Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: 3-DIOXYGENASE, . Treffer: 33

2022

Fellendorf, FT; Bonkat, N; Dalkner, N; Schönthaler, EMD; Manchia, M; Fuchs, D; Reininghaus, EZ Indoleamine 2,3-dioxygenase (IDO)-activity in Severe Psychiatric Disorders: A Systemic Review.
Curr Top Med Chem. 2022; 22(25):2107-2118 Doi: 10.2174/1568026622666220718155616
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Fellendorf, FT; Manchia, M; Squassina, A; Pisanu, C; Dall'Acqua, S; Sut, S; Nasini, S; Congiu, D; Reininghaus, EZ; Garzilli, M; Guiso, B; Suprani, F; Paribello, P; Pulcinelli, V; Iaselli, MN; Pinna, I; Somaini, G; Arru, L; Corrias, C; Pinna, F; Carpiniello, B; Comai, S Is Poor Lithium Response in Individuals with Bipolar Disorder Associated with Increased Degradation of Tryptophan along the Kynurenine Pathway? Results of an Exploratory Study.
J Clin Med. 2022; 11(9): Doi: 10.3390/jcm11092517 [OPEN ACCESS]
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2021

Fellendorf, FT; Gostner, JM; Lenger, M; Platzer, M; Birner, A; Maget, A; Queissner, R; Tmava-Berisha, A; Pater, CA; Ratzenhofer, M; Wagner-Skacel, J; Bengesser, SA; Dalkner, N; Fuchs, D; Reininghaus, EZ Tryptophan Metabolism in Bipolar Disorder in a Longitudinal Setting.
Antioxidants (Basel). 2021; 10(11): Doi: 10.3390/antiox10111795 [OPEN ACCESS]
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Zulpaite, R; Miknevicius, P; Leber, B; Strupas, K; Stiegler, P; Schemmer, P Tryptophan Metabolism via Kynurenine Pathway: Role in Solid Organ Transplantation.
Int J Mol Sci. 2021; 22(4): Doi: 10.3390/ijms22041921 [OPEN ACCESS]
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2018

Zardoya-Laguardia, P; Blaschitz, A; Hirschmugl, B; Lang, I; Herzog, SA; Nikitina, L; Gauster, M; Häusler, M; Cervar-Zivkovic, M; Karpf, E; Maghzal, GJ; Stanley, CP; Stocker, R; Wadsack, C; Frank, S; Sedlmayr, P Endothelial indoleamine 2,3-dioxygenase-1 regulates the placental vascular tone and is deficient in intrauterine growth restriction and pre-eclampsia.
Sci Rep. 2018; 8(1): 5488-5488. Doi: 10.1038/s41598-018-23896-0 [OPEN ACCESS]
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2017

Fechter, K; Dorronsoro, A; Jakobsson, E; Ferrin, I; Lang, V; Sepulveda, P; Pennington, DJ; Trigueros, C IFNγ Regulates Activated Vδ2+ T Cells through a Feedback Mechanism Mediated by Mesenchymal Stem Cells.
PLoS One. 2017; 12(1): e0169362-e0169362. Doi: 10.1371/journal.pone.0169362 [OPEN ACCESS]
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Nagy, BM; Nagaraj, C; Meinitzer, A; Sharma, N; Papp, R; Foris, V; Ghanim, B; Kwapiszewska, G; Kovacs, G; Klepetko, W; Pieber, TR; Mangge, H; Olschewski, H; Olschewski, A Importance of kynurenine in pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol. 2017; 313(5):L741-L751 Doi: 10.1152/ajplung.00517.2016 [OPEN ACCESS]
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2015

Baranyi, A; Meinitzer, A; Breitenecker, RJ; Amouzadeh-Ghadikolai, O; Stauber, R; Rothenhäusler, HB Quinolinic Acid Responses during Interferon-α-Induced Depressive Symptomatology in Patients with Chronic Hepatitis C Infection - A Novel Aspect for Depression and Inflammatory Hypothesis.
PLoS One. 2015; 10(9):e0137022-e0137022 Doi: 10.1371/journal.pone.0137022 [OPEN ACCESS]
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2014

Gostner, J; Ciardi, C; Becker, K; Fuchs, D; Sucher, R Immunoregulatory impact of food antioxidants.
Curr Pharm Des. 2014; 20(6):840-9 Doi: 10.2174/13816128113199990047
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Mangge, H; Becker, K; Fuchs, D; Gostner, JM Antioxidants, inflammation and cardiovascular disease.
World J Cardiol. 2014; 6(6):462-477 Doi: 10.4330/wjc.v6.i6.462 [OPEN ACCESS]
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Mangge, H; Stelzer, I; Reininghaus, EZ; Weghuber, D; Postolache, TT; Fuchs, D Disturbed tryptophan metabolism in cardiovascular disease.
Curr Med Chem. 2014; 21(17):1931-1937 Doi: 10.2174/0929867321666140304105526 [OPEN ACCESS]
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Reininghaus, EZ; McIntyre, RS; Reininghaus, B; Geisler, S; Bengesser, SA; Lackner, N; Hecht, K; Birner, A; Kattnig, F; Unterweger, R; Kapfhammer, HP; Zelzer, S; Fuchs, D; Mangge, H Tryptophan breakdown is increased in euthymic overweight individuals with bipolar disorder: a preliminary report.
Bipolar Disord. 2014; 16(4):432-440 Doi: 10.1111/bdi.12166
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Sedlmayr, P; Blaschitz, A; Stocker, R The role of placental tryptophan catabolism.
Front Immunol. 2014; 5(7):230-230 Doi: 10.3389/fimmu.2014.00230 [OPEN ACCESS]
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2013

Becker, JC; Andersen, MH; Schrama, D; Thor Straten, P Immune-suppressive properties of the tumor microenvironment.
Cancer Immunol Immunother. 2013; 62(7):1137-1148 Doi: 10.1007/s00262-013-1434-6
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Gostner, JM; Becker, K; Fuchs, D; Sucher, R Redox regulation of the immune response.
Redox Rep. 2013; 18(3):88-94 Doi: 10.1179/1351000213Y.0000000044 [OPEN ACCESS]
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2012

Sedlmayr, P; Blaschitz, A Placental expression of indoleamine 2,3-dioxygenase.
Wien Med Wochenschr. 2012; 162(9-10): 214-219. Doi: 10.1007/s10354-012-0082-3
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2011

Blaschitz, A; Gauster, M; Fuchs, D; Lang, I; Maschke, P; Ulrich, D; Karpf, E; Takikawa, O; Schimek, MG; Dohr, G; Sedlmayr, P Vascular endothelial expression of indoleamine 2,3-dioxygenase 1 forms a positive gradient towards the feto-maternal interface.
PLoS One. 2011; 6(7):e21774-e21774 Doi: 10.1371/journal.pone.0021774 [OPEN ACCESS]
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Schroecksnadel, S; Sucher, R; Kurz, K; Fuchs, D; Brandacher, G Influence of immunosuppressive agents on tryptophan degradation and neopterin production in human peripheral blood mononuclear cells.
Transpl Immunol. 2011; 25(2-3):119-23 Doi: 10.1016/j.trim.2011.06.005
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2010

Sucher, R; Kurz, K; Weiss, G; Margreiter, R; Fuchs, D; Brandacher, G IDO-Mediated Tryptophan Degradation in the Pathogenesis of Malignant Tumor Disease.
Int J Tryptophan Res. 2010; 3:113-20 Doi: 10.4137/ijtr.s4157 [OPEN ACCESS]
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2007

Hainz, U; Jürgens, B; Wekerle, T; Seidel, MG; Heitger, A Indoleamine 2,3-dioxygenase in hematopoietic stem cell transplantation.
Curr Drug Metab. 2007; 8(3):267-272 Doi: 10.2174/138920007780362554
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Wobser, M; Voigt, H; Houben, R; Eggert, AO; Freiwald, M; Kaemmerer, U; Kaempgen, E; Schrama, D; Becker, JC Dendritic cell based antitumor vaccination: impact of functional indoleamine 2,3-dioxygenase expression.
Cancer Immunol Immunother. 2007; 56(7):1017-1024 Doi: 10.1007/s00262-006-0256-1
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2005

Hainz, U; Obexer, P; Winkler, C; Sedlmayr, P; Takikawa, O; Greinix, H; Lawitschka, A; Pötschger, U; Fuchs, D; Ladisch, S; Heitger, A Monocyte-mediated T-cell suppression and augmented monocyte tryptophan catabolism after human hematopoietic stem-cell transplantation.
BLOOD. 2005; 105(10): 4127-4134. Doi: 10.1182/blood-2004-05-1726 [OPEN ACCESS]
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2004

Cupurdija, K; Azzola, D; Hainz, U; Gratchev, A; Heitger, A; Takikawa, O; Goerdt, S; Wintersteiger, R; Dohr, G; Sedlmayr, P Macrophages of human first trimester decidua express markers associated to alternative activation.
AMER J REPROD IMMUNOL. 2004; 51(2): 117-122. Doi: 10.1046/j.8755-8920.2003.00128.x
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2003

Sedlmayr, P; Semlitsch, M; Gebru, G; Karpf, E; Reich, O; Tang, T; Wintersteiger, R; Takikawa, O; Dohr, G Expression of indoleamine 2,3-dioxygenase in carcinoma of human endometrium and uterine cervix.
ADVAN EXPERIMENT MED BIOL. 2003; 527: 91-95. Doi: 10.1007/978-1-4615-0135-0_10
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2002

Sedlmayr, P; Blaschitz, A; Wintersteiger, R; Semlitsch, M; Hammer, A; MacKenzie, CR; Walcher, W; Reich, O; Takikawa, O; Dohr, G Localization of indoleamine 2,3-dioxygenase in human female reproductive organs and the placenta.
Mol Hum Reprod. 2002; 8(4):385-391 Doi: 10.1093%2Fmolehr%2F8.4.385 [OPEN ACCESS]
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2000

Widner, B; Leblhuber, F; Walli, J; Tilz, GP; Demel, U; Fuchs, D Tryptophan degradation and immune activation in Alzheimer's disease.
J Neural Transm. 2000; 107(3):343-353 Doi: 10.1007%2Fs007020050029
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1991

Fuchs, D; Möller, AA; Reibnegger, G; Werner, ER; Werner-Felmayer, G; Dierich, MP; Wachter, H Increased endogenous interferon-gamma and neopterin correlate with increased degradation of tryptophan in human immunodeficiency virus type 1 infection.
Immunol Lett. 1991; 28(3):207-211 Doi: 10.1016/0165-2478(91)90005-U
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1990

Fuchs, D; Möller, AA; Reibnegger, G; Stöckle, E; Werner, ER; Wachter, H Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms.
J Acquir Immune Defic Syndr. 1990; 3(9):873-876
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Werner-Felmayer, G; Werner, ER; Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1) upon cytokine treatment.
Cancer Res. 1990; 50(10):2863-2867 [OPEN ACCESS]
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1989

Werner, ER; Werner-Felmayer, G; Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma.
Biochem J. 1989; 262(3):861-866 Doi: 10.1042/bj2620861 [OPEN ACCESS]
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Werner-Felmayer, G; Werner, ER; Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H Characteristics of interferon induced tryptophan metabolism in human cells in vitro.
Biochim Biophys Acta. 1989; 1012(2):140-147 Doi: 10.1016/0167-4889(89)90087-6
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Werner-Felmayer, G; Werner, ER; Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H Tumour necrosis factor-alpha and lipopolysaccharide enhance interferon-induced tryptophan degradation and pteridine synthesis in human cells.
Biol Chem Hoppe Seyler. 1989; 370(9):1063-1069 Doi: 10.1515/bchm3.1989.370.2.1063
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1988

Werner, ER; Werner-Felmayer, G; Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H Influence of interferon-gamma and extracellular tryptophan on indoleamine 2,3-dioxygenase activity in T24 cells as determined by a non-radiometric assay.
Biochem J. 1988; 256(2):537-541 Doi: 10.1042/bj2560537 [OPEN ACCESS]
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