-Spandl, S; Zach, O; Weltermann, A; Bettelheim, P; Stauder, R; Zebisch, A; Sill, H; Schwarzinger, I; Schneeweiss, B; Öhler, L; Ulsperger, E; Kusec, R; Germing, U; Sperr, WR; Knöbl, P; Jäger, U; Hörmann, G; Valent, P Correlation of RAS-Pathway Mutations and Spontaneous Myeloid Colony Growth with Progression and Transformation in Chronic Myelomonocytic Leukemia-A Retrospective Analysis in 337 Patients.
Int J Mol Sci. 2020; 21(8): [OPEN ACCESS]
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Hatzl, S; Perfler, B; Wurm, S; Uhl, B; Quehenberger, F; Ebner, S; Troppmair, J; Reinisch, A; Wölfler, A; Sill, H; Zebisch, A Increased Expression of Micro-RNA-23a Mediates Chemoresistance to Cytarabine in Acute Myeloid Leukemia.
Cancers (Basel). 2020; 12(2): [OPEN ACCESS]
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Koldobskiy, MA; Abante, J; Jenkinson, G; Pujadas, E; Tetens, A; Zhao, F; Tryggvadottir, R; Idrizi, A; Reinisch, A; Majeti, R; Goutsias, J; Feinberg, AP A Dysregulated DNA Methylation Landscape Linked to Gene Expression in MLL-Rearranged AML.
Epigenetics. 2020; 1-18.
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Kuendgen, A; Nomdedeu, M; Tuechler, H; Garcia-Manero, G; Komrokji, RS; Sekeres, MA; Della Porta, MG; Cazzola, M; DeZern, AE; Roboz, GJ; Steensma, DP; Van de Loosdrecht, AA; Schlenk, RF; Grau, J; Calvo, X; Blum, S; Pereira, A; Valent, P; Costa, D; Giagounidis, A; Xicoy, B; Döhner, H; Platzbecker, U; Pedro, C; Lübbert, M; Oiartzabal, I; Díez-Campelo, M; Cedena, MT; Machherndl-Spandl, S; López-Pavía, M; Baldus, CD; Martinez-de-Sola, M; Stauder, R; Merchan, B; List, A; Ganster, C; Schroeder, T; Voso, MT; Pfeilstöcker, M; Sill, H; Hildebrandt, B; Esteve, J; Nomdedeu, B; Cobo, F; Haas, R; Sole, F; Germing, U; Greenberg, PL; Haase, D; Sanz, G Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification-an approach to classification of patients with t-MDS.
Leukemia. 2020;
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Nguyen, CH; Grandits, AM; Purton, LE; Sill, H; Wieser, R All-trans retinoic acid in non-promyelocytic acute myeloid leukemia: driver lesion dependent effects on leukemic stem cells.
Cell Cycle. 2020; 1-16.
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Sill, H; Zebisch, A; Haase, D Acute Myeloid Leukemia and Myelodysplastic Syndromes with TP53 Aberrations - a Distinct Stem Cell Disorder.
Clin Cancer Res. 2020;
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Skálová, A; Banečkova, M; Thompson, LDR; Ptáková, N; Stevens, TM; Brcic, L; Hyrcza, M; Michal, M; Simpson, RHW; Santana, T; Michal, M; Vaněček, T; Leivo, I Expanding the Molecular Spectrum of Secretory Carcinoma of Salivary Glands With a Novel VIM-RET Fusion.
Am J Surg Pathol. 2020; 44(10):1295-1307
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Turro, E; Astle, WJ; Megy, K; Gräf, S; Greene, D; Shamardina, O; Allen, HL; Sanchis-Juan, A; Frontini, M; Thys, C; Stephens, J; Mapeta, R; Burren, OS; Downes, K; Haimel, M; Tuna, S; Deevi, SVV; Aitman, TJ; Bennett, DL; Calleja, P; Carss, K; Caulfield, MJ; Chinnery, PF; Dixon, PH; Gale, DP; James, R; Koziell, A; Laffan, MA; Levine, AP; Maher, ER; Markus, HS; Morales, J; Morrell, NW; Mumford, AD; Ormondroyd, E; Rankin, S; Rendon, A; Richardson, S; Roberts, I; Roy, NBA; Saleem, MA; Smith, KGC; Stark, H; Tan, RYY; Themistocleous, AC; Thrasher, AJ; Watkins, H; Webster, AR; Wilkins, MR; Williamson, C; Whitworth, J; Humphray, S; Bentley, DR; NIHR BioResource for the 100,000 Genomes Project; Kingston, N; Walker, N; Bradley, JR; Ashford, S; Penkett, CJ; Freson, K; Stirrups, KE; Raymond, FL; Ouwehand, WH Whole-genome sequencing of patients with rare diseases in a national health system.
Nature. 2020; 583(7814): 96-102.
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2019

Aigner, P; Mizutani, T; Horvath, J; Eder, T; Heber, S; Lind, K; Just, V; Moll, HP; Yeroslaviz, A; Fischer, MJM; Kenner, L; Győrffy, B; Sill, H; Grebien, F; Moriggl, R; Casanova, E; Stoiber, D STAT3β is a tumor suppressor in acute myeloid leukemia.
Blood Adv. 2019; 3(13): 1989-2002. [OPEN ACCESS]
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Daga, S; Rosenberger, A; Quehenberger, F; Krisper, N; Prietl, B; Reinisch, A; Zebisch, A; Sill, H; Wölfler, A High GPR56 surface expression correlates with a leukemic stem cell gene signature in CD34-positive AML.
Cancer Med. 2019; 8(4):1771-1778 [OPEN ACCESS]
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Gluexam, T; Grandits, AM; Schlerka, A; Nguyen, CH; Etzler, J; Finkes, T; Fuchs, M; Scheid, C; Heller, G; Hackl, H; Harrer, N; Sill, H; Koller, E; Stoiber, D; Sommergruber, W; Wieser, R CGRP Signaling via CALCRL Increases Chemotherapy Resistance and Stem Cell Properties in Acute Myeloid Leukemia.
Int J Mol Sci. 2019; 20(23): [OPEN ACCESS]
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Good, WW; Gillette, KK; Bergquist, JA; Zenger, B; Tate, J; Rupp, LC; Anderson, D; Plank, G; MacLeod, RS Validation of Intramural Wavefront Reconstruction and Estimation of 3D Conduction Velocity.
Comput Cardiol (2010). 2019; 46: [OPEN ACCESS]
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Kröger, N; Eikema, DJ; Köster, L; Beelen, D; de Wreede, LC; Finke, J; Koenecke, C; Niederwieser, D; Bornhäuser, M; Schoenland, S; Potter, V; Wolschke, C; Maertens, J; Theobald, M; Kobbe, G; Itälä-Remes, M; Wulf, G; Kahls, P; Forcade, E; Greinix, H; Masszi, T; Yakoub-Agha, I; Chalandon, Y; Robin, M; Chronic Malignancies Working Party of the European Society for Blood Marrow Transplantation Impact of primary disease on outcome after allogeneic stem cell transplantation for transformed secondary acute leukaemia.
BRIT J HAEMATOL. 2019; 185(4): 725-732.
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Primhak, R; Tabin, N; Beydon, N; Bhatt, J; Eber, E; Hammer, J; Martinez-Gimeno, A; Midulla, F; Nenna, R; Paton, J; Ross Russell, R Update of the European paediatric respiratory medicine syllabus.
Breathe (Sheff). 2019; 15(3): 173-180. [OPEN ACCESS]
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Simell, BA; Törnwall, OM; Hämäläinen, I; Wichmann, HE; Anton, G; Brennan, P; Bouvard, L; Slimani, N; Moskal, A; Gunter, M; Zatloukal, K; Minion, JT; Soini, S; Mayrhofer, MT; Murtagh, MJ; van Ommen, GJ; Johansson, M; Perola, M; BBMRI-LPC Consortium (FP7 GA no. 313010) Transnational access to large prospective cohorts in Europe: Current trends and unmet needs.
NEW BIOTECHNOL. 2019; 49(1): 98-103. [OPEN ACCESS]
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Zebisch, A; Caraffini, V; Sill, H RAF Kinase Inhibitor Protein in Myeloid Leukemogenesis.
Int J Mol Sci. 2019; 20(22): [OPEN ACCESS]
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2018

Gaksch, L; Kashofer, K; Heitzer, E; Quehenberger, F; Daga, S; Hofer, S; Halbwedl, I; Graf, R; Krisper, N; Hoefler, G; Zebisch, A; Sill, H; Wölfler, A Residual disease detection using targeted parallel sequencing predicts relapse in cytogenetically normal acute myeloid leukemia.
Am J Hematol. 2018; 93(1):23-30 [OPEN ACCESS]
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Robier, C; Körber, C; Quehenberger, F; Neubauer, M; Wölfler, A The frequency of occurrence of fish-shaped red blood cells in different haematologic disorders.
Clin Chem Lab Med. 2018; 56(2):323-326
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Strenger, V; Merth, G; Lackner, H; Aberle, SW; Kessler, HH; Seidel, MG; Schwinger, W; Sperl, D; Sovinz, P; Karastaneva, A; Benesch, M; Urban, C Malignancy and chemotherapy induced haemophagocytic lymphohistiocytosis in children and adolescents-a single centre experience of 20 years.
Ann Hematol. 2018; 97(6):989-998 [OPEN ACCESS]
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2017

Chao, MP; Gentles, AJ; Chatterjee, S; Lan, F; Reinisch, A; Corces, MR; Xavy, S; Shen, J; Haag, D; Chanda, S; Sinha, R; Morganti, RM; Nishimura, T; Ameen, M; Wu, H; Wernig, M; Wu, JC; Majeti, R Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Cell Stem Cell. 2017; 20(3): 329-344. [OPEN ACCESS]
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Heidenreich, S; Ziagkos, D; de Wreede, LC; van Biezen, A; Finke, J; Platzbecker, U; Niederwieser, D; Einsele, H; Bethge, W; Schleuning, M; Beelen, DW; Tischer, J; Nagler, A; Glass, B; Maertens, J; Yáñez, L; Beguin, Y; Sill, H; Scheid, C; Stelljes, M; Ganser, A; Zachée, P; Selleslag, D; de Witte, T; Robin, M; Kröger, N Allogeneic Stem Cell Transplantation for Patients Age ≥ 70 Years with Myelodysplastic Syndrome: A Retrospective Study of the MDS Subcommittee of the Chronic Malignancies Working Party of the EBMT.
Biol Blood Marrow Transplant. 2017; 23(1):44-52 [OPEN ACCESS]
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Laederach, V; Mukaddam, K; Payer, M; Filippi, A; Kühl, S Deviations of different systems for guided implant surgery.
Clin Oral Implants Res. 2017; 28(9):1147-1151
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Peschel, I; Podmirseg, SR; Taschler, M; Duyster, J; Götze, KS; Sill, H; Nachbaur, D; Jäkel, H; Hengst, L FLT3 and FLT3-ITD phosphorylate and inactivate the cyclin-dependent kinase inhibitor p27Kip1 in acute myeloid leukemia.
Haematologica. 2017; 102(8):1378-1389 [OPEN ACCESS]
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Pleyer, L; Döhner, H; Dombret, H; Seymour, JF; Schuh, AC; Beach, CL; Swern, AS; Burgstaller, S; Stauder, R; Girschikofsky, M; Sill, H; Schlick, K; Thaler, J; Halter, B; Machherndl Spandl, S; Zebisch, A; Pichler, A; Pfeilstöcker, M; Autzinger, EM; Lang, A; Geissler, K; Voskova, D; Sperr, WR; Hojas, S; Rogulj, IM; Andel, J; Greil, R Azacitidine for Front-Line Therapy of Patients with AML: Reproducible Efficacy Established by Direct Comparison of International Phase 3 Trial Data with Registry Data from the Austrian Azacitidine Registry of the AGMT Study Group.
Int J Mol Sci. 2017; 18(2): [OPEN ACCESS]
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Reinisch, A; Hernandez, DC; Schallmoser, K; Majeti, R Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice.
Nat Protoc. 2017; 12(10): 2169-2188. [OPEN ACCESS]
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Santana da Silva, F; Jansen, L; Freitas, F; Schulz, S Ontological interpretation of biomedical database content.
J Biomed Semantics. 2017; 8(1):24-24 [OPEN ACCESS]
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Schulz, S; Rodrigues, JM; Rector, A; Chute, CG Interface Terminologies, Reference Terminologies and Aggregation Terminologies: A Strategy for Better Integration.
Stud Health Technol Inform. 2017; 245(12):940-944
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2016

Arriga, R; Caratelli, S; Coppola, A; Spagnoli, GC; Venditti, A; Amadori, S; Lanzilli, G; Lauro, D; Palomba, P; Sconocchia, T; Del Principe, MI; Maurillo, L; Buccisano, F; Capuani, B; Ferrone, S; Sconocchia, G Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage.
Oncotarget. 2016; 7(2): 2070-2079. [OPEN ACCESS]
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Bainschab, A; Quehenberger, F; Greinix, HT; Krause, R; Wölfler, A; Sill, H; Zebisch, A Infections in patients with acute myeloid leukemia treated with low-intensity therapeutic regimens: Risk factors and efficacy of antibiotic prophylaxis.
Leuk Res. 2016; 42(3):47-51
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Boehnke, K; Iversen, PW; Schumacher, D; Lallena, MJ; Haro, R; Amat, J; Haybaeck, J; Liebs, S; Lange, M; Schäfer, R; Regenbrecht, CR; Reinhard, C; Velasco, JA Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures.
J Biomol Screen. 2016; 21(9):931-941 [OPEN ACCESS]
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Dutta, S; Krause, A; Vosberg, S; Herold, T; Ksienzyk, B; Quintanilla-Martinez, L; Tizazu, B; Chopra, M; Graf, A; Krebs, S; Blum, H; Greif, PA; Vetter, A; Metzeler, K; Rothenberg-Thurley, M; Schneider, MR; Dahlhoff, M; Spiekermann, K; Zimber-Strobl, U; Wolf, E; Bohlander, SK The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.
Leukemia. 2016; 30(5):1166-1176
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Fößl, T; Ebner, M; Schön, S; Holzinger, A A Field Study of a Video Supported Seamless-Learning-Setting with Elementary Learners
EDUC TECHNOL SOC. 2016; 19(1): 321-336. [OPEN ACCESS]
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Hartmann, L; Dutta, S; Opatz, S; Vosberg, S; Reiter, K; Leubolt, G; Metzeler, KH; Herold, T; Bamopoulos, SA; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Hopfner, KP; Graf, A; Krebs, S; Blum, H; Middeke, JM; Stölzel, F; Thiede, C; Wolf, S; Bohlander, SK; Preiss, C; Chen-Wichmann, L; Wichmann, C; Sauerland, MC; Büchner, T; Berdel, WE; Wörmann, BJ; Braess, J; Hiddemann, W; Spiekermann, K; Greif, PA ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
Nat Commun. 2016; 7:11733-11733 [OPEN ACCESS]
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Hatzl, S; Geiger, O; Kuepper, MK; Caraffini, V; Seime, T; Furlan, T; Nussbaumer, E; Wieser, R; Pichler, M; Scheideler, M; Nowek, K; Jongen-Lavrencic, M; Quehenberger, F; Wölfler, A; Troppmair, J; Sill, H; Zebisch, A Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.
Cancer Res. 2016; 76(12):3644-3654 [OPEN ACCESS]
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Heier, C; Taschler, U; Radulovic, M; Aschauer, P; Eichmann, TO; Grond, S; Wolinski, H; Oberer, M; Zechner, R; Kohlwein, SD; Zimmermann, R Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism.
J Biol Chem. 2016; 291(22):11865-11875 [OPEN ACCESS]
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Hell, L; Thaler, J; Martinod, K; Ay, C; Posch, F; Wagner, DD; Pabinger, I OC-16 - Neutrophil extracellular traps and tissue factor-bearing microvesicles: a liaison dangereuse causing overt DIC in cancer patients?
Thromb Res. 2016; 140 Suppl 1(1):S174-S175
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Pleyer, L; Burgstaller, S; Stauder, R; Girschikofsky, M; Sill, H; Schlick, K; Thaler, J; Halter, B; Machherndl-Spandl, S; Zebisch, A; Pichler, A; Pfeilstöcker, M; Autzinger, EM; Lang, A; Geissler, K; Voskova, D; Geissler, D; Sperr, WR; Hojas, S; Rogulj, IM; Andel, J; Greil, R Azacitidine front-line in 339 patients with myelodysplastic syndromes and acute myeloid leukaemia: comparison of French-American-British and World Health Organization classifications.
J Hematol Oncol. 2016; 9(6):39-39 [OPEN ACCESS]
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Reinisch, A; Majeti, R Sticking It to the Niche: CD98 Mediates Critical Adhesive Signals in AML.
Cancer Cell. 2016; 30(5): 662-664. [OPEN ACCESS]
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Reinisch, A; Thomas, D; Corces, MR; Zhang, X; Gratzinger, D; Hong, WJ; Schallmoser, K; Strunk, D; Majeti, R A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.
Nat Med. 2016; 22(7): 812-821. [OPEN ACCESS]
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Uttarkar, S; Dassé, E; Coulibaly, A; Steinmann, S; Jakobs, A; Schomburg, C; Trentmann, A; Jose, J; Schlenke, P; Berdel, WE; Schmidt, TJ; Müller-Tidow, C; Frampton, J; Klempnauer, KH Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction.
Blood. 2016; 127(9):1173-1182 [OPEN ACCESS]
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Zebisch, A; Hatzl, S; Pichler, M; Wölfler, A; Sill, H Therapeutic Resistance in Acute Myeloid Leukemia: The Role of Non-Coding RNAs.
Int J Mol Sci. 2016; 17(12): [OPEN ACCESS]
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2015

Fisser, MC; Rommer, A; Steinleitner, K; Heller, G; Herbst, F; Wiese, M; Glimm, H; Sill, H; Wieser, R Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.
Mol Carcinog. 2015; 54(12):1815-1819 [OPEN ACCESS]
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Mayer, M; Gleiss, A; Hausler, G; Borkenstein, M; Kapelari, K; Kostl, G; Lassi, M; Schemper, M; Schmitt, K; Blumel, P BMI Reference Values for Austrian Boys and Girls.
AUST J CLIN ENDOCR M. 2015; 8(2): 38-40. [OPEN ACCESS]
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Mayer, M; Gleiss, A; Häusler, G; Borkenstein, M; Kapelari, K; Köstl, G; Lassi, M; Schemper, M; Schmitt, K; Blümel, P Weight and body mass index (BMI): current data for Austrian boys and girls aged 4 to under 19 years.
Ann Hum Biol. 2015; 42(1):45-55
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Reinisch, A; Chan, SM; Thomas, D; Majeti, R Biology and Clinical Relevance of Acute Myeloid Leukemia Stem Cells.
Semin Hematol. 2015; 52(3): 150-164. [OPEN ACCESS]
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Rosenkranz, AR; Ratzinger, M Efficacy, safety, and tolerability of antihypertensive therapy with aliskiren/amlodipine in clinical practice in Austria. The RALLY (Rasilamlo long lasting efficacy) study.
Wien Klin Wochenschr. 2015; 127(5-6):203-209
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Sinha, S; Thomas, D; Yu, L; Gentles, AJ; Jung, N; Corces-Zimmerman, MR; Chan, SM; Reinisch, A; Feinberg, AP; Dill, DL; Majeti, R Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition.
Blood. 2015; 125(2): 316-326. [OPEN ACCESS]
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Wenzl, K; Troppan, K; Neumeister, P; Deutsch, AJ The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.
Curr Drug Targets. 2015; 16(1):38-46
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